Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1988597344', 'doi': 'https://doi.org/10.1016/j.bbrc.2006.04.157', 'title': 'Activity-dependent regulation of β-catenin via ε-cleavage of N-cadherin', 'display_name': 'Activity-dependent regulation of β-catenin via ε-cleavage of N-cadherin', 'publication_year': 2006, 'publication_date': '2006-07-01', 'ids': {'openalex': 'https://openalex.org/W1988597344', 'doi': 'https://doi.org/10.1016/j.bbrc.2006.04.157', 'mag': '1988597344', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16707106'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2006.04.157', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102112049', 'display_name': 'Kengo Uemura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kengo Uemura', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103512636', 'display_name': 'Takeshi Kihara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takeshi Kihara', 'raw_affiliation_strings': ['Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022475345', 'display_name': 'Akira Kuzuya', 'orcid': 'https://orcid.org/0009-0003-4925-9099'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akira Kuzuya', 'raw_affiliation_strings': ['Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068637876', 'display_name': 'Katsuya Okawa', 'orcid': 'https://orcid.org/0009-0007-2096-5124'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Katsuya Okawa', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086074293', 'display_name': 'Takaaki Nishimoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takaaki Nishimoto', 'raw_affiliation_strings': ['Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058080620', 'display_name': 'Haruhiko Bito', 'orcid': 'https://orcid.org/0000-0001-6315-9594'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Haruhiko Bito', 'raw_affiliation_strings': ['Department of Neurochemistry, The University of Tokyo, Graduate School of Medicine, Tokyo 113-8654, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurochemistry, The University of Tokyo, Graduate School of Medicine, Tokyo 113-8654, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068706107', 'display_name': 'Haruaki Ninomiya', 'orcid': 'https://orcid.org/0000-0001-5412-1180'}, 'institutions': [{'id': 'https://openalex.org/I4588055', 'display_name': 'Tottori University', 'ror': 'https://ror.org/024yc3q36', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4588055']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Haruaki Ninomiya', 'raw_affiliation_strings': ['Department of Neurobiology, Tottori University Faculty of Medicine, Yonago 683-8503, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurobiology, Tottori University Faculty of Medicine, Yonago 683-8503, Japan', 'institution_ids': ['https://openalex.org/I4588055']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044029573', 'display_name': 'Hachiro Sugimoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hachiro Sugimoto', 'raw_affiliation_strings': ['Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044809052', 'display_name': 'Ayae Kinoshita', 'orcid': 'https://orcid.org/0009-0000-9017-3754'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Ayae Kinoshita', 'raw_affiliation_strings': ['Department of Health Science, Faculty of Medicine, Kyoto University, Kyoto 606-8507, Japan', 'Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Health Science, Faculty of Medicine, Kyoto University, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}, {'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5088123955', 'display_name': 'Shun Shimohama', 'orcid': 'https://orcid.org/0000-0001-9264-8848'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shun Shimohama', 'raw_affiliation_strings': ['Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5044809052'], 'corresponding_institution_ids': ['https://openalex.org/I22299242'], 'apc_list': {'value': 2770, 'currency': 'USD', 'value_usd': 2770, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.256, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 40, 'citation_normalized_percentile': {'value': 0.844285, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '345', 'issue': '3', 'first_page': '951', 'last_page': '958'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt Signaling in Development and Disease', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt Signaling in Development and Disease', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Protein Arginine Methylation in Mammals', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12061', 'display_name': 'Molecular Mechanisms of Axon Guidance', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cell-signaling', 'display_name': 'Cell Signaling', 'score': 0.516403}], 'concepts': [{'id': 'https://openalex.org/C149402561', 'wikidata': 'https://www.wikidata.org/wiki/Q24776048', 'display_name': 'Cadherin', 'level': 3, 'score': 0.769256}, {'id': 'https://openalex.org/C30145163', 'wikidata': 'https://www.wikidata.org/wiki/Q384104', 'display_name': 'Catenin', 'level': 4, 'score': 0.73382795}, {'id': 'https://openalex.org/C1292079', 'wikidata': 'https://www.wikidata.org/wiki/Q3817769', 'display_name': 'Transactivation', 'level': 4, 'score': 0.63848644}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6246704}, {'id': 'https://openalex.org/C175344181', 'wikidata': 'https://www.wikidata.org/wiki/Q907198', 'display_name': 'Presenilin', 'level': 4, 'score': 0.5830807}, {'id': 'https://openalex.org/C112592302', 'wikidata': 'https://www.wikidata.org/wiki/Q1207387', 'display_name': 'Excitatory postsynaptic potential', 'level': 3, 'score': 0.5121639}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.5007093}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4642167}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.41987395}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.40681022}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.35298157}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.33443573}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.3103622}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.25866163}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.18995199}, {'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.15523976}, {'id': 'https://openalex.org/C502032728', 'wikidata': 'https://www.wikidata.org/wiki/Q11081', 'display_name': "Alzheimer's disease", 'level': 3, 'score': 0.14868039}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.120986015}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08378896}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.07305628}, {'id': 'https://openalex.org/C17077164', 'wikidata': 'https://www.wikidata.org/wiki/Q1185869', 'display_name': 'Inhibitory postsynaptic potential', 'level': 2, 'score': 0.06376544}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D021581', 'descriptor_name': 'Active Transport, Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053764', 'descriptor_name': 'Presenilin-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015533', 'descriptor_name': 'Transcriptional Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2006.04.157', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16707106', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W1534001036', 'https://openalex.org/W1554815317', 'https://openalex.org/W1655404681', 'https://openalex.org/W1660631781', 'https://openalex.org/W1879138788', 'https://openalex.org/W1912510903', 'https://openalex.org/W1971775650', 'https://openalex.org/W1987888225', 'https://openalex.org/W1989215255', 'https://openalex.org/W1990752558', 'https://openalex.org/W2004191360', 'https://openalex.org/W2010625082', 'https://openalex.org/W2010710842', 'https://openalex.org/W2014573698', 'https://openalex.org/W2014574033', 'https://openalex.org/W2015964634', 'https://openalex.org/W2019486380', 'https://openalex.org/W2047813645', 'https://openalex.org/W2056833504', 'https://openalex.org/W2057709960', 'https://openalex.org/W2059738400', 'https://openalex.org/W2066673889', 'https://openalex.org/W2071623902', 'https://openalex.org/W2076953949', 'https://openalex.org/W2078528430', 'https://openalex.org/W2082773762', 'https://openalex.org/W2091475538', 'https://openalex.org/W2092235352', 'https://openalex.org/W2111314225', 'https://openalex.org/W2127113850', 'https://openalex.org/W2138447190', 'https://openalex.org/W2148294117', 'https://openalex.org/W2167157682', 'https://openalex.org/W2168334242', 'https://openalex.org/W4247521408', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4250648966', 'https://openalex.org/W4240769625', 'https://openalex.org/W3144279060', 'https://openalex.org/W2142544866', 'https://openalex.org/W2116681496', 'https://openalex.org/W2096292628', 'https://openalex.org/W2089875622', 'https://openalex.org/W1986281697', 'https://openalex.org/W1587820133', 'https://openalex.org/W1513677097'], 'abstract_inverted_index': {'N-cadherin': [0, 24, 32, 97, 122], 'is': [1, 13, 33, 112], 'essential': [2, 113], 'for': [3, 114], 'excitatory': [4], 'synaptic': [5, 18, 115, 129], 'contact': [6, 78], 'in': [7, 37, 54, 75, 118], 'the': [8, 62, 106, 119, 128], 'hippocampus.': [9], 'Presenilin': [10], '1': [11], '(PS1)': [12], 'located': [14], 'at': [15], 'sites': [16], 'of': [17, 42, 52, 69, 86, 91, 96, 108, 121], 'contact,': [19], 'forming': [20], 'a': [21, 47, 66, 76], 'complex': [22], 'with': [23, 132], 'and': [25, 64, 71, 93, 99], 'β-catenin.': [26], 'Here,': [27], 'we': [28], 'report': [29], 'that': [30], 'human': [31], 'cleaved': [34], 'by': [35], 'PS1/γ-secretase': [36], 'response': [38], 'to': [39, 58, 61, 127], 'physiological': [40], 'concentration': [41], 'glutamate': [43], '(Glu)': [44], 'stimulation,': [45], 'yielding': [46], 'fragment': [48], 'Ncad/CTF2.': [49], 'The': [50], 'expression': [51], 'Ncad/CTF2': [53], 'neuronal': [55], 'cells': [56], 'led': [57], 'its': [59], 'translocation': [60], 'nucleus,': [63], 'caused': [65], 'prominent': [67], 'enhancement': [68], 'cytoplasmic': [70], 'nuclear': [72, 103], 'β-catenin': [73, 87, 102, 110], 'levels': [74], 'cell–cell': [77], 'dependent': [79], 'manner,': [80], 'via': [81], 'following': [82], 'mechanisms:': [83], '1,': [84], 'inhibition': [85, 95], 'phosphorylation;': [88], '2,': [89], 'transactivation': [90], 'β-catenin;': [92], '3,': [94], 'transcription,': [98], 'finally': [100], 'enhanced': [101], 'signaling.': [104], 'Since': [105], 'regulation': [107], 'cellular': [109], 'level': [111], 'function,': [116], 'disruption': [117], 'cleavage': [120], 'may': [123], 'be': [124], 'causally': [125], 'linked': [126], 'dysfunction': [130], 'associated': [131], "Alzheimer's": [133], 'disease': [134], '(AD).': [135]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1988597344', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-08-21T15:21:40.360219', 'created_date': '2016-06-24'}