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142], 'increase': [98], 'α-secretase': [99, 110, 134, 197], 'activity': [100, 111, 198], 'in': [101, 105, 131, 193], 'dose-dependent': [103], 'manner': [104], 'PC12': [106], 'cells.': [107], 'increased': [109, 196], 'can': [112], 'be': [113], 'partially': [114], 'blocked': [115, 165], 'pretreatment': [117, 167], 'with': [118, 138, 168, 181], 'brefeldin': [119, 144, 169], 'A,': [120], 'an': [121], 'intracellular': [122], 'transport': [124], 'inhibitor,': [125], 'suggesting': [126], 'involvement': [127], 'trafficking': [130, 201], 'regulated': [133], 'activity.': [135], 'In': [136], 'accordance': [137], 'this,': [139], 'A': [145], 'also': [146], 'decreased': [147], 'release': [149], 'induced': [150], 'promoted': [154, 177], 'ADAM10': [155, 180], 'transported': [156], 'membrane': [159], 'fraction,': [160], 'this': [162], 'effect': [163], 'was': [164], 'A.': [170], 'immunocytochemistry': [172], 'staining': [173], 'revealed': [174], 'colocalization': [178], 'PKCα': [182], 'PKCε': [184], 'isoforms.': [185], 'These': [186], 'data': [187], 'suggest': [188], 'novel': [190], 'pharmacological': [191], 'mechanism': [192], 'which': [194], 'via': [199], 'related': [202], 'mechanism.': [203]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1990345392', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-16T22:22:52.645211', 'created_date': '2016-06-24'}