Ageing and PARP

Name: Work Video:
Duration: 3 min 30 s
Alexander Bürkle; Jörg Diefenbach; Christine Brabeck; Sascha Beneke
{'id': 'https://openalex.org/W1990559952', 'doi': 'https://doi.org/10.1016/j.phrs.2005.02.008', 'title': 'Ageing and PARP', 'display_name': 'Ageing and PARP', 'publication_year': 2005, 'publication_date': '2005-04-08', 'ids': {'openalex': 'https://openalex.org/W1990559952', 'doi': 'https://doi.org/10.1016/j.phrs.2005.02.008', 'mag': '1990559952', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15911337'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.phrs.2005.02.008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S54485712', 'display_name': 'Pharmacological Research', 'issn_l': '1043-6618', 'issn': ['1043-6618', '1096-1186'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5021983212', 'display_name': 'Alexander Bürkle', 'orcid': 'https://orcid.org/0000-0003-1069-2656'}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Alexander Bürkle', 'raw_affiliation_strings': ['Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111590044', 'display_name': 'Jörg Diefenbach', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Jörg Diefenbach', 'raw_affiliation_strings': ['Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022127675', 'display_name': 'Christine Brabeck', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Christine Brabeck', 'raw_affiliation_strings': ['Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068077927', 'display_name': 'Sascha Beneke', 'orcid': 'https://orcid.org/0000-0002-1998-7373'}, 'institutions': [{'id': 'https://openalex.org/I189712700', 'display_name': 'University of Konstanz', 'ror': 'https://ror.org/0546hnb39', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I189712700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Sascha Beneke', 'raw_affiliation_strings': ['Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany'], 'affiliations': [{'raw_affiliation_string': 'Molecular Toxicology Group, Box X911, University of Konstanz, D-78457 Konstanz, Germany', 'institution_ids': ['https://openalex.org/I189712700']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.048, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 50, 'citation_normalized_percentile': {'value': 0.776096, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '52', 'issue': '1', 'first_page': '93', 'last_page': '99'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11914', 'display_name': 'PARP inhibition in cancer therapy', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11914', 'display_name': 'PARP inhibition in cancer therapy', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10294', 'display_name': 'Cell death mechanisms and regulation', 'score': 0.9789, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ribose', 'display_name': 'Ribose', 'score': 0.67436236}], 'concepts': [{'id': 'https://openalex.org/C182979987', 'wikidata': 'https://www.wikidata.org/wiki/Q3907241', 'display_name': 'Poly ADP ribose polymerase', 'level': 4, 'score': 0.8969202}, {'id': 'https://openalex.org/C134935766', 'wikidata': 'https://www.wikidata.org/wiki/Q210538', 'display_name': 'DNA repair', 'level': 3, 'score': 0.6826793}, {'id': 'https://openalex.org/C2779461342', 'wikidata': 'https://www.wikidata.org/wiki/Q59817493', 'display_name': 'Ribose', 'level': 3, 'score': 0.67436236}, {'id': 'https://openalex.org/C53345823', 'wikidata': 'https://www.wikidata.org/wiki/Q5531554', 'display_name': 'Gene isoform', 'level': 3, 'score': 0.57478595}, {'id': 'https://openalex.org/C82381507', 'wikidata': 'https://www.wikidata.org/wiki/Q416878', 'display_name': 'Polymerase', 'level': 3, 'score': 0.5736714}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.5553509}, {'id': 'https://openalex.org/C500499127', 'wikidata': 'https://www.wikidata.org/wiki/Q332154', 'display_name': 'Ageing', 'level': 2, 'score': 0.53080493}, {'id': 'https://openalex.org/C2776759703', 'wikidata': 'https://www.wikidata.org/wiki/Q1066907', 'display_name': 'Longevity', 'level': 2, 'score': 0.49191403}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.45905387}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4390109}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.41305444}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39173836}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.38100004}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.33303237}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.21215612}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.09141308}], 'mesh': [{'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011065', 'descriptor_name': 'Poly(ADP-ribose) Polymerases', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008136', 'descriptor_name': 'Longevity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011065', 'descriptor_name': 'Poly(ADP-ribose) Polymerases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.phrs.2005.02.008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S54485712', 'display_name': 'Pharmacological Research', 'issn_l': '1043-6618', 'issn': ['1043-6618', '1096-1186'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15911337', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 65, 'referenced_works': ['https://openalex.org/W1514969926', 'https://openalex.org/W1515063332', 'https://openalex.org/W1517847739', 'https://openalex.org/W1670619327', 'https://openalex.org/W1848063234', 'https://openalex.org/W1936994465', 'https://openalex.org/W1966888005', 'https://openalex.org/W1968309671', 'https://openalex.org/W1980647462', 'https://openalex.org/W1983673827', 'https://openalex.org/W1990960553', 'https://openalex.org/W1991042231', 'https://openalex.org/W1998000773', 'https://openalex.org/W1998835486', 'https://openalex.org/W1999872096', 'https://openalex.org/W2001431040', 'https://openalex.org/W2004808899', 'https://openalex.org/W2005458257', 'https://openalex.org/W2007859567', 'https://openalex.org/W2025662299', 'https://openalex.org/W2032205501', 'https://openalex.org/W2032407757', 'https://openalex.org/W2033761616', 'https://openalex.org/W2036950607', 'https://openalex.org/W2037316481', 'https://openalex.org/W2046175921', 'https://openalex.org/W2046833562', 'https://openalex.org/W2047807761', 'https://openalex.org/W2054186013', 'https://openalex.org/W2057706543', 'https://openalex.org/W2063696945', 'https://openalex.org/W2066253067', 'https://openalex.org/W2068470198', 'https://openalex.org/W2070279067', 'https://openalex.org/W2072455635', 'https://openalex.org/W2075174658', 'https://openalex.org/W2078651829', 'https://openalex.org/W2084060660', 'https://openalex.org/W2088175135', 'https://openalex.org/W2094618951', 'https://openalex.org/W2102647168', 'https://openalex.org/W2103259804', 'https://openalex.org/W2112655328', 'https://openalex.org/W2112671059', 'https://openalex.org/W2113511334', 'https://openalex.org/W2117062102', 'https://openalex.org/W2117258496', 'https://openalex.org/W2121272379', 'https://openalex.org/W2122740168', 'https://openalex.org/W2125044969', 'https://openalex.org/W2125628261', 'https://openalex.org/W2128016549', 'https://openalex.org/W2128974910', 'https://openalex.org/W2135963451', 'https://openalex.org/W2149464818', 'https://openalex.org/W2150950031', 'https://openalex.org/W2154087197', 'https://openalex.org/W2155169828', 'https://openalex.org/W2158944861', 'https://openalex.org/W2164091821', 'https://openalex.org/W2167569270', 'https://openalex.org/W2168496620', 'https://openalex.org/W2524634354', 'https://openalex.org/W267892546', 'https://openalex.org/W4234794870'], 'related_works': ['https://openalex.org/W653560493', 'https://openalex.org/W3032821801', 'https://openalex.org/W2594674378', 'https://openalex.org/W2282899891', 'https://openalex.org/W2140029877', 'https://openalex.org/W2116804853', 'https://openalex.org/W2090245768', 'https://openalex.org/W2082002010', 'https://openalex.org/W2003721498', 'https://openalex.org/W1541804201'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1990559952', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-16T08:57:02.948867', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
