Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1990110463', 'doi': 'https://doi.org/10.1126/science.2169649', 'title': 'An Insertion in the Human Thyrotropin Receptor Critical for High Affinity Hormone Binding', 'display_name': 'An Insertion in the Human Thyrotropin Receptor Critical for High Affinity Hormone Binding', 'publication_year': 1990, 'publication_date': '1990-09-21', 'ids': {'openalex': 'https://openalex.org/W1990110463', 'doi': 'https://doi.org/10.1126/science.2169649', 'mag': '1990110463', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2169649'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.2169649', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111693886', 'display_name': 'Harry Wadsworth', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Harry L. Wadsworth', 'raw_affiliation_strings': ['Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085029122', 'display_name': 'Gregorio D. Chazenbalk', 'orcid': 'https://orcid.org/0000-0003-2065-3343'}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gregorio D. Chazenbalk', 'raw_affiliation_strings': ['Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031642047', 'display_name': 'Yuji Nagayama', 'orcid': 'https://orcid.org/0000-0002-5058-9349'}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yuji Nagayama', 'raw_affiliation_strings': ['Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027192215', 'display_name': 'Diego Russo', 'orcid': 'https://orcid.org/0000-0001-7559-1595'}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Diego Russo', 'raw_affiliation_strings': ['Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5108207769', 'display_name': 'Basil Rapoport', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1315708478', 'display_name': 'San Francisco VA Medical Center', 'ror': 'https://ror.org/049peqw80', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1315708478', 'https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210125474', 'https://openalex.org/I4210143381']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Basil Rapoport', 'raw_affiliation_strings': ['Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine and the Thyroid Molecular Biology Unit, Veterans Administration Medical Center, San Francisco, CA 94121, and Department of Medicine, University of California, San Francisco, CA 94143.', 'institution_ids': ['https://openalex.org/I1315708478', 'https://openalex.org/I180670191']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 22.488, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 153, 'citation_normalized_percentile': {'value': 0.899118, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '249', 'issue': '4975', 'first_page': '1423', 'last_page': '1425'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10960', 'display_name': 'Hypothalamic control of reproductive hormones', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10960', 'display_name': 'Hypothalamic control of reproductive hormones', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.993, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10293', 'display_name': 'Thyroid Disorders and Treatments', 'score': 0.9845, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thyrotropin-receptor', 'display_name': 'Thyrotropin receptor', 'score': 0.8175136}, {'id': 'https://openalex.org/keywords/thyrotropin-releasing-hormone-receptor', 'display_name': 'Thyrotropin-releasing hormone receptor', 'score': 0.51956725}], 'concepts': [{'id': 'https://openalex.org/C2777608072', 'wikidata': 'https://www.wikidata.org/wiki/Q4862366', 'display_name': 'Thyrotropin receptor', 'level': 4, 'score': 0.8175136}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.6957302}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.6919645}, {'id': 'https://openalex.org/C133603901', 'wikidata': 'https://www.wikidata.org/wiki/Q14905267', 'display_name': 'Thyrotropin-releasing hormone receptor', 'level': 5, 'score': 0.51956725}, {'id': 'https://openalex.org/C2778575703', 'wikidata': 'https://www.wikidata.org/wiki/Q50265477', 'display_name': 'Luteinizing hormone', 'level': 3, 'score': 0.51207405}, {'id': 'https://openalex.org/C23589133', 'wikidata': 'https://www.wikidata.org/wiki/Q412005', 'display_name': 'Hormone receptor', 'level': 4, 'score': 0.48151097}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4614751}, {'id': 'https://openalex.org/C16318435', 'wikidata': 'https://www.wikidata.org/wiki/Q149299', 'display_name': 'Mutagenesis', 'level': 4, 'score': 0.4477522}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.44674668}, {'id': 'https://openalex.org/C167625842', 'wikidata': 'https://www.wikidata.org/wiki/Q899763', 'display_name': 'Peptide sequence', 'level': 3, 'score': 0.4439526}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.4422521}, {'id': 'https://openalex.org/C108625454', 'wikidata': 'https://www.wikidata.org/wiki/Q187126', 'display_name': 'Glycoprotein', 'level': 2, 'score': 0.4176929}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.38883764}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37896645}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.37532094}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.27776352}, {'id': 'https://openalex.org/C526584372', 'wikidata': 'https://www.wikidata.org/wiki/Q16399', 'display_name': 'Thyroid', 'level': 2, 'score': 0.22041276}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.09767553}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.09180033}, {'id': 'https://openalex.org/C2776652619', 'wikidata': 'https://www.wikidata.org/wiki/Q16483', 'display_name': "Graves' disease", 'level': 3, 'score': 0.05480805}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.05150515}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D011989', 'descriptor_name': 'Receptors, Thyrotropin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013972', 'descriptor_name': 'Thyrotropin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002872', 'descriptor_name': 'Chromosome Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002999', 'descriptor_name': 'Clone Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015345', 'descriptor_name': 'Oligonucleotide Probes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011989', 'descriptor_name': 'Receptors, Thyrotropin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011989', 'descriptor_name': 'Receptors, Thyrotropin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013972', 'descriptor_name': 'Thyrotropin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013972', 'descriptor_name': 'Thyrotropin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.2169649', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2169649', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W1954929088', 'https://openalex.org/W1970725961', 'https://openalex.org/W2012527285', 'https://openalex.org/W2019972073', 'https://openalex.org/W2022836621', 'https://openalex.org/W2036931150', 'https://openalex.org/W2041084319', 'https://openalex.org/W2041658859', 'https://openalex.org/W2044458947', 'https://openalex.org/W2047286461', 'https://openalex.org/W2059665365', 'https://openalex.org/W2085485608', 'https://openalex.org/W2093909923', 'https://openalex.org/W2138012783', 'https://openalex.org/W2138270253', 'https://openalex.org/W2152255652', 'https://openalex.org/W266260733'], 'related_works': ['https://openalex.org/W994394052', 'https://openalex.org/W4290673266', 'https://openalex.org/W2809230418', 'https://openalex.org/W2094599840', 'https://openalex.org/W2089816992', 'https://openalex.org/W2058774648', 'https://openalex.org/W2035933067', 'https://openalex.org/W2035004741', 'https://openalex.org/W1968552800', 'https://openalex.org/W191703817'], 'abstract_inverted_index': {'Thyrotropin': [0], '(TSH),': [1], 'luteinizing': [2], 'hormone': [3], '(LH),': [4], 'and': [5, 37, 46, 88, 135], 'chorionic': [6], 'gonadotropin': [7], '(CG)': [8], 'are': [9], 'structurally': [10], 'related': [11], 'glycoprotein': [12], 'hormones,': [13], 'which': [14], 'bind': [15], 'to': [16, 77, 107, 125], 'receptors': [17, 39], 'that': [18], 'share': [19], 'a': [20], 'high': [21], 'degree': [22], 'of': [23, 28, 34, 44, 54, 61, 70, 100, 120, 130], 'sequence': [24], 'similarity.': [25], 'However,': [26], 'comparison': [27], 'the': [29, 35, 51, 55, 71, 101, 117, 121], 'primary': [30], 'amino': [31, 48, 118], 'acid': [32, 73, 103, 114], 'sequences': [33], 'TSH': [36, 56, 83, 87, 122, 134], 'LH-CG': [38], 'reveals': [40], 'two': [41], 'unique': [42], 'insertions': [43, 63], '8': [45], '50': [47], 'acids': [49], 'in': [50], 'extracellular': [52], 'domain': [53], 'receptor.': [57], 'The': [58], 'functional': [59], 'significance': [60], 'these': [62, 110], 'were': [64], 'determined': [65], 'by': [66], 'site-directed': [67], 'mutagenesis.': [68], 'Deletion': [69], '50-amino': [72], 'tract': [74, 115], '(residues': [75, 105], '317': [76], '366)': [78], 'had': [79], 'no': [80], 'effect': [81], 'on': [82, 86], 'binding': [84], 'or': [85, 98], 'thyroid-stimulating': [89], 'immunoglobulin': [90], '(TSI)': [91], 'biological': [92], 'activities.': [93, 111], 'In': [94], 'contrast,': [95], 'either': [96], 'deletion': [97], 'substitution': [99], 'eight-amino': [102, 113], 'region': [104], '38': [106], '45)': [108], 'abolished': [109], 'This': [112], 'near': [116], 'terminus': [119], 'receptor': [123], 'appears': [124], 'be': [126], 'an': [127], 'important': [128], 'site': [129], 'interaction': [131], 'for': [132], 'both': [133], 'TSI.': [136]}, 'abstract_inverted_index_v3': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1990110463', 'counts_by_year': [{'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2025-01-25T10:07:04.777018', 'created_date': '2016-06-24'}