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'referenced_works': ['https://openalex.org/W2004193659', 'https://openalex.org/W2005403824', 'https://openalex.org/W2063234550', 'https://openalex.org/W2077104137', 'https://openalex.org/W2110031951', 'https://openalex.org/W2127744024', 'https://openalex.org/W2210000121', 'https://openalex.org/W2331066142', 'https://openalex.org/W2518272452', 'https://openalex.org/W432655636'], 'related_works': ['https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W2026391790', 'https://openalex.org/W1986764834', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'Wistar系ラットにTrp-P-1を': [0], '750,': [1], '1,500': [2], '及び': [3, 16], '2,500': [4], 'μg': [5, 12, 15, 18, 23, 26], '経口投与し,糞便・尿のTrp-P-1をHPLC及びサルモネラを用いたAmes法により,更に排泄物中の代謝物をTLC分画により調べた.糞便からのTrp-P-1抽出にはブルーレーヨンを,尿からの抽出にはクロロホルムを用い,両抽出法による添加回収率は,糞便では': [6], '85.9±3.9%,': [7], '尿では': [8], '91.3±3.7%': [9], 'であった.糞便・尿抽出物のTLC分画物の変異原性を調べたところ,糞便抽出物ではTrp-P-1以外に変異原性を有する画分が2つ認められたが,尿抽出物では認められなかった.Trp-P-1': [10], '750': [11, 25], '投与群の糞便・尿のTrp-P-1量は,それぞれ': [13], '81.6±7.1': [14], '28.7±4.9': [17], 'で,投与量の': [19], '10.8±0.9%': [20], 'が糞便に,3.8±0.7%': [21], 'が尿中に排泄され,変異原性試験においても類似する結果が得られた.1,500': [22], '投与群の糞便・尿中のTrp-P-1量及び変異原性は': [24], '投与群に比べ有意に高い値を示した.': [27]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1989043854', 'counts_by_year': [], 'updated_date': '2024-08-15T12:08:52.977671', 'created_date': '2016-06-24'}