Title: Germ cell function and hormonal status in patients with testicular cancer
Abstract: CancerVolume 64, Issue 4 p. 956-961 ArticleFree Access Germ cell function and hormonal status in patients with testicular cancer Peter Vejby Hansen MD, Corresponding Author Peter Vejby Hansen MD Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkDanish Cancer Society, Department of Experimental Clinical Oncology, Nørrebrogade 44, DK-8000 Aarhus C, Denmark===Search for more papers by this authorHenrik Trykker MD, Henrik Trykker MD Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkSearch for more papers by this authorJørn Andersen MD, Jørn Andersen MD Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkSearch for more papers by this authorPoul Erik Helkjær MD, Poul Erik Helkjær MD Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkSearch for more papers by this author Peter Vejby Hansen MD, Corresponding Author Peter Vejby Hansen MD Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkDanish Cancer Society, Department of Experimental Clinical Oncology, Nørrebrogade 44, DK-8000 Aarhus C, Denmark===Search for more papers by this authorHenrik Trykker MD, Henrik Trykker MD Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkSearch for more papers by this authorJørn Andersen MD, Jørn Andersen MD Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkSearch for more papers by this authorPoul Erik Helkjær MD, Poul Erik Helkjær MD Departments of Oncology and Clinical Chemistry, Aalborg Municipal Hospital, Aalborg, DenmarkSearch for more papers by this author First published: 15 August 1989 https://doi.org/10.1002/1097-0142(19890815)64:4<956::AID-CNCR2820640431>3.0.CO;2-3Citations: 65AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Sperm counts, serum gonadotropins, and androgen levels were investigated in 39 seminoma patients and 58 patients with a nonseminomatous germ cell tumor of the testis after unilateral orchiectomy. In 58% of the patients, the total sperm count was below the lower reference value (80 million). A multiregression analysis demonstrated a correlation between a decreased total sperm count and the following three explanatory variables: (1) an elevated serum alpha-fetoprotein (AFP), (2) a history of chryptorchidism, or (3) a seminomatous tumor. In 42% of the patients, the sperm concentration and the sperm motility met criteria considered sufficient for cryopreservation. Serum follicle-stimulating hormone (FSH) was elevated in 33% of the patients. Androgens (serum testosterone [T] or urine 17-oxy-steroids [17-OS]) were subnormal in 5% of the patients, whereas serum luteinizing hormone (LH) was elevated in 14% of the patients without human chorionic gonadotropin β-subunit (β-HCG) in serum. Citing Literature Volume64, Issue415 August 1989Pages 956-961 ReferencesRelatedInformation