Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1988427471', 'doi': 'https://doi.org/10.1016/j.ejphar.2010.08.030', 'title': 'Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice', 'display_name': 'Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice', 'publication_year': 2010, 'publication_date': '2010-09-04', 'ids': {'openalex': 'https://openalex.org/W1988427471', 'doi': 'https://doi.org/10.1016/j.ejphar.2010.08.030', 'mag': '1988427471', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20826146'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.ejphar.2010.08.030', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S187816532', 'display_name': 'European Journal of Pharmacology', 'issn_l': '0014-2999', 'issn': ['0014-2999', '1879-0712'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'http://psasir.upm.edu.my/id/eprint/13161/1/Antinociceptive%20activity%20of%20a%20synthetic%20chalcone.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5065819966', 'display_name': 'Azam Shah Mohamad', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'A.S. Mohamad', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069680707', 'display_name': 'Mohamad Nadeem Akhtar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'M.N. Akhtar', 'raw_affiliation_strings': ['Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103718961', 'display_name': 'Z.A. Zakaria', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'Z.A. Zakaria', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082255391', 'display_name': 'Enoch Kumar Perimal', 'orcid': 'https://orcid.org/0000-0003-2666-7340'}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'E.K. Perimal', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016151143', 'display_name': 'Syamimi Khalid', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'S. Khalid', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042460691', 'display_name': 'P.A. Mohd', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'P.A. Mohd', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002541610', 'display_name': 'Mohamed Hanief Khalid', 'orcid': 'https://orcid.org/0000-0002-6363-8939'}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'M.H. Khalid', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029782119', 'display_name': 'Daud Ahmad Israf', 'orcid': 'https://orcid.org/0000-0003-2936-6156'}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'D.A. Israf', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}, {'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064318074', 'display_name': 'Nordin H. Lajis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': False, 'raw_author_name': 'N.H. Lajis', 'raw_affiliation_strings': ['Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013617875', 'display_name': 'Mohd Roslan Sulaiman', 'orcid': 'https://orcid.org/0000-0002-4580-1296'}, 'institutions': [{'id': 'https://openalex.org/I130343225', 'display_name': 'Universiti Putra Malaysia', 'ror': 'https://ror.org/02e91jd64', 'country_code': 'MY', 'type': 'education', 'lineage': ['https://openalex.org/I130343225']}], 'countries': ['MY'], 'is_corresponding': True, 'raw_author_name': 'M.R. Sulaiman', 'raw_affiliation_strings': ['Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Natural Products, Institute of Biosciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}, {'raw_affiliation_string': 'Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia', 'institution_ids': ['https://openalex.org/I130343225']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5013617875'], 'corresponding_institution_ids': ['https://openalex.org/I130343225'], 'apc_list': {'value': 2790, 'currency': 'USD', 'value_usd': 2790, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.988, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 56, 'citation_normalized_percentile': {'value': 0.999845, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '647', 'issue': '1-3', 'first_page': '103', 'last_page': '109'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Licorice Roots', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Licorice Roots', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10196', 'display_name': 'Mechanisms and Management of Neuropathic Pain', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13792', 'display_name': 'Therapeutic Properties of Morinda citrifolia', 'score': 0.9927, 'subfield': {'id': 'https://openalex.org/subfields/2707', 'display_name': 'Complementary and alternative medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chalcone', 'display_name': 'Chalcone', 'score': 0.77429605}, {'id': 'https://openalex.org/keywords/nociception', 'display_name': 'Nociception', 'score': 0.511612}], 'concepts': [{'id': 'https://openalex.org/C15490471', 'wikidata': 'https://www.wikidata.org/wiki/Q2734305', 'display_name': 'Nociception', 'level': 3, 'score': 0.92276484}, {'id': 'https://openalex.org/C2780764945', 'wikidata': 'https://www.wikidata.org/wiki/Q899416', 'display_name': 'Chalcone', 'level': 2, 'score': 0.77429605}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4774152}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3834519}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.23662597}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.20387033}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.14722964}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.10428494}], 'mesh': [{'descriptor_ui': 'D047188', 'descriptor_name': 'Chalcones', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D005419', 'descriptor_name': 'Flavonoids', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000700', 'descriptor_name': 'Analgesics', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000700', 'descriptor_name': 'Analgesics', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000700', 'descriptor_name': 'Analgesics', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000700', 'descriptor_name': 'Analgesics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D047188', 'descriptor_name': 'Chalcones', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D047188', 'descriptor_name': 'Chalcones', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D047188', 'descriptor_name': 'Chalcones', 'qualifier_ui': 'Q000138', 'qualifier_name': 'chemical synthesis', 'is_major_topic': False}, {'descriptor_ui': 'D047188', 'descriptor_name': 'Chalcones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005419', 'descriptor_name': 'Flavonoids', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D005419', 'descriptor_name': 'Flavonoids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005419', 'descriptor_name': 'Flavonoids', 'qualifier_ui': 'Q000138', 'qualifier_name': 'chemical synthesis', 'is_major_topic': False}, {'descriptor_ui': 'D005419', 'descriptor_name': 'Flavonoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018698', 'descriptor_name': 'Glutamic Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018698', 'descriptor_name': 'Glutamic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008813', 'descriptor_name': 'Mice, Inbred ICR', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008956', 'descriptor_name': 'Models, Chemical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009043', 'descriptor_name': 'Motor Activity', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009043', 'descriptor_name': 'Motor Activity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010147', 'descriptor_name': 'Pain Measurement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010936', 'descriptor_name': 'Plant Extracts', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010936', 'descriptor_name': 'Plant Extracts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011930', 'descriptor_name': 'Reaction Time', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011930', 'descriptor_name': 'Reaction Time', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011957', 'descriptor_name': 'Receptors, Opioid', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011957', 'descriptor_name': 'Receptors, Opioid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.ejphar.2010.08.030', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S187816532', 'display_name': 'European Journal of Pharmacology', 'issn_l': '0014-2999', 'issn': ['0014-2999', '1879-0712'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://psasir.upm.edu.my/id/eprint/13161/1/Antinociceptive%20activity%20of%20a%20synthetic%20chalcone.pdf', 'pdf_url': 'http://psasir.upm.edu.my/id/eprint/13161/1/Antinociceptive%20activity%20of%20a%20synthetic%20chalcone.pdf', 'source': {'id': 'https://openalex.org/S4377196260', 'display_name': 'Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I130343225', 'host_organization_name': 'Universiti Putra Malaysia', 'host_organization_lineage': ['https://openalex.org/I130343225'], 'host_organization_lineage_names': ['Universiti Putra Malaysia'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20826146', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'http://psasir.upm.edu.my/id/eprint/13161/1/Antinociceptive%20activity%20of%20a%20synthetic%20chalcone.pdf', 'pdf_url': 'http://psasir.upm.edu.my/id/eprint/13161/1/Antinociceptive%20activity%20of%20a%20synthetic%20chalcone.pdf', 'source': {'id': 'https://openalex.org/S4377196260', 'display_name': 'Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I130343225', 'host_organization_name': 'Universiti Putra Malaysia', 'host_organization_lineage': ['https://openalex.org/I130343225'], 'host_organization_lineage_names': ['Universiti Putra Malaysia'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.53, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1883044208', 'https://openalex.org/W1968211538', 'https://openalex.org/W1971136775', 'https://openalex.org/W1987215319', 'https://openalex.org/W1994154408', 'https://openalex.org/W2005314332', 'https://openalex.org/W2005993314', 'https://openalex.org/W2009345240', 'https://openalex.org/W2011668678', 'https://openalex.org/W2015039992', 'https://openalex.org/W2020613944', 'https://openalex.org/W2037182281', 'https://openalex.org/W2039246411', 'https://openalex.org/W2042464457', 'https://openalex.org/W2042690759', 'https://openalex.org/W2049354917', 'https://openalex.org/W2052695476', 'https://openalex.org/W2056653713', 'https://openalex.org/W2064175661', 'https://openalex.org/W2066807788', 'https://openalex.org/W2073541816', 'https://openalex.org/W2074430538', 'https://openalex.org/W2079771237', 'https://openalex.org/W2085026402', 'https://openalex.org/W2088573471', 'https://openalex.org/W2123843261', 'https://openalex.org/W2125913406', 'https://openalex.org/W2129304351'], 'related_works': ['https://openalex.org/W657579294', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W1986764834', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'The': [0, 179], 'present': [1, 180], 'study': [2], 'examined': [3], 'the': [4, 51, 59, 70, 83, 87, 94, 105, 125, 133, 151, 155, 158, 164], 'potential': [5], 'antinociceptive': [6, 139], 'activity': [7], 'of': [8, 64, 86, 97, 104, 112, 154, 173, 195], 'flavokawin': [9, 27, 98], 'B': [10, 28, 99], "(6'-hydroxy-2',4'-dimethoxychalcone),": [11], 'a': [12, 121], 'synthetic': [13], 'chalcone': [14], 'using': [15], 'chemical-': [16], 'and': [17, 33, 41, 47, 114, 137, 163, 192, 203], 'thermal-induced': [18], 'nociception': [19], 'models': [20, 194], 'in': [21, 50, 82, 124, 132, 157, 197], 'mice.': [22], 'It': [23, 73], 'was': [24, 74, 141, 168], 'demonstrated': [25, 76], 'that': [26, 77, 183, 199], '(FKB;': [29], '0.3,': [30], '1,': [31], '3': [32], '10': [34], 'mg/kg)': [35], 'administered': [36], 'via': [37], 'both': [38, 190, 201], 'oral': [39], '(p.o.)': [40], 'intraperitoneal': [42], '(i.p.)': [43], 'routes': [44], 'produced': [45, 79, 185], 'significant': [46, 80, 102, 122], 'dose-dependent': [48], 'inhibition': [49, 81, 103], 'abdominal': [52], 'constrictions': [53], 'induced': [54, 108, 120], 'by': [55, 109, 171], 'acetic': [56], 'acid,': [57], 'with': [58], 'i.p.': [60], 'route': [61], 'producing': [62], 'antinociception': [63, 152, 187], 'approximately': [65], '7-fold': [66], 'more': [67], 'potent': [68], 'than': [69], 'p.o.': [71], 'route.': [72], 'also': [75, 119], 'FKB': [78, 156, 184], 'two': [84], 'phases': [85], 'formalin-induced': [88, 159], 'paw': [89, 160], 'licking': [90, 161], 'test.': [91], 'In': [92], 'addition,': [93], 'same': [95], 'treatment': [96], '(FKB)': [100], 'exhibited': [101, 200], 'neurogenic': [106], 'nociceptive': [107], 'intraplantar': [110], 'injections': [111], 'glutamate': [113], 'capsaicin.': [115], 'Likewise,': [116], 'this': [117], 'compound': [118], 'increase': [123], 'response': [126], 'latency': [127], 'period': [128], 'to': [129, 144], 'thermal': [130, 193], 'stimuli': [131], 'hot': [134, 165], 'plate': [135, 166], 'test': [136, 162, 167], 'its': [138], 'effect': [140, 153, 188], 'not': [142, 169], 'related': [143], 'muscle': [145], 'relaxant': [146], 'or': [147], 'sedative': [148], 'action.': [149], 'Moreover,': [150], 'affected': [170], 'pretreatment': [172], 'non-selective': [174], 'opioid': [175], 'receptor': [176], 'antagonist,': [177], 'naloxone.': [178], 'results': [181], 'indicate': [182], 'pronounced': [186], 'against': [189], 'chemical': [191], 'pain': [196], 'mice': [198], 'peripheral': [202], 'central': [204], 'analgesic': [205], 'activity.': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1988427471', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-17T15:04:56.407148', 'created_date': '2016-06-24'}