Publication Information

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[106, 252, 319], 'genetic': [108, 146, 397, 1655], 'basis': [109, 147], 'these': [111, 404], 'different': [112, 358, 366, 370, 381, 389], 'kidney': [115, 149, 159, 169, 364, 384, 1428, 1464, 1487], 'cancer': [116, 150, 170, 340, 385, 405, 477, 1616], 'provide': [118, 130, 408, 422], 'better': [119], 'methods': [120], 'for': [121, 133, 197, 206, 248, 289, 425, 833, 890, 1791, 1841, 1880, 1967, 2005], 'early': [122], 'diagnosis': [123], 'disease': [126, 429, 659, 839, 893, 909, 929], 'as': [127, 129, 419, 421], 'well': [128, 420], 'foundation': [132, 424], 'development': [135, 427], 'molecular': [137, 401, 431, 596], 'therapeutic': [138, 432], 'approaches.': [139], 'Materials': [140], 'Methods:': [142], 'To': [143], 'identify': [144, 194], 'we': [151], 'studied': [152, 307], 'families': [153, 308, 1254], 'an': [155, 2201], 'inherited': [156, 198, 208, 237, 1763], 'predisposition': [157], 'cancer.': [160, 1562, 1637, 1772], 'Families': [161], 'in': [162, 321, 326, 478, 600, 632, 649, 656, 674, 710, 718, 734, 775, 799, 836, 873, 925, 948, 973, 1182, 1211, 1264, 1280, 1289, 1330, 1408, 1440, 1481, 1499, 1514, 1554, 1657, 1680, 1701, 1742, 1758, 1848, 1887, 2257], 'which': [163], '2': [164, 457, 1360], 'or': [165, 752], 'more': [166], 'individuals': [167], 'had': [168], 'underwent': [171], 'a': [172, 182, 229, 345, 355, 395, 714, 1110, 1116, 1136, 1183, 1186, 1203, 1311, 1424, 1457, 1482, 1555, 1609, 1658, 1888], 'comprehensive': [173], 'evaluation': [174, 1516], 'determine': [176], 'whether': [177], 'they': [178, 392], 'were': [179], 'affected': [180, 328], 'hereditary': [183, 240, 333, 737, 778, 876, 1256, 1537, 1702], 'form': [184, 209, 235, 263, 272], 'carcinoma.': [187, 202, 317, 337, 438, 499, 513, 530, 567, 634, 740, 950, 1241], 'linkage': [189], 'analysis': [190, 1653], 'was': [191, 220, 244, 251, 268, 285, 292], 'performed': [192], 'gene': [196, 205, 219, 223, 247, 288, 325, 647, 947, 972, 1022, 1107, 1484], 'forms': [199, 877, 1109], 'Results:': [203], 'cell': [212, 336, 476, 498, 511, 534, 653, 687, 739, 780, 977, 1240, 1347, 1406, 1615, 1636, 1662, 1676, 1771], 'carcinoma': [214, 276, 688, 1259, 1407], 'associated': [215, 279, 1459, 1612], 'von': [217, 626, 657, 682, 711, 837, 891, 907, 927, 968, 1086, 1104, 1163], 'Hippel-Lindau': [218, 591, 627, 658, 683, 712, 838, 892, 908, 928, 969, 1087, 1105, 1164], 'identified.': [221, 245, 305], 'This': [222], 'has': [224, 303], 'been': [225, 304], 'found': [226, 254], 'be': [228, 256, 343], 'tumor': [230, 910, 930, 970, 1052, 1073, 1088, 1518], 'suppressor': [231, 911, 931, 946, 971, 1053, 1074, 1089], 'gene.': [232, 629, 912, 932, 1054], 'A': [233, 260, 270, 1649, 2197, 2346, 2385], 'new': [234], 'carcinoma,': [239, 243], 'papillary': [241, 315, 1238, 1257, 1290, 1304, 1331, 1538, 1560, 1674, 1703, 1715, 1769], 'condition': [250, 291, 1611], 'proto-oncogene': [258, 1288, 1329], 'c-Met.': [259], 'previously': [261], 'unidentified': [262], 'familial': [265, 271, 1651], 'oncocytoma': [267, 278], 'found.': [269, 286], 'Birt': [281, 1454], 'Hogg': [282], 'Dubé': [283], 'syndrome': [284], 'localized': [293], 'on': [294, 1922, 2295], 'short': [296], 'arm': [297], 'chromosome': [299, 1468], '17': [300, 791], 'it': [302], 'cutaneous': [310, 1573, 1587, 1606], 'leiomyomas,': [311], 'uterine': [312, 1632, 1764], 'leiomyomas': [313, 1633], 'mutations': [320, 924, 961, 1263, 1279, 1309, 1325, 1757], 'fumarate': [323], 'hydratase': [324], 'patients': [327, 680, 735, 776, 874, 1500], 'disorder,': [331], 'namely': [332], 'leiomyoma': [334], 'Conclusions:': [338], 'used': [341], 'considered': [344], 'single': [346], 'disease.': [347], 'It': [348], 'is': [349, 1608], 'now': [350], 'known': [351], 'that': [352, 373], 'there': [353], 'number': [356], 'cancers': [361], 'histological': [367], 'patterns': [368], 'clinical': [371, 413, 593, 693, 1678], 'courses': [372, 414], 'appear': [374], 'respond': [376], 'differently': [377], 'therapy.': [379], 'These': [380], 'caused': [387], 'genes,': [390], 'ie': [391], 'each': [393], 'have': [394], 'distinct': [396, 1312], 'basis.': [398], 'Understanding': [399], 'pathways': [402], 'genes': [406], 'should': [407], 'insight': [409], 'into': [410], 'their': [411], 'varying': [412], 'responses': [416], 'treatment': [418], 'specific': [430, 1204], 'strategies.': [433], 'References': [434], '1': [435], ':': [436, 458, 471, 488, 508, 527, 545, 565, 589, 622, 641, 669, 703, 730, 749, 771, 792, 811, 828, 855, 869, 888, 903, 919, 940, 958, 986, 1004, 1020, 1037, 1065, 1082, 1102, 1134, 1150, 1174, 1200, 1236, 1250, 1275, 1300, 1323, 1340, 1371, 1388, 1403, 1421, 1437, 1453, 1479, 1511, 1533, 1550, 1571, 1584, 1595, 1604, 1628, 1648, 1672, 1691, 1713, 1732, 1755], 'Renal': [437, 528, 566, 755, 1438, 1819, 1842, 1890, 1932, 1969, 2007, 2111, 2120, 2194, 2206, 2293, 2325], 'In:': [439, 551, 568, 598, 1721], 'Metabolic': [441], '&': [442, 555, 2412], 'Molecular': [443, 546, 2143, 2302], 'Bases': [444], 'Inherited': [446, 1629, 2205], 'Disease.': [447], 'Edited': [448, 575, 610], '.': [450, 552, 577, 612, 1722], 'New': [451, 578], 'York:': [452, 579], 'McGraw-Hill2001:': [453], '907.': [454, 1686], 'Google': [455, 468, 485, 505, 524, 542, 562, 586, 619, 638, 666, 700, 727, 746, 768, 789, 808, 825, 852, 866, 885, 900, 916, 937, 955, 983, 1001, 1017, 1034, 1062, 1079, 1099, 1131, 1147, 1171, 1197, 1233, 1247, 1272, 1297, 1320, 1337, 1368, 1385, 1400, 1418, 1434, 1450, 1476, 1508, 1530, 1547, 1568, 1581, 1592, 1601, 1625, 1645, 1669, 1688, 1710, 1729, 1752, 1777], 'Scholar': [456, 469, 486, 506, 525, 543, 563, 587, 620, 639, 667, 701, 728, 747, 769, 790, 809, 826, 853, 867, 886, 901, 917, 938, 956, 984, 1002, 1018, 1035, 1063, 1080, 1100, 1132, 1148, 1172, 1198, 1234, 1248, 1273, 1298, 1321, 1338, 1369, 1386, 1401, 1419, 1435, 1451, 1477, 1509, 1531, 1548, 1569, 1582, 1593, 1602, 1626, 1646, 1670, 1689, 1711, 1730, 1753, 1778], 'statistics,': [460], '1999.': [461], 'CA': [462], 'J': [464, 500, 537, 662, 695, 723, 741, 784, 804, 848, 862, 880, 1012, 1029, 1193, 1229, 1242, 1316, 1363, 1380, 1412, 1445, 1471, 1525, 1541, 1563, 1575, 1621, 1665, 1683, 2186, 2320], 'Clin1999;': [465], '49:': [466], '8.': [467], '3': [470], 'Rising': [472], 'incidence': [473], 'United': [480], 'States.': [481], 'JAMA1999;': [482], '281:': [483], '1628.': [484], '4': [487, 1974, 2397], 'Prognostic': [489], 'significance': [490], '1997': [493], 'TNM': [494], 'classification': [495], 'Urol1999;': [501, 863], '162:': [502], '1277.': [503], 'Link,': [504, 699, 745, 788, 884, 1246, 1384, 1529, 1687], '5': [507, 1378], 'Human': [509, 573], 'Virchows': [514], 'Arch': [515, 1396, 1430], 'B': [516, 1093, 2028], 'Cell': [517, 1167, 1820, 1843, 1970, 2195, 2326], 'Pathol': [518], 'Incl': [519], 'Mol': [520], 'Pathol1985;': [521], '48:': [522], '207.': [523], '6': [526], 'medullary': [529], 'seventh': [532], 'sickle': [533], 'nephropathy.': [535], 'Am': [536, 661, 722, 1011, 1315, 1413, 1444, 1470, 1576, 1620], 'Surg': [538, 1446], 'Pathol1995;': [539], '19:': [540], '1.': [541, 561], '7': [544], 'biology': [547], 'genitourinary': [549], 'cancers.': [550, 1540], 'Philadelphia:': [553, 613], 'Lippincott-Williams': [554], 'Wilkins2001:': [556], '1343.': [557], 'chapt.': [558, 584, 1727], '34,': [559], 'sect.': [560, 582], '8': [564], 'Cancer.': [574], 'McGraw-Hill2002:': [580], '449.': [581], 'III,': [583], '27.': [585], '9': [588], 'Von': [590], 'disease:': [592, 692, 713], 'review': [594], 'genetics.': [597], 'Problems': [599], 'Urologic': [601, 1781], 'Surgery:': [602], 'Benign': [603], 'Malignant': [605], 'Tumors': [606, 1886, 2294], 'Kidney.': [609], 'J.': [614], 'B.': [615], 'Lippincott': [616], 'Co.1990:': [617], '312.': [618], '10': [621, 1681], 'Identification': [623, 904], '(VHL)': [628], 'Its': [630], 'role': [631], 'JAMA1995;': [635], '273:': [636], '564.': [637], '11': [640], 'Allelic': [642], 'deletions': [643], 'VHL': [646, 944, 1021, 1051, 1072], 'detected': [648], 'multiple': [650, 841, 1390, 1558, 1586], 'microscopic': [651, 672], 'lesions': [655, 673, 709], 'patients.': [660, 720], 'Pathol1996;': [663], '149:': [664], '2089.': [665], '12': [668], 'Prevalence': [670], 'grossly': [675], 'normal': [676], 'parenchyma': [678], 'from': [679], 'disease,': [684], 'sporadic': [685, 1303], 'no': [690], 'implications.': [694], 'Urol1995;': [696, 742, 805, 1684], '154:': [697], '2010.': [698], '13': [702], 'natural': [705], 'history': [706], 'serial': [715], 'CT': [716, 759], 'study': [717, 991, 1376], '28': [719, 1003], 'AJR': [721], 'Roentgenol1992;': [724], '159:': [725, 1623], '1229.': [726], '14': [729], 'Parenchymal': [731, 772, 1551], 'sparing': [732, 773, 801, 1552], 'surgery': [733, 774, 1553], '153:': [743, 1685], '913.': [744], '15': [748], 'Small': [750], '(<': [751], '=': [753], '3-cm)': [754], 'masses:': [756], 'detection': [757, 921], 'versus': [760], 'US': [761], 'pathologic': [763], 'correlation.': [764], 'Radiology1996;': [765], '198:': [766], '785.': [767], '16': [770], 'carcinoma:': [781, 1677, 1717], '10-year': [782], 'experience.': [783], 'Urol2001;': [785, 1564], '165:': [786, 1565], '777.': [787], 'Evaluation': [793], 'color': [795], 'Doppler': [796], 'intraoperative': [797], 'ultrasound': [798, 1513], 'parenchymal': [800], 'surgery.': [803], '152:': [806], '1984.': [807], '18': [810], 'Surgical': [812], 'management': [813], 'pheochromocytoma': [815], 'use': [818], 'metyrosine.': [820], 'Ann': [821], 'Surg1990;': [822], '212:': [823], '621.': [824], '19': [827], 'Plasma': [829], 'normetanephrine': [830], 'metanephrine': [832], 'detecting': [834], 'pheochromocytomas': [835], 'endocrine': [842], 'neoplasia': [843], 'type': [844], '2.': [845, 1728], 'N': [846, 1191, 1227, 2370], 'Engl': [847, 1192, 1228], 'Med1999;': [849], '340:': [850], '1872.': [851], '20': [854, 1885], 'Pheochromocytoma:': [856], 'evaluation,': [857], 'diagnosis,': [858], 'treatment.': [860], 'World': [861], '17:': [864], '35.': [865], '21': [868], 'Laparoscopic': [870], 'partial': [871], 'adrenalectomy': [872], 'pheochromocytoma.': [879, 1010], 'Urol2000;': [881], '164:': [882], '14.': [883], '22': [887], 'Screening': [889], 'DNA-polymorphism': [895], 'analysis.': [896], 'JAMA1992;': [897], '267:': [898], '1226.': [899], '23': [902], 'Science1993;': [913], '260:': [914], '1317.': [915], '24': [918], 'Improved': [920], 'germline': [923], 'Hum': [933, 1013, 1472], 'Mut1998;': [934], '12:': [935], '417.': [936], '25': [939], 'Mutations': [941, 1480, 2254], 'tumour': [945], 'Nat': [951, 1166, 1293, 1706, 1773], 'Genet1994;': [952], '7:': [953], '85.': [954], '26': [957], 'Frequent': [959], 'somatic': [960, 1278], 'loss': [963], 'heterozygosity': [965], 'primary': [974], 'human': [975, 1114], 'carcinomas.': [978, 1027, 1292, 1333, 1663, 1705], 'Res1994;': [980], '54:': [981], '2852.': [982], '27': [985], 'Mutation': [987, 1005, 1921], 'cancer:': [989, 1007], 'statistical': [990], 'retinoblastoma.': [993], 'Proc': [994, 1055, 1124, 1140, 1638], 'Natl': [995, 1056, 1125, 1141, 1639], 'Acad': [996, 1057, 1126, 1142, 1414, 1577, 1640], 'Sci': [997, 1030, 1058, 1127, 1143, 1641], 'USA1971;': [998], '68:': [999], '820.': [1000], 'neuroblastoma': [1008], 'Genet1972;': [1014], '24:': [1015], '514.': [1016], '29': [1019], 'mutation': [1023], 'clear-cell': [1025], 'Am1995;': [1031], '1:': [1032], '180.': [1033], '30': [1036], 'Post-transcriptional': [1038], 'regulation': [1039], 'vascular': [1041], 'endothelial': [1042], 'growth': [1043, 1345], 'factor': [1044, 1154], 'mRNA': [1045], 'product': [1048, 1108], 'USA1996;': [1059], '93:': [1060], '10589.': [1061], '31': [1064], 'Inhibition': [1066], 'transcription': [1068], 'elongation': [1069], 'protein.': [1075, 1165], 'Science1995;': [1076, 1096], '269:': [1077, 1097], '1402.': [1078], '32': [1081], 'Binding': [1083], 'protein': [1090], 'Elongin': [1092], 'C.': [1095], '1444.': [1098], '33': [1101], 'tumor-suppressor': [1106], 'stable': [1111], 'complex': [1112], 'CUL-2,': [1115], 'member': [1117], 'Cdc53': [1120], 'family': [1121], 'proteins.': [1123], 'USA1997;': [1128], '94:': [1129], '2156.': [1130], '34': [1133], 'VHL:': [1135], 'very': [1137], 'hip': [1138], 'ligase.': [1139], 'USA1999;': [1144], '96:': [1145], '12230.': [1146], '35': [1149], 'Ubiquitination': [1151], 'hypoxia-inducible': [1153], 'requires': [1155], 'direct': [1156], 'binding': [1157], 'beta-domain': [1160], 'Biol2000;': [1168], '2:': [1169, 1506], '423.': [1170], '36': [1173], 'Effect': [1175], 'tyrosine': [1178, 1209, 1282], 'kinase': [1179, 1210, 1283], 'inhibitor': [1180, 1205], 'STI571': [1181], 'patient': [1184, 1556], 'metastatic': [1187], 'gastrointestinal': [1188], 'stromal': [1189], 'tumor.': [1190], 'Med2001;': [1194, 1230], '344:': [1195, 1231], '1052.': [1196], '37': [1199], 'Activity': [1201], 'BCR-ABL': [1208], 'blast': [1213], 'crisis': [1214], 'chronic': [1216], 'myeloid': [1217], 'leukemia': [1218, 1222], 'acute': [1220], 'lymphoblastic': [1221], 'Philadelphia': [1225], 'chromosome.': [1226], '1038.': [1232], '38': [1235], 'Hereditary': [1237, 1301, 1389, 1673, 1714, 2191], 'Urol1994;': [1243], '151:': [1244], '561.': [1245], '39': [1249], 'Two': [1251, 1849], 'North': [1252], 'American': [1253, 1801, 2416], 'identical': [1261], 'novel': [1262, 1425, 1483], 'MET': [1266, 1287, 1328, 1699], 'proto-oncogene.': [1267], 'Res1998;': [1269], '58:': [1270, 1599], '1719.': [1271], '40': [1274], 'Germline': [1276, 1756, 1919], 'domain': [1284, 1361], 'Genet1997;': [1294], '16:': [1295], '68.': [1296], '41': [1299], 'carcinomas': [1306], 'c-met': [1308], 'share': [1310], 'morphological': [1313], 'phenotype.': [1314], 'Pathol1999;': [1317], '155:': [1318], '517.': [1319], '42': [1322], 'Novel': [1324], 'Oncogene1999;': [1334], '18:': [1335], '2343.': [1336], '43': [1339], 'Potent': [1341], 'blockade': [1342], 'hepatocyte': [1344], 'factor-stimulated': [1346], 'motility,': [1348], 'matrix': [1349], 'invasion': [1350], 'branching': [1352], 'morphogenesis': [1353], 'antagonists': [1355], 'Grb2': [1357], 'Src': [1358], 'homology': [1359], 'interactions.': [1362], 'Biol': [1364], 'Chem2001;': [1365], '276:': [1366], '14308.': [1367], '44': [1370], 'Familial': [1372, 1572, 1585, 1596, 1605, 2110], 'oncocytoma:': [1374], 'clinicopathologic': [1375], 'families.': [1379, 1682], 'Urol1998;': [1381], '160:': [1382], '335.': [1383], '45': [1387], 'fibrofolliculomas': [1391], 'trichodiscomas': [1393], 'acrochordons.': [1395], 'Dermatol1977;': [1397], '113:': [1398], '1674.': [1399], '46': [1402], 'Bilateral': [1404, 1931], 'Birt-Hogg-Dube': [1410, 1422, 1442, 1502, 1744], 'syndrome.': [1411, 1443, 1503, 1745], 'Dermatol1993;': [1415], '29:': [1416], '1055.': [1417], '47': [1420], 'syndrome:': [1423], 'marker': [1426], 'neoplasia.': [1429], 'Dermatol1999;': [1431], '135:': [1432], '1195.': [1433], '48': [1436], 'Pathol2002;': [1447], '26:': [1448], '1542.': [1449], '49': [1452], 'Hogg-Dube': [1455], 'syndrome,': [1456], 'genodermatosis': [1458], 'spontaneous': [1461, 1740], 'pneumothorax': [1462, 1741], 'neoplasia,': [1465], 'maps': [1466], '17p11.2.': [1469], 'Genet2001;': [1473], '69:': [1474], '876.': [1475], '50': [1478], 'lead': [1485], 'tumors,': [1488], 'lung': [1489], 'wall': [1490], 'defects,': [1491], 'benign': [1493], 'hair': [1497], 'follicle': [1498], 'Cell2002;': [1505], '157.': [1507], '51': [1510], 'Intraoperative': [1512], 'involvement': [1519], 'inferior': [1522], 'vena': [1523], 'cava.': [1524], 'Urol1993;': [1526], '150:': [1527], '13.': [1528], '52': [1532], 'Imaging': [1534], 'features': [1535], 'Comput': [1542], 'Assist': [1543], 'Tomogr1997;': [1544], '21:': [1545], '737.': [1546], '53': [1549], 'bilateral': [1559], '1623.': [1566], 'Abstract,': [1567], '54': [1570], 'leiomyomatosis.': [1574], 'Dermatol1981;': [1578], '4:': [1579], '430.': [1580], '55': [1583], 'leiomyomas.': [1588], 'Dermatology1995;': [1589], '191:': [1590], '295.': [1591], '56': [1594], 'leiomyomata.': [1597], 'Cutis1996;': [1598], 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