Publication Information

{'id': 'https://openalex.org/W1987282763', 'doi': 'https://doi.org/10.1371/journal.pgen.1005102', 'title': 'Zinc Finger Independent Genome-Wide Binding of Sp2 Potentiates Recruitment of Histone-Fold Protein Nf-y Distinguishing It from Sp1 and Sp3', 'display_name': 'Zinc Finger Independent Genome-Wide Binding of Sp2 Potentiates Recruitment of Histone-Fold Protein Nf-y Distinguishing It from Sp1 and Sp3', 'publication_year': 2015, 'publication_date': '2015-03-20', 'ids': {'openalex': 'https://openalex.org/W1987282763', 'doi': 'https://doi.org/10.1371/journal.pgen.1005102', 'mag': '1987282763', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25793500', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4368557'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pgen.1005102', 'pdf_url': 'https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005102&type=printable', 'source': {'id': 'https://openalex.org/S103870658', 'display_name': 'PLoS Genetics', 'issn_l': '1553-7390', 'issn': ['1553-7390', '1553-7404'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005102&type=printable', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5075576653', 'display_name': 'Sara Völkel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Sara Völkel', 'raw_affiliation_strings': ['Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003932561', 'display_name': 'Bastian Stielow', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Bastian Stielow', 'raw_affiliation_strings': ['Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013845611', 'display_name': 'Florian Finkernagel', 'orcid': 'https://orcid.org/0000-0002-1141-7499'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Florian Finkernagel', 'raw_affiliation_strings': ['Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061847107', 'display_name': 'Thorsten Stiewe', 'orcid': 'https://orcid.org/0000-0003-0134-7826'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Thorsten Stiewe', 'raw_affiliation_strings': ['Genomics Core Facility, Zentrum für Tumor- und Immunbiologie (ZTI), Philipps-University of Marburg, Marburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Genomics Core Facility, Zentrum für Tumor- und Immunbiologie (ZTI), Philipps-University of Marburg, Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050915821', 'display_name': 'Andrea Nist', 'orcid': 'https://orcid.org/0000-0002-7524-6801'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Andrea Nist', 'raw_affiliation_strings': ['Genomics Core Facility, Zentrum für Tumor- und Immunbiologie (ZTI), Philipps-University of Marburg, Marburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Genomics Core Facility, Zentrum für Tumor- und Immunbiologie (ZTI), Philipps-University of Marburg, Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5012841970', 'display_name': 'Guntram Suske', 'orcid': 'https://orcid.org/0000-0002-4807-0513'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Guntram Suske', 'raw_affiliation_strings': ['Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biology and Tumor Research (IMT), Philipps-University of Marburg, Marburg, Germany.', 'institution_ids': ['https://openalex.org/I161103922']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2655, 'currency': 'USD', 'value_usd': 2655, 'provenance': 'doaj'}, 'apc_paid': {'value': 2655, 'currency': 'USD', 'value_usd': 2655, 'provenance': 'doaj'}, 'fwci': 2.023, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 65, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '11', 'issue': '3', 'first_page': 'e1005102', 'last_page': 'e1005102'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/caat-box', 'display_name': 'CAAT box', 'score': 0.59785366}, {'id': 'https://openalex.org/keywords/chromatin-immunoprecipitation', 'display_name': 'Chromatin immunoprecipitation', 'score': 0.59044504}, {'id': 'https://openalex.org/keywords/sequence-motif', 'display_name': 'Sequence motif', 'score': 0.50757277}, {'id': 'https://openalex.org/keywords/sp1-transcription-factor', 'display_name': 'Sp1 transcription factor', 'score': 0.4403581}, {'id': 'https://openalex.org/keywords/dna-binding-site', 'display_name': 'DNA binding site', 'score': 0.42458022}], 'concepts': [{'id': 'https://openalex.org/C24284526', 'wikidata': 'https://www.wikidata.org/wiki/Q204785', 'display_name': 'Zinc finger', 'level': 4, 'score': 0.79927087}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7591902}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.6871125}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.6328418}, {'id': 'https://openalex.org/C107824862', 'wikidata': 'https://www.wikidata.org/wiki/Q616005', 'display_name': 'Binding site', 'level': 2, 'score': 0.6127352}, {'id': 'https://openalex.org/C179716448', 'wikidata': 'https://www.wikidata.org/wiki/Q2508056', 'display_name': 'CAAT box', 'level': 5, 'score': 0.59785366}, {'id': 'https://openalex.org/C134320426', 'wikidata': 'https://www.wikidata.org/wiki/Q901026', 'display_name': 'Chromatin immunoprecipitation', 'level': 5, 'score': 0.59044504}, {'id': 'https://openalex.org/C83640560', 'wikidata': 'https://www.wikidata.org/wiki/Q180951', 'display_name': 'Chromatin', 'level': 3, 'score': 0.5396952}, {'id': 'https://openalex.org/C117745874', 'wikidata': 'https://www.wikidata.org/wiki/Q901612', 'display_name': 'Sequence motif', 'level': 3, 'score': 0.50757277}, {'id': 'https://openalex.org/C64927066', 'wikidata': 'https://www.wikidata.org/wiki/Q36293', 'display_name': 'Histone', 'level': 3, 'score': 0.46482494}, {'id': 'https://openalex.org/C94966510', 'wikidata': 'https://www.wikidata.org/wiki/Q2252764', 'display_name': 'DNA-binding protein', 'level': 4, 'score': 0.45452726}, {'id': 'https://openalex.org/C57467964', 'wikidata': 'https://www.wikidata.org/wiki/Q14888082', 'display_name': 'Sp1 transcription factor', 'level': 5, 'score': 0.4403581}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.43432635}, {'id': 'https://openalex.org/C3662595', 'wikidata': 'https://www.wikidata.org/wiki/Q5205743', 'display_name': 'DNA binding site', 'level': 5, 'score': 0.42458022}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.41315478}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.27161497}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.2276544}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.22032866}], 'mesh': [{'descriptor_ui': 'D060066', 'descriptor_name': 'Protein Interaction Maps', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016329', 'descriptor_name': 'Sp1 Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D051704', 'descriptor_name': 'Sp2 Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D051705', 'descriptor_name': 'Sp3 Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016335', 'descriptor_name': 'Zinc Fingers', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023081', 'descriptor_name': 'CCAAT-Binding Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D023081', 'descriptor_name': 'CCAAT-Binding Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D023081', 'descriptor_name': 'CCAAT-Binding Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016678', 'descriptor_name': 'Genome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006657', 'descriptor_name': 'Histones', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006657', 'descriptor_name': 'Histones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059372', 'descriptor_name': 'Nucleotide Motifs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D059372', 'descriptor_name': 'Nucleotide Motifs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060066', 'descriptor_name': 'Protein Interaction Maps', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012045', 'descriptor_name': 'Regulatory Sequences, Nucleic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012045', 'descriptor_name': 'Regulatory Sequences, Nucleic Acid', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016329', 'descriptor_name': 'Sp1 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016329', 'descriptor_name': 'Sp1 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051704', 'descriptor_name': 'Sp2 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051704', 'descriptor_name': 'Sp2 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051705', 'descriptor_name': 'Sp3 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051705', 'descriptor_name': 'Sp3 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016335', 'descriptor_name': 'Zinc Fingers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pgen.1005102', 'pdf_url': 'https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005102&type=printable', 'source': {'id': 'https://openalex.org/S103870658', 'display_name': 'PLoS Genetics', 'issn_l': '1553-7390', 'issn': ['1553-7390', '1553-7404'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/9b3bc3d3b37f4917944cc17711979289', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4368557', 'pdf_url': 'https://europepmc.org/articles/pmc4368557?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368557', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://figshare.com/articles/dataset/_Zinc_Finger_Independent_Genome_Wide_Binding_of_Sp2_Potentiates_Recruitment_of_Histone_Fold_Protein_Nf_y_Distinguishing_It_from_Sp1_and_Sp3_/1345740', 'pdf_url': 'https://figshare.com/ndownloader/files/1964613', 'source': {'id': 'https://openalex.org/S4306400572', 'display_name': 'OPAL (Open@LaTrobe) (La Trobe University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I196829312', 'host_organization_name': 'La Trobe University', 'host_organization_lineage': ['https://openalex.org/I196829312'], 'host_organization_lineage_names': ['La Trobe University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25793500', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pgen.1005102', 'pdf_url': 'https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005102&type=printable', 'source': {'id': 'https://openalex.org/S103870658', 'display_name': 'PLoS Genetics', 'issn_l': '1553-7390', 'issn': ['1553-7390', '1553-7404'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1228798347', 'https://openalex.org/W1964963969', 'https://openalex.org/W1968345969', 'https://openalex.org/W1970943520', 'https://openalex.org/W1972835248', 'https://openalex.org/W1979342595', 'https://openalex.org/W1979786837', 'https://openalex.org/W1980722886', 'https://openalex.org/W1992788889', 'https://openalex.org/W1999319214', 'https://openalex.org/W2003911872', 'https://openalex.org/W2004181770', 'https://openalex.org/W2008086014', 'https://openalex.org/W2016923780', 'https://openalex.org/W2021929759', 'https://openalex.org/W2023115583', 'https://openalex.org/W2029009254', 'https://openalex.org/W2046801755', 'https://openalex.org/W2050259276', 'https://openalex.org/W2051875167', 'https://openalex.org/W2057504005', 'https://openalex.org/W2065455422', 'https://openalex.org/W2083553538', 'https://openalex.org/W2087504707', 'https://openalex.org/W2093586924', 'https://openalex.org/W2100592151', 'https://openalex.org/W2105640296', 'https://openalex.org/W2106169455', 'https://openalex.org/W2110905563', 'https://openalex.org/W2117871175', 'https://openalex.org/W2118608526', 'https://openalex.org/W2120422553', 'https://openalex.org/W2121077484', 'https://openalex.org/W2124080033', 'https://openalex.org/W2132621491', 'https://openalex.org/W2133778193', 'https://openalex.org/W2136204556', 'https://openalex.org/W2139146701', 'https://openalex.org/W2142613777', 'https://openalex.org/W2143067946', 'https://openalex.org/W2144109825', 'https://openalex.org/W2148153414', 'https://openalex.org/W2148896458', 'https://openalex.org/W2151951496', 'https://openalex.org/W2155304372', 'https://openalex.org/W2157952888', 'https://openalex.org/W2171808845', 'https://openalex.org/W4210290733', 'https://openalex.org/W4248573544'], 'related_works': ['https://openalex.org/W4206488633', 'https://openalex.org/W2435377735', 'https://openalex.org/W2412905053', 'https://openalex.org/W2412518974', 'https://openalex.org/W2089517914', 'https://openalex.org/W2075656726', 'https://openalex.org/W2027881262', 'https://openalex.org/W2023687962', 'https://openalex.org/W1975240682', 'https://openalex.org/W1868379549'], 'abstract_inverted_index': {'Transcription': [0], 'factors': [1], 'are': [2, 23, 55, 174], 'grouped': [3], 'into': [4], 'families': [5], 'based': [6], 'on': [7], 'sequence': [8], 'similarity': [9], 'within': [10], 'functional': [11], 'domains,': [12], 'particularly': [13], 'DNA-binding': [14], 'domains.': [15], 'The': [16, 128], 'Specificity': [17], 'proteins': [18, 54], 'Sp1,': [19, 105], 'Sp2': [20, 106, 133, 136, 145, 191, 223, 229], 'and': [21, 35, 107, 116, 123, 146], 'Sp3': [22, 108, 117, 147], 'paradigmatic': [24], 'of': [25, 69, 104, 132, 144, 157, 171, 179, 190, 222, 232, 240, 253, 262], 'closely': [26], 'related': [27], 'transcription': [28, 207, 255], 'factors.': [29], 'They': [30], 'share': [31], 'amino-terminal': [32, 184], 'glutamine-rich': [33, 183], 'regions': [34], 'a': [36], 'conserved': [37], 'carboxy-terminal': [38], 'zinc': [39, 166], 'finger': [40], 'domain': [41], 'that': [42], 'can': [43], 'bind': [44, 80], 'to': [45, 81, 125, 192, 224, 234, 267], 'GC': [46, 126], 'rich': [47], 'motifs': [48], 'in': [49, 64, 109, 149, 196, 264, 269], 'vitro.': [50], 'All': [51], 'three': [52], 'Sp': [53], 'ubiquitously': [56], 'expressed;': [57], 'yet': [58], 'they': [59, 79, 173], 'carry': [60], 'out': [61], 'unique': [62], 'functions': [63], 'vivo': [65], 'raising': [66], 'the': [67, 100, 120, 165, 182, 201, 211, 238], 'question': [68], 'how': [70, 88], 'specificity': [71], 'is': [72, 76, 92, 134, 186, 218], 'achieved.': [73], 'Crucially,': [74], 'it': [75], 'unknown': [77], 'whether': [78], 'distinct': [82], 'genomic': [83, 101, 129, 158, 169], 'sites': [84, 236], 'and,': [85], 'if': [86], 'so,': [87], 'binding': [89, 102, 130, 159, 170, 178, 206, 231, 266], 'site': [90, 160], 'selection': [91], 'accomplished.': [93], 'In': [94], 'this': [95], 'study,': [96], 'we': [97], 'have': [98, 199], 'examined': [99], 'patterns': [103], 'mouse': [110], 'embryonic': [111], 'fibroblasts': [112], 'by': [113], 'ChIP-seq.': [114], 'Sp1': [115], 'essentially': [118], 'occupy': [119], 'same': [121], 'promoters': [122, 195], 'localize': [124], 'boxes.': [127], 'pattern': [131], 'different;': [135], 'primarily': [137], 'localizes': [138], 'at': [139], 'CCAAT': [140, 204], 'motifs.': [141], 'Consistently,': [142], 're-expression': [143], 'mutants': [148], 'corresponding': [150], 'knockout': [151], 'MEFs': [152], 'revealed': [153], 'strikingly': [154, 249], 'different': [155, 250], 'modes': [156], 'selection.': [161], 'Most': [162], 'significantly,': [163], 'while': [164], 'fingers': [167], 'dictate': [168], 'Sp3,': [172], 'completely': [175], 'dispensable': [176], 'for': [177, 188, 214, 220], 'Sp2.': [180], 'Instead,': [181], 'region': [185], 'sufficient': [187], 'recruitment': [189, 221, 251], 'its': [193], 'target': [194], 'vivo.': [197, 270], 'We': [198], 'identified': [200], 'trimeric': [202], 'histone-fold': [203], 'box': [205], 'factor': [208, 256], 'Nf-y': [209, 217, 233], 'as': [210], 'major': [212], 'partner': [213], 'Sp2-chromatin': [215], 'interaction.': [216], 'critical': [219], 'co-occupied': [225], 'regulatory': [226], 'elements.': [227], 'Equally,': [228], 'potentiates': [230], 'shared': [235], 'indicating': [237], 'existence': [239], 'an': [241, 259], 'extensive': [242], 'Sp2-Nf-y': [243], 'interaction': [244], 'network.': [245], 'Our': [246], 'results': [247], 'unveil': [248], 'mechanisms': [252], 'Sp1/Sp2/Sp3': [254], 'members': [257], 'uncovering': [258], 'unexpected': [260], 'layer': [261], 'complexity': [263], 'their': [265], 'chromatin': [268]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1987282763', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 4}], 'updated_date': '2025-01-08T03:49:57.465986', 'created_date': '2016-06-24'}