Publication Information

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[1254], 'December': [1255], '1988': [1256], 'https://doi.org/10.1111/j.1749-6632.1988.tb21614.xCitations:': [1257], '7': [1258, 1553], 'a': [1259, 1295, 1301, 1306, 1314, 1370, 1385, 1601, 2246, 2446], 'This': [1260], 'work': [1261], 'was': [1262, 1305], 'supported': [1263, 1293], 'grants': [1265, 1274], 'from': [1266, 2245], 'organization': [1271, 1665, 1752], 'NIH': [1273], 'AI-20047': [1275], 'CA-40427.': [1277], 'P.F.': [1278], 'is': [1279, 1292, 1300, 1313, 2035, 2104], 'an': [1280], 'EMBO': [1281, 1515, 1549, 1608, 1648, 1765, 2225, 2453, 2504], 'fellow,': [1282], 'B.A.M.,': [1283], 'G.R.,': [1284], 'R.P.': [1286], 'are': [1287], 'Leukemia': [1288], 'Society': [1289], 'Fellows,': [1290], 'P.R.': [1291], 'Physician': [1296], 'Scientist': [1297], 'award,': [1298], 'S.M.': [1299], 'Pfizer': [1302], 'Fellow,': [1303, 1310], 'J.B.': [1304], 'Damon': [1307], 'Runyon-Walter': [1308], 'Winchell': [1309], 'A.F.': [1312], 'Jane': [1315], 'Coffin': [1316], 'Childs': [1317], 'Fellow.': [1318], 'AboutPDF': [1319], 'ToolsRequest': [1320], 'permissionExport': [1321], 'citationAdd': [1322], 'to': [1323, 1345, 1368, 2502], 'favoritesTrack': [1324], 'citation': [1325], 'ShareShare': [1326], 'Give': [1327], 'accessShare': [1328, 1331], 'full': [1329], 'text': [1330], 'full-text': [1332, 1347, 1371], 'accessPlease': [1333], 'review': [1334], 'our': [1335], 'Terms': [1336, 1359], 'Conditions': [1338, 1361], 'Use': [1340], 'check': [1342], 'box': [1343], 'below': [1344, 1367], 'share': [1346, 1369], 'version': [1348, 1372], 'article.I': [1350], 'have': [1351], 'read': [1352], 'accept': [1354], 'Wiley': [1356], 'Online': [1357], 'Library': [1358], 'UseShareable': [1363], 'LinkUse': [1364], 'link': [1366], 'article': [1375], 'with': [1376, 2108, 2142, 2248, 2494], 'your': [1377], 'friends': [1378], 'colleagues.': [1380], 'Learn': [1381], 'more.Copy': [1382], 'URL': [1383], 'Share': [1384], 'linkShare': [1386], 'onEmailFacebookTwitterLinkedInRedditWechat': [1387], 'References': [1388], 'Tonegawa,': [1390], 'S.': [1391, 1499, 1734, 1774, 2205, 2281, 2364, 2425, 2459, 2483], '1983.': [1392], 'Somatic': [1393], 'generation': [1394], 'antibody': [1396, 1417, 2013], 'diversity.': [1397], 'Nature': [1398, 1823, 2373], '302:': [1399], '575.': [1400], '2': [1401], 'Alt,': [1402, 1451, 1482, 2230, 2309], 'F.': [1403, 1452, 1483, 1529, 1586, 1727, 1747, 1833, 1868, 1905, 1941, 1966, 1984, 2089, 2181, 2208, 2231, 2310, 2344, 2369, 2389, 2392, 2431, 2461, 2518], 'W.,': [1404, 1453, 1484, 2075, 2311], 'T.': [1405, 1454, 1573, 1776, 1829, 1835, 1840, 1864, 1870, 1875, 2086, 2156, 2340, 2354], 'K.': [1406, 1455, 1487, 1590, 1806, 2157, 2422], 'Blackwell': [1407], '&': [1408, 1429, 1464, 1501, 1528, 1572, 1589, 1616, 1634, 1658, 1699, 1726, 1746, 1778, 1812, 1839, 1874, 1904, 1940, 1965, 1983, 2004, 2055, 2094, 2126, 2180, 2207, 2233, 2280, 2318, 2342, 2368, 2391, 2430, 2460, 2482, 2517], 'G.': [1409, 1425, 1462, 1465, 1485, 1808, 1934, 2118, 2120, 2159, 2162, 2177, 2359, 2417, 2426], 'D.': [1410, 1458, 1466, 1502, 1584, 1810, 1935, 2023, 2178, 2234, 2319, 2360], 'Yancopoulos': [1411, 1467], '1987.': [1412, 1532, 1557, 1593, 1619, 1637, 1908, 1944, 2130, 2284], 'Development': [1413], 'primary': [1416, 1994], 'repertoire.': [1418, 1953], 'Science': [1419, 2018], '288:': [1420], '1079–1087.': [1421], '3': [1422], 'Kronenberg,': [1423], 'M.,': [1424, 1521, 1828, 1863, 2119], 'Siu,': [1426], 'L.': [1427, 1526, 1700, 1742, 2171, 2315, 2387], 'Hood': [1428, 1701], 'N.': [1430, 1495, 2084, 2428], 'Shastri': [1431], '1986.': [1432, 1468, 1702, 1842, 1877, 2026, 2058, 2098, 2211, 2372, 2434, 2485], 'molecular': [1434, 2061], 'genetics': [1435], 'T-cell': [1438, 1442], 'antigen': [1439, 1443, 2101], 'receptor': [1440, 2102, 2401], 'recognition,': [1444], 'Ann.': [1445, 1624], 'Rev.': [1446, 1478, 1625, 2070], 'Immunol.,': [1447], '4:': [1448], '529.': [1449, 1860], '4': [1450], 'Blackwell,': [1456, 1488, 2158, 2353], 'R.': [1457, 1493, 1659, 1689, 1736, 1804, 1906, 2081, 2091, 2127, 2174, 2338, 2419, 2513, 2515], 'DE': [1459], 'Pinho,': [1460], 'M.': [1461, 1489, 1655, 1725, 2051, 2095, 2123, 2160, 2203, 2269, 2316, 2356], 'Reth': [1463], 'Regulation': [1469, 1671], 'genome': [1471], 'rearrangement': [1472, 1506, 1537, 2397, 2437], 'events': [1473, 2438], 'during': [1474, 2217], 'lymphocyte': [1475, 1563], 'differentiation.': [1476], 'Immunol.': [1477, 1566, 1626, 1957, 2045, 2069, 2149], '89:': [1479], '5.': [1480], '5': [1481], 'Yancopoulos,': [1486, 1936, 1961, 2179, 2361, 2416], 'Boss,': [1490], 'E.': [1491, 1522, 1615, 2366], 'Thomas,': [1492], 'Coffman,': [1494], 'Rosenberg,': [1496, 2085], 'C.': [1497, 1697, 1738, 1744, 1899, 1937, 2056, 2121, 2343], 'Wood,': [1498], 'Tonegawa': [1500], 'Baltimore': [1503, 2235, 2320], '1984.': [1504, 1575, 1661], 'Ordered': [1505], 'Ig': [1508, 1639, 2528], 'heavy': [1509, 1547, 1595, 1704, 1854, 1889, 1949, 2240, 2489, 2498, 2534], 'chain': [1510, 1596, 1705, 1950, 2241, 2490, 2499, 2535], 'variable': [1511, 1706, 1847, 1882, 1916, 1951, 2402], 'region': [1512, 1598, 1707, 1848, 1883, 1917, 2403], 'gene': [1513, 1536, 1708, 1918, 1952, 1973, 1991, 2223, 2242, 2404], 'segments.': [1514, 2224], 'J.': [1516, 1550, 1609, 1617, 1649, 1770, 1813, 1856, 1891, 1932, 1982, 2044, 2077, 2088, 2096, 2124, 2166, 2226, 2264, 2265, 2271, 2273, 2275, 2282, 2454, 2481, 2505], '3:': [1517], '1209–219.': [1518], '6': [1519], 'Reth,': [1520, 2202], 'Petrac,': [1523], 'P.': [1524, 1555, 1779, 1901, 2092, 2169, 2276, 2278, 2511], 'Wiese,': [1525], 'Lobel': [1527], 'Alt': [1531, 1588, 1748, 1943, 1967, 1985, 2183, 2210, 2371, 2393, 2433, 2463, 2519], 'Activation': [1533], 'VK': [1535], 'in': [1538, 1604, 1643, 1711, 1922, 1993, 2015, 2038, 2067, 2106, 2134, 2439], 'pre-B': [1539, 1606, 2218, 2440], 'cells': [1540, 2140], 'follows': [1541], 'expression': [1543, 2330, 2467, 2525], 'membrane-bound': [1545], 'immunoglobulin': [1546, 1786, 1820, 1853, 1888, 1948, 2194, 2239, 2332, 2488], 'chains.': [1548], '6:': [1551, 1610, 1650], '3299–3305.': [1552], 'Kincade,': [1554], 'Experimental': [1558], 'models': [1559], 'understanding': [1561], 'B': [1562, 1646], 'formation.': [1564], 'Adv.': [1565], '41:': [1567], '181.': [1568], '8': [1569], 'Shimizu,': [1570], 'A.': [1571, 1635, 1656, 1938, 2005, 2079, 2082, 2128, 2163, 2165, 2175, 2314, 2381, 2383, 2420, 2423], 'Honjo': [1574, 1841, 1876], 'Immunoglobulin': [1576, 1594], 'class': [1577, 1640, 2451, 2491, 2536], 'switching.': [1578, 2503, 2537], 'Cell': [1579, 1720, 1798, 2113, 2198, 2475, 2538], '36:': [1580], '801–803.': [1581], '9': [1582], 'Ott,': [1583], 'E.,': [1585, 1631], 'B.': [1591, 1814, 1963, 2053, 2154, 2172, 2379], 'Marcu': [1592], 'switch': [1597, 1641, 2492], 'recombination': [1599, 1642], 'within': [1600], 'retroviral': [1602], 'vector': [1603], 'murine': [1605, 1645, 2144], 'cells.': [1607, 1647], '577.': [1611], '10': [1612], 'Paul,': [1613], 'Ohara': [1618], 'B-cell': [1620, 2041, 2132], 'stimulatory': [1621], 'factor-l/interleukin': [1622], '41.': [1623], '5:': [1627, 2227, 2455, 2506], '429–459.': [1628], '11': [1629], 'Winter,': [1630], 'U.': [1632, 1740, 1772], 'Krawinkel': [1633], 'Radbruch': [1636], 'Directed': [1638], 'activated': [1644], '1663.': [1651], '12': [1652], 'Brodeur,': [1653], 'P.,': [1654, 2378], 'Thompson': [1657], 'Riblett': [1660], 'content': [1663], 'mouse': [1667, 1714], 'IgH-V': [1668], 'families.': [1669], 'In': [1670, 1729, 1997, 2334, 2413], 'Immune': [1674, 2548], 'System,': [1675], 'UCLA': [1676], 'Symposia': [1677], 'on': [1678], 'Molecular': [1679], 'Cellular': [1681], 'Biology,': [1682], 'Series,': [1684], 'Vol.': [1685], '18:': [1686], '445.': [1687], 'Alan': [1688], 'Liss,': [1690], '.': [1693, 2351], '13': [1694], 'Livant,': [1695], 'D.,': [1696, 1803, 2418], 'Blatt': [1698], 'One': [1703], 'segment': [1709], 'subfamily': [1710], 'BALB/c': [1713], 'contains': [1715], '500-1000': [1716], 'or': [1717], 'members.': [1719], '47:': [1721], '461.': [1722], '14': [1723, 2296], 'Morrow,': [1724], 'Alt.': [1728], 'preparation.': [1730, 1998, 2414], '15': [1731], 'Berman,': [1732, 1933, 1981], 'J.,': [1733], 'Mellis,': [1735], 'Pollock,': [1737, 2514], 'Smith,': [1739], 'Surti,': [1741], 'Chess,': [1743], 'Cantor': [1745], '1988.': [1749, 1968, 2184, 2464, 2520], 'Structure': [1750, 1782, 2465], 'human': [1755, 1785, 1852, 1887, 1989], 'VH': [1756, 1763, 1821, 1972, 1990, 2442], 'locus:': [1757, 1788], 'Linkage': [1758], 'CH': [1761], 'regions.': [1764], '7:': [1766], '727–738.': [1767], '16': [1768], 'Ravetch,': [1769], 'V.,': [1771], 'Siebenlist,': [1773], 'Korsmeyer,': [1775], 'Waldmann': [1777], 'Leder': [1780], '1981.': [1781, 1816], 'μ': [1787], 'Characterization': [1789], 'embryonic': [1791], 'rearranged': [1793, 1921], 'J': [1794, 1975], 'D': [1796], 'genes.': [1797, 1822, 2333], '27:': [1799], '583.': [1800], '17': [1801], 'Givol,': [1802], 'Zakut,': [1805], 'Effron,': [1807], 'Rechavi,': [1809], 'Ram': [1811], 'Cohen': [1815], 'Diversity': [1817], 'germline': [1819, 2409, 2469, 2497], '292:': [1824], '426.': [1825], '18': [1826, 2298], 'Kodaira,': [1827, 1862], 'Kinashi,': [1830, 1865], 'I.': [1831, 1866, 2002, 2076], 'Umemura,': [1832, 1867], 'Matsuda,': [1834, 1869], 'Noma,': [1836, 1871], 'Y.': [1837, 1872], 'Oono': [1838], 'Organization': [1843, 1878], 'evolution': [1845, 1880], 'genes': [1849, 1884, 2065, 2103, 2500], 'chain.': [1855, 1890], 'Mol.': [1857, 1892, 2474], 'Biol.': [1858, 1893, 2476], '190:': [1859, 1894], '19': [1861], 'Ono': [1873], '529–541.': [1895], '20': [1896], 'Shen,': [1897], 'A.,': [1898, 2155, 2263], 'Humphries,': [1900], 'Tucker': [1903], 'Blattner': [1907], 'Proc.': [1909, 2254, 2301], 'Natl.': [1910, 2255, 2302], 'Acad.': [1911, 2256, 2303], 'Sci.': [1912, 2257, 2304], 'USA.': [1913], 'Human': [1914], 'heavy-chain': [1915], 'family': [1919], 'non-randomly': [1920], 'familial': [1923], 'chronic': [1924], 'lymphocytic': [1925], 'leukemia.': [1926], '84:': [1927, 2306], '8563–8567.': [1928], '21': [1929], 'Malynn,': [1930, 2153], 'B.,': [1931], 'Bona': [1939, 2057], 'Expression': [1945], 'Curr.': [1954], 'Top.': [1955], 'Microbiol.': [1956], '135:': [1958], '75–94.': [1959], '22': [1960], 'G.,': [1962, 2204], 'Malynn': [1964], 'Development-stage': [1969], 'strain-specific': [1971], 'repertoires.': [1974, 2042], 'Exp.': [1976], 'Med.': [1977], '168:': [1978], '417–435.': [1979], '23': [1980], 'Biased': [1986], 'utilization': [1987], 'segments': [1992, 2405], 'differentiation': [1995], 'organs.': [1996], '24': [1999], 'Rajewsky,': [2000], 'K.,': [2001, 2355], 'Forster,': [2003], 'Cumano': [2006], 'Evolutionary': [2007], 'somatic': [2009], 'selection': [2010], 'repertoire': [2014], 'mouse.': [2017], '238:': [2019], '1088–1094.': [2020], '25': [2021], 'Holmberg,': [2022], 'et': [2024], 'al.': [2025], 'high': [2028], 'idiotypic': [2029], 'connectivity': [2030], '"natural"': [2032], 'newborn': [2033], 'antibodies': [2034], 'not': [2036], 'found': [2037], 'adult': [2039], 'mitogen-reactive': [2040], 'Eur.': [2043], '16:': [2046], '82.': [2047], '26': [2048], 'Painter,': [2049], 'C.,': [2050], 'Monestier,': [2052], 'Bonin': [2054], 'Functional': [2059], 'studies': [2062], 'V': [2064], 'expressed': [2066], 'autoantibodies.': [2068], '94:': [2071], '75–98.': [2072], '27': [2073], 'Schuler,': [2074, 2080], 'Weiler,': [2078], 'Phillips,': [2083, 2176], 'Mak,': [2087], 'Kearney,': [2090], 'Perry': [2093], 'Bosma': [2097, 2125], 'Rearrangement': [2099], 'defective': [2105], 'mice': [2107], 'severe': [2109], 'combined': [2110], 'immune': [2111], 'deficiency.': [2112], '46:': [2114], '963–972.': [2115], '28': [2116], 'Fulop,': [2117, 2161], 'Bosma,': [2122], 'Phillips': [2129], 'Early': [2131], 'precursors': [2133], 'Scid': [2135, 2186], 'mice.': [2136, 2412], 'Normal': [2137], 'number': [2138], 'transformable': [2141], 'Abelson': [2143], 'leukemia': [2145], 'virus': [2146], '(A-MuLv).': [2147], 'Cell.': [2148], '113:': [2150], '192–201.': [2151], '29': [2152], 'Rathbun,': [2164], 'Furley,': [2168, 2382], 'Ferrier,': [2170, 2377], 'Heinke,': [2173], 'defect': [2187], 'affects': [2188], 'final': [2190], 'step': [2191], 'VDJ': [2195], 'recombinase': [2196], 'mechanism.': [2197], '54:': [2199], '453–460.': [2200], '30': [2201], 'Jackson': [2206], 'VHDJH': [2212], 'formation': [2213], 'DJH': [2215, 2443], 'replacement': [2216, 2444], 'differentiation:': [2219], 'Non-random': [2220], 'usage': [2221], '2131.': [2228], '31': [2229], '1982.': [2236], 'Joining': [2237], 'segments,': [2243], 'implications': [2244], 'chromosome': [2247], 'evidence': [2249], 'three': [2251], 'D-JH': [2252], 'fusions,': [2253], 'USA': [2258, 2305], '79:': [2259], '4118.': [2260], '32': [2261], 'Bakhshi,': [2262], 'Wright,': [2266], 'Graninger,': [2268], 'Seto,': [2270], 'Owens,': [2272], 'Cossman,': [2274], 'Jensen,': [2277], 'Goldman': [2279], 'Korsmeyer': [2283], 'Mechanism': [2285], 't(14;18)': [2288], 'chromosomal': [2289], 'translocation:': [2290], 'Structural': [2291], 'analysis': [2292], 'both': [2294], 'derivative': [2295], 'reciprocal': [2299], 'partners.': [2300], '2396–2400.': [2307], '33': [2308], 'V.': [2312], 'Enea,': [2313], 'Bothwell': [2317], '1979.': [2321], 'Probes': [2322], 'specific': [2324], 'mRNAs': [2325], 'subtractive': [2327], 'hybridization;': [2328], 'anomalous': [2329], 'Eukaryotic': [2335], 'Regulation.': [2337], 'Axel,': [2339], 'Maniatis,': [2341], 'Fox,': [2345], 'Eds.': [2346], 'Academic': [2347], 'Press,': [2348], '34': [2352], 'Moore,': [2358], 'H.': [2362, 2385], 'Suh,': [2363, 2386], 'Lutzker,': [2365, 2427, 2458, 2509], 'Selsing': [2367], '324:': [2374], '585–589.': [2375], '35': [2376], 'Krippl,': [2380], 'Winoto,': [2384], 'Hood,': [2388], 'Costantini,': [2390], 'Tissue': [2394], 'lineage-specific': [2396], 'T': [2399], 'cell': [2400], 'introduced': [2406], 'into': [2407], 'transgenic': [2411], '36': [2415], 'Depinho,': [2421], 'Zimmerman,': [2424], 'Rosenberg': [2429], 'Secondary': [2435], 'genomic': [2436], 'cells:': [2441], 'LINE-1': [2447], 'sequence': [2448], 'directed': [2450, 2533], 'switching,': [2452], '3259.': [2456], '37': [2457], 'gamma': [2470], '2b': [2471], 'constant': [2472], 'region.': [2473], '8:': [2477], '1849–1852.': [2478], '38': [2479], 'Stavnezer-Nordgren,': [2480], 'Sirlin': [2484], 'Specificity': [2486], 'correlates': [2493], 'activity': [2495], 'prior': [2501], '95.': [2507], '39': [2508], 'S.,': [2510], 'Rothman,': [2512], 'Coffman': [2516], 'Mitogen-': [2521], 'IL-4': [2523], 'regulated': [2524], 'germ-line': [2527], 'γ2b': [2529], 'transcripts:': [2530], 'Evidence': [2531], '53:': [2539], '177–184.': [2540], 'Citing': [2541], 'Literature': [2542], 'Volume546,': [2543], 'Issue1Molecular': [2544], 'Basis': [2545], 'ResponseDecember': [2549], '1988Pages': [2550], 'ReferencesRelatedInformation': [2552]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1989136364', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-12T16:31:51.590687', 'created_date': '2016-06-24'}