Title: Preparation of a polymer-supported chiral 1,2-diamine and its application to the asymmetric hydrogenation of aromatic ketones
Abstract: Polymer-supported chiral 1,2-diamines were prepared by two methods including (1) chemical modification of a Merrifield-type resin with a chiral 1,2-diamine and (2) polymerization of a 1,2-diamine monomer. The polymeric complex formed by the polymer-supported 1,2-diamine and RuCl2-BINAP was used for the asymmetric hydrogenation of aromatic ketones to afford the corresponding secondary alcohols in quantitative yields with high enantioselectivities up to 99% ee in the asymmetric hydrogenation. The polymeric catalyst could be reused many times without any loss of activity or enantioselectivity.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 10
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