Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1986524637', 'doi': 'https://doi.org/10.1016/j.toxicon.2009.11.006', 'title': 'Isolation and characterization of a new serine protease with thrombin-like activity (TLBm) from the venom of the snake Bothrops marajoensis', 'display_name': 'Isolation and characterization of a new serine protease with thrombin-like activity (TLBm) from the venom of the snake Bothrops marajoensis', 'publication_year': 2009, 'publication_date': '2009-11-19', 'ids': {'openalex': 'https://openalex.org/W1986524637', 'doi': 'https://doi.org/10.1016/j.toxicon.2009.11.006', 'mag': '1986524637', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19931298'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.toxicon.2009.11.006', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42803210', 'display_name': 'Toxicon', 'issn_l': '0041-0101', 'issn': ['0041-0101', '1879-3150'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5074933139', 'display_name': 'Augusto Vilca-Quispe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Augusto Vilca-Quispe', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055508651', 'display_name': 'Luis Alberto Ponce-Soto', 'orcid': 'https://orcid.org/0000-0001-5976-2913'}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': True, 'raw_author_name': 'Luis Alberto Ponce-Soto', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil', 'Department of Pharmacology, Faculty of Medical Science (FCM), State University of Campinas (UNICAMP), Campinas, SP, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}, {'raw_affiliation_string': 'Department of Pharmacology, Faculty of Medical Science (FCM), State University of Campinas (UNICAMP), Campinas, SP, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037369019', 'display_name': 'Flávia Vischi Winck', 'orcid': 'https://orcid.org/0000-0002-8399-4156'}, 'institutions': [{'id': 'https://openalex.org/I4210105972', 'display_name': 'Max Planck Institute of Molecular Plant Physiology', 'ror': 'https://ror.org/01fbde567', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210105972']}, {'id': 'https://openalex.org/I176453806', 'display_name': 'University of Potsdam', 'ror': 'https://ror.org/03bnmw459', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I176453806']}, {'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR', 'DE'], 'is_corresponding': False, 'raw_author_name': 'Flavia Vischi Winck', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil', 'Max Planck Institute of Molecular Plant Physiology and University of Potsdam, Potsdam, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max Planck Institute of Molecular Plant Physiology and University of Potsdam, Potsdam, Germany', 'institution_ids': ['https://openalex.org/I4210105972', 'https://openalex.org/I176453806']}, {'raw_affiliation_string': 'Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111692599', 'display_name': 'Sérgio Marangoni', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181391015', 'display_name': 'Universidade Estadual de Campinas (UNICAMP)', 'ror': 'https://ror.org/04wffgt70', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I181391015']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Sergio Marangoni', 'raw_affiliation_strings': ['Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Institute of Biology (IB), Campinas, SP, Brazil', 'institution_ids': ['https://openalex.org/I181391015']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5055508651'], 'corresponding_institution_ids': ['https://openalex.org/I181391015'], 'apc_list': {'value': 3090, 'currency': 'USD', 'value_usd': 3090, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.484, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 48, 'citation_normalized_percentile': {'value': 0.908789, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '55', 'issue': '4', 'first_page': '745', 'last_page': '753'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11353', 'display_name': 'Venomous Animal Envenomation and Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11353', 'display_name': 'Venomous Animal Envenomation and Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13326', 'display_name': 'Biochemical and Structural Characterization', 'score': 0.9062, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bothrops', 'display_name': 'Bothrops', 'score': 0.6213437}, {'id': 'https://openalex.org/keywords/isolation', 'display_name': 'Isolation', 'score': 0.59564346}], 'concepts': [{'id': 'https://openalex.org/C2779448229', 'wikidata': 'https://www.wikidata.org/wiki/Q3386847', 'display_name': 'Venom', 'level': 2, 'score': 0.742363}, {'id': 'https://openalex.org/C2777807008', 'wikidata': 'https://www.wikidata.org/wiki/Q87324999', 'display_name': 'Serine protease', 'level': 4, 'score': 0.668023}, {'id': 'https://openalex.org/C2779815518', 'wikidata': 'https://www.wikidata.org/wiki/Q468875', 'display_name': 'Bothrops', 'level': 4, 'score': 0.6213437}, {'id': 'https://openalex.org/C2776725428', 'wikidata': 'https://www.wikidata.org/wiki/Q424200', 'display_name': 'Snake venom', 'level': 3, 'score': 0.61026365}, {'id': 'https://openalex.org/C2775941552', 'wikidata': 'https://www.wikidata.org/wiki/Q25212305', 'display_name': 'Isolation (microbiology)', 'level': 2, 'score': 0.59564346}, {'id': 'https://openalex.org/C2776414213', 'wikidata': 'https://www.wikidata.org/wiki/Q183290', 'display_name': 'Serine', 'level': 3, 'score': 0.4860728}, {'id': 'https://openalex.org/C2777292125', 'wikidata': 'https://www.wikidata.org/wiki/Q409166', 'display_name': 'Thrombin', 'level': 3, 'score': 0.455679}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.45066085}, {'id': 'https://openalex.org/C2776714187', 'wikidata': 'https://www.wikidata.org/wiki/Q212410', 'display_name': 'Protease', 'level': 3, 'score': 0.44048783}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39126897}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.34705567}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.19860506}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.15909502}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.07329041}, {'id': 'https://openalex.org/C89560881', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017837', 'descriptor_name': 'Bothrops', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003435', 'descriptor_name': 'Crotalid Venoms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020134', 'descriptor_name': 'Catalytic Domain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002851', 'descriptor_name': 'Chromatography, High Pressure Liquid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003435', 'descriptor_name': 'Crotalid Venoms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008970', 'descriptor_name': 'Molecular Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010974', 'descriptor_name': 'Platelet Aggregation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010974', 'descriptor_name': 'Platelet Aggregation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057057', 'descriptor_name': 'Serine Proteases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D019032', 'descriptor_name': 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.toxicon.2009.11.006', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42803210', 'display_name': 'Toxicon', 'issn_l': '0041-0101', 'issn': ['0041-0101', '1879-3150'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19931298', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.55, 'id': 'https://metadata.un.org/sdg/14', 'display_name': 'Life below water'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 46, 'referenced_works': ['https://openalex.org/W1529569975', 'https://openalex.org/W1591954937', 'https://openalex.org/W182036647', 'https://openalex.org/W1906324427', 'https://openalex.org/W1914719432', 'https://openalex.org/W1966497279', 'https://openalex.org/W1968525459', 'https://openalex.org/W1968875577', 'https://openalex.org/W1970462433', 'https://openalex.org/W1978092409', 'https://openalex.org/W1980712245', 'https://openalex.org/W1982797973', 'https://openalex.org/W1993547719', 'https://openalex.org/W2002612703', 'https://openalex.org/W2005616283', 'https://openalex.org/W2010146383', 'https://openalex.org/W2019630454', 'https://openalex.org/W2020537001', 'https://openalex.org/W2020921331', 'https://openalex.org/W2023450902', 'https://openalex.org/W2038432485', 'https://openalex.org/W2041216209', 'https://openalex.org/W2041976469', 'https://openalex.org/W2045766819', 'https://openalex.org/W2051984156', 'https://openalex.org/W2053115647', 'https://openalex.org/W2062920331', 'https://openalex.org/W2066459274', 'https://openalex.org/W2066518618', 'https://openalex.org/W2070462299', 'https://openalex.org/W2078328099', 'https://openalex.org/W2093066447', 'https://openalex.org/W2093487114', 'https://openalex.org/W2097806792', 'https://openalex.org/W2130412205', 'https://openalex.org/W2135385800', 'https://openalex.org/W2148187441', 'https://openalex.org/W2148505321', 'https://openalex.org/W2164926051', 'https://openalex.org/W2168535596', 'https://openalex.org/W2169022678', 'https://openalex.org/W2179897811', 'https://openalex.org/W2211424526', 'https://openalex.org/W2433065954', 'https://openalex.org/W2803587840', 'https://openalex.org/W644821230'], 'related_works': ['https://openalex.org/W3174692683', 'https://openalex.org/W3111792067', 'https://openalex.org/W2962764189', 'https://openalex.org/W2810350411', 'https://openalex.org/W2152378697', 'https://openalex.org/W2084738263', 'https://openalex.org/W2061260311', 'https://openalex.org/W2048229424', 'https://openalex.org/W1978726768', 'https://openalex.org/W1971474434'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1986524637', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-06T02:57:50.937686', 'created_date': '2016-06-24'}