Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1989552101', 'doi': 'https://doi.org/10.1016/j.jsbmb.2014.11.026', 'title': 'The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1)', 'display_name': 'The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1)', 'publication_year': 2014, 'publication_date': '2014-12-05', 'ids': {'openalex': 'https://openalex.org/W1989552101', 'doi': 'https://doi.org/10.1016/j.jsbmb.2014.11.026', 'mag': '1989552101', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25482340', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4456341'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.jsbmb.2014.11.026', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168421034', 'display_name': 'The Journal of Steroid Biochemistry and Molecular Biology', 'issn_l': '0960-0760', 'issn': ['0960-0760', '1879-1220'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc4456341?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084225542', 'display_name': 'Francis K. Yoshimoto', 'orcid': 'https://orcid.org/0000-0002-2308-2999'}, 'institutions': [{'id': 'https://openalex.org/I200719446', 'display_name': 'Vanderbilt University', 'ror': 'https://ror.org/02vm5rt34', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I200719446']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Francis K. Yoshimoto', 'raw_affiliation_strings': ['Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine , Nashville, Tennessee 37232-0146, United States.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine , Nashville, Tennessee 37232-0146, United States.', 'institution_ids': ['https://openalex.org/I200719446']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5055037280', 'display_name': 'Richard J. Auchus', 'orcid': 'https://orcid.org/0000-0001-6815-6181'}, 'institutions': [{'id': 'https://openalex.org/I27837315', 'display_name': 'University of Michigan–Ann Arbor', 'ror': 'https://ror.org/00jmfr291', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I27837315']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard J. Auchus', 'raw_affiliation_strings': ['Division of Metabolism, Diabetes, and Endocrinology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48019, United States.'], 'affiliations': [{'raw_affiliation_string': 'Division of Metabolism, Diabetes, and Endocrinology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48019, United States.', 'institution_ids': ['https://openalex.org/I27837315']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3710, 'currency': 'USD', 'value_usd': 3710, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.694, 'has_fulltext': False, 'cited_by_count': 91, 'citation_normalized_percentile': {'value': 0.702564, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '151', 'issue': None, 'first_page': '52', 'last_page': '65'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10375', 'display_name': 'Pharmacogenetics and Drug Metabolism', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10375', 'display_name': 'Pharmacogenetics and Drug Metabolism', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11839', 'display_name': 'Hormonal Regulation and Hypertension', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cyp17a1', 'display_name': 'CYP17A1', 'score': 0.99253875}], 'concepts': [{'id': 'https://openalex.org/C142716871', 'wikidata': 'https://www.wikidata.org/wiki/Q408305', 'display_name': 'CYP17A1', 'level': 3, 'score': 0.99253875}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.604626}, {'id': 'https://openalex.org/C2780902042', 'wikidata': 'https://www.wikidata.org/wiki/Q177911', 'display_name': 'Steroid', 'level': 3, 'score': 0.57927024}, {'id': 'https://openalex.org/C526171541', 'wikidata': 'https://www.wikidata.org/wiki/Q407693', 'display_name': 'Cytochrome P450', 'level': 3, 'score': 0.5538213}, {'id': 'https://openalex.org/C2777911890', 'wikidata': 'https://www.wikidata.org/wiki/Q62614', 'display_name': 'Androgen', 'level': 3, 'score': 0.51025534}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.40155327}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.33131117}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.07208952}], 'mesh': [{'descriptor_ui': 'D013254', 'descriptor_name': 'Steroid 17-alpha-Hydroxylase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002384', 'descriptor_name': 'Catalysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013254', 'descriptor_name': 'Steroid 17-alpha-Hydroxylase', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013254', 'descriptor_name': 'Steroid 17-alpha-Hydroxylase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013254', 'descriptor_name': 'Steroid 17-alpha-Hydroxylase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013256', 'descriptor_name': 'Steroids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013256', 'descriptor_name': 'Steroids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.jsbmb.2014.11.026', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168421034', 'display_name': 'The Journal of Steroid Biochemistry and Molecular Biology', 'issn_l': '0960-0760', 'issn': ['0960-0760', '1879-1220'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4456341', 'pdf_url': 'https://europepmc.org/articles/pmc4456341?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456341', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25482340', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4456341', 'pdf_url': 'https://europepmc.org/articles/pmc4456341?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 55, 'referenced_works': ['https://openalex.org/W1522709944', 'https://openalex.org/W1527041796', 'https://openalex.org/W1534713573', 'https://openalex.org/W1654366416', 'https://openalex.org/W1891933871', 'https://openalex.org/W1907523994', 'https://openalex.org/W1965969235', 'https://openalex.org/W1967240005', 'https://openalex.org/W1968400590', 'https://openalex.org/W1968973920', 'https://openalex.org/W1980255186', 'https://openalex.org/W1986479120', 'https://openalex.org/W1993563154', 'https://openalex.org/W1994012595', 'https://openalex.org/W1996451304', 'https://openalex.org/W2004011863', 'https://openalex.org/W2010143253', 'https://openalex.org/W2014458169', 'https://openalex.org/W2017515394', 'https://openalex.org/W2020954599', 'https://openalex.org/W2024092408', 'https://openalex.org/W2025409217', 'https://openalex.org/W2025958452', 'https://openalex.org/W2027103264', 'https://openalex.org/W2027105842', 'https://openalex.org/W2032987473', 'https://openalex.org/W2036268251', 'https://openalex.org/W2038816757', 'https://openalex.org/W2045294456', 'https://openalex.org/W2046580571', 'https://openalex.org/W2046984971', 'https://openalex.org/W2047790450', 'https://openalex.org/W2048557976', 'https://openalex.org/W2052227787', 'https://openalex.org/W2053012453', 'https://openalex.org/W2053688030', 'https://openalex.org/W2057727568', 'https://openalex.org/W2058275487', 'https://openalex.org/W2061547898', 'https://openalex.org/W2062683863', 'https://openalex.org/W2064457967', 'https://openalex.org/W2065675762', 'https://openalex.org/W2071758483', 'https://openalex.org/W2073110497', 'https://openalex.org/W2079050871', 'https://openalex.org/W2103662350', 'https://openalex.org/W2106195907', 'https://openalex.org/W2112100343', 'https://openalex.org/W2126733133', 'https://openalex.org/W2134798697', 'https://openalex.org/W2141052359', 'https://openalex.org/W2143669794', 'https://openalex.org/W2149048157', 'https://openalex.org/W2162116513', 'https://openalex.org/W4323517721'], 'related_works': ['https://openalex.org/W4383262944', 'https://openalex.org/W3092177084', 'https://openalex.org/W2461552319', 'https://openalex.org/W2365048306', 'https://openalex.org/W2155404066', 'https://openalex.org/W2142312240', 'https://openalex.org/W2009067244', 'https://openalex.org/W1990002146', 'https://openalex.org/W1574903480', 'https://openalex.org/W1028076256'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1989552101', 'counts_by_year': [{'year': 2024, 'cited_by_count': 11}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 12}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-12-09T14:24:29.697737', 'created_date': '2016-06-24'}