Publication Information

{'id': 'https://openalex.org/W1985924867', 'doi': 'https://doi.org/10.1096/fj.12-213801', 'title': 'Orai3 is an estrogen receptor α‐regulated Ca <sup>2+</sup> channel that promotes tumorigenesis', 'display_name': 'Orai3 is an estrogen receptor α‐regulated Ca <sup>2+</sup> channel that promotes tumorigenesis', 'publication_year': 2012, 'publication_date': '2012-09-19', 'ids': {'openalex': 'https://openalex.org/W1985924867', 'doi': 'https://doi.org/10.1096/fj.12-213801', 'mag': '1985924867', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22993197', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3528310'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1096/fj.12-213801', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S25293849', 'display_name': 'The FASEB Journal', 'issn_l': '0892-6638', 'issn': ['0892-6638', '1530-6860'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3528310', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091353622', 'display_name': 'Rajender K. Motiani', 'orcid': 'https://orcid.org/0000-0002-8971-9008'}, 'institutions': [{'id': 'https://openalex.org/I77920804', 'display_name': 'Albany Medical Center Hospital', 'ror': 'https://ror.org/0307crw42', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I77920804']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rajender K. Motiani', 'raw_affiliation_strings': ['Center for Cardiovascular Sciences, Albany Medical College, Albany, NY, 12208, USA.'], 'affiliations': [{'raw_affiliation_string': 'Center for Cardiovascular Sciences, Albany Medical College, Albany, NY, 12208, USA.', 'institution_ids': ['https://openalex.org/I77920804']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063808923', 'display_name': 'Xuexin Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I77920804', 'display_name': 'Albany Medical Center Hospital', 'ror': 'https://ror.org/0307crw42', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I77920804']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Xuexin Zhang', 'raw_affiliation_strings': ['Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA'], 'affiliations': [{'raw_affiliation_string': 'Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA', 'institution_ids': ['https://openalex.org/I77920804']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042605329', 'display_name': 'Kelly E. Harmon', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I77920804', 'display_name': 'Albany Medical Center Hospital', 'ror': 'https://ror.org/0307crw42', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I77920804']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kelly E. Harmon', 'raw_affiliation_strings': ['Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA'], 'affiliations': [{'raw_affiliation_string': 'Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA', 'institution_ids': ['https://openalex.org/I77920804']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108451161', 'display_name': 'Rebecca S. Keller', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I77920804', 'display_name': 'Albany Medical Center Hospital', 'ror': 'https://ror.org/0307crw42', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I77920804']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rebecca S. Keller', 'raw_affiliation_strings': ['Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA'], 'affiliations': [{'raw_affiliation_string': 'Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA', 'institution_ids': ['https://openalex.org/I77920804']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109213166', 'display_name': 'Khalid Matrougui', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210105813', 'display_name': 'Tula University', 'ror': 'https://ror.org/01kfqj356', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I4210105813']}, {'id': 'https://openalex.org/I114832834', 'display_name': 'Tulane University', 'ror': 'https://ror.org/04vmvtb21', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114832834']}], 'countries': ['RU', 'US'], 'is_corresponding': False, 'raw_author_name': 'Khalid Matrougui', 'raw_affiliation_strings': ['Department of Physiology, Hypertension and Renal Center of ExcellenceTulane UniversityNew OrleansLousianaUSA'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology, Hypertension and Renal Center of ExcellenceTulane UniversityNew OrleansLousianaUSA', 'institution_ids': ['https://openalex.org/I4210105813', 'https://openalex.org/I114832834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103075851', 'display_name': 'James A. Bennett', 'orcid': 'https://orcid.org/0000-0002-8466-5995'}, 'institutions': [{'id': 'https://openalex.org/I77920804', 'display_name': 'Albany Medical Center Hospital', 'ror': 'https://ror.org/0307crw42', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I77920804']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James A. Bennett', 'raw_affiliation_strings': ['Center for Immunology and Microbial DiseasesAlbany Medical CollegeAlbanyNew YorkUSA'], 'affiliations': [{'raw_affiliation_string': 'Center for Immunology and Microbial DiseasesAlbany Medical CollegeAlbanyNew YorkUSA', 'institution_ids': ['https://openalex.org/I77920804']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061372270', 'display_name': 'Mohamed Trebak', 'orcid': 'https://orcid.org/0000-0001-6759-864X'}, 'institutions': [{'id': 'https://openalex.org/I77920804', 'display_name': 'Albany Medical Center Hospital', 'ror': 'https://ror.org/0307crw42', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I77920804']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mohamed Trebak', 'raw_affiliation_strings': ['Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA'], 'affiliations': [{'raw_affiliation_string': 'Center for Cardiovascular SciencesAlbany Medical CollegeAlbanyNew YorkUSA', 'institution_ids': ['https://openalex.org/I77920804']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.96, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 161, 'citation_normalized_percentile': {'value': 0.999386, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '27', 'issue': '1', 'first_page': '63', 'last_page': '75'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10423', 'display_name': 'Neurobiology and Insect Physiology Research', 'score': 0.9921, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10035', 'display_name': 'Phytochemicals and Antioxidant Activities', 'score': 0.9807, 'subfield': {'id': 'https://openalex.org/subfields/2704', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C84606932', 'wikidata': 'https://www.wikidata.org/wiki/Q416496', 'display_name': 'Estrogen receptor', 'level': 4, 'score': 0.7392761}, {'id': 'https://openalex.org/C555283112', 'wikidata': 'https://www.wikidata.org/wiki/Q1637543', 'display_name': 'Carcinogenesis', 'level': 3, 'score': 0.6888146}, {'id': 'https://openalex.org/C2777164284', 'wikidata': 'https://www.wikidata.org/wiki/Q277954', 'display_name': 'Estrogen', 'level': 2, 'score': 0.60598075}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.47140077}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.46189368}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.36999995}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.2920096}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2801665}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.25075006}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.16678879}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.14619246}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.14109707}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.095599234}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.07319987}], 'mesh': [{'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D047628', 'descriptor_name': 'Estrogen Receptor alpha', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047628', 'descriptor_name': 'Estrogen Receptor alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061986', 'descriptor_name': 'MCF-7 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016513', 'descriptor_name': 'Mice, SCID', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1096/fj.12-213801', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S25293849', 'display_name': 'The FASEB Journal', 'issn_l': '0892-6638', 'issn': ['0892-6638', '1530-6860'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3528310', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528310', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22993197', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3528310', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.57, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'HL‐095566'}], 'datasets': [], 'versions': [], 'referenced_works_count': 46, 'referenced_works': ['https://openalex.org/W1495215957', 'https://openalex.org/W1575476642', 'https://openalex.org/W163483997', 'https://openalex.org/W1963703355', 'https://openalex.org/W1964287631', 'https://openalex.org/W1978593035', 'https://openalex.org/W1982620047', 'https://openalex.org/W1985767202', 'https://openalex.org/W1986531910', 'https://openalex.org/W1989108095', 'https://openalex.org/W1993781709', 'https://openalex.org/W2003189203', 'https://openalex.org/W2005700813', 'https://openalex.org/W2010140681', 'https://openalex.org/W2012915718', 'https://openalex.org/W2015480034', 'https://openalex.org/W2015946977', 'https://openalex.org/W2016348702', 'https://openalex.org/W2020033048', 'https://openalex.org/W2026656163', 'https://openalex.org/W2031966403', 'https://openalex.org/W2041383551', 'https://openalex.org/W2041748354', 'https://openalex.org/W2043250054', 'https://openalex.org/W2047655212', 'https://openalex.org/W2056042025', 'https://openalex.org/W2066603202', 'https://openalex.org/W2070832223', 'https://openalex.org/W2074922566', 'https://openalex.org/W2084897495', 'https://openalex.org/W2086264391', 'https://openalex.org/W2089040449', 'https://openalex.org/W2091626869', 'https://openalex.org/W2094864024', 'https://openalex.org/W2101586949', 'https://openalex.org/W2102285555', 'https://openalex.org/W2112645751', 'https://openalex.org/W2126692145', 'https://openalex.org/W2132781656', 'https://openalex.org/W2141015134', 'https://openalex.org/W2146066778', 'https://openalex.org/W2146341872', 'https://openalex.org/W2158331725', 'https://openalex.org/W2163789582', 'https://openalex.org/W2173877678', 'https://openalex.org/W2799503982'], 'related_works': ['https://openalex.org/W4252776767', 'https://openalex.org/W3209895153', 'https://openalex.org/W3010551324', 'https://openalex.org/W2364285896', 'https://openalex.org/W2171150728', 'https://openalex.org/W2117019370', 'https://openalex.org/W2087504465', 'https://openalex.org/W2028354452', 'https://openalex.org/W200925908', 'https://openalex.org/W1982850748'], 'abstract_inverted_index': {'Store-operated': [0], 'Ca2+': [1, 84, 86, 130, 252], 'entry': [2], '(SOCE)': [3], 'encoded': [4], 'by': [5, 108, 147, 154, 169], 'Orai1': [6], 'proteins': [7], 'is': [8, 247], 'a': [9, 220], 'ubiquitous': [10], 'Ca2+-selective': [11], 'conductance': [12], 'involved': [13], 'in': [14, 30, 50, 91, 99, 120, 203, 208], 'cellular': [15], 'proliferation': [16], 'and': [17, 43, 45, 65, 81, 118, 127, 149, 180, 219], 'migration.': [18], 'We': [19], 'recently': [20], 'described': [21], 'up-regulation': [22], 'of': [23, 48, 97, 111, 142, 161, 185], 'Orai3': [24, 44, 49, 61, 116, 137, 172, 197, 214, 246], 'channels': [25], 'that': [26, 57, 254], 'selectively': [27, 174], 'mediate': [28], 'SOCE': [29, 78, 98, 119], 'estrogen': [31, 249], 'receptor': [32, 250], 'α-expressing': [33], '(ERα+)': [34], 'breast': [35, 227], 'cancer': [36], 'cells.': [37, 94, 122, 195], 'However,': [38], 'the': [39, 46, 82], 'connection': [40], 'between': [41], 'ERα': [42, 58, 74, 103, 113], 'role': [47], 'tumorigenesis': [51, 202], 'remain': [52], 'unknown.': [53], 'Here,': [54], 'we': [55], 'show': [56], 'knockdown': [59, 75, 104, 138, 173, 198], 'decreases': [60, 76], 'mRNA': [62], '(by': [63, 67, 79, 89, 178, 183], '~63%)': [64], 'protein': [66], '~44%)': [68, 148, 184], 'with': [69, 189], 'no': [70, 190], 'effect': [71, 191], 'on': [72, 102, 192], 'Orai1.': [73], 'Orai3-mediated': [77], '~43%)': [80], 'corresponding': [83], 'release-activated': [85], '(CRAC)': [87], 'current': [88], '~42%)': [90], 'ERα+': [92, 186, 200, 226], 'MCF7': [93, 100, 121, 133, 187], 'The': [95], 'abrogation': [96], 'cells': [101, 134, 167, 188], 'can': [105], 'be': [106], 'rescued': [107], 'ectopic': [109], 'expression': [110, 117], 'Orai3.': [112, 136], 'activation': [114], 'increased': [115], 'Epidermal': [123], 'growth': [124, 177], 'factor': [125, 163], '(EGF)': [126], 'thrombin': [128], 'stimulate': [129], 'influx': [131], 'into': [132], 'through': [135], 'inhibited': [139, 199], 'SOCE-dependent': [140], 'phosphorylation': [141], 'extracellular': [143], 'signal-regulated': [144], 'kinase': [145, 152], '(ERK1/2;': [146], 'focal': [150], 'adhesion': [151], '(FAK;': [153], '~46%)': [155], 'as': [156, 158, 215], 'well': [157], 'transcriptional': [159], 'activity': [160], 'nuclear': [162], 'for': [164, 225], 'activated': [165], 'T': [166], '(NFAT;': [168], '~49%).': [170], 'Significantly,': [171], 'decreased': [175], 'anchorage-independent': [176], '~58%)': [179], 'Matrigel': [181], 'invasion': [182], 'ERα–': [193], 'MDA-MB231': [194], 'Moreover,': [196], 'cell': [201], 'immunodeficient': [204], 'mice': [205], '(~66%': [206], 'reduction': [207], 'tumor': [209], 'volume).': [210], 'These': [211], 'data': [212], 'establish': [213], 'an': [216, 248], 'ERα-regulated': [217], 'channel': [218, 253], 'potential': [221], 'selective': [222], 'therapeutic': [223], 'target': [224], 'cancers.—Motiani,': [228], 'R.': [229, 237], 'K.,': [230, 240], 'Zhang,': [231], 'X.,': [232], 'Harmon,': [233], 'K.': [234], 'E.,': [235], 'Keller,': [236], 'S.,': [238], 'Matrougui,': [239], 'Bennett,': [241], 'J.': [242, 258], 'A.,': [243], 'Trebak,': [244], 'M.': [245], 'α-regulated': [251], 'promotes': [255], 'tumorigenesis.': [256], 'FASEB': [257], '27,': [259], '63–75': [260], '(2013).': [261], 'www.fasebj.org': [262]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1985924867', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 23}, {'year': 2019, 'cited_by_count': 13}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 12}, {'year': 2015, 'cited_by_count': 17}, {'year': 2014, 'cited_by_count': 18}, {'year': 2013, 'cited_by_count': 13}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-04T02:41:58.981607', 'created_date': '2016-06-24'}