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'tyrosine': [44], 'phosphatase,': [45], 'SHP-2.': [46], 'Comparing': [47], 'responses': [49], 'mouse': [51], 'embryonic': [52], 'fibroblasts': [53], '(MEFs),': [54], 'expressing': [55, 170], 'either': [56], 'WT': [57], 'or': [58], 'functionally': [59], 'inactive/truncated': [60], 'SHP-2,': [61], 'find': [63], 'that': [64, 100, 122, 136], 'inactivation': [65], 'SHP-2': [67, 77, 172, 208], 'remarkably': [68], 'sensitizes': [69], 'EGCG-mediated': [72], 'killing.': [73], 'MEFs': [74, 132], 'lacking': [75, 133], 'functional': [76], 'undergo': [78], 'massive': [79], 'upon': [81], 'treatment': [82, 149], 'with': [83], 'EGCG.': [84], 'By': [85], 'comparing': [86], 'gene': [87, 179, 202], 'expression': [88, 124, 138, 152, 225], 'profiles,': [89], 'identified': [92, 207, 217], 'set': [94], 'transcriptional': [96], 'targets': [97], 'p53': [99, 177, 200, 221, 231], 'are': [101], 'modulated': [103], 'undergoing': [106], 'apoptosis.': [107], 'Western': [108], 'blot': [109], 'and': [110, 156, 176, 199, 215], 'real-time': [111], 'PCR': [112], 'analyses': [113], 'select': [116], 'group': [117], 'genes': [119, 223], 'confirm': [121], 'is': [125, 144, 185, 226], 'SHP-2-dependent.': [126], 'Similar': [127], 'observations': [128], 'were': [129], 'made': [130], 'p53,': [134], 'confirming': [135], 'these': [140], '“p53': [141], 'target': [142, 178, 201, 222], 'genes”': [143], 'p53-independent.': [145], 'addition,': [147], 'EGCG': [148], 'induced': [150], 'p73': [154, 167], 'mRNA': [155], 'protein': [157], 'both': [159], 'types,': [161], 'but': [162, 232], 'not': [163, 228], 'p63.': [164], 'Inactivation': [165], 'nonfunctional': [171], 'markedly': [173], 'inhibited': [174], 'expression.': [180, 203], 'Although': [181], 'phosphorylation': [182], 'JNK': [184], 'regulated': [187], 'SHP2,': [189], 'it': [190], 'was': [191], 'found': [192], 'be': [194], 'dispensable': [195], 'for': [196], 'EGCG-induced': [197], 'Our': [204], 'results': [205], 'as': [209], 'negative': [211], 'regulator': 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