Publication Information

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'abstract_inverted_index': {'Glutathione': [0, 292, 3661], '(GSH)': [1, 293, 699], 'depletion': [2, 25, 294, 317, 1220, 1285, 1457, 1722, 2029, 2762, 4275], 'is': [3, 28, 109, 158, 195, 295, 320, 401, 450, 487, 1221, 1244, 1288, 1584, 1692, 1834, 1892, 1944, 2056, 2092, 2114, 3952, 4186], 'the': [4, 105, 134, 145, 181, 190, 243, 281, 296, 397, 426, 437, 473, 482, 535, 573, 679, 695, 704, 1129, 1133, 1139, 1176, 1222, 1248, 1431, 1439, 1445, 1451, 1483, 1489, 1492, 1544, 1571, 1626, 1644, 1827, 1861, 1868, 1872, 1883, 1937, 1945, 1949, 2032, 2086, 2263, 2399, 2407, 2472, 2531, 2660, 2752, 2766, 2782, 2790, 2806, 2810, 2814, 2820, 2825, 2865, 2929, 2953, 2956, 2989, 3043, 3158, 3162, 3179, 3188, 3211, 3218, 3226, 3229, 3275, 3295, 3333, 3341, 3390, 3404, 3444, 3548, 3581, 3615, 3668, 3712, 3732, 3750, 3772, 3775, 3813, 3848, 3920, 3942, 3972, 4035, 4106, 4115, 4121, 4130, 4138, 4175, 4187, 4234, 4294, 4305, 4369, 4400, 4422], 'earliest': [5, 297, 1223], 'biochemical': [6, 298, 934, 1224], 'alteration': [7, 299, 1225], 'shown': [8, 38, 300, 330, 1226, 1825, 2147, 3927, 3997], 'to': [9, 31, 149, 213, 286, 301, 323, 441, 505, 578, 672, 1138, 1144, 1162, 1227, 1234, 1246, 1291, 1346, 1350, 1444, 1488, 1694, 1724, 1871, 2058, 2148, 2204, 2267, 2664, 2755, 2845, 2934, 2952, 3105, 3121, 3141, 3210, 3222, 3274, 3443, 3562, 3575, 3897, 3928, 3971, 4174, 4178, 4399, 4409, 4421], 'date': [10, 302, 1228], 'in': [11, 47, 133, 165, 189, 250, 253, 303, 339, 425, 457, 481, 542, 545, 678, 703, 1003, 1030, 1060, 1118, 1229, 1238, 1343, 1525, 1549, 1578, 1614, 1727, 1956, 2018, 2024, 2061, 2119, 2271, 2392, 2605, 2621, 2633, 2644, 2651, 2771, 2901, 2940, 2959, 2965, 3042, 3066, 3091, 3133, 3155, 3169, 3178, 3267, 3303, 3329, 3340, 3403, 3490, 3568, 3627, 3672, 3696, 3754, 3771, 3779, 3874, 3937, 3941, 3968, 4034, 4052, 4111, 4114, 4137, 4233, 4264, 4285, 4292, 4368], 'brains': [12, 304], 'of': [13, 42, 68, 147, 267, 276, 280, 283, 305, 334, 360, 439, 559, 568, 572, 575, 587, 665, 694, 707, 936, 1128, 1132, 1153, 1251, 1433, 1441, 1447, 1485, 1491, 1546, 1576, 1617, 1637, 1646, 1686, 1802, 1886, 1896, 2034, 2096, 2299, 2460, 2530, 2618, 2714, 2725, 2809, 2871, 2888, 2910, 2963, 2971, 2991, 3150, 3157, 3161, 3201, 3220, 3228, 3234, 3245, 3262, 3281, 3389, 3659, 3670, 3699, 3719, 3731, 3777, 3843, 3868, 3895, 3902, 3912, 3958, 3977, 4023, 4109, 4141, 4191, 4432], "Parkinson's": [14, 262, 306, 554, 591, 599], 'disease': [15, 307, 592], 'patients.': [16, 308], 'However,': [17, 309, 1277, 1430, 4020], 'data': [18, 310, 1278, 3993, 4057], 'from': [19, 160, 311, 452, 1279, 2090, 2315, 2326, 2334, 2345, 2356, 2363, 2395, 2422, 2428, 2442, 2465, 2469, 2494, 2503, 2516, 2524, 2536, 2544, 3239, 3828, 3890, 4282], 'animal': [20, 312, 1151, 1280], 'models': [21, 313, 1152, 1281], 'show': [22, 204, 241, 314, 496, 533, 1282, 2255], 'that': [23, 39, 99, 157, 161, 205, 227, 242, 315, 331, 391, 449, 453, 497, 519, 534, 1283, 1583, 1725, 1826, 1830, 1899, 2014, 2256], 'GSH': [24, 43, 199, 207, 255, 316, 335, 491, 499, 547, 1219, 1284, 1351, 1434, 1456, 1465, 1690, 1721, 1877, 2028, 2259, 2490, 2761, 2911, 2975, 3801, 3821, 3888, 4024, 4274], 'by': [26, 163, 198, 318, 455, 490, 1286, 1459, 1696, 1837, 1881, 1906, 1909, 2022, 2152, 2968, 2979, 3001, 3315, 3407, 3452, 3547, 3638, 3649, 3667, 3774, 3824, 3847, 3954, 3962, 4027, 4153, 4255, 4350, 4365, 4439], 'itself': [27, 319, 1287, 1907, 4028], 'not': [29, 123, 321, 415, 1289, 1835, 3994, 4030, 4050, 4182, 4277], 'sufficient': [30, 322, 1290], 'induce': [32, 222, 324, 514, 1292, 2031, 2268, 4031], 'nigral': [33, 325, 1293], 'degeneration.': [34, 326, 1164], 'We': [35, 327, 1607], 'have': [36, 328, 700, 1115, 1170, 1608, 1824], 'previously': [37, 329, 1610, 2561, 2627, 3926, 3998, 4055], 'non-toxic': [40, 332], 'inhibition': [41, 209, 333, 501, 2913, 4026, 4280], 'synthesis': [44, 208, 336, 500, 1466, 2912, 4025], 'with': [45, 66, 337, 358, 1809, 2279, 2291, 2303, 2416, 2610, 2629, 2729, 2789, 2851, 2859, 2982, 3003, 3011, 3020, 3062, 3075, 3087, 3137, 3187, 3198, 3206, 3318, 3337, 3448, 3487, 3585, 3619, 3693, 3716, 3737, 3804, 3840, 3882, 3919, 3979, 4054, 4236, 4272, 4298, 4312, 4338, 4377], 'l-buthionine-(S,R)-sulfoximine': [46, 338, 1460], 'primary': [48, 340, 1126, 3088], 'midbrain': [49, 341, 1355, 1579, 1624, 2272, 2548, 3483, 4061, 4287], 'cultures': [50, 151, 342, 443, 1149, 1580, 2063, 2543, 2641, 2856, 2981, 3059, 3484, 3877, 3913, 4062, 4266, 4295, 4401], 'transforms': [51, 343], 'a': [52, 63, 153, 223, 271, 344, 355, 445, 515, 563, 585, 1125, 1463, 1611, 1720, 1805, 2054, 2093, 2110, 2616, 2645, 2652, 2665, 2715, 3004, 3012, 3045, 3174, 3409, 3431, 3453, 3488, 3642, 3657, 3755, 3854, 3946, 3955, 3965, 3987, 4042, 4215, 4356, 4382], 'nitric': [53, 345, 610, 995], 'oxide': [54, 346, 996], '(NO)': [55, 347, 997], 'neurotrophic': [56, 348, 1800, 3930], 'effect,': [57, 349], 'selective': [58, 350, 1464, 4216], 'for': [59, 112, 211, 351, 404, 503, 1941, 2116, 2798, 2805, 2877, 2884, 2932, 3084, 3126, 3254, 3534, 3544, 3554, 3605, 3704, 3763, 3809, 3838, 3879, 3914, 3931, 4058, 4166, 4219, 4225, 4342], 'dopamine': [60, 352, 1340], 'neurons,': [61, 353], 'into': [62, 354, 1581], 'toxic': [64, 356, 669, 4173], 'effect': [65, 266, 357, 558, 1575, 2909], 'participation': [67, 359, 1885, 2962], 'guanylate': [69, 361, 619, 1812], 'cyclase': [70, 362, 1813], '(GC)': [71, 363, 1814], 'and': [72, 87, 120, 170, 173, 192, 233, 287, 364, 379, 412, 462, 465, 484, 525, 579, 849, 906, 994, 1085, 1150, 1173, 1524, 1568, 1639, 1657, 1815, 1879, 1948, 1959, 2052, 2109, 2258, 2294, 2311, 2322, 2328, 2412, 2435, 2455, 2457, 2462, 2489, 2500, 2513, 2557, 2722, 2745, 2760, 2779, 2818, 2824, 2829, 2853, 2928, 2993, 3018, 3056, 3079, 3099, 3124, 3135, 3204, 3242, 3252, 3294, 3332, 3385, 3428, 3516, 3521, 3527, 3553, 3572, 3600, 3623, 3647, 3711, 3723, 3744, 3749, 3798, 3812, 3947, 3975, 3988, 3990, 3992, 4043, 4144, 4149, 4160, 4245, 4302, 4331, 4353, 4379, 4391], 'cGMP-dependent': [73, 365, 622], 'protein': [74, 366, 623, 1818, 2401, 2520, 3545, 3550, 3896, 3903], 'kinase': [75, 367, 1819], '(PKG)': [76, 368, 1820], '(Canals,': [77, 369], 'S.,': [78, 84, 370, 376], 'Casarejos,': [79, 371], 'M.': [80, 89, 372, 381, 859, 974, 1405, 2237, 2239, 3027], 'J.,': [81, 373], 'de': [82, 374, 1590, 1666, 1703, 1843, 2126, 2568, 2679, 3465, 4003, 4067], 'Bernardo,': [83, 375], 'Rodríguez-Martín,': [85, 377], 'E.,': [86, 378], 'Mena,': [88, 380], 'A.': [90, 382, 968, 985, 1017, 1066, 1193, 1302, 1506, 2184, 2213, 3373], '(2001)': [91, 383], 'J.': [92, 384, 740, 751, 795, 819, 839, 896, 1073, 1267, 1328, 1364, 1388, 1414, 1470, 1533, 1558, 1597, 1671, 1710, 1759, 1770, 1850, 1924, 1983, 2040, 2133, 2162, 2167, 2190, 2219, 2220, 2241, 2377, 3417, 3470, 4010, 4074, 4094], 'Neurochem.': [93, 385, 741, 796, 820, 840, 897, 1268, 1365, 1389, 1534, 1559, 1598, 1672, 1711, 1760, 1851, 1925, 2134, 3471, 4011, 4075, 4095], '79,': [94, 386], '1183–1195).': [95, 387], 'Here': [96, 388, 2253], 'we': [97, 203, 240, 389, 495, 532, 1823, 1864, 2254, 4118, 4212], 'demonstrate': [98, 390], 'arachidonic': [100, 392, 626, 1887], 'acid': [101, 119, 393, 411, 1888, 2510, 3077, 3702, 3796, 4415], '(AA)': [102, 394, 1889], 'metabolism': [103, 395, 1943, 2151], 'through': [104, 180, 396, 472, 1912], '12-lipoxygenase': [106, 398, 2342], '(12-LOX)': [107, 399], 'pathway': [108, 245, 273, 400, 537, 565, 2266, 2816, 2822, 2827], 'also': [110, 228, 402, 520, 2904, 2918], 'central': [111, 403], 'this': [113, 237, 405, 529, 1682, 2943, 3258, 4021, 4192], 'GSH-NO': [114, 406], 'interaction.': [115, 407], 'LOX': [116, 408, 2815, 4123], 'inhibitors': [117, 409, 2804, 2947, 4249], '(nordihydroguaiaretic': [118, 410], 'baicalein),': [121, 413, 2819], 'but': [122, 414], 'cyclooxygenase': [124, 416, 1915], '(indomethacin)': [125, 417], 'or': [126, 418, 1136, 1908, 1917, 2200, 2478, 2487, 2538, 2623, 2777, 2795, 2831, 2843, 2875, 2892, 2900, 2948, 2984, 4045, 4329, 4407], 'epoxygenase': [127, 419, 1918, 2826], '(clotrimazole)': [128, 420], 'ones,': [129, 421], 'prevent': [130, 422], 'cell': [131, 154, 187, 224, 290, 423, 446, 479, 516, 582, 1140, 1148, 1356, 1807, 1832, 2019, 2117, 2269, 2480, 2764, 2915, 3396, 3449, 3939, 4032, 4112, 4135, 4220, 4252, 4347, 4362, 4386, 4435], 'death': [132, 155, 188, 225, 424, 447, 480, 517, 1141, 1808, 1833, 2020, 2060, 2118, 2270, 3397, 3450, 3940, 3950, 4033, 4113, 4253], 'culture,': [135, 191, 427, 483, 2772, 3044], 'even': [136, 428, 1569], 'when': [137, 429, 1689, 3863], 'added': [138, 430, 2837, 2951, 3118, 3251, 3273, 3339, 3561, 4398, 4420], '10': [139, 431, 2846, 3497, 4410, 4424], 'h': [140, 432, 2847, 3086, 3280, 3607, 3881, 3918, 4039, 4048, 4411, 4425, 4431], 'after': [141, 433, 2658, 2768, 3278, 3794, 4426], 'NO': [142, 164, 268, 434, 456, 560, 1027, 1577, 1629, 1687, 1803, 1838, 1880, 2023, 2144, 2257, 2759, 2791, 2972, 3921, 4131], 'treatment.': [143, 435, 4428], 'Furthermore,': [144, 436, 1165, 1339], 'addition': [146, 202, 438, 494, 2990], 'AA': [148, 178, 440, 470, 1891, 1942, 2088, 2150, 2202, 2264, 2463, 2811, 2852], 'GSH-depleted': [150, 442, 2062, 3875, 3909], 'precipitates': [152, 444], 'process': [156, 226, 448, 518, 1142, 1178, 3951], 'indistinguishable': [159, 451], 'initiated': [162, 454], 'its': [166, 193, 458, 485, 1910, 2832, 3887], 'morphology,': [167, 459], 'time': [168, 460, 2885], 'course,': [169, 461], '12-LOX,': [171, 231, 463, 523, 628, 2091], 'GC,': [172, 232, 464, 524, 618], 'PKG': [174, 234, 466, 526], 'dependence.': [175, 467], 'The': [176, 264, 468, 556, 2518, 2601, 2640, 2906, 2920, 2961, 3148, 3165, 3214, 3540, 3634, 3949, 4163], 'first': [177, 469, 4119], 'metabolite': [179, 471, 2089], '12-LOX': [182, 474, 1946, 2015, 2035, 2854, 2897, 2964, 4185, 4217], 'enzyme,': [183, 475], '12-hydroperoxyeicosatetraenoic': [184, 476], 'acid,': [185, 477], 'induces': [186, 478], 'toxicity': [194, 486, 1446, 1490, 1545, 4284], 'greatly': [196, 488, 1174], 'enhanced': [197, 489], 'depletion.': [200, 492], 'In': [201, 236, 493, 528, 584, 932, 1147, 1623, 1795, 1860, 1934, 2942, 3438, 3907, 4388], 'if': [206, 498], 'persists': [210, 502], 'up': [212, 504, 2844, 2933, 4177, 4408], '4': [214, 506, 2769, 2935, 3082, 3538, 3632, 3708, 3717, 4290], 'days': [215, 507, 2770, 2936, 4291], 'without': [216, 508, 3982, 4270], 'any': [217, 509], 'additional': [218, 510, 2800, 2879, 3916], 'treatment,': [219, 511, 1462, 4132], 'it': [220, 512], 'will': [221, 513], 'depends': [229, 521], 'on': [230, 522, 1811, 2763, 2781, 2864, 2896, 2914, 2955, 3194, 3324, 3387, 4304], 'activation.': [235, 527, 1821], 'study,': [238, 530], 'therefore,': [239, 531], 'signaling': [244, 272, 536, 564, 1903, 1958], 'AA/12-LOX/12-HPETE/GC/PKG': [246, 538], 'may': [247, 274, 539, 566, 675, 1160, 1436, 2016], 'be': [248, 275, 540, 567, 1145, 1247, 1347, 3929], 'important': [249, 541, 1894, 1954], 'several': [251, 543, 667, 1154, 1902, 2869], 'pathologies': [252, 544], 'which': [254, 546, 1243, 1615, 2300], 'decrease': [256, 548, 1352], 'has': [257, 549, 2145], 'been': [258, 550, 701, 1116, 1171, 2146], 'documented,': [259, 551], 'such': [260, 270, 552, 562, 1122, 2053], 'as': [261, 278, 553, 570, 776, 778, 2559, 2670, 2861, 2926, 3430, 3656, 3818, 3853, 3996, 4258, 4260, 4355, 4381], 'disease.': [263, 555], 'potentiating': [265, 557], 'over': [269, 561], 'relevance': [277, 569], 'part': [279, 571, 1131], 'cascade': [282, 574], 'events': [284, 576], 'leading': [285, 577], 'sustaining': [288, 580], 'nerve': [289, 581], 'death.': [291, 583], 'number': [586, 1645, 3149], 'neurological': [588], 'disorders,': [589], 'including': [590, 1156], '(PD),': [593], '1The': [594], 'abbreviations': [595], 'used': [596, 3543, 4120], 'are:': [597], 'PD,': [598, 1157], 'disease;': [600], 'DA,': [601], 'dopamine;': [602], 'BSO,': [603, 2450, 4301], 'l-buthionine-(S,R)-sulfoximine;': [604], 'MPTP,': [605], '1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;': [606], 'MPP+,': [607], '1-methyl-4-phenylpyridinum;': [608], 'NO,': [609], 'oxide;': [611], 'DEA/NO,': [612], 'diethylamine/NO-complexed': [613], 'sodium;': [614], 'TH,': [615, 3054], 'tyrosine': [616, 1647], 'hydroxylase;': [617], 'cyclase;': [620], 'PKG,': [621], 'kinase;': [624], 'AA,': [625, 2872], 'acid;': [627, 634, 637, 648], '12-lipoxygenase;': [629], 'COX,': [630], 'cyclooxygenase;': [631], '12-HETE,': [632, 2499, 2874], '(12S)-hydroxyeicosatetraenoic': [633], '12-HPETE,': [635, 2085, 2498, 2873], '(12S)-hydroperoxyeicosatetraenoic': [636], 'PLA,': [638], 'phospholipase;': [639], 'LDH,': [640], 'lactate': [641], 'dehydrogenase;': [642], 'MTT,': [643], '3-(4,5-dimethylthiazol-2-yl)-2,5-di-phenyltetrazolium': [644], 'bromide;': [645], 'NDGA,': [646, 4226], 'nordihydroguaiaretic': [647, 2509], 'GFAP,': [649, 3055], 'glial': [650], 'fibrillary': [651], 'acidic': [652], 'protein;': [653, 656], 'MAP,': [654], 'microtubule-associated': [655], 'PBS,': [657, 3134, 3694], 'phosphate-buffered': [658, 3069], 'saline;': [659], 'DTNB,': [660, 2454], '5,5′-dithiobis(2-nitrobenzoic': [661], 'acid);': [662], 'ANOVA,': [663], 'analysis': [664, 3842], 'variance.': [666], 'potentially': [668], 'alterations': [670, 1123, 1159], 'related': [671, 1870, 2057], 'oxidative': [673], 'stress': [674], 'coexist': [676], 'simultaneously': [677], 'brain': [680, 4189], '(1Jenner': [681, 1179], 'P.': [682, 727, 763, 782, 816, 836, 893, 954, 1013, 1068, 1180, 1254, 1325, 1746, 1782, 1964, 2067, 4197], 'Olanow': [683, 1071, 1181, 4092], 'C.W.': [684, 1072, 1182, 4093], 'Neurology.': [685, 1183], '1996;': [686, 986, 1049, 1184, 1312, 1516, 2223, 2245], '47:': [687, 1185], 'S161-S170Crossref': [688, 1186], 'PubMed': [689, 721, 745, 771, 800, 824, 844, 879, 901, 926, 962, 989, 1022, 1052, 1080, 1110, 1187, 1272, 1315, 1334, 1369, 1393, 1425, 1479, 1519, 1538, 1563, 1602, 1676, 1715, 1740, 1764, 1790, 1855, 1929, 1974, 1989, 2006, 2049, 2079, 2138, 2178, 2195, 2231, 2248, 2383, 2575, 2596, 2686, 2707, 3033, 3365, 3380, 3423, 3475, 3681, 3788, 4015, 4079, 4099, 4207], 'Google': [690, 724, 748, 774, 803, 827, 847, 882, 904, 929, 965, 992, 1025, 1055, 1083, 1113, 1188, 1204, 1217, 1275, 1318, 1337, 1372, 1396, 1428, 1480, 1522, 1541, 1566, 1605, 1679, 1718, 1743, 1767, 1793, 1858, 1932, 1977, 1992, 2009, 2050, 2082, 2107, 2141, 2181, 2198, 2234, 2251, 2386, 2578, 2599, 2689, 2710, 3036, 3368, 3383, 3426, 3478, 3684, 3791, 4018, 4082, 4102, 4210], 'Scholar).': [691, 1218, 1276, 1338, 1429, 1606, 1680, 1794, 1859, 1933, 2010, 2083, 2142, 2252, 2600, 2711, 3037, 3479, 3685, 3792, 4019, 4103], 'Decreased': [692], 'levels': [693, 1435, 1878, 3664, 3827], 'thiolic': [696], 'antioxidant': [697], 'glutathione': [698, 2461, 3663, 3745, 3767, 3830], 'reported': [702, 2671, 4056], 'substantia': [705], 'nigra': [706, 1032], 'PD': [708, 1031, 1119, 1230, 1252, 1728], 'patients': [709], '(2Perry': [710, 1729], 'T.L.': [711, 1730], 'Godin': [712, 1731], 'D.V.': [713, 1732], 'Hansen': [714, 1733], 'S.': [715, 857, 861, 912, 920, 984, 1009, 1191, 1321, 1383, 1407, 1587, 1592, 1661, 1668, 1700, 1705, 1734, 1840, 1845, 1995, 2123, 2128, 2209, 2371, 3460, 3467, 4000, 4005, 4064, 4069], 'Neurosci.': [716, 1197, 1210, 1735, 1984], 'Lett.': [717, 1736], '1982;': [718, 1473, 1737], '33:': [719, 1738], '305-310Crossref': [720, 1739], 'Scopus': [722, 746, 772, 801, 825, 845, 880, 902, 927, 963, 990, 1023, 1053, 1081, 1111, 1202, 1215, 1273, 1316, 1335, 1370, 1394, 1426, 1520, 1539, 1564, 1603, 1677, 1716, 1741, 1765, 1791, 1856, 1930, 1975, 1990, 2007, 2080, 2139, 2179, 2196, 2232, 2249, 2384, 2576, 2597, 2687, 2708, 3034, 3366, 3381, 3424, 3476, 3682, 3789, 4016, 4080, 4100, 4208], '(667)': [723, 1742], 'Scholar,': [725, 749, 804, 828, 883, 966, 1189, 1205, 1319, 1373, 1397, 1744, 1768, 1978, 1993, 2182, 2235, 2579, 2690, 3369, 4083], '3Riederer': [726, 1745], 'Sofic': [728, 783, 1255, 1747], 'E.': [729, 784, 830, 1256, 1553, 1594, 1665, 1707, 1748, 1847, 2130, 3464, 4007, 4071], 'Rausch': [730, 785, 1257, 1749], 'W.-D.': [731, 786, 1258, 1750], 'Schmidt': [732, 787, 1259, 1751], 'B.': [733, 788, 1260, 1557, 1752, 2099, 2565, 2581, 2676, 2692, 3350], 'Reynolds': [734, 789, 1261, 1753], 'G.P.': [735, 790, 1262, 1754], 'Jellinger': [736, 791, 833, 1263, 1755], 'K.': [737, 792, 834, 863, 972, 1264, 1359, 1375, 1399, 1528, 1756], 'Youdim': [738, 793, 837, 1265, 1757], 'M.B.H.': [739, 794, 838, 1266, 1758], '1989;': [742, 797, 821, 876, 1269, 1560, 1761], '52:': [743, 798, 822, 1270, 1561, 1762], '515-520Crossref': [744, 799, 1271, 1763], '(1240)': [747, 802, 1274, 1766], '4Sian': [750, 1769], 'Dexter': [752, 888, 1771], 'D.T.': [753, 806, 889, 940, 1772], 'Lees': [754, 809, 951, 1773], 'A.J.': [755, 810, 952, 1774], 'Daniel': [756, 949, 1775], 'S.E.': [757, 950, 1776], 'Agid': [758, 811, 813, 1777], 'Y.': [759, 814, 855, 871, 910, 978, 1778, 2065], 'Javoy-Agid': [760, 1779], 'F.': [761, 812, 1306, 1510, 1780, 3675], 'Jenner': [762, 815, 892, 953, 1324, 1781], 'Marsden': [764, 817, 894, 955, 1326, 1783], 'C.D.': [765, 818, 895, 956, 1327, 1784, 2164], 'Ann.': [766, 921, 1785], 'Neurol.': [767, 922, 1076, 1786], '1994;': [768, 923, 959, 1787, 1986], '36:': [769, 1788, 2004], '348-355Crossref': [770, 1789], '(970)': [773, 1792], 'Scholar),': [775, 1026, 1056, 1084, 1481, 1542, 1567, 1719, 2051, 2108, 4211], 'well': [777, 4259], 'iron': [779], 'accumulation': [780], '(3Riederer': [781, 1253], '5Dexter': [805], 'Wells': [807, 947], 'F.R.': [808, 948], '1830-1836Crossref': [823], '(952)': [826], '6Sofic': [829], 'Pavón': [831], 'N.': [832, 918, 970, 1999], 'Riederer': [835], '1991;': [841, 2104], '56:': [842], '978-982Crossref': [843], '(459)': [846], 'Scholar)': [848, 905, 930, 993, 1114, 1523, 2199, 3384, 3427], 'decreased': [850, 1876, 3886], 'mitochondrial': [851, 1493, 3959], 'complex': [852, 1494], 'I': [853, 1495, 2483], '(7Mizuno': [854], 'Ohta': [856], 'Tanaka': [858, 973], 'Takamiya': [860], 'Suzuki': [862, 1996], 'Sato': [864], 'T.': [865, 869, 1310, 1379, 1514, 1555, 1921, 3414, 4091], 'Oya': [866], 'H.': [867, 914, 916, 1101, 1997], 'Ozawa': [868], 'Kagawa': [870], 'Biochem.': [872, 1045, 3677, 3784], 'Biophys.': [873, 1046], 'Res.': [874, 1047, 1198, 1211, 1985, 2002, 2379, 2589, 2591, 2700, 2702, 3358, 3360, 3376], 'Commun.': [875, 1048], '163:': [877], '1450-1455Crossref': [878], '(658)': [881], '8Schapira': [884], 'A.H.': [885, 1044], 'Cooper': [886, 1037, 1039], 'J.M.': [887, 1040, 1097], 'Clark': [890], 'J.B.': [891, 1300, 1504], '1990;': [898, 1926, 1968, 4201], '54:': [899], '823-827Crossref': [900], '(1681)': [903], 'α-ketoglutarate': [907], 'dehydrogenase': [908], '(9Mizuno': [909], 'Matuda': [911], 'Yoshino': [913], 'Mori': [915], 'Hattori': [917, 969], 'Ikebe': [919], '35:': [924], '204-210Crossref': [925], '(178)': [928], 'activities.': [931], 'addition,': [933, 1796, 4434], 'markers': [935], 'lipid': [937], 'peroxidation': [938], '(10Dexter': [939], 'Holley': [941], 'A.E.': [942, 2160], 'Flitter': [943], 'W.D.': [944], 'Slater': [945], 'T.F.': [946], 'Mov.': [957], 'Disord.': [958], '9:': [960], '92-97Crossref': [961], '(391)': [964], '11Yoritaka': [967], 'Uchida': [971], 'Stadman': [975], 'E.R.': [976], 'Mizuno': [977], 'Proc.': [979], 'Natl.': [980], 'Acad.': [981], 'Sci.': [982, 1967, 4200], 'U.': [983, 1296, 1500], '93:': [987], '2696-2701Crossref': [988], '(877)': [991], 'overproduction,': [998], 'i.e.': [999, 2813], 'increased': [1000, 1057], 'nitrite': [1001], 'concentration': [1002, 4164], 'cerebrospinal': [1004], 'fluid': [1005], '(12Qureshi': [1006], 'G.A.': [1007], 'Baig': [1008], 'Bednar': [1010], 'I.': [1011, 3025, 3371], 'Sodersten': [1012], 'Forsberg': [1014], 'G.': [1015], 'Siden': [1016], 'Neuroreport.': [1018, 1311, 1515, 2571, 2682], '1995;': [1019, 2170], '6:': [1020], '1642-1644Crossref': [1021], '(138)': [1024], 'radicals': [1028], 'detected': [1029], '(13Shergill': [1033], 'J.K.': [1034], 'Cammack': [1035], 'R.': [1036, 1304, 1508, 2373], 'C.E.': [1038], 'Mann': [1041], 'V.M.': [1042], 'Schapira': [1043], '228:': [1050], '298-305Crossref': [1051], '(52)': [1054], '3-nitrotyrosine': [1058], 'immunostaining': [1059, 3002], 'Lewy': [1061, 1240], 'bodies': [1062, 1241], '(14Good': [1063], 'P.F.': [1064], 'Hsu': [1065], 'Werner': [1067], 'Perl': [1069], 'D.P.': [1070], 'Neuropathol.': [1074, 2244], 'Exp.': [1075, 3374], '1998;': [1077], '57:': [1078], '338-342Crossref': [1079], '(518)': [1082], 'α-synuclein': [1086], 'nitration': [1087], '(15Giasson': [1088], 'B.I.': [1089], 'Duda': [1090], 'J.E.': [1091], 'Murray': [1092], 'I.V.J.': [1093], 'Chen': [1094], 'Q.': [1095], 'Souza': [1096], 'Hurtig': [1098], 'H.I.': [1099], 'Ischiropoulos': [1100], 'Trojanowski': [1102], 'J.Q.': [1103], 'Lee': [1104], 'V.M.-Y.': [1105], 'Science.': [1106, 2337, 2497], '2000;': [1107, 1390, 2192], '290:': [1108], '985-989Crossref': [1109], '(1396)': [1112], 'found': [1117], 'brains.': [1120, 1231], 'Whether': [1121], 'are': [1124], 'cause': [1127], 'disease,': [1130, 1242], 'degenerative': [1134], 'mechanism,': [1135], 'secondary': [1137, 3101], 'remains': [1143], 'resolved.': [1146], 'diseases,': [1155], 'these': [1158, 1618, 3908], 'contribute': [1161], 'neuronal': [1163, 1957, 2059, 4059], 'synergistic': [1166], 'interactions': [1167, 1619, 2757], 'between': [1168, 1875, 2758], 'them': [1169], 'demonstrated': [1172], 'enhance': [1175, 1438], 'neurodegenerative': [1177, 1452], '16Hunot': [1190], 'Hartmann': [1192], 'Hirsch': [1194], 'E.C.': [1195], 'Clin.': [1196, 1209], '2001;': [1199, 1212, 1417, 1599, 1673, 1712, 1852, 2135, 3472, 4012, 4076], '1:': [1200, 1213, 2594, 2705, 3363], '434-443Crossref': [1201], '(39)': [1203], '17Di': [1206], 'Monte': [1207], 'D.A.': [1208, 1377], '419-426Crossref': [1214], '(29)': [1216], 'It': [1232], 'seems': [1233], 'appear': [1235], 'before': [1236, 2840, 2988, 4129, 4404], 'neurodegeneration': [1237], 'incidental': [1239], 'considered': [1245, 3860], 'presymptomatic': [1249], 'manifestation': [1250], 'degeneration': [1294, 1960], '(18Wullner': [1295, 1499], 'Loschmann': [1297, 1501], 'P.A.': [1298, 1502], 'Schulz': [1299, 1503], 'Schmid': [1301, 1505], 'Dringen': [1303, 1507], 'Eblen': [1305, 1509], 'Turski': [1307, 1511], 'L.': [1308, 1512, 2186], 'Klockgether': [1309, 1513], '7:': [1313, 1517], '921-923Crossref': [1314, 1518], '(143)': [1317, 1521], '19Toffa': [1320], 'Kunikowska': [1322], 'G.M.': [1323], 'Neural': [1329], 'Transm.': [1330], '1997;': [1331, 1366, 1535, 2003, 2071, 2593, 2704, 3362], '104:': [1332], '67-75Crossref': [1333], '(74)': [1336], '(DA)': [1341], 'neurons': [1342, 1487, 2998, 3041, 3933], 'culture': [1344, 1612, 2954, 3196, 3235, 3405, 3445, 3943, 3973, 4036, 4139, 4176, 4235, 4370, 4423], 'seem': [1345], 'more': [1348], 'resistant': [1349], 'than': [1353], 'other': [1354, 1448, 2527], 'populations': [1357], '(20Nakamura': [1358, 1527], 'Wang': [1360, 1529, 2161], 'W.': [1361, 1530], 'Kuang': [1362, 1531], 'U.J.': [1363, 1387, 1413, 1532], '69:': [1367, 1536], '1850-1858Crossref': [1368, 1537], '(78)': [1371, 1540], '21Nakamura': [1374], 'Wright': [1376], 'Wiatr': [1378], 'Kowlessur': [1380, 1402], 'D.': [1381, 1403, 1962, 2069, 4195], 'Milstien': [1382, 1406], 'Lei': [1384], 'X.G.': [1385], 'Kang': [1386, 1412], '74:': [1391], '2305-2314Crossref': [1392], '(40)': [1395], '22Nakamura': [1398], 'Bindokas': [1400], 'V.P.': [1401], 'Elas': [1404], 'Marks': [1408], 'J.D.': [1409], 'Halpern': [1410], 'H.J.': [1411], 'Biol.': [1415, 1471, 2041, 2168, 2221, 3029], 'Chem.': [1416, 1472, 2042, 2169, 2222, 2243], '276:': [1418], '34402-34407Abstract': [1419], 'Full': [1420, 1422, 1476, 1971, 2046, 2074, 2076, 2173, 2175, 2226, 2228, 4204], 'Text': [1421, 1423, 1477, 1972, 2047, 2075, 2077, 2174, 2176, 2227, 2229, 4205], 'PDF': [1424, 1478, 1973, 2048, 2078, 2177, 2230, 4206], '(83)': [1427], 'reduction': [1432], 'rather': [1437], 'susceptibility': [1440, 1484], 'DA': [1442, 1486, 1572, 1655, 1683, 3932], 'cells': [1443, 2602, 2661, 2921, 3108, 3123, 3152, 3166, 3221, 3690, 3773, 3978], 'insults,': [1449], 'promoting': [1450], 'process.': [1453], 'For': [1454, 2849, 3053, 3112, 3394, 3579], 'example,': [1455], 'induced': [1458, 2967, 4152, 4254], '(BSO)': [1461], 'inhibitor': [1467, 1496, 4124], '(23Griffith': [1468], 'O.W.': [1469, 3782], '257:': [1474], '13704-13712Abstract': [1475], 'enhances': [1482], 'MPTP/MPP+in': [1497], 'vivo': [1498], 'vitro': [1526], 'potentiates': [1543], '6-hydroxydopamine': [1547], '(6-OHDA)': [1548], 'rat': [1550, 2547], 'striatum': [1551], '(24Pileblad': [1552], 'Magnusson': [1554], 'Fornstedt': [1556], '978-984Crossref': [1562], '(88)': [1565], 'changes': [1570], 'cell-specific': [1573, 1684], 'trophic': [1574], 'one': [1582, 1616], 'neurotoxic': [1585, 1873], '(25Canals': [1586, 1699, 1839, 2122, 3999, 4063], 'Casarejos': [1588, 1662, 1701, 1841, 2124, 2584, 2695, 3353, 3461, 4001, 4065], 'M.J.': [1589, 1663, 1702, 1842, 2039, 2125, 2166, 2585, 2696, 3354, 3462, 4002, 4066], 'Bernardo': [1591, 1667, 1704, 1844, 2127, 3466, 4004, 4068], 'Rodríguez-Martín': [1593, 1664, 1706, 1846, 2129, 3463, 4006, 4070], 'Mena': [1595, 1669, 1708, 1848, 2131, 2586, 2697, 3355, 3468, 4008, 4072], 'M.A.': [1596, 1670, 1709, 1849, 2132, 2563, 2587, 2674, 2698, 3356, 3469, 4009, 4073], '79:': [1600, 1713, 1853, 2136, 4013, 4077], '1183-1195Crossref': [1601, 1714, 1854, 2137, 4014, 4078], '(62)': [1604, 1717, 1857, 2140, 3382, 4017, 4081], 'described': [1609, 2560, 3819], 'model': [1613, 2121], 'was': [1620, 2333, 2344, 2355, 2361, 2394, 2427, 2441, 2468, 2523, 2917, 2977, 3051, 3117, 3153, 3185, 3301, 3313, 3401, 3542, 3654, 3752, 3769, 3802, 3815, 3822, 4169, 4397, 4419, 4437], 'clearly': [1621], 'stated.': [1622], 'cultures,': [1625], 'short': [1627], 'lived': [1628], 'donor': [1630, 2792, 3922], 'diethyl-amine/nitric': [1631], 'oxide-complexed': [1632], 'sodium': [1633, 2309, 2323, 2746], '(DEA/NO),': [1634], 'at': [1635, 2262, 2615, 2648, 3081, 3129, 3283, 3298, 3530, 3537, 3608, 3631, 3707, 3760, 3806, 3924, 4037, 4046, 4240], 'doses': [1636, 1801, 2870, 2970, 3925], '25': [1638], '50': [1640, 4256], 'μm,': [1641, 4171], 'selectively': [1642], 'increases': [1643], 'hydroxylase': [1648, 2352], 'positive': [1649, 3107], '(TH+)': [1650], 'cells,': [1651, 2767], 'TH+': [1652], 'neurite': [1653], 'processes,': [1654], 'syntheses,': [1656], '[3H]DA': [1658], 'uptake': [1659], '(26Canals': [1660, 3459], '76:': [1674, 3473], '56-68Crossref': [1675, 3474], '(49)': [1678, 3477], 'Interestingly,': [1681], 'neurotropism': [1685], 'disappears': [1688], 'content': [1691, 3889], 'lowered': [1693], '50%': [1695], 'BSO': [1697, 2776, 2860, 2895, 2925, 3885, 4154], 'pretreatment': [1698], 'similar': [1723], 'occurring': [1726], 'under': [1797, 2973, 3109], 'GSH-decreased': [1798, 2025, 4286], 'conditions,': [1799, 3910, 4117], 'trigger': [1804], 'programmed': [1806], 'dependence': [1810], 'cyclic': [1816], 'GMP-dependent': [1817], 'Also,': [1822], 'GC': [1828, 2097, 2112], 'activation': [1829, 2033, 2113], 'mediates': [1831], 'produced': [1836], 'present': [1862], 'work': [1863], 'go': [1865], 'far': [1866], 'inside': [1867], 'mechanism': [1869, 2055], 'interaction': [1874], 'exploring': [1882], 'possible': [1884, 4107], 'metabolism.': [1890], 'an': [1893, 1953, 2799, 2878, 3304, 3915], 'component': [1895], 'membrane': [1897, 2205], 'lipids': [1898], 'can': [1900, 2030], 'activate': [1901], 'pathways': [1904, 1919, 2808], 'directly': [1905, 3119], 'metabolites': [1911, 1951], 'lipoxygenase': [1913, 4110], '(LOX),': [1914], '(COX),': [1916], '(27Shimizu': [1920], 'Wolfe': [1922], 'L.S.': [1923], '55:': [1927], '1-15Crossref': [1928], '(536)': [1931], 'nervous': [1935], 'tissue,': [1936], 'major': [1938], 'enzymatic': [1939], 'route': [1940], 'pathway,': [1947], 'resulting': [1950, 3733], 'play': [1952], 'role': [1955, 4108], '(28Piomelli': [1961, 4194], 'Greengard': [1963, 4196], 'Trends': [1965, 4198], 'Pharmacol.': [1966, 2103, 2191, 4199], '11:': [1969, 4202], '367-373Abstract': [1970, 4203], '(182)': [1976, 4209], '29Farooqui': [1979], 'A.A.': [1980], 'Horrocks': [1981], 'L.A.': [1982], '38:': [1987], '6-11Crossref': [1988], '(66)': [1991], '30Yamamoto': [1994], 'Ueda': [1998], 'Prog.': [2000], 'Lipid': [2001], '23-41Crossref': [2005], '(101)': [2008], 'Several': [2011], 'observations': [2012], 'suggest': [2013], 'participate': [2017], 'triggered': [2021], 'conditions.': [2026], 'First,': [2027], '(31Shornick': [2036], 'L.P.': [2037], 'Holtzman': [2038], '1993;': [2043, 2572, 2683], '268:': [2044], '371-376Abstract': [2045], '(32Li': [2064], 'Maher': [2066], 'Schubert': [2068], 'Neuron.': [2070], '19:': [2072], '453-463Abstract': [2073], '(424)': [2081], 'Second,': [2084], 'initial': [2087], 'potent': [2094], 'activator': [2095], '(33Brüne': [2098], 'Ullrich': [2100], 'V.': [2101], 'Mol.': [2102, 2242], '39:': [2105], '671-678PubMed': [2106], 'NO-independent': [2111], 'necessary': [2115], 'our': [2120, 3439], 'Finally,': [2143, 2882], 'potentiate': [2149], 'activating': [2153], 'phospholipase': [2154], '(PLA)': [2155], 'A2': [2156], '(34Gross': [2157], 'R.W.': [2158, 2215], 'Rudolph': [2159], 'Sommers': [2163], 'Wolf': [2165], '270:': [2171], '14855-14858Abstract': [2172], '(58)': [2180], '35Guidarelli': [2183], 'Palomba': [2185], 'Cantoni': [2187], 'O.': [2188], 'Br.': [2189], '129:': [2193], '1539-1541Crossref': [2194], '(28)': [2197], 'inhibiting': [2201], 're-esterification': [2203], '(36Ma': [2206], 'Z.': [2207], 'Ramanadham': [2208], 'Corbett': [2210], 'J.A.': [2211], 'Bohrer': [2212], 'Gross': [2214], 'McDaniel': [2216], 'M.L.': [2217, 3416], 'Turk': [2218], '271:': [2224], '1029-1042Abstract': [2225], '(57)': [2233], '37Samochocki': [2236], 'Chalimoniuk': [2238], 'Strosznajder': [2240], '29:': [2246], '79-92Crossref': [2247], '(7)': [2250], 'synergically': [2260], 'interact': [2261], 'metabolic': [2265], 'cultures.': [2273, 4288], 'Culture': [2274], "Media—Dulbecco's": [2275], 'modified': [2276, 2607], "Eagle's": [2277, 2287, 2608, 2718], 'medium': [2278, 2290, 2609, 2668, 2721, 3203, 3236, 3406, 3446], 'high': [2280], 'glucose': [2281], '(4.5g/liter),': [2282], "Ham's": [2283, 2726], 'F12': [2284], 'nutrient': [2285, 2723], 'mixture,': [2286], 'minimal': [2288, 2719], 'essential': [2289, 2720], "Earl's": [2292], 'salts,': [2293], "Leibovitz's": [2295], 'l-15': [2296], 'medium,': [2297, 3974], 'all': [2298, 3040, 4229], 'were': [2301, 2313, 2325, 2420, 2464, 2493, 2502, 2515, 2529, 2555, 2603, 2642, 2662, 2787, 2835, 2857, 2903, 2950, 2999, 3060, 3103, 3167, 3192, 3237, 3250, 3271, 3288, 3327, 3335, 3485, 3560, 3583, 3617, 3636, 3665, 3691, 3714, 3735, 3835, 3859, 4296, 4310, 4336], 'supplemented': [2302, 2728], 'l-glutamine,': [2304, 2312], 'fetal': [2305, 2612, 3095], 'calf': [2306, 2613, 3096], 'serum': [2307, 2614], '(FCS),': [2308], 'pyruvate,': [2310], 'purchased': [2314, 2421], 'Invitrogen.': [2316], 'Glucose': [2317], '(45%),': [2318], 'insulin,': [2319], 'putrescine,': [2320], 'progesterone,': [2321], 'selenite': [2324, 2747], 'Sigma,': [2327], 'human': [2329], 'transferrin': [2330, 2736], '(30%': [2331], 'iron-saturated)': [2332], 'Roche': [2335, 2495], 'Applied': [2336, 2496], 'Antibodies—Rabbit': [2338], 'polyclonal': [2339, 2388, 3014], 'anti-mouse': [2340, 2424, 2436, 3142], 'leukocyte': [2341], 'antibody': [2343, 2354, 3008, 3016, 3049, 3116], 'Alexis': [2346], '(Carlsbad,': [2347], 'CA);': [2348, 2359], 'mouse': [2349, 2408, 3005, 3046, 3624], 'monoclonal': [2350, 2409, 3006, 3021, 3047], 'anti-tyrosine': [2351], '(TH)': [2353], 'Chemicon': [2357], '(Temecula,': [2358], 'O1': [2360], 'obtained': [2362, 2556, 3823], 'hybridoma': [2364], 'supernatants': [2365, 3713, 3734], '(38Raff': [2366], 'M.C.': [2367], 'Fields': [2368], 'K.L.': [2369], 'Hakomori': [2370], 'Mirsky': [2372], 'Pruss': [2374], 'R.M.': [2375], 'Winter': [2376], 'Brain': [2378, 2588, 2590, 2699, 2701, 3357, 3359], '1979;': [2380], '174:': [2381], '283-308Crossref': [2382], '(618)': [2385], 'Scholar);': [2387], 'anti-GFAP': [2389, 3015], 'antibody,': [2390, 2406, 2411], 'raised': [2391], 'rabbits,': [2393], 'DAKO': [2396], '(Glostrup,': [2397], 'Denmark);': [2398], 'anti-microtubule-associated': [2400], '2a': [2402], '+': [2403, 4155], '2b': [2404], '(MAP-2)': [2405], 'anti-β-actin': [2410, 3625], 'anti-rabbit': [2413], 'IgG': [2414], 'conjugated': [2415], 'tetramethylrhodamine': [2417], 'isothiocyanate': [2418], '(TRITC)': [2419], 'Sigma;': [2423], 'Ig': [2425], 'fluorescein': [2426], 'Jackson': [2429], 'ImmunoResearch': [2430], 'Laboratories': [2431], '(West': [2432], 'Grove,': [2433], 'PA);': [2434], 'IgM': [2437, 3143], 'Alexa': [2438, 3144], 'Fluor®': [2439, 3145], '488': [2440, 3146], 'Molecular': [2443], 'Probes': [2444], '(Eugene,': [2445], 'OR).': [2446], 'Chemicals—Poly-d-lysine,': [2447], 'p-phenylenediamine,': [2448], 'bis-benzimide,': [2449], 'dimethyl': [2451], 'sulfoxide': [2452], '(Me2SO),': [2453], 'reduced': [2456], 'oxidized': [2458], 'forms': [2459], 'Sigma.': [2466, 2539], 'DEA/NO': [2467, 2793, 2841, 2891, 3923, 4156, 4263, 4339, 4405, 4427, 4433], 'Alexis.': [2470], 'NADPH,': [2471], 'cytotoxicity': [2473, 3410, 4363], 'detection': [2474, 3411, 3640], 'kit': [2475, 2482, 2522, 3412, 3552, 3644], '(lactate': [2476], 'dehydrogenase,': [2477], 'LDH),': [2479], 'proliferation': [2481], '(3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl': [2484], 'tetrazolium': [2485], 'bromide,': [2486], 'MTT),': [2488], 'reductase': [2491, 3746], '(GR)': [2492], 'LY-83583': [2501], 'Biomol': [2504], '(Plymouth,': [2505], 'PA).': [2506], 'KT5823,': [2507], 'baicalein,': [2508, 4214], '(NDGA),': [2511], 'indomethacin,': [2512], 'clotrimazole': [2514, 4323], 'Calbiochem.': [2517], 'BCA': [2519, 3549], 'assay': [2521, 3216, 3458, 3551, 4352, 4441], 'Pierce.': [2525], 'All': [2526], 'reagents': [2528, 3208], 'highest': [2532], 'purity': [2533], 'commercially': [2534], 'available': [2535], 'Merck': [2537], 'Neuronal': [2540], 'Culture—Neuronal': [2541], 'enriched': [2542, 4060], 'embryonic': [2545], 'Sprague-Dawley': [2546], 'E-14': [2549], '(crown': [2550], 'rump,': [2551], 'length': [2552], '10–12': [2553], 'mm)': [2554], 'prepared': [2558], '(39Mena': [2562, 2673], 'Pardo': [2564, 2675], 'Paíno': [2566, 2582, 2677, 2693, 3351], 'C.L.': [2567, 2583, 2678, 2694, 3352], 'Yébenes': [2569, 2680], 'J.G.': [2570, 2681], '4:': [2573, 2684], '438-440Crossref': [2574, 2685], '(95)': [2577, 2688], '40Pardo': [2580, 2691], 'Protoc.': [2592, 2703, 3361], '127-132Crossref': [2595, 2706, 3364], '(34)': [2598, 2709, 3367], 'seeded': [2604], "Dulbecco's": [2606], '15%': [2611], 'density': [2617], '105': [2619, 3689], 'cells/cm2': [2620], 'multiwells': [2622], 'glass': [2624], 'cover': [2625, 3163, 3325, 3391], 'slides': [2626, 3326], 'coated': [2628], 'poly-d-lysine,': [2630], '4.5': [2631], 'μg/cm2,': [2632], '0.1': [2634, 3067, 3720, 3900], 'm': [2635, 3068, 3721], 'borate': [2636], 'buffer,': [2637, 3566], 'pH': [2638, 3072, 3525, 3590, 3727, 3799], '8.4.': [2639], 'kept': [2643], 'humidified': [2646], 'chamber': [2647], '37': [2649, 3284], '°C': [2650, 3083], '5%': [2653, 3601], 'CO2': [2654], 'atmosphere.': [2655], 'Twenty-four': [2656], 'hours': [2657], 'plating,': [2659], 'changed': [2663], 'serum-free': [2666], 'defined': [2667, 3202], '(EF12)': [2669], 'elsewhere': [2672], 'EF12': [2712], 'consisted': [2713], '1:1': [2716], '(v/v)': [2717, 3597], 'mixture': [2724], 'F-12': [2727], 'd-glucose': [2730], '(6': [2731], 'mg/ml),': [2732], 'insulin': [2733], '(25': [2734], 'μg/ml),': [2735, 2738], '(100': [2737], 'putrescine': [2739], '(60': [2740], 'μm),': [2741, 4315, 4319, 4322, 4325, 4328], 'progesterone': [2742], '(20': [2743, 3587], 'nm),': [2744], '(30': [2748, 3558], 'nm).': [2749], 'Experimental': [2750], 'Treatments—In': [2751], 'experiments': [2753, 2850, 2883], 'designed': [2754], 'study': [2756], 'viability,': [2765], 'received': [2773, 2868, 2922], '20': [2774, 2893, 2923, 3243, 3493, 3883, 4299], 'μm': [2775, 2890, 2894, 2924, 2995, 3884, 4180, 4242, 4257, 4262, 4300], 'vehicle,': [2778, 4330], 'then,': [2780, 4303], '5th': [2783, 2866, 2957, 4306], 'day,': [2784, 2867, 4307], 'pre-established': [2785, 4308], 'groups': [2786, 4309], 'treated': [2788, 2858, 3205, 3878, 4297, 4311, 4337], '(50': [2794, 3934], '100': [2796, 2889, 3286, 3697, 4261], 'μm)': [2797, 3935, 4341, 4396, 4418], '24': [2801, 2880, 3085, 3279, 3880, 3917, 4343, 4430], 'h.': [2802, 2881, 3256, 4344], 'Enzyme': [2803], 'three': [2807], 'metabolism,': [2812], '(NDGA': [2817], 'COX': [2821], '(indomethacin),': [2823], '(clotrimazole': [2828], 'proadifen)': [2830], 'corresponding': [2833], 'solvents,': [2834], 'routinely': [2836], '30': [2838, 2986, 3535, 3705, 4127, 4332, 4402], 'min': [2839, 2987, 3128, 3536, 3706, 4128, 4333, 4403], 'treatment': [2842, 2930, 3230, 3911, 4157, 4406], 'later.': [2848], 'metabolites,': [2855], 'above': [2862, 4116], 'and,': [2863, 3277], 'solvent': [2876], 'course': [2886], 'effects': [2887], 'expression,': [2898], 'alone': [2899], 'combination,': [2902], 'depicted.': [2905], 'long': [2907], 'term': [2908], 'viability': [2916, 4136, 4221, 4230, 4348, 4436], 'studied.': [2919], 'above,': [2927], 'proceeded': [2931], '(the': [2937], '8th': [2938], 'day': [2939, 2958], 'vitro).': [2941], 'experimental': [2944, 3212], 'design,': [2945], 'enzyme': [2946, 4193], 'vehicles': [2949], 'vitro.': [2960], 'neurotoxicity': [2966], 'higher': [2969], 'normal': [2974], 'homeostasis': [2976], 'investigated': [2978], 'pretreating': [2980], 'NDGA': [2983, 4133, 4313], 'baicalein': [2985, 4227, 4316, 4393], '200': [2992, 3260, 4417], '400': [2994], 'DEA/NO.': [2996], 'Immunocytochemistry—DA': [2997], 'characterized': [3000, 3953], 'anti-TH': [3007], '(1:100),': [3009], 'astrocytes': [3010], 'rabbit': [3013, 3620], '(1:500),': [3017], 'oligodendrocytes': [3019], 'anti-O1': [3022, 3115], '(1:10)': [3023, 3120], '(41Sommer': [3024], 'Schachner': [3026], 'Dev.': [3028], '1981;': [3030], '83:': [3031], '311-327Crossref': [3032], '(963)': [3035], 'To': [3038, 4104], 'detect': [3039], 'anti-MAP-2': [3048], '(1:250)': [3050], 'used.': [3052], 'MAP-2': [3057], 'immunostaining,': [3058], 'fixed': [3061, 3136, 3328], '4%': [3063, 3138, 3330], 'paraformaldehyde,': [3064, 3331], 'washed': [3065, 3132, 3692], 'saline': [3070], '(PBS),': [3071], '7.4,': [3073, 3526], 'permeabilized': [3074], 'ethanol-acetic': [3076], '(19:1),': [3078], 'incubated': [3080, 3125, 3253, 3618], 'antibodies': [3089, 3102], 'diluted': [3090], 'PBS': [3092], 'containing': [3093, 3492], '10%': [3094, 3569], 'serum.': [3097], 'Fluorescein-': [3098], 'rhodamine-conjugated': [3100], 'employed': [3104, 3655], 'visualize': [3106], 'fluorescent': [3110], 'microscopy.': [3111], 'oligodendrocyte': [3113], 'detection,': [3114], 'living': [3122], '15': [3127], 'room': [3130, 3609, 3807], 'temperature,': [3131], 'paraformaldehyde': [3139], 'previous': [3140], 'development.': [3147], 'immunoreactive': [3151], 'counted': [3154, 3168, 3386], 'one-seventh': [3156], 'total': [3159, 3829, 4385], 'area': [3160], 'slides.': [3164], 'predefined': [3170], 'parallel': [3171], 'strips': [3172], 'using': [3173, 3408, 3641], 'counting': [3175], 'reticule': [3176], 'inserted': [3177], 'ocular.': [3180], 'Cell': [3181, 3375, 3872], 'Viability': [3182], 'Measurements—Mitochondrial': [3183], 'activity': [3184, 3400, 3960, 4367], 'measured': [3186, 3302, 3402, 3451, 3666, 3770, 3961, 4232, 4349, 4364, 4438], 'MTT': [3189, 3215, 3246, 3963, 4351, 4440], 'assay.': [3190], 'Cells': [3191, 3322], 'grown': [3193], '24-well': [3195], 'plates': [3197], '500': [3199], 'μl': [3200, 3233, 3244, 3261, 3287, 3698], 'various': [3207], 'according': [3209], 'design.': [3213], 'measures': [3217], 'ability': [3219], 'metabolize': [3223], 'MTT.': [3224], 'At': [3225, 3257], 'end': [3227], 'period,': [3231], '300': [3232], 'removed': [3238], 'each': [3240], 'well,': [3241], 'solution': [3247, 3264, 3343, 3629], '(5': [3248, 3518], 'mg/ml)': [3249], '1': [3255, 3501, 3504, 3507, 3511, 3606, 3687, 3810], 'time,': [3259], 'solubilization': [3263], '(10%': [3265], 'SDS': [3266, 3563], 'HCl,': [3268, 3496], '0.01': [3269], 'm)': [3270], 'then': [3272, 3528, 3573], 'wells,': [3276], 'incubation': [3282], '°C,': [3285, 3709], 'transferred': [3289], 'onto': [3290], '96-well': [3291], 'microtiter': [3292, 3306, 3758], 'plates,': [3293], 'absorption': [3296], 'value': [3297], '540': [3299], 'nm': [3300, 3762], 'automatic': [3305, 3757], 'reader': [3307, 3759], '(Spectra': [3308], 'Fluor,': [3309], 'Tecan).': [3310], 'Chromatin': [3311], 'condensation': [3312, 3981, 4151], 'assessed': [3314], 'DNA': [3316, 3983], 'staining': [3317], 'bisbenzimide': [3319], '(Hoechst': [3320], '33342).': [3321], 'growing': [3323], 'nuclei': [3334, 4375], 'stained': [3336, 4376], 'bis-benzimide': [3338, 4378], 'anti-fading': [3342], '(3': [3344], '×': [3345, 3532, 3688], '10–6m,': [3346], 'final': [3347], 'concentration)': [3348], '(40Pardo': [3349], '42Hilwig': [3370], 'Gropp': [3372], '1975;': [3377], '91:': [3378], '457-460Crossref': [3379], 'one-fourteenth': [3388], 'slide': [3392], 'area.': [3393], 'necrotic': [3395], 'determination,': [3398], 'LDH': [3399, 3441, 3969, 4147, 4366], '(43Decker': [3413], 'Lohmann-Matthes': [3415], 'Immunol.': [3418], 'Methods.': [3419], '1988;': [3420], '115:': [3421], '61-69Crossref': [3422], '(1094)': [3425], 'expressed': [3429, 4380], 'percentage': [3432, 4357, 4383], 'versus': [3433, 3905, 4358, 4384], 'detergent-extracted': [3434], 'controls': [3435, 4142], '(100%': [3436], 'cytotoxicity).': [3437], 'system,': [3440], 'release': [3442, 3970, 4148], 'correlates': [3447], 'trypan': [3454], 'blue': [3455], 'dye': [3456], 'exclusion': [3457], 'Western': [3480], 'Blot': [3481], 'Analysis—Primary': [3482], 'homogenized': [3486], 'sonicator': [3489], 'buffer': [3491], 'mm': [3494, 3498, 3502, 3505, 3508, 3512, 3588, 3593, 3725], 'Tris': [3495], 'acetyl': [3499], 'lysine,': [3500], 'dithiothreitol,': [3503], 'EDTA,': [3506, 3726], 'phenylmethylsulfonyl': [3509], 'fluoride,': [3510], 'benzamidine,': [3513], 'leupeptin,': [3514], 'aprotinin,': [3515], 'pepstatin': [3517], 'μg/ml': [3519], 'each),': [3520], '0.25%': [3522], 'Nonidet': [3523], 'P-40,': [3524], 'centrifuged': [3529], '12,000': [3531], 'g': [3533], '°C.': [3539, 3633], 'supernatant': [3541], 'determination': [3546], 'electrophoretical': [3555], 'separation.': [3556], 'Samples': [3557], 'μg)': [3559], 'sample': [3564], 'loading': [3565], 'electrophoresed': [3567], 'SDS-polyacrylamide': [3570], 'gels,': [3571], 'electroblotted': [3574], '0.45-μm': [3576], 'nitrocellulose': [3577], 'membranes.': [3578], 'immunolabeling,': [3580], 'blots': [3582, 3635], 'blocked': [3584], 'TTBS': [3586], 'Tris-HCl,': [3589], '7.6,': [3591], '137': [3592], 'NaCl': [3594], 'plus': [3595], '0.1%': [3596], 'Tween': [3598], '20,': [3599], 'dry': [3602], 'skimmed': [3603], 'milk)': [3604], 'temperature.': [3610], 'After': [3611, 4289, 4429], 'blocking': [3612, 3628], 'nonspecific': [3613], 'binding,': [3614], 'membranes': [3616], 'anti-12-LOX': [3621], '(1:2000)': [3622], '(1:10000)': [3626], 'overnight': [3630], 'developed': [3637], 'chemiluminiscence': [3639], 'commercial': [3643], '(Amersham': [3645], 'Biosciences)': [3646], 'quantified': [3648], 'computer-assisted': [3650], 'video': [3651], 'densitometry.': [3652], 'β-actin': [3653], 'control': [3658], 'charge.': [3660], 'Measurements—Total': [3662], 'method': [3669, 3776], 'Tietze': [3671], '1969': [3673], '(44Tietze': [3674], 'Anal.': [3676, 3783], '1969;': [3678], '27:': [3679], '502-522Crossref': [3680], '(5555)': [3683], 'Briefly,': [3686, 3793], 'lysed': [3695], '3%': [3700], 'perchloric': [3701, 3795], '(PCA)': [3703], 'centrifuged,': [3710], 'neutralized': [3715], 'volumes': [3718], 'NaH2PO4': [3722], '5': [3724], '7.5.': [3728], 'Fifty': [3729], 'microliters': [3730], 'mixed': [3736], 'DTNB': [3738], '(0.6': [3739], 'mm),': [3740, 3743], 'NADPH': [3741], '(0.2': [3742], '(1': [3747], 'unit),': [3748], 'reaction': [3751, 3814], 'monitored': [3753], 'P96': [3756], '412': [3761], '6': [3764], 'min.': [3765], 'Oxidized': [3766], '(GSSG)': [3768], 'Griffith': [3778], '1980': [3780], '(45Griffith': [3781], '1980;': [3785], '106:': [3786], '207-212Crossref': [3787], '(4059)': [3790], 'extraction': [3797], 'neutralization,': [3800], 'derivatized': [3803], '2-vinylpyridine': [3805], 'temperature': [3808], 'h,': [3811], 'carried': [3816], 'out': [3817], 'above.': [3820], 'subtracting': [3825], 'GSSG': [3826], 'levels.': [3831], 'Statistical': [3832], 'Analysis—The': [3833], 'results': [3834, 3936], 'statistically': [3836, 3861], 'evaluated': [3837], 'significance': [3839], 'one-way': [3841], 'variance': [3844], '(ANOVA)': [3845], 'followed': [3846], 'Newman-Keuls': [3849], 'multiple': [3850], 'comparison': [3851], 'test': [3852], 'post': [3855], 'hoc': [3856], 'evaluation.': [3857], 'Differences': [3858], 'significant': [3862], 'p': [3864], '<': [3865], '0.05.': [3866], 'Inhibitors': [3867], 'Lipoxygenase': [3869], 'Block': [3870], 'NO-triggered': [3871], 'Death': [3873], 'Cultures—Midbrain': [3876], '17.5': [3891], '±': [3892, 3899], '0.4': [3893], 'μg/mg': [3894, 3901], '3.7': [3898], '(≈20%': [3904], 'control).': [3906], 'extensive': [3938], '(Fig.': [3944, 4040, 4267], '1,': [3945, 3986], 'b).': [3948], '75–85%': [3956], 'loss': [3957], 'assay,': [3964], '30–35%': [3966], 'increase': [3967], '70–80%': [3976], 'chromatin': [3980, 4150], 'fragmentation': [3984], '(Figs.': [3985, 4158, 4243], 'b,': [3989, 4361], '2;': [3991], 'shown),': [3995], 'rate': [4022], 'did': [4029], '48': [4038], '2,': [4041, 4161, 4246, 4268], 'b)': [4044], '72': [4047], '(data': [4049, 4181, 4276], 'shown)': [4051], 'accordance': [4053], '46Mytilineou': [4084], 'C.': [4085], 'Kokotos-Leonardi': [4086], 'E.T.': [4087], 'Kramer': [4088], 'B.C.': [4089], 'Jamindar': [4090], '1999;': [4096], '73:': 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