Publication Information

{'id': 'https://openalex.org/W1988363942', 'doi': 'https://doi.org/10.1093/intimm/5.11.1451', 'title': 'Co-stimulation via CD28 induces activation of a refractory subset of MRL-<i>Ipr/Ipr</i> T lymphocytes', 'display_name': 'Co-stimulation via CD28 induces activation of a refractory subset of MRL-<i>Ipr/Ipr</i> T lymphocytes', 'publication_year': 1993, 'publication_date': '1993-01-01', 'ids': {'openalex': 'https://openalex.org/W1988363942', 'doi': 'https://doi.org/10.1093/intimm/5.11.1451', 'mag': '1988363942', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7903158'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/intimm/5.11.1451', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S5544371', 'display_name': 'International Immunology', 'issn_l': '0953-8178', 'issn': ['0953-8178', '1460-2377'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087229069', 'display_name': 'James L. Clements', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James L. Clements', 'raw_affiliation_strings': ['Rheumatology and Clinical Immunology Unit, University of Vermont College of Medicine, Burlington 05405.'], 'affiliations': [{'raw_affiliation_string': 'Rheumatology and Clinical Immunology Unit, University of Vermont College of Medicine, Burlington 05405.', 'institution_ids': ['https://openalex.org/I111236770']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088505571', 'display_name': 'Genine Winslow', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Genine Winslow', 'raw_affiliation_strings': ['University of California at Berkeley'], 'affiliations': [{'raw_affiliation_string': 'University of California at Berkeley', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046281869', 'display_name': 'Christopher J. Donahue', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christopher Donahue', 'raw_affiliation_strings': ['UNIVERSITY OF VERMONT.'], 'affiliations': [{'raw_affiliation_string': 'UNIVERSITY OF VERMONT.', 'institution_ids': ['https://openalex.org/I111236770']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113493688', 'display_name': 'Sheldon M. Cooper', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sheldon M. Cooper', 'raw_affiliation_strings': ['UNIVERSITY OF VERMONT.'], 'affiliations': [{'raw_affiliation_string': 'UNIVERSITY OF VERMONT.', 'institution_ids': ['https://openalex.org/I111236770']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047117233', 'display_name': 'James P. Allison', 'orcid': 'https://orcid.org/0000-0001-8980-5697'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'James P. Allison', 'raw_affiliation_strings': ['Immunology'], 'affiliations': [{'raw_affiliation_string': 'Immunology', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058916400', 'display_name': 'Ralph C. Budd', 'orcid': 'https://orcid.org/0000-0001-8524-8758'}, 'institutions': [{'id': 'https://openalex.org/I111236770', 'display_name': 'University of Vermont', 'ror': 'https://ror.org/0155zta11', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111236770']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ralph C. Budd', 'raw_affiliation_strings': ['UNIVERSITY OF VERMONT.'], 'affiliations': [{'raw_affiliation_string': 'UNIVERSITY OF VERMONT.', 'institution_ids': ['https://openalex.org/I111236770']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3328, 'currency': 'USD', 'value_usd': 3328, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.547, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 13, 'citation_normalized_percentile': {'value': 0.520839, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '5', 'issue': '11', 'first_page': '1451', 'last_page': '1460'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9924, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9892, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ionomycin', 'display_name': 'Ionomycin', 'score': 0.61268675}], 'concepts': [{'id': 'https://openalex.org/C148125776', 'wikidata': 'https://www.wikidata.org/wiki/Q1622348', 'display_name': 'CD28', 'level': 4, 'score': 0.78097373}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.62931}, {'id': 'https://openalex.org/C2776989580', 'wikidata': 'https://www.wikidata.org/wiki/Q421320', 'display_name': 'Ionomycin', 'level': 3, 'score': 0.61268675}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.60439825}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.49380192}, {'id': 'https://openalex.org/C19317047', 'wikidata': 'https://www.wikidata.org/wiki/Q412037', 'display_name': 'T-cell receptor', 'level': 4, 'score': 0.48427933}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4728834}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.45630828}, {'id': 'https://openalex.org/C129374314', 'wikidata': 'https://www.wikidata.org/wiki/Q909381', 'display_name': 'Interleukin 21', 'level': 4, 'score': 0.43344533}, {'id': 'https://openalex.org/C114684123', 'wikidata': 'https://www.wikidata.org/wiki/Q419458', 'display_name': 'CD3', 'level': 4, 'score': 0.43096992}, {'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.42554834}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37489754}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3499392}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.34418336}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.22495604}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.22028938}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.18040684}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.11378357}], 'mesh': [{'descriptor_ui': 'D018106', 'descriptor_name': 'CD28 Antigens', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000945', 'descriptor_name': 'Antigens, Differentiation, T-Lymphocyte', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000945', 'descriptor_name': 'Antigens, Differentiation, T-Lymphocyte', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018801', 'descriptor_name': 'CD2 Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018106', 'descriptor_name': 'CD28 Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017635', 'descriptor_name': 'Clonal Anergy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007376', 'descriptor_name': 'Interleukin-2', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007376', 'descriptor_name': 'Interleukin-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015759', 'descriptor_name': 'Ionomycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015759', 'descriptor_name': 'Ionomycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008815', 'descriptor_name': 'Mice, Inbred Strains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016693', 'descriptor_name': 'Receptors, Antigen, T-Cell, alpha-beta', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D016693', 'descriptor_name': 'Receptors, Antigen, T-Cell, alpha-beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011971', 'descriptor_name': 'Receptors, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011971', 'descriptor_name': 'Receptors, Immunologic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013755', 'descriptor_name': 'Tetradecanoylphorbol Acetate', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013755', 'descriptor_name': 'Tetradecanoylphorbol Acetate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/intimm/5.11.1451', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S5544371', 'display_name': 'International Immunology', 'issn_l': '0953-8178', 'issn': ['0953-8178', '1460-2377'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7903158', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4294193037', 'https://openalex.org/W3004207027', 'https://openalex.org/W2969531067', 'https://openalex.org/W2398881750', 'https://openalex.org/W2389794721', 'https://openalex.org/W2015090226', 'https://openalex.org/W2009016562', 'https://openalex.org/W1970741281', 'https://openalex.org/W1599894629', 'https://openalex.org/W1518741832'], 'abstract_inverted_index': {'Peripheral': [0], 'lymphoid': [1], 'tissues': [2], 'of': [3, 10, 26, 31, 59, 66, 86, 109, 114, 129, 172, 182, 188, 195, 201, 242, 273, 285, 296, 315, 321], 'lpr': [4, 67, 102, 130, 218, 244, 251, 286, 329], 'mice': [5], 'contain': [6], 'a': [7, 116, 179, 230, 234, 240, 294, 303], 'large': [8], 'proportion': [9], 'TCR': [11, 206], 'alpha': [12, 207], 'beta/CD3+CD4-CD8-': [13], 'T': [14, 32, 54, 69, 76, 104, 132, 147, 174, 219, 245, 253, 288, 331, 335], 'cells': [15, 33, 55, 70, 105, 122, 133, 148, 196, 254, 289, 332], 'that': [16, 282, 299, 307], 'lack': [17, 295], 'surface': [18], 'CD2': [19, 183], 'and': [20, 163, 176, 211, 306, 333], 'express': [21, 106], 'the': [22, 49, 84, 95, 142, 169, 186, 189, 193, 199, 202, 228, 243, 271, 283, 313, 319, 326], 'B': [23], 'cell': [24, 166, 316], 'isoform': [25], 'CD45,': [27], 'B220.': [28], 'This': [29], 'subset': [30, 171], 'does': [34, 139, 290], 'not': [35, 140, 291, 302], 'proliferate': [36, 257], 'or': [37, 45, 87, 268, 276], 'produce': [38], 'IL-2': [39, 224, 275], 'in': [40, 83, 123, 134, 145, 157, 168, 178, 227, 258, 270, 318], 'response': [41, 135], 'to': [42, 120, 136, 214], 'mitogenic': [43], 'signals': [44], 'TCR-CD3': [46], 'ligation.': [47], 'At': [48], 'same': [50], 'time,': [51], 'these': [52, 64, 121, 250], 'abnormal': [53], 'display': [56], 'several': [57], 'characteristics': [58], 'an': [60, 259], 'activated': [61], 'phenotype.': [62], 'Collectively,': [63], 'properties': [65], 'CD4-CD8-': [68, 103, 131, 173, 217, 252, 287, 330], 'have': [71], 'functional': [72], 'parallels': [73, 327], 'with': [74, 125, 154, 159, 264], 'anergic': [75, 334], 'cells.': [77, 101, 220, 246, 336], 'A': [78], 'critical': [79], 'co-stimulatory': [80], 'molecule': [81], 'implicated': [82], 'prevention': [85], 'recovery': [88], 'from': [89, 293], 'anergy': [90], 'is': [91, 112, 225, 237, 301], 'CD28,': [92], 'which': [93, 111], 'binds': [94], 'ligand': [96], 'BB1/B7': [97], 'on': [98], 'certain': [99], 'accessory': [100], 'normal': [107, 146], 'levels': [108, 143, 184], 'CD28': [110, 137, 297], 'capable': [113], 'transducing': [115], 'strong': [117, 231], 'proliferative': [118], 'signal': [119], 'co-stimulation': [124, 138], 'mitogens.': [126], 'However,': [127, 192], 'proliferation': [128], 'reach': [141], 'observed': [144, 238], 'stimulated': [149, 263], 'under': [150], 'similar': [151, 213], 'conditions.': [152], 'Stimulation': [153], 'anti-CD28': [155, 277], 'mAb': [156, 267], 'conjunction': [158], 'phorbol': [160], 'myristate': [161], 'acetate': [162], 'ionomycin': [164], 'promotes': [165], 'cycling': [167, 317], 'CD2-': [170], 'cells,': [175], 'results': [177], 'slight': [180], 'induction': [181, 314], 'during': [185], 'course': [187], 'culture': [190, 203], 'period.': [191], 'majority': [194, 241], 'obtained': [197], 'at': [198], 'end': [200], 'period': [204], 'remain': [205], 'beta+': [208], 'CD4-CD8-,': [209], 'CD2low/-': [210], 'B220high,': [212], 'freshly': [215], 'isolated': [216], 'In': [221], 'contrast,': [222], 'if': [223], 'included': [226], 'cultures,': [229], 'shift': [232], 'toward': [233], 'CD2+': [235], 'phenotype': [236], 'by': [239, 312], 'Upon': [247], 'repeat': [248], 'stimulation,': [249], 'can': [255, 309], 'now': [256], 'IL-2-dependent': [260], 'manner': [261], 'when': [262], 'only': [265], 'anti-CD3': [266], 'mitogens,': [269], 'absence': [272], 'exogenous': [274], 'mAb.': [278], 'These': [279, 323], 'data': [280], 'show': [281], 'hyporesponsiveness': [284], 'result': [292], 'expression,': [298], 'it': [300, 308], 'fixed': [304], 'state,': [305], 'be': [310], 'reversed': [311], 'presence': [320], 'IL-2.': [322], 'observations': [324], 'extend': [325], 'between': [328]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1988363942', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}], 'updated_date': '2024-12-14T06:18:49.389003', 'created_date': '2016-06-24'}