Nuclear Factor-κ B Repression in Antiinflammation and Immunosuppression by Glucocorticoids

Name: Work Video:
Duration: 3 min 30 s
Bart van der Burg; Johan Lidén; Sam Okret; Franck Delaunay; Sacha Wissink; Paul T. van der Saag; Jan-Ακε Gustafsson
{'id': 'https://openalex.org/W1986004201', 'doi': 'https://doi.org/10.1016/s1043-2760(97)00006-4', 'title': 'Nuclear Factor-κ B Repression in Antiinflammation and Immunosuppression by Glucocorticoids', 'display_name': 'Nuclear Factor-κ B Repression in Antiinflammation and Immunosuppression by Glucocorticoids', 'publication_year': 1997, 'publication_date': '1997-05-01', 'ids': {'openalex': 'https://openalex.org/W1986004201', 'doi': 'https://doi.org/10.1016/s1043-2760(97)00006-4', 'mag': '1986004201', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18406801'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s1043-2760(97)00006-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S93802863', 'display_name': 'Trends in Endocrinology and Metabolism', 'issn_l': '1043-2760', 'issn': ['1043-2760', '1879-3061'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102964306', 'display_name': 'Bart van der Burg', 'orcid': 'https://orcid.org/0000-0002-2561-9892'}, 'institutions': [{'id': 'https://openalex.org/I4210115206', 'display_name': 'Hubrecht Institute for Developmental Biology and Stem Cell Research', 'ror': 'https://ror.org/023qc4a07', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I1322597698', 'https://openalex.org/I4210115206']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Bart van der Burg', 'raw_affiliation_strings': ['Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT Utrecht, Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT Utrecht, Netherlands', 'institution_ids': ['https://openalex.org/I4210115206']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112038503', 'display_name': 'Johan Lidén', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Johan Liden', 'raw_affiliation_strings': ['Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.', 'institution_ids': ['https://openalex.org/I28166907']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021443948', 'display_name': 'Sam Okret', 'orcid': 'https://orcid.org/0000-0003-0822-1847'}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Sam Okret', 'raw_affiliation_strings': ['Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.', 'institution_ids': ['https://openalex.org/I28166907']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010951327', 'display_name': 'Franck Delaunay', 'orcid': 'https://orcid.org/0000-0003-4927-1701'}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Franck Delaunay', 'raw_affiliation_strings': ['Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.', 'institution_ids': ['https://openalex.org/I28166907']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113633661', 'display_name': 'Sacha Wissink', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210115206', 'display_name': 'Hubrecht Institute for Developmental Biology and Stem Cell Research', 'ror': 'https://ror.org/023qc4a07', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I1322597698', 'https://openalex.org/I4210115206']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Sacha Wissink', 'raw_affiliation_strings': ['Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT Utrecht, Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT Utrecht, Netherlands', 'institution_ids': ['https://openalex.org/I4210115206']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108367804', 'display_name': 'Paul T. van der Saag', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210115206', 'display_name': 'Hubrecht Institute for Developmental Biology and Stem Cell Research', 'ror': 'https://ror.org/023qc4a07', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I1322597698', 'https://openalex.org/I4210115206']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Paul T van der Saag', 'raw_affiliation_strings': ['Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT Utrecht, Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT Utrecht, Netherlands', 'institution_ids': ['https://openalex.org/I4210115206']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5085801141', 'display_name': 'Jan-Ακε Gustafsson', 'orcid': 'https://orcid.org/0000-0002-1472-1373'}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Jan-Åke Gustafsson', 'raw_affiliation_strings': ['Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Nutrition, Karolinska Institute, NOVUM, S-14186 Huddinge, Sweden.', 'institution_ids': ['https://openalex.org/I28166907']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6830, 'currency': 'USD', 'value_usd': 6830, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.896, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 56, 'citation_normalized_percentile': {'value': 0.899662, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '8', 'issue': '4', 'first_page': '152', 'last_page': '157'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11591', 'display_name': 'NF-κB Signaling Pathways', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11591', 'display_name': 'NF-κB Signaling Pathways', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transrepression', 'display_name': 'Transrepression', 'score': 0.95458025}, {'id': 'https://openalex.org/keywords/immunosuppression', 'display_name': 'Immunosuppression', 'score': 0.61560565}, {'id': 'https://openalex.org/keywords/transcriptional-activity', 'display_name': 'Transcriptional activity', 'score': 0.42548308}], 'concepts': [{'id': 'https://openalex.org/C59300778', 'wikidata': 'https://www.wikidata.org/wiki/Q7835354', 'display_name': 'Transrepression', 'level': 5, 'score': 0.95458025}, {'id': 'https://openalex.org/C1292079', 'wikidata': 'https://www.wikidata.org/wiki/Q3817769', 'display_name': 'Transactivation', 'level': 4, 'score': 0.8875438}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.80637944}, {'id': 'https://openalex.org/C59493245', 'wikidata': 'https://www.wikidata.org/wiki/Q14877410', 'display_name': 'Glucocorticoid receptor', 'level': 3, 'score': 0.75966877}, {'id': 'https://openalex.org/C2780252810', 'wikidata': 'https://www.wikidata.org/wiki/Q1455316', 'display_name': 'Immunosuppression', 'level': 2, 'score': 0.61560565}, {'id': 'https://openalex.org/C186310378', 'wikidata': 'https://www.wikidata.org/wiki/Q941796', 'display_name': 'Psychological repression', 'level': 4, 'score': 0.6014317}, {'id': 'https://openalex.org/C63932345', 'wikidata': 'https://www.wikidata.org/wiki/Q422500', 'display_name': 'Nuclear receptor', 'level': 4, 'score': 0.53398746}, {'id': 'https://openalex.org/C2780841215', 'wikidata': 'https://www.wikidata.org/wiki/Q422549', 'display_name': 'Glucocorticoid', 'level': 2, 'score': 0.4995017}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.48979974}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.4430005}, {'id': 'https://openalex.org/C2992339755', 'wikidata': 'https://www.wikidata.org/wiki/Q3817769', 'display_name': 'Transcriptional activity', 'level': 4, 'score': 0.42548308}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.390746}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.38382488}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33230194}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.16769892}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1070627}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.08461347}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s1043-2760(97)00006-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S93802863', 'display_name': 'Trends in Endocrinology and Metabolism', 'issn_l': '1043-2760', 'issn': ['1043-2760', '1879-3061'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18406801', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.83, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W128790911', 'https://openalex.org/W1487636984', 'https://openalex.org/W1514719946', 'https://openalex.org/W1522773084', 'https://openalex.org/W1551136566', 'https://openalex.org/W1591317354', 'https://openalex.org/W1592606160', 'https://openalex.org/W1606150020', 'https://openalex.org/W1612144722', 'https://openalex.org/W1717444875', 'https://openalex.org/W1854733189', 'https://openalex.org/W1868478050', 'https://openalex.org/W1874865406', 'https://openalex.org/W1968455941', 'https://openalex.org/W1970815880', 'https://openalex.org/W1978445938', 'https://openalex.org/W1987557547', 'https://openalex.org/W1990581082', 'https://openalex.org/W1995728045', 'https://openalex.org/W1999855196', 'https://openalex.org/W2001963326', 'https://openalex.org/W2002992087', 'https://openalex.org/W2004002827', 'https://openalex.org/W2004343006', 'https://openalex.org/W2009662708', 'https://openalex.org/W2019540125', 'https://openalex.org/W2030033188', 'https://openalex.org/W2034411805', 'https://openalex.org/W2045254737', 'https://openalex.org/W2049671131', 'https://openalex.org/W2050947729', 'https://openalex.org/W2056034929', 'https://openalex.org/W2058971952', 'https://openalex.org/W2075227075', 'https://openalex.org/W2095226322', 'https://openalex.org/W2097483036', 'https://openalex.org/W2100250344', 'https://openalex.org/W2110670037', 'https://openalex.org/W2115598483', 'https://openalex.org/W2119725374', 'https://openalex.org/W2142541950', 'https://openalex.org/W2151892297', 'https://openalex.org/W2158110584', 'https://openalex.org/W2159674010', 'https://openalex.org/W2402146733', 'https://openalex.org/W2868496', 'https://openalex.org/W4254644374', 'https://openalex.org/W4256430334', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W3895459', 'https://openalex.org/W3200284037', 'https://openalex.org/W2074257679', 'https://openalex.org/W2069505390', 'https://openalex.org/W2069452057', 'https://openalex.org/W2054115898', 'https://openalex.org/W2049224802', 'https://openalex.org/W2044045263', 'https://openalex.org/W2027499069', 'https://openalex.org/W1986237959'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1986004201', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-14T06:36:43.255465', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
