Publication Information

{'id': 'https://openalex.org/W1990004560', 'doi': 'https://doi.org/10.1097/00006123-199611000-00024', 'title': 'Impact of Cerebral Perfusion Pressure and Autoregulation on Intracranial Dynamics: A Modeling Study', 'display_name': 'Impact of Cerebral Perfusion Pressure and Autoregulation on Intracranial Dynamics: A Modeling Study', 'publication_year': 1996, 'publication_date': '1996-11-01', 'ids': {'openalex': 'https://openalex.org/W1990004560', 'doi': 'https://doi.org/10.1097/00006123-199611000-00024', 'mag': '1990004560', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8905758'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00006123-199611000-00024', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111727011', 'display_name': 'Neurosurgery', 'issn_l': '0148-396X', 'issn': ['0148-396X', '1081-1281', '1524-4040'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081554960', 'display_name': 'Marco Giulioni', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210152184', 'display_name': 'Ospedale Bellaria', 'ror': 'https://ror.org/05fz2yc38', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210119117', 'https://openalex.org/I4210152184']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Marco Giulioni', 'raw_affiliation_strings': ['Department of Neurosurgery, Bellaria Hospital, Bologna, Italy.'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Bellaria Hospital, Bologna, Italy.', 'institution_ids': ['https://openalex.org/I4210152184']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060730893', 'display_name': 'Mauro Ursino', 'orcid': 'https://orcid.org/0000-0002-0911-0308'}, 'institutions': [{'id': 'https://openalex.org/I9360294', 'display_name': 'University of Bologna', 'ror': 'https://ror.org/01111rn36', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I9360294']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Mauro Ursino', 'raw_affiliation_strings': ['Department of Electronics, Computer Science, and Systems, University of Bologna, Bologna, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Electronics, Computer Science, and Systems, University of Bologna, Bologna, Italy', 'institution_ids': ['https://openalex.org/I9360294']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.754, 'has_fulltext': False, 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.713939, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '39', 'issue': '5', 'first_page': '1005', 'last_page': '1015'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10706', 'display_name': 'Traumatic Brain Injury and Neurovascular Disturbances', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10706', 'display_name': 'Traumatic Brain Injury and Neurovascular Disturbances', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10977', 'display_name': 'Optical Imaging and Spectroscopy Techniques', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10378', 'display_name': 'Advanced MRI Techniques and Applications', 'score': 0.9921, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cerebral-autoregulation', 'display_name': 'Cerebral autoregulation', 'score': 0.79774183}], 'concepts': [{'id': 'https://openalex.org/C111774379', 'wikidata': 'https://www.wikidata.org/wiki/Q1364253', 'display_name': 'Autoregulation', 'level': 3, 'score': 0.87508607}, {'id': 'https://openalex.org/C2780954326', 'wikidata': 'https://www.wikidata.org/wiki/Q1416096', 'display_name': 'Intracranial pressure', 'level': 2, 'score': 0.8161228}, {'id': 'https://openalex.org/C84359808', 'wikidata': 'https://www.wikidata.org/wiki/Q13365173', 'display_name': 'Cerebral autoregulation', 'level': 4, 'score': 0.79774183}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7913031}, {'id': 'https://openalex.org/C154281038', 'wikidata': 'https://www.wikidata.org/wiki/Q629232', 'display_name': 'Cerebral perfusion pressure', 'level': 3, 'score': 0.7412175}, {'id': 'https://openalex.org/C178853913', 'wikidata': 'https://www.wikidata.org/wiki/Q1642137', 'display_name': 'Hemodynamics', 'level': 2, 'score': 0.58589804}, {'id': 'https://openalex.org/C2779651940', 'wikidata': 'https://www.wikidata.org/wiki/Q54196', 'display_name': 'Cerebrospinal fluid', 'level': 2, 'score': 0.46658093}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.4646985}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.46294108}, {'id': 'https://openalex.org/C146957229', 'wikidata': 'https://www.wikidata.org/wiki/Q1266915', 'display_name': 'Perfusion', 'level': 2, 'score': 0.4534429}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4400084}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.43705702}, {'id': 'https://openalex.org/C157767197', 'wikidata': 'https://www.wikidata.org/wiki/Q886843', 'display_name': 'Cerebral blood flow', 'level': 2, 'score': 0.4114009}], 'mesh': [{'descriptor_ui': 'D001794', 'descriptor_name': 'Blood Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002560', 'descriptor_name': 'Cerebrovascular Circulation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D007427', 'descriptor_name': 'Intracranial Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008959', 'descriptor_name': 'Models, Neurological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001810', 'descriptor_name': 'Blood Volume', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002560', 'descriptor_name': 'Cerebrovascular Circulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003198', 'descriptor_name': 'Computer Simulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00006123-199611000-00024', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111727011', 'display_name': 'Neurosurgery', 'issn_l': '0148-396X', 'issn': ['0148-396X', '1081-1281', '1524-4040'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8905758', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.5, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W106722260', 'https://openalex.org/W1491555408', 'https://openalex.org/W1493825817', 'https://openalex.org/W1912611033', 'https://openalex.org/W1966187076', 'https://openalex.org/W1966424192', 'https://openalex.org/W1974658976', 'https://openalex.org/W1982559040', 'https://openalex.org/W1985604508', 'https://openalex.org/W2000702430', 'https://openalex.org/W2004121831', 'https://openalex.org/W2008520561', 'https://openalex.org/W2017229675', 'https://openalex.org/W2023729026', 'https://openalex.org/W2039632091', 'https://openalex.org/W2045619334', 'https://openalex.org/W2048323809', 'https://openalex.org/W2058232047', 'https://openalex.org/W2059712928', 'https://openalex.org/W2067222707', 'https://openalex.org/W2069251814', 'https://openalex.org/W2075126103', 'https://openalex.org/W2084205568', 'https://openalex.org/W2084938632', 'https://openalex.org/W2090218862', 'https://openalex.org/W2098086417', 'https://openalex.org/W2100786169', 'https://openalex.org/W2102964837', 'https://openalex.org/W2108755292', 'https://openalex.org/W2113850976', 'https://openalex.org/W2138970529', 'https://openalex.org/W2152626368', 'https://openalex.org/W2165083422', 'https://openalex.org/W2171723910', 'https://openalex.org/W2312722402', 'https://openalex.org/W2314905115', 'https://openalex.org/W2338466394', 'https://openalex.org/W2417403088', 'https://openalex.org/W376761050', 'https://openalex.org/W4252226106', 'https://openalex.org/W605904031'], 'related_works': ['https://openalex.org/W4379233127', 'https://openalex.org/W4376596107', 'https://openalex.org/W4319825722', 'https://openalex.org/W4288046334', 'https://openalex.org/W3141732236', 'https://openalex.org/W2792847384', 'https://openalex.org/W2604389455', 'https://openalex.org/W2318860532', 'https://openalex.org/W1990004560', 'https://openalex.org/W1978082518'], 'abstract_inverted_index': {'The': [0, 62], 'aim': [1], 'of': [2, 10, 27, 36, 42, 54, 67, 86, 96, 109, 129, 132, 165, 168, 182, 211, 236, 269, 303], 'this': [3], 'work': [4], 'was': [5, 47], 'to': [6, 111, 150, 257], 'study': [7, 46, 231], 'the': [8, 28, 33, 40, 65, 79, 84, 94, 107, 127, 166, 180, 194, 204, 209, 220, 233, 266, 301], 'impact': [9], 'acute': [11, 241], 'cerebral': [12, 20, 74, 174, 270], 'perfusion': [13], 'pressure': [14, 23, 104], '(CPP)': [15], 'changes': [16], 'and': [17, 25, 32, 57, 69, 76, 83, 91, 139, 177, 198, 300], 'autoregulation': [18, 87, 196, 205], 'on': [19, 89, 278, 298], 'hemodynamics,': [21], 'intracranial': [22, 55, 72, 80, 98, 133, 245, 249], '(ICP),': [24], 'estimation': [26], 'pressure-volume': [29, 81], 'index': [30], '(PVI)': [31], 'possible': [34], 'involvement': [35], 'these': [37], 'factors': [38], 'in': [39, 106, 126, 136, 193, 219, 244], 'development': [41], 'secondary': [43], 'brain': [44], 'damage.The': [45], 'performed': [48], 'by': [49, 240, 265], 'using': [50], 'a': [51, 117, 143, 156, 169, 187, 199, 224], 'mathematical': [52], 'model': [53, 63], 'hemodynamics': [56], 'cerebrospinal': [58], 'fluid': [59], '(CSF)': [60], 'dynamics.': [61, 246], 'includes': [64], 'biomechanics': [66], 'proximal': [68, 90], 'distal': [70, 92], 'arterial': [71, 103, 242], 'vessels,': [73], 'veins,': [75], 'CSF': [77, 137], 'circulation,': [78], 'relationship,': [82], 'action': [85], 'mechanisms': [88], 'vessels.In': [93], 'case': [95, 128, 181, 210], 'normal': [97], 'dynamics,': [99], 'lowering': [100], 'mean': [101, 145], 'systemic': [102], '(SAP)': [105], 'range': [108, 197], '100': [110, 149], '60': [112], 'mm': [113, 122, 152, 162, 259], 'Hg': [114], 'causes': [115], 'only': [116], 'mild': [118, 188, 225], 'ICP': [119, 159], 'increase': [120], '(+1-2': [121], 'Hg).': [123], 'In': [124, 179, 208], 'contrast,': [125], 'severe': [130], 'impairment': [131], 'dynamics': [134], '(reductions': [135], 'outflow': [138], 'storage': [140], 'capacity),': [141], 'even': [142], 'modest': [144], 'SAP': [146, 192], 'decrease': [147], '(from': [148], '90': [151, 258], 'Hg)': [153], 'may': [154, 274], 'induce': [155], 'transient': [157], 'abrupt': [158], 'rise': [160], '(+30-40': [161], 'Hg),': [163], 'because': [164], 'presence': [167], 'vicious': [170], 'cycle': [171], 'among': [172], 'CPP,': [173], 'blood': [175], 'volume,': [176], 'ICP.': [178], 'intact': [183], 'autoregulation,': [184, 213], 'PVI': [185, 214, 261], 'shows': [186], 'positive': [189], 'correlation': [190, 202, 227], 'with': [191, 223, 228, 296], 'central': [195], 'strongly': [200], 'negative': [201, 226], 'below': [203], 'lower': [206], 'limit.': [207], 'impaired': [212], 'exhibits': [215], 'higher': [216], 'values': [217], 'than': [218], 'regulated': [221], 'case,': [222], 'SAP.The': [229], 'present': [230], 'emphasizes': [232], 'relevant': [234], 'role': [235], 'CPP': [237, 251, 299], 'changes,': [238], 'elicited': [239], 'hypotension,': [243], 'To': [247], 'achieve': [248], 'stability,': [250], 'should': [252, 291], 'be': [253, 293], 'maintained': [254], 'above': [255], '80': [256], 'Hg.': [260], 'is': [262, 283], 'significantly': [263], 'affected': [264], 'active': [267], 'response': [268], 'vessels.': [271], 'Hence,': [272], 'it': [273, 282, 290], 'provide': [275], 'misleading': [276], 'information': [277, 297], 'craniospinal': [279], 'capacity': [280], 'if': [281], 'considered': [284, 294], 'as': [285], 'an': [286], 'autonomous': [287], 'index:': [288], 'rather,': [289], 'always': [292], 'together': [295], 'status': [302], 'autoregulation.': [304]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1990004560', 'counts_by_year': [{'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-04T21:30:31.148241', 'created_date': '2016-06-24'}