Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1989774778', 'doi': 'https://doi.org/10.1620/tjem.218.207', 'title': 'Sequence-Based spa Typing as a Rapid Screening Method for the Areal and Nosocomial Outbreaks of MRSA', 'display_name': 'Sequence-Based spa Typing as a Rapid Screening Method for the Areal and Nosocomial Outbreaks of MRSA', 'publication_year': 2009, 'publication_date': '2009-01-01', 'ids': {'openalex': 'https://openalex.org/W1989774778', 'doi': 'https://doi.org/10.1620/tjem.218.207', 'mag': '1989774778', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19561391'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1620/tjem.218.207', 'pdf_url': 'https://www.jstage.jst.go.jp/article/tjem/218/3/218_3_207/_pdf', 'source': {'id': 'https://openalex.org/S189069745', 'display_name': 'The Tohoku Journal of Experimental Medicine', 'issn_l': '0040-8727', 'issn': ['0040-8727', '1349-3329'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313307', 'host_organization_name': 'Tohoku University', 'host_organization_lineage': ['https://openalex.org/P4310313307'], 'host_organization_lineage_names': ['Tohoku University'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jstage.jst.go.jp/article/tjem/218/3/218_3_207/_pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044526872', 'display_name': 'Munetoshi Narukawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42766147', 'display_name': 'University of Toyama', 'ror': 'https://ror.org/0445phv87', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I42766147']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Munetoshi Narukawa', 'raw_affiliation_strings': ['Department of Clinical infectious diseases, University of Toyama'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical infectious diseases, University of Toyama', 'institution_ids': ['https://openalex.org/I42766147']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090416709', 'display_name': 'Akira Yasuoka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42766147', 'display_name': 'University of Toyama', 'ror': 'https://ror.org/0445phv87', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I42766147']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akira Yasuoka', 'raw_affiliation_strings': ['Department of Clinical infectious diseases, University of Toyama'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical infectious diseases, University of Toyama', 'institution_ids': ['https://openalex.org/I42766147']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5096655039', 'display_name': 'Ryougo Note', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143192', 'display_name': 'Toyama University Hospital', 'ror': 'https://ror.org/04a2npp96', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210143192']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ryougo Note', 'raw_affiliation_strings': ['Department of Clinical Laboratory, Toyama University Hospital'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Laboratory, Toyama University Hospital', 'institution_ids': ['https://openalex.org/I4210143192']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061342454', 'display_name': 'Hisashi FUNADA', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42766147', 'display_name': 'University of Toyama', 'ror': 'https://ror.org/0445phv87', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I42766147']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hisashi Funada', 'raw_affiliation_strings': ['Department of Clinical infectious diseases, University of Toyama'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical infectious diseases, University of Toyama', 'institution_ids': ['https://openalex.org/I42766147']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.329, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.686876, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '218', 'issue': '3', 'first_page': '207', 'last_page': '213'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10195', 'display_name': 'Antimicrobial Resistance in Staphylococcus', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10195', 'display_name': 'Antimicrobial Resistance in Staphylococcus', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12167', 'display_name': 'Bacterial Identification and Susceptibility Testing', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial biofilms and quorum sensing', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/multilocus-sequence-typing', 'display_name': 'Multilocus sequence typing', 'score': 0.52275133}], 'concepts': [{'id': 'https://openalex.org/C42084846', 'wikidata': 'https://www.wikidata.org/wiki/Q855275', 'display_name': 'Pulsed-field gel electrophoresis', 'level': 4, 'score': 0.9426735}, {'id': 'https://openalex.org/C2781209916', 'wikidata': 'https://www.wikidata.org/wiki/Q3215756', 'display_name': 'Typing', 'level': 2, 'score': 0.8829487}, {'id': 'https://openalex.org/C116675565', 'wikidata': 'https://www.wikidata.org/wiki/Q3241045', 'display_name': 'Outbreak', 'level': 2, 'score': 0.7733102}, {'id': 'https://openalex.org/C2779489039', 'wikidata': 'https://www.wikidata.org/wiki/Q188121', 'display_name': 'Staphylococcus aureus', 'level': 3, 'score': 0.55654174}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.5303047}, {'id': 'https://openalex.org/C77434933', 'wikidata': 'https://www.wikidata.org/wiki/Q4043440', 'display_name': 'Multilocus sequence typing', 'level': 4, 'score': 0.52275133}, {'id': 'https://openalex.org/C2777052132', 'wikidata': 'https://www.wikidata.org/wiki/Q595158', 'display_name': 'Methicillin-resistant Staphylococcus aureus', 'level': 4, 'score': 0.49350154}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.40655637}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36874175}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.2733364}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.16841546}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.1411128}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.111815184}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.052663714}], 'mesh': [{'descriptor_ui': 'D003428', 'descriptor_name': 'Cross Infection', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004196', 'descriptor_name': 'Disease Outbreaks', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016106', 'descriptor_name': 'Methicillin Resistance', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013203', 'descriptor_name': 'Staphylococcal Infections', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D013205', 'descriptor_name': 'Staphylococcal Protein A', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D003428', 'descriptor_name': 'Cross Infection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016106', 'descriptor_name': 'Methicillin Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055624', 'descriptor_name': 'Methicillin-Resistant Staphylococcus aureus', 'qualifier_ui': 'Q000145', 'qualifier_name': 'classification', 'is_major_topic': False}, {'descriptor_ui': 'D055624', 'descriptor_name': 'Methicillin-Resistant Staphylococcus aureus', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D055624', 'descriptor_name': 'Methicillin-Resistant Staphylococcus aureus', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': False}, {'descriptor_ui': 'D055624', 'descriptor_name': 'Methicillin-Resistant Staphylococcus aureus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013203', 'descriptor_name': 'Staphylococcal Infections', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013203', 'descriptor_name': 'Staphylococcal Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013205', 'descriptor_name': 'Staphylococcal Protein A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1620/tjem.218.207', 'pdf_url': 'https://www.jstage.jst.go.jp/article/tjem/218/3/218_3_207/_pdf', 'source': {'id': 'https://openalex.org/S189069745', 'display_name': 'The Tohoku Journal of Experimental Medicine', 'issn_l': '0040-8727', 'issn': ['0040-8727', '1349-3329'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313307', 'host_organization_name': 'Tohoku University', 'host_organization_lineage': ['https://openalex.org/P4310313307'], 'host_organization_lineage_names': ['Tohoku University'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19561391', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1620/tjem.218.207', 'pdf_url': 'https://www.jstage.jst.go.jp/article/tjem/218/3/218_3_207/_pdf', 'source': {'id': 'https://openalex.org/S189069745', 'display_name': 'The Tohoku Journal of Experimental Medicine', 'issn_l': '0040-8727', 'issn': ['0040-8727', '1349-3329'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313307', 'host_organization_name': 'Tohoku University', 'host_organization_lineage': ['https://openalex.org/P4310313307'], 'host_organization_lineage_names': ['Tohoku University'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.42, 'display_name': 'Reduced inequalities', 'id': 'https://metadata.un.org/sdg/10'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W148535273', 'https://openalex.org/W1601256941', 'https://openalex.org/W1846007132', 'https://openalex.org/W1914701394', 'https://openalex.org/W1955612312', 'https://openalex.org/W1995050956', 'https://openalex.org/W2005853912', 'https://openalex.org/W2046427067', 'https://openalex.org/W2048231745', 'https://openalex.org/W2050578596', 'https://openalex.org/W2052143101', 'https://openalex.org/W2081802739', 'https://openalex.org/W2092810704', 'https://openalex.org/W2101593135', 'https://openalex.org/W2103123638', 'https://openalex.org/W2103880491', 'https://openalex.org/W2104411795', 'https://openalex.org/W2107030752', 'https://openalex.org/W2112821394', 'https://openalex.org/W2120443139', 'https://openalex.org/W2124000790', 'https://openalex.org/W2124105350', 'https://openalex.org/W2125211897', 'https://openalex.org/W2134366416', 'https://openalex.org/W2154239309', 'https://openalex.org/W2165374028', 'https://openalex.org/W2170205901', 'https://openalex.org/W2170742758'], 'related_works': ['https://openalex.org/W2771955576', 'https://openalex.org/W2147103517', 'https://openalex.org/W2144609242', 'https://openalex.org/W2141078759', 'https://openalex.org/W2119730621', 'https://openalex.org/W2109474249', 'https://openalex.org/W2104019857', 'https://openalex.org/W2057174194', 'https://openalex.org/W1995968405', 'https://openalex.org/W1847473553'], 'abstract_inverted_index': {'Methicillin-resistant': [0], 'Staphylococcus': [1, 74], 'aureus': [2, 75], '(MRSA)': [3], 'is': [4, 28, 41, 60, 85, 106, 218, 240], 'the': [5, 20, 44, 82, 96, 154, 165, 186, 197, 233], 'leading': [6], 'cause': [7], 'of': [8, 25, 52, 73, 104, 130], 'nosocomial': [9, 34, 109, 118, 142], 'infection': [10, 35], 'and': [11, 22, 33, 63, 78, 92, 112, 125, 174, 217, 221, 244], 'MRSA': [12, 26, 49, 105, 238], 'outbreaks': [13], 'have': [14], 'become': [15], 'a': [16, 69, 140, 219], 'major': [17], 'problem.': [18], 'Therefore,': [19], 'rapid': [21, 220, 234], 'accurate': [23], 'typing': [24, 103, 138, 152, 176, 211, 228], 'isolates': [27, 120, 127], 'important': [29], 'for': [30, 48, 108], 'epidemiological': [31, 113], 'surveys': [32], 'control.': [36], 'Pulsed-field': [37], 'gel': [38], 'electrophoresis': [39], '(PFGE)': [40], 'considered': [42], 'as': [43, 232], 'gold': [45], 'standard': [46], 'technique': [47], 'typing,': [50], 'because': [51], 'its': [53, 58], 'high': [54], 'discriminatory': [55], 'power,': [56], 'but': [57, 158], 'procedure': [59], 'rather': [61], 'complicated': [62], 'time-consuming.': [64], 'The': [65, 225], 'spa': [66, 83, 102, 137, 151, 175, 187, 210, 227], 'gene': [67, 84, 188], 'encodes': [68], 'cell': [70], 'wall': [71], 'component': [72], 'protein': [76], 'A,': [77], 'exhibits': [79], 'polymorphism.': [80], 'Sequencing': [81], 'expected': [86], 'superior': [87], 'to': [88, 147, 184, 195, 215], 'PFGE': [89, 135, 159, 169], 'in': [90, 189, 242], 'speed': [91], 'data': [93], 'interpretation.': [94], 'In': [95, 207], 'present': [97], 'study,': [98], 'we': [99, 181], 'evaluated': [100], 'whether': [101], 'useful': [107], 'outbreak': [110, 119, 239], 'analysis': [111], 'investigations.': [114], 'We': [115], 'analyzed': [116], '19': [117], 'from': [121, 128, 193], '4': [122], 'separate': [123], 'hospitals': [124], '26': [126], 'outpatients': [129], 'Toyama': [131], 'University': [132], 'Hospital.': [133], 'Either': [134], 'or': [136], 'revealed': [139], 'single': [141], 'strain': [143], 'that': [144], 'appears': [145], 'unique': [146], 'each': [148], 'hospital.': [149], 'Indeed,': [150], 'confirmed': [153], 'four': [155], 'different': [156, 172], 'strains,': [157], 'demonstrated': [160], 'only': [161], '3': [162], 'strains.': [163], 'With': [164], 'total': [166], '45': [167], 'isolates,': [168], 'showed': [170, 177], '16': [171], 'patterns': [173], '12': [178], 'patterns.': [179], 'Moreover,': [180], 'were': [182], 'able': [183], 'analyze': [185], 'about': [190, 202], '2': [191], 'days,': [192], 'sampling': [194], 'obtaining': [196], 'results,': [198], 'whereas': [199], 'it': [200], 'took': [201], '7': [203], 'days': [204], 'with': [205], 'PFGE.': [206], 'conclusion,': [208], 'sequence-based': [209, 226], 'shows': [212], 'comparable': [213], 'sensitivities': [214], 'PFGE,': [216], 'easy': [222], 'handling': [223], 'method.': [224], 'can': [229], 'be': [230], 'used': [231], 'screening': [235], 'test': [236], 'when': [237], 'suspected': [241], 'areas': [243], 'hospitals.': [245]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1989774778', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-24T14:53:04.781806', 'created_date': '2016-06-24'}