Publication Information

{'id': 'https://openalex.org/W1991185062', 'doi': 'https://doi.org/10.1073/pnas.0801295105', 'title': 'Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules', 'display_name': 'Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules', 'publication_year': 2008, 'publication_date': '2008-03-29', 'ids': {'openalex': 'https://openalex.org/W1991185062', 'doi': 'https://doi.org/10.1073/pnas.0801295105', 'mag': '1991185062', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18375758', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2291118'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1073/pnas.0801295105', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://doi.org/10.1073/pnas.0801295105', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100398365', 'display_name': 'Zhichao Wang', 'orcid': 'https://orcid.org/0000-0002-4237-5084'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'ZhiChao Wang', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049092112', 'display_name': 'Myoung Kwon Choi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Myoung Kwon Choi', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101409404', 'display_name': 'Tatsuma Ban', 'orcid': 'https://orcid.org/0000-0001-9517-9661'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tatsuma Ban', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037249799', 'display_name': 'Hideyuki Yanai', 'orcid': 'https://orcid.org/0000-0002-0115-9000'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hideyuki Yanai', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073987050', 'display_name': 'Hideo Negishi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hideo Negishi', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114804077', 'display_name': 'Yan Lu', 'orcid': 'https://orcid.org/0009-0007-5627-7024'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yan Lu', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101745890', 'display_name': 'Tomohiko Tamura', 'orcid': 'https://orcid.org/0000-0002-9664-1747'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomohiko Tamura', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073909800', 'display_name': 'Akinori Takaoka', 'orcid': 'https://orcid.org/0000-0002-6036-3757'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akinori Takaoka', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060264000', 'display_name': 'Kazuko Nishikura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I102322052', 'display_name': 'The Wistar Institute', 'ror': 'https://ror.org/04wncat98', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I102322052']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kazuko Nishikura', 'raw_affiliation_strings': ['The Wistar Institute, Philadelphia, PA 19104'], 'affiliations': [{'raw_affiliation_string': 'The Wistar Institute, Philadelphia, PA 19104', 'institution_ids': ['https://openalex.org/I102322052']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101896608', 'display_name': 'Tadatsugu Taniguchi', 'orcid': 'https://orcid.org/0000-0001-5212-090X'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tadatsugu Taniguchi', 'raw_affiliation_strings': ['*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and'], 'affiliations': [{'raw_affiliation_string': '*Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo 113-0033, Japan; and', 'institution_ids': ['https://openalex.org/I74801974']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 18.573, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 323, 'citation_normalized_percentile': {'value': 0.999911, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '105', 'issue': '14', 'first_page': '5477', 'last_page': '5482'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11668', 'display_name': 'interferon and immune responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11668', 'display_name': 'interferon and immune responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C136449434', 'wikidata': 'https://www.wikidata.org/wiki/Q428253', 'display_name': 'Innate immune system', 'level': 3, 'score': 0.82443887}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.77426016}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6795063}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6144681}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.6097461}, {'id': 'https://openalex.org/C88045685', 'wikidata': 'https://www.wikidata.org/wiki/Q174576', 'display_name': 'Activator (genetics)', 'level': 3, 'score': 0.50814605}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.45098293}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.44214034}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.441725}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.30469954}], 'mesh': [{'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D007113', 'descriptor_name': 'Immunity, Innate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000243', 'descriptor_name': 'Adenosine Deaminase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000243', 'descriptor_name': 'Adenosine Deaminase', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019281', 'descriptor_name': 'Dimerization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007370', 'descriptor_name': 'Interferon Type I', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007370', 'descriptor_name': 'Interferon Type I', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016601', 'descriptor_name': 'RNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1073/pnas.0801295105', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2291118', 'pdf_url': 'https://europepmc.org/articles/pmc2291118?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291118', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18375758', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1073/pnas.0801295105', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 32, 'referenced_works': ['https://openalex.org/W1552311056', 'https://openalex.org/W1567114372', 'https://openalex.org/W1605738254', 'https://openalex.org/W1964442232', 'https://openalex.org/W1972784467', 'https://openalex.org/W1975215291', 'https://openalex.org/W1993832002', 'https://openalex.org/W2006462446', 'https://openalex.org/W2009127910', 'https://openalex.org/W2014127990', 'https://openalex.org/W2017515700', 'https://openalex.org/W2025384456', 'https://openalex.org/W2028575270', 'https://openalex.org/W2028792773', 'https://openalex.org/W203370464', 'https://openalex.org/W2039043740', 'https://openalex.org/W2046013214', 'https://openalex.org/W2051317205', 'https://openalex.org/W2053220110', 'https://openalex.org/W2063538505', 'https://openalex.org/W2083443360', 'https://openalex.org/W2089712328', 'https://openalex.org/W2100665873', 'https://openalex.org/W2101363646', 'https://openalex.org/W2102025585', 'https://openalex.org/W2120276739', 'https://openalex.org/W2133449490', 'https://openalex.org/W2141425521', 'https://openalex.org/W2148304657', 'https://openalex.org/W2161048703', 'https://openalex.org/W2916483810', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W581377774', 'https://openalex.org/W4285733331', 'https://openalex.org/W2565121077', 'https://openalex.org/W2316042956', 'https://openalex.org/W2190283986', 'https://openalex.org/W2158827209', 'https://openalex.org/W2130166758', 'https://openalex.org/W2066136773', 'https://openalex.org/W1987802636', 'https://openalex.org/W1495541589'], 'abstract_inverted_index': {'DNA,': [0], 'whether': [1], 'it': [2, 76], 'is': [3], 'microbe-derived': [4], 'or': [5, 132], 'host-derived,': [6], 'evokes': [7], 'immune': [8, 43, 138, 163], 'responses': [9], 'when': [10], 'exposed': [11], 'to': [12, 31], 'the': [13, 41, 46, 51, 54, 91, 99, 113, 124, 147, 154], 'cytosol': [14], 'of': [15, 24, 53, 95, 102, 116, 126, 149], 'a': [16, 36, 109], 'cell.': [17], 'We': [18, 63, 87], 'previously': [19], 'reported': [20], 'that': [21, 39, 66, 75, 90], 'DNA-dependent': [22], 'activator': [23], 'IFN': [25, 105], 'regulatory': [26, 156], 'factors': [27], '(DAI),': [28], 'also': [29, 88], 'referred': [30], 'as': [32, 35], 'DLM-1/ZBP1,': [33], 'functions': [34], 'DNA': [37, 71, 128], 'sensor': [38], 'activates': [40], 'innate': [42, 137], 'system.': [44], 'In': [45], 'present': [47], 'study,': [48], 'we': [49, 120], 'examined': [50], 'regulation': [52], 'complex': [55, 155], 'DNA-sensing': [56], 'system': [57], 'by': [58], 'DAI': [59, 67, 96, 117, 150], 'and': [60, 74, 152, 161], 'other': [61], 'molecules.': [62], 'first': [64], 'show': [65, 89], 'directly': [68], 'interacts': [69], 'with': [70], 'in': [72, 84, 98, 142], 'vitro': [73], 'requires': [77], 'three': [78], 'DNA-binding': [79], 'domains': [80], 'for': [81, 112, 123], 'full': [82], 'activation': [83, 101, 151], 'vivo': [85], '.': [86], 'artificially': [92], 'induced': [93], 'dimerization': [94], 'results': [97, 141], 'DNA-independent': [100], 'type': [103], 'I': [104], 'genes,': [106], 'thereby': [107], 'providing': [108], 'better': [110], 'understanding': [111], 'molecular': [114], 'basis': [115], 'activation.': [118], 'Furthermore,': [119], 'provide': [121, 144], 'evidence': [122], 'presence': [125], 'additional': [127], 'sensors,': [129], 'either': [130], 'positively': [131], 'negatively': [133], 'regulating': [134], 'cytosolic': [135], 'DNA-mediated': [136, 159], 'responses.': [139, 164], 'These': [140], 'toto': [143], 'insights': [145], 'into': [146], 'mechanism': [148], 'reveal': [153], 'mechanisms': [157], 'underlying': [158], 'protective': [160], 'pathologic': [162]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1991185062', 'counts_by_year': [{'year': 2024, 'cited_by_count': 16}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 15}, {'year': 2021, 'cited_by_count': 13}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 20}, {'year': 2013, 'cited_by_count': 26}, {'year': 2012, 'cited_by_count': 23}], 'updated_date': '2025-01-06T12:26:43.721894', 'created_date': '2016-06-24'}