Publication Information

{'id': 'https://openalex.org/W1987386449', 'doi': 'https://doi.org/10.1159/000217980', 'title': 'Membrane-Bound (MUC1) and Secretory (MUC2, MUC3, and MUC4) Mucin Gene Expression in Human Lung Cancer', 'display_name': 'Membrane-Bound (MUC1) and Secretory (MUC2, MUC3, and MUC4) Mucin Gene Expression in Human Lung Cancer', 'publication_year': 1996, 'publication_date': '1996-01-01', 'ids': {'openalex': 'https://openalex.org/W1987386449', 'doi': 'https://doi.org/10.1159/000217980', 'mag': '1987386449', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8638091'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000217980', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S12644804', 'display_name': 'Tumor Biology', 'issn_l': '1010-4283', 'issn': ['1010-4283', '1423-0380'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109102418', 'display_name': 'Phuong L. Nguyen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140408', 'display_name': 'Minneapolis VA Medical Center', 'ror': 'https://ror.org/032b8d361', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210117246', 'https://openalex.org/I4210117924', 'https://openalex.org/I4210140408']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Phuong L. Nguyen', 'raw_affiliation_strings': ['Department of Medicine, VA Medical Center, Minneapolis, MN 55417, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, VA Medical Center, Minneapolis, MN 55417, USA', 'institution_ids': ['https://openalex.org/I4210140408']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112828519', 'display_name': 'Gloria A. Niehans', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130238516', 'display_name': 'University of Minnesota', 'ror': 'https://ror.org/017zqws13', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130238516']}, {'id': 'https://openalex.org/I4210101327', 'display_name': 'Twin Cities Orthopedics', 'ror': 'https://ror.org/01en4s460', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210101327']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gloria A. Niehans', 'raw_affiliation_strings': ['University of Minnesota Twin Cities'], 'affiliations': [{'raw_affiliation_string': 'University of Minnesota Twin Cities', 'institution_ids': ['https://openalex.org/I130238516', 'https://openalex.org/I4210101327']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016904675', 'display_name': 'David L. Cherwitz', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210101327', 'display_name': 'Twin Cities Orthopedics', 'ror': 'https://ror.org/01en4s460', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210101327']}, {'id': 'https://openalex.org/I130238516', 'display_name': 'University of Minnesota', 'ror': 'https://ror.org/017zqws13', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130238516']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David L. Cherwitz', 'raw_affiliation_strings': ['University of Minnesota Twin Cities'], 'affiliations': [{'raw_affiliation_string': 'University of Minnesota Twin Cities', 'institution_ids': ['https://openalex.org/I4210101327', 'https://openalex.org/I130238516']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100363699', 'display_name': 'Young S. Kim', 'orcid': 'https://orcid.org/0000-0002-6766-1722'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Young S. Kim', 'raw_affiliation_strings': ['University of California at San Francisco,'], 'affiliations': [{'raw_affiliation_string': 'University of California at San Francisco,', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074446717', 'display_name': 'Samuel B. Ho', 'orcid': 'https://orcid.org/0000-0001-6730-6512'}, 'institutions': [{'id': 'https://openalex.org/I130238516', 'display_name': 'University of Minnesota', 'ror': 'https://ror.org/017zqws13', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130238516']}, {'id': 'https://openalex.org/I4210101327', 'display_name': 'Twin Cities Orthopedics', 'ror': 'https://ror.org/01en4s460', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210101327']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Samuel B. Ho', 'raw_affiliation_strings': ['University of Minnesota Twin Cities'], 'affiliations': [{'raw_affiliation_string': 'University of Minnesota Twin Cities', 'institution_ids': ['https://openalex.org/I130238516', 'https://openalex.org/I4210101327']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2000, 'currency': 'USD', 'value_usd': 2000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.673, 'has_fulltext': False, 'cited_by_count': 70, 'citation_normalized_percentile': {'value': 0.864274, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '17', 'issue': '3', 'first_page': '176', 'last_page': '192'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12334', 'display_name': 'Lung Cancer Research Studies', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10835', 'display_name': 'Carbohydrate Chemistry and Synthesis', 'score': 0.9894, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/muc1', 'display_name': 'MUC1', 'score': 0.940948}, {'id': 'https://openalex.org/keywords/mucin-2', 'display_name': 'Mucin 2', 'score': 0.52651703}], 'concepts': [{'id': 'https://openalex.org/C179264091', 'wikidata': 'https://www.wikidata.org/wiki/Q410862', 'display_name': 'Mucin', 'level': 2, 'score': 0.9704733}, {'id': 'https://openalex.org/C2777421810', 'wikidata': 'https://www.wikidata.org/wiki/Q21145188', 'display_name': 'MUC1', 'level': 3, 'score': 0.940948}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.62444943}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.55423886}, {'id': 'https://openalex.org/C2777116383', 'wikidata': 'https://www.wikidata.org/wiki/Q18029657', 'display_name': 'Mucin 2', 'level': 4, 'score': 0.52651703}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.52577734}, {'id': 'https://openalex.org/C108625454', 'wikidata': 'https://www.wikidata.org/wiki/Q187126', 'display_name': 'Glycoprotein', 'level': 2, 'score': 0.5084952}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.4402354}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.38510635}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.37130892}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.30324596}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.19813159}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.13615689}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.118124634}], 'mesh': [{'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009077', 'descriptor_name': 'Mucins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000230', 'descriptor_name': 'Adenocarcinoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003110', 'descriptor_name': 'Colonic Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003110', 'descriptor_name': 'Colonic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016384', 'descriptor_name': 'Consensus Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007124', 'descriptor_name': 'Immunoenzyme Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009077', 'descriptor_name': 'Mucins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009077', 'descriptor_name': 'Mucins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012334', 'descriptor_name': 'RNA, Neoplasm', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012334', 'descriptor_name': 'RNA, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000217980', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S12644804', 'display_name': 'Tumor Biology', 'issn_l': '1010-4283', 'issn': ['1010-4283', '1423-0380'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8638091', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.69}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W6177984', 'https://openalex.org/W2893844134', 'https://openalex.org/W2598798220', 'https://openalex.org/W2332227955', 'https://openalex.org/W2094438822', 'https://openalex.org/W2079963251', 'https://openalex.org/W2045400462', 'https://openalex.org/W2033709751', 'https://openalex.org/W1995938018', 'https://openalex.org/W1977877952'], 'abstract_inverted_index': {'Abnormalities': [0], 'of': [1, 31, 66, 73, 83, 117, 126, 145, 152, 160, 163], 'mucin-type': [2], 'glycoproteins': [3], 'have': [4], 'been': [5], 'described': [6], 'in': [7, 51, 56, 139, 149, 165], 'lung': [8, 57, 60, 93, 140, 154, 166], 'cancers,': [9, 97], 'but': [10], 'their': [11], 'molecular': [12], 'basis': [13], 'is': [14, 133], 'unknown.': [15], 'In': [16, 91], 'this': [17, 161], 'study,': [18], 'mucin-core-peptide-specific': [19], 'antibodies': [20], 'and': [21, 44, 46, 55, 75, 78, 85, 89, 102, 109, 129, 136], 'cDNA': [22], 'probes': [23], 'were': [24, 112], 'used': [25], 'to': [26, 35, 80], 'determine': [27], 'the': [28, 124, 157], 'relative': [29], 'expression': [30, 125], 'mucin': [32, 38, 49, 67, 87, 119, 164], 'genes': [33], 'corresponding': [34], 'one': [36, 47, 127], 'membrane-bound': [37, 128], '(MUC1),': [39], 'two': [40], 'intestinal': [41], 'mucins': [42, 132], '(MUC2': [43], 'MUC3),': [45], 'tracheobronchial': [48], '(MUC4)': [50], 'normal': [52], '(nonneoplastic)': [53], 'lung,': [54], 'neoplasms.': [58, 141], 'Normal': [59], 'tissues': [61], 'exhibited': [62, 98], 'a': [63, 150], 'distinct': [64], 'pattern': [65], 'gene': [68], 'expression,': [69], 'with': [70], 'high': [71], 'levels': [72, 82, 116], 'MUC1': [74], 'MUC4': [76, 103, 118, 147], 'mRNA': [77, 104], 'low': [79], 'absent': [81], 'MUC2': [84], 'MUC3': [86], 'immunoreactivity': [88], 'mRNA.': [90], 'contrast,': [92], 'adenocarcinomas,': [94], 'especially': [95], 'well-differentiated': [96], 'increased': [99, 115, 146], 'MUC1,': [100], 'MUC3,': [101], 'levels.': [105], 'Lung': [106], 'squamous-cell,': [107], 'adenosquamous,': [108], 'large-cell': [110], 'carcinomas': [111], 'characterized': [113], 'by': [114], 'only.': [120], 'We': [121], 'conclude': [122], 'that': [123], 'several': [130], 'secretory-type': [131], 'independently': [134], 'regulated': [135], 'markedly': [137], 'altered': [138], 'The': [142], 'frequent': [143], 'occurrence': [144], 'transcripts': [148], 'variety': [151], 'non-small-cell': [153], 'cancers': [155], 'indicates': [156], 'potential': [158], 'importance': [159], 'type': [162], 'cancer': [167], 'biology.': [168]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1987386449', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-29T05:46:15.635622', 'created_date': '2016-06-24'}