Title: The boronic acid mannich reaction: A new method for the synthesis of geometrically pure allylamines
Abstract: Reaction of vinyl boronic acids with the adducts of secondary amines and paraformaldehyde gives tertiary allylamines with the same geometry. This simple and practical method was used for the synthesis of geometrically pure naftifine, a potent antifungal agent.
Publication Year: 1993
Publication Date: 1993-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 403
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