Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1989996481', 'doi': 'https://doi.org/10.1212/wnl.43.12.2621', 'title': 'Sequence comparisons of HTLV‐I from HAM/TSP patients and their asymptomatic spouses', 'display_name': 'Sequence comparisons of HTLV‐I from HAM/TSP patients and their asymptomatic spouses', 'publication_year': 1993, 'publication_date': '1993-12-01', 'ids': {'openalex': 'https://openalex.org/W1989996481', 'doi': 'https://doi.org/10.1212/wnl.43.12.2621', 'mag': '1989996481', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7504797'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.43.12.2621', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5046109064', 'display_name': 'Masataka Nishimura', 'orcid': 'https://orcid.org/0000-0002-3309-458X'}, 'institutions': [{'id': 'https://openalex.org/I4210146211', 'display_name': 'Utano Hospital', 'ror': 'https://ror.org/04rzagz55', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137409', 'https://openalex.org/I4210146211']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Masataka Nishimura', 'raw_affiliation_strings': ['Clinical Research Center (Dr. Nishimura), Utano National Hospital, Narutaki Ukyo-ku, Kyoto, Japan, and the Neuroimmunology Branch (Drs. McFarlin and Jacobson), National Institutes of Health, Bethesda, MD.'], 'affiliations': [{'raw_affiliation_string': 'Clinical Research Center (Dr. Nishimura), Utano National Hospital, Narutaki Ukyo-ku, Kyoto, Japan, and the Neuroimmunology Branch (Drs. McFarlin and Jacobson), National Institutes of Health, Bethesda, MD.', 'institution_ids': ['https://openalex.org/I4210146211', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111837570', 'display_name': 'Dale E. McFarlin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146211', 'display_name': 'Utano Hospital', 'ror': 'https://ror.org/04rzagz55', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137409', 'https://openalex.org/I4210146211']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Dale E. McFarlin', 'raw_affiliation_strings': ['Clinical Research Center (Dr. Nishimura), Utano National Hospital, Narutaki Ukyo-ku, Kyoto, Japan, and the Neuroimmunology Branch (Drs. McFarlin and Jacobson), National Institutes of Health, Bethesda, MD.'], 'affiliations': [{'raw_affiliation_string': 'Clinical Research Center (Dr. Nishimura), Utano National Hospital, Narutaki Ukyo-ku, Kyoto, Japan, and the Neuroimmunology Branch (Drs. McFarlin and Jacobson), National Institutes of Health, Bethesda, MD.', 'institution_ids': ['https://openalex.org/I4210146211', 'https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051578610', 'display_name': 'Steven Jacobson', 'orcid': 'https://orcid.org/0000-0003-3127-1287'}, 'institutions': [{'id': 'https://openalex.org/I4210146211', 'display_name': 'Utano Hospital', 'ror': 'https://ror.org/04rzagz55', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210137409', 'https://openalex.org/I4210146211']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Steven Jacobson', 'raw_affiliation_strings': ['Clinical Research Center (Dr. Nishimura), Utano National Hospital, Narutaki Ukyo-ku, Kyoto, Japan, and the Neuroimmunology Branch (Drs. McFarlin and Jacobson), National Institutes of Health, Bethesda, MD.'], 'affiliations': [{'raw_affiliation_string': 'Clinical Research Center (Dr. Nishimura), Utano National Hospital, Narutaki Ukyo-ku, Kyoto, Japan, and the Neuroimmunology Branch (Drs. McFarlin and Jacobson), National Institutes of Health, Bethesda, MD.', 'institution_ids': ['https://openalex.org/I4210146211', 'https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.684, 'has_fulltext': False, 'cited_by_count': 18, 'citation_normalized_percentile': {'value': 0.578624, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '43', 'issue': '12', 'first_page': '2621', 'last_page': '2621'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12159', 'display_name': 'T-cell and Retrovirus Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12159', 'display_name': 'T-cell and Retrovirus Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12733', 'display_name': 'Vector-Borne Animal Diseases', 'score': 0.9275, 'subfield': {'id': 'https://openalex.org/subfields/1105', 'display_name': 'Ecology, Evolution, Behavior and Systematics'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tropical-spastic-paraparesis', 'display_name': 'Tropical spastic paraparesis', 'score': 0.95272034}, {'id': 'https://openalex.org/keywords/human-t-lymphotropic-virus', 'display_name': 'Human T-lymphotropic virus', 'score': 0.8748996}, {'id': 'https://openalex.org/keywords/provirus', 'display_name': 'Provirus', 'score': 0.8560798}, {'id': 'https://openalex.org/keywords/asymptomatic-carrier', 'display_name': 'Asymptomatic carrier', 'score': 0.6489525}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.5031108}, {'id': 'https://openalex.org/keywords/sequence', 'display_name': 'Sequence (biology)', 'score': 0.46315897}, {'id': 'https://openalex.org/keywords/tissue-tropism', 'display_name': 'Tissue tropism', 'score': 0.45410782}], 'concepts': [{'id': 'https://openalex.org/C2776392238', 'wikidata': 'https://www.wikidata.org/wiki/Q1476361', 'display_name': 'Tropical spastic paraparesis', 'level': 4, 'score': 0.95272034}, {'id': 'https://openalex.org/C2776368728', 'wikidata': 'https://www.wikidata.org/wiki/Q12258832', 'display_name': 'Human T-lymphotropic virus', 'level': 4, 'score': 0.8748996}, {'id': 'https://openalex.org/C102906071', 'wikidata': 'https://www.wikidata.org/wiki/Q422467', 'display_name': 'Provirus', 'level': 4, 'score': 0.8560798}, {'id': 'https://openalex.org/C2777910003', 'wikidata': 'https://www.wikidata.org/wiki/Q1707292', 'display_name': 'Asymptomatic', 'level': 2, 'score': 0.7562964}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.74066097}, {'id': 'https://openalex.org/C2778431562', 'wikidata': 'https://www.wikidata.org/wiki/Q189308', 'display_name': 'Retrovirus', 'level': 3, 'score': 0.72384125}, {'id': 'https://openalex.org/C35693153', 'wikidata': 'https://www.wikidata.org/wiki/Q239762', 'display_name': 'Tropism', 'level': 3, 'score': 0.69657147}, {'id': 'https://openalex.org/C137916694', 'wikidata': 'https://www.wikidata.org/wiki/Q1549382', 'display_name': 'Asymptomatic carrier', 'level': 3, 'score': 0.6489525}, {'id': 'https://openalex.org/C2776238826', 'wikidata': 'https://www.wikidata.org/wiki/Q1280388', 'display_name': 'Human T-lymphotropic virus 1', 'level': 4, 'score': 0.5755533}, {'id': 'https://openalex.org/C2777604421', 'wikidata': 'https://www.wikidata.org/wiki/Q2303951', 'display_name': 'Myelopathy', 'level': 3, 'score': 0.57357043}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.5031108}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4898412}, {'id': 'https://openalex.org/C2778112365', 'wikidata': 'https://www.wikidata.org/wiki/Q3511065', 'display_name': 'Sequence (biology)', 'level': 2, 'score': 0.46315897}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.45627043}, {'id': 'https://openalex.org/C33602714', 'wikidata': 'https://www.wikidata.org/wiki/Q7809666', 'display_name': 'Tissue tropism', 'level': 4, 'score': 0.45410782}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.41986233}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3336389}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.26151198}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2390694}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.10273805}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C2780775167', 'wikidata': 'https://www.wikidata.org/wiki/Q9606', 'display_name': 'Spinal cord', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2776913467', 'wikidata': 'https://www.wikidata.org/wiki/Q7667895', 'display_name': 'T-cell leukemia', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015490', 'descriptor_name': 'HTLV-I Infections', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015493', 'descriptor_name': 'Paraparesis, Tropical Spastic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002353', 'descriptor_name': 'Carrier State', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016355', 'descriptor_name': 'Genes, pX', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015490', 'descriptor_name': 'HTLV-I Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015368', 'descriptor_name': 'Human T-lymphotropic virus 1', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D015368', 'descriptor_name': 'Human T-lymphotropic virus 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008393', 'descriptor_name': 'Marriage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015493', 'descriptor_name': 'Paraparesis, Tropical Spastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012091', 'descriptor_name': 'Repetitive Sequences, Nucleic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012689', 'descriptor_name': 'Sequence Homology, Nucleic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013602', 'descriptor_name': 'T-Lymphocytes, Cytotoxic', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013602', 'descriptor_name': 'T-Lymphocytes, Cytotoxic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.43.12.2621', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7504797', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4231131888', 'https://openalex.org/W2414306338', 'https://openalex.org/W2319301385', 'https://openalex.org/W2171787185', 'https://openalex.org/W2141242051', 'https://openalex.org/W2132110183', 'https://openalex.org/W2123272094', 'https://openalex.org/W2115842435', 'https://openalex.org/W2046564789', 'https://openalex.org/W2022490448'], 'abstract_inverted_index': {'We': [0, 55], 'amplified': [1], 'and': [2, 16, 35, 48, 62, 113], 'sequenced': [3], 'portions': [4], 'of': [5, 29, 65, 91, 139, 146], 'the': [6, 49, 60, 78, 97, 117, 134, 144], 'human': [7], 'T-lymphotropic': [8], 'virus': [9], 'type': [10], 'I': [11], '(HTLV-I)': [12], '(U3),': [13], 'pol,': [14], 'env,': [15], 'pX': [17, 99], 'provirus': [18], 'regions': [19, 58, 64, 110, 119], '(1212': [20], 'bp': [21], 'per': [22], 'person)': [23], 'from': [24, 88], 'peripheral': [25], 'blood': [26], 'lymphocytes': [27], '(PBL)': [28], 'two': [30], 'married': [31], 'couples': [32], '(case': [33], '1': [34], 'case': [36], '2).': [37], 'Both': [38], 'husbands': [39], 'are': [40, 51, 141], 'patients': [41, 93], 'with': [42], 'HTLV-I-associated': [43], 'myelopathy/tropical': [44], 'spastic': [45], 'paraparesis': [46], '(HAM/TSP),': [47], 'wives': [50], 'asymptomatic': [52, 114], 'HTLV-I': [53, 98, 109, 118, 140], 'carriers.': [54], 'selected': [56], 'these': [57, 108], 'because': [59], 'LTR': [61], 'env': [63], 'murine': [66], 'retrovirus': [67], 'models': [68], 'have': [69], 'been': [70], 'involved': [71, 142], 'in': [72, 96, 107, 143], 'determining': [73], 'tissue': [74], 'tropism.': [75], 'In': [76, 116], 'addition,': [77], 'predominant': [79], 'immunogenic': [80], 'epitope': [81], 'for': [82], 'HTLV-I-specific': [83], 'cytotoxic': [84], 'T': [85], 'cells': [86], 'obtained': [87], 'circulating': [89], 'PBL': [90], 'HAM/TSP': [92], 'was': [94, 103], 'localized': [95], 'region.': [100], 'Our': [101], 'aim': [102], 'to': [104], 'examine': [105], 'variations': [106], 'between': [111, 126], 'affected': [112], 'spouses.': [115], 'studied,': [120], 'we': [121], 'detected': [122], 'no': [123], 'sequence': [124], 'variation': [125], 'each': [127], 'couple.': [128], 'These': [129], 'data': [130], 'do': [131], 'not': [132], 'favor': [133], 'hypothesis': [135], 'that': [136], 'neurotropic': [137], 'mutants': [138], 'pathogenesis': [145], 'HAM/TSP.': [147]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1989996481', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-12T06:22:50.291894', 'created_date': '2016-06-24'}