Title: The importance of the conformation of the tetrahedral intermediate for the α‐chymotrypsin‐catalyzed hydrolysis of peptide substrates
Abstract: FEBS LettersVolume 59, Issue 1 p. 105-108 Full-length articleFree Access The importance of the conformation of the tetrahedral intermediate for the α-chymotrypsin-catalyzed hydrolysis of peptide substrates Spartaco A. Bizzozero, Spartaco A. Bizzozero Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule, Universitätsstr. 6, CH-8006 Zürich, SwitzerlandSearch for more papers by this authorBernhard O. Zweifel, Bernhard O. Zweifel Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule, Universitätsstr. 6, CH-8006 Zürich, Switzerland Cornell University, Department of Chemistry, Ithaca, N.Y., USA. Search for more papers by this author Spartaco A. Bizzozero, Spartaco A. Bizzozero Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule, Universitätsstr. 6, CH-8006 Zürich, SwitzerlandSearch for more papers by this authorBernhard O. Zweifel, Bernhard O. Zweifel Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule, Universitätsstr. 6, CH-8006 Zürich, Switzerland Cornell University, Department of Chemistry, Ithaca, N.Y., USA. Search for more papers by this author First published: November 01, 1975 https://doi.org/10.1016/0014-5793(75)80351-6Citations: 39 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 G.L. Neil, C. Niemann, G.H. Hein, Nature, 210, (1966), 903– 907. 2 B. Belleau, G. Malek, J. Am. Chem. Soc., 90, (1968), 1651– 1652. 3 Y. Kiso, Y. Kai, H. Yajima, Chem. Pharm. Bull., 21, (1973), 2507– 2510. 4 W.K. Baumann, S.A. Bizzozero, H. Dutler, Eur. J. Biochem., 39, (1973), 381– 391. 5 B.O. Zweifel, Diss. Nr. 5529 (1975), ETH Zürich 6 S.A. Bizzozero, A.W. Kaiser, H. Dutler, Eur. J. Biochem., 33, (1973), 292– 300. 7 G.R. Schonbaum, B. Zerner, M.L. Bender, J. Biol. Chem., 236, (1961), 2930– 2935. 8 W.K. Baumann, S.A. Bizzozero, H. Dutler, FEBS Lett., 8, (1970), 257– 260. 9 J.J. Birktoft, D. Blow, J. Mol. Biol., 68, (1972), 187– 240. 10 T.A. Steitz, R. Henderson, D.M. Blow, J. Mol. Biol., 46, (1969), 337– 348. 11 A. Rühlmann, D. Kukla, P. Schwager, K. Bartels, R. Huber, J. Mol. Biol., 77, (1973), 417– 436. 12 R. Huber, D. Kukla, W. Bode, P. Schwager, K. Bartels, J. Deisenhofer, W. Steigemann, J. Mol. Biol., 89, (1974), 73– 101. 13 R.M. Sweet, H.T. Wright, J. Janin, C.H. Chothia, D.M. Blow, Biochemistry, 13, (1974), 4212– 4228. 14 M. Caplow, J. Am. Chem. Soc., 91, (1969), 3639– 3645. 15 M.H. O'Leary, M.D. Kluetz, J. Am. Chem. Soc., 92, (1970), 6089– 6090. 16 A.R. Fersht, Y. Requena, J. Am. Chem. Soc., 93, (1971), 7079– 7087. 17 H. Hirohara, M.L. Bender, R.S. Stark, Proc. Nat. Acad. Sci., 71, (1974), 1643– 1647. 18 P. Deslongchamps, P. Altani, D. Fréhel, A. Malaval, Can. J. Chem., 50, (1972), 3405– 3408. 19 P. Deslongchamps, C. Lebreux, R.J. Taillefer, Can. J. Chem., 51, (1973), 1665– 1669. 20 P. Deslongchamps, R. Chênevert, R.J. Taillefer, C. Moreau, J.K. Saunders, Can. J. Chem., 53, (1975), 1601– 1615. Citing Literature Volume59, Issue1November 01, 1975Pages 105-108 ReferencesRelatedInformation