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[379], 'hematology': [381], 'clinics': [382], 'Ankara,': [385], 'Izmir,': [386], 'Adana,': [387], 'Antalya.': [389], 'The': [390, 418, 571, 601, 1097, 1123, 1172, 1199, 1237, 1304], 'determination': [391], 'pathology': [395], '754': [397], '42': [400], 'abnormal': [401], 'hemoglobin': [402, 645], 'genes': [403], 'frequency': [408, 456, 1173], 'distribution': [409], 'six': [411], 'distinct': [412], 'regions': [413], 'was': [416], 'accomplished.': [417], 'experimental': [419], 'strategy,': [420], 'based': [421], 'on': [422, 644, 1101, 1308], 'PCR': [423], 'amplification': [424, 848], 'β-globin': [427, 1265, 1468, 1532], 'gene,': [428], 'included': [429], 'dot-blot': [430], 'hybridization': [431, 812], '18': [433, 1030], 'probes': [434], 'specific': [435], 'Mediterranean': [438, 987], 'populations,': [439], 'denaturing': [440, 883], 'gradient': [441, 884], 'gel': [442, 885], 'electrophoresis,': [443], 'genomic': [445], 'sequencing.': [446], 'When': [447], 'regional': [449], 'results': [450], 'are': [451, 476], 'compared': [452], 'overall': [455, 482], 'mutations': [458, 498, 547, 972, 1082, 1177, 1203, 1239, 1259], 'country,': [461], 'it': [462], 'is': [463], 'observed': [464], 'that': [465], 'frequencies': [467], 'western': [470, 657], 'southern': [472, 1290], 'parts': [473, 489], 'good': [478], 'accordance': [479], 'distribution,': [483], 'whereas': [484], 'northern': [486], 'eastern': [488], 'region/population-specific': [493], 'profile': [494], 'some': [496], 'rare': [497], 'having': [499], 'significantly': [501], 'high': [502], 'occurrence': [503], 'these': [505], 'regions.': [506], 'Further': [507], 'evaluation': [508], 'data': [511], 'respect': [513], 'region-': [515], 'or': [516], 'population-dependent': [517], 'differences': [518], 'will': [519], 'contribute': [520], 'better': [523], 'understanding': [524], 'mechanisms': [527], 'leading': [528], 'marked': [531], 'heterogeneity': [533], 'Turkey,': [535], 'but': [536], 'could': [537], 'also': [538], 'be': [539], 'extremely': [540], 'valuable': [541], 'facilitating': [543], 'rapid': [544], 'identification': [545], 'families': [549], 'at': [550], 'risk': [551], 'different': [553], 'hemoglobinopathies.': [554], 'Am.': [555], 'J.': [556], 'Hematol.': [557], '57:215–220,': [558], '1998.': [559], '©': [560], 'Wiley-Liss,': [562], 'Inc.': [563], 'References': [564], '1': [565], 'Weatherall': [566], 'DJ,': [567], 'Clegg': [568], 'JB:': [569], '"': [570, 1096, 1303], 'Thalassemia': [572], 'Syndromes."': [573], 'Oxford:': [574], 'Blackwell': [575], 'Scientific': [576], 'Publications,': [577], '1981.': [578, 1272], '2': [579], 'WHO:': [580], 'Community': [581], 'Control': [582], 'Hereditary': [584], 'Anemias:': [585], 'Memorandum': [586], 'From': [587], 'WHO': [589, 592], 'Meeting.': [590], 'Bulletin': [591], '61:': [593], '63,': [594], '1983.': [595], 'Baysal': [597, 1041, 1213, 1339], 'E,': [598, 696, 965, 1042, 1214, 1222, 1340], 'Carver': [599], 'MFH:': [600], 'β-': [602], 'δ-Thalassemia': [604], 'Repository': [605], '(8': [606], 'th': [607], 'ed.).': [608], 'Hemoglobin': [609, 710, 992, 1026, 1161, 1182, 1441, 1476, 1509, 1540, 1560], '19:': [610, 1183], '213,': [611], '1995.': [612, 685, 1185], '4': [613], 'Kazazian': [614, 750, 1367], 'HH': [615, 751, 1368], 'Jr,': [616], 'Boehm': [617, 748], 'CD:': [618], 'basis': [620, 671, 1125], 'prenatal': [622, 673, 1086, 1132], 'diagnosis': [623, 674, 1087], 'β-thalassemia.': [625], 'Blood': [626, 819, 1134], '72:': [627], '1107,': [628], '1988.': [629, 738, 775, 822, 945], '5': [630], 'Aksoy': [631, 789, 966, 1545, 1558, 1576], 'M,': [632, 688, 716, 790, 861, 1066, 1076, 1142, 1192, 1228, 1330, 1387, 1389, 1399, 1577], 'Kutlar': [633, 635, 785, 787, 1013, 1015, 1335, 1582, 1584], 'A,': [634, 786, 794, 827, 955, 963, 1004, 1014, 1070, 1220, 1230, 1277, 1328, 1360, 1397, 1415, 1449, 1517, 1583], 'F,': [636, 788, 895, 1016, 1336, 1585], 'Dinçol': [637, 952], 'G,': [638, 953, 998, 1218, 1281, 1366], 'Erdem': [639], 'S,': [640, 897, 1012, 1279, 1395, 1486], 'Bastesbihçi': [641], 'S:': [642, 698], 'Survey': [643], 'variants,': [646], 'β+-thalassemia,': [647], 'glucose-6-phosphate': [648], 'dehydrogenase': [649], 'deficiency': [650], 'haptoglobin': [652], 'types': [653, 810], 'Turks': [655], 'Thrace.': [658], 'J': [659, 680, 771, 887, 976, 1207, 1246, 1267, 1599], 'Med': [660, 772, 888], 'Genet': [661, 889, 1056, 1209, 1350, 1409], '22:': [662], '288,': [663], '1985.': [664], '6': [665], 'Altay': [666, 791], 'CL,': [667, 792], 'Baslak': [668], 'AN:': [669], 'hemoglobinopathies': [676], 'Turkey.': [678, 974, 1552], 'Int': [679, 975], 'Pediat': [681], 'Hematol/Oncol': [682], '2:': [683, 1378], '283,': [684], '7': [686], 'Poncz': [687], 'Solowiejczky': [689], 'D,': [690, 1072, 1421], 'Harpel': [691], 'B,': [692, 951, 1010, 1144, 1383, 1453, 1488, 1519], 'Mory': [693], 'Y,': [694, 796, 957, 1234, 1575], 'Schwartz': [695], 'Surrey': [697], 'Construction': [699], 'human': [701, 730], 'gene': [702, 1469, 1533], 'libraries': [703], 'small': [705], 'amounts': [706], 'peripheral': [708], 'blood.': [709], '6:': [711], '27,': [712], '1982.': [713], '8': [714], 'Miller': [715, 1067], 'Dykes': [717], 'DD,': [718], 'Polesky': [719], 'HF:': [720], 'A': [721, 1456, 1491, 1522], 'simple': [722], 'salting': [723], 'out': [724], 'procedure': [725], 'extracting': [727], 'DNA': [728, 763, 815, 900, 922], 'nucleated': [731], 'cells.': [732], 'Nucleic': [733, 853], 'Acids': [734, 854], 'Res': [735, 855], '16:': [736, 1477], '1215,': [737], '9': [739], 'Saiki': [740], 'RK,': [741], 'Chang': [742], 'CA,': [743], 'Levenson': [744], 'CH,': [745], 'Warren': [746], 'TC,': [747], 'CD,': [749, 1036], 'Jr:': [752, 1369], 'Diagnosis': [753], 'enzymatically': [761], 'amplified': [762, 814], 'nonradioactive': [765], 'allele-specific': [766], 'oligonucleotide': [767], 'probes.': [768, 818], 'N': [769], 'Engl': [770], '319:': [773], '537,': [774], '10': [776], 'Diaz-Chico': [777], 'JC,': [778, 837], 'Yang': [779], 'KG,': [780], 'Stoming': [781, 1019, 1432], 'TA,': [782, 1020, 1433], 'Efremov': [783, 999, 1001, 1416, 1434], 'GD,': [784, 1000, 1435], 'Gürgey': [793], 'Kilinç': [795, 956, 1574], 'Huisman': [797, 982, 1021, 1047, 1235, 1341, 1400, 1436, 1586], 'THJ:': [798, 983, 1022, 1048, 1236, 1342, 1401, 1437, 1587], 'Mild': [799], 'severe': [801], 'among': [803, 1591], 'homozygotes': [804], 'Turkey:': [806], 'Identification': [807], 'synthetic': [817], '71:': [820], '248,': [821], '11': [823], 'Newton': [824], 'CR,': [825], 'Graham': [826], 'Heptinstall': [828], 'LE,': [829], 'Powell': [830], 'SJ,': [831], 'Summers': [832], 'C,': [833, 1196, 1283, 1362], 'Kalsheker': [834], 'N,': [835, 1423, 1425, 1427], 'Smith': [836], 'Markham': [838], 'AF:': [839], 'Analysis': [840], 'any': [842], 'point': [843], 'mutation': [844, 850], 'DNA;': [846], 'refractory': [849], 'system': [851], '(ARMS).': [852], '17:': [856, 1510, 1541], '2503,': [857], '1989.': [858], '12': [859], 'Losekoot': [860], 'van': [862], 'Heeren': [863], 'H,': [864, 959, 1451, 1482], 'Schipper': [865], 'JJ,': [866], 'Giordano': [867], 'PC,': [868], 'Bernini': [869], 'LF,': [870], 'Fodde': [871], 'R:': [872, 1287], 'Rapid': [873], 'detection': [874], 'highly': [877], 'polymorphic': [878], 'beta': [879], 'globin': [880], 'framework': [881], 'electrophoresis.': [886], '29:': [890], '574,': [891], '1992.': [892, 1059, 1250, 1353, 1479], '13': [893, 1524], 'Sanger': [894], 'Nicklen': [896], 'Coulson': [898], 'AR:': [899, 1171], 'sequencing': [901, 933], 'chain': [903, 926], 'terminating': [904], 'inhibitors.': [905], 'Proc': [906, 938], 'Natl': [907, 939], 'Acad': [908, 940], 'Sci': [909, 941], 'USA': [910, 942], '74:': [911], '5463,': [912], '1977.': [913], '14': [914, 1175], 'Gyllensten': [915], 'UB,': [916], 'Erlich': [917], 'HA:': [918], 'Generation': [919], 'single-stranded': [921], 'polymerase': [925], 'reaction': [927], 'its': [929], 'application': [930, 1084], 'direct': [932, 1503], 'HLA-DQA': [936], 'locus.': [937], '85:': [943], '7652,': [944], '15': [946], 'Atalay': [947, 954], 'EÖ,': [948], 'Clirakog': [949], 'lu': [950], 'Aytekin': [958], 'Yüregir': [960, 1033, 1231, 1578], 'GT,': [961, 1034, 1232, 1429, 1579], 'Arpaci': [962], 'Bermek': [964], 'M:': [967, 1078, 1546, 1559], 'Regional': [968], 'distributions': [969], 'Hematol': [977], '57:': [978], '207,': [979], '1993.': [980, 1110, 1317, 1380, 1412, 1512, 1543], '16': [981], 'four': [986], 'countries;': [988], 'an': [989], 'editorial': [990], 'commentary.': [991], '14:': [993, 1027, 1442], '35,': [994], '1990.': [995, 1029, 1444], '17': [996], 'Petkov': [997, 1428], 'DG,': [1002, 1417], 'Dimovski': [1003, 1414], 'Tchaicarova': [1005], 'P,': [1006, 1226], 'Tchaicarov': [1007], 'R,': [1008, 1074, 1190, 1194], 'Rogina': [1009], 'Agarwal': [1011], 'Reese': [1017, 1430], 'AL,': [1018, 1431], 'Bulgaria.': [1025], '25,': [1028], 'Çürük': [1031], 'MA,': [1032], 'Asadov': [1035], 'Dadasova': [1037], 'T,': [1038], 'Gu': [1039, 1043, 1337], 'L,': [1040, 1062, 1068, 1188, 1275, 1326, 1419], 'YS,': [1044], 'Ribeiro': [1045], 'ML,': [1046], 'characterization': [1050, 1344, 1371, 1403], 'bthalassemia': [1052, 1081, 1261], 'Azerbaijan.': [1054], 'Hum': [1055, 1208, 1349, 1376, 1408], '90:': [1057], '417,': [1058], '19': [1060], 'Varnavides': [1061], 'Old': [1063, 1197, 1223], 'J,': [1064, 1324, 1332], 'Mitchell': [1065], 'Fitches': [1069], 'Valler': [1071], 'Karimi-Nejad': [1073, 1077], 'Layton': [1075], 'Screening': [1079], 'Iranian': [1090], 'population.': [1091], 'P': [1093, 1300], 'Ioannou': [1094, 1225, 1301], '(ed):': [1095, 1302], '5th': [1098, 1305], 'International': [1099, 1306], 'Conference': [1100, 1307], 'Thalassaemias': [1102, 1309], 'Haemoglobinopathies."': [1105, 1312], 'Geneva:': [1106, 1313], 'World': [1107, 1314], 'Health': [1108, 1315], 'Organization,': [1109, 1316], '20': [1111], 'Chehab': [1112], 'FF,': [1113], 'Der': [1114], 'Kaloustian': [1115], 'V,': [1116, 1285, 1322, 1391], 'Khouri': [1117], 'FP,': [1118], 'Deeb': [1119], 'SS,': [1120], 'Kan': [1121], 'YW:': [1122], 'Lebanon:': [1129], 'Application': [1130], 'diagnosis.': [1133], '69:': [1135], '1141,': [1136], '1987.': [1137], '21': [1138], 'Waye': [1139], 'JS,': [1140], 'Patterson': [1141], 'Eng': [1143], 'Scully': [1145], 'MF:': [1146], 'intermedia': [1148], 'Lebanese': [1151], 'child': [1152], 'due': [1153], 'homozygosity': [1155], '-88': [1158], '(C-T)': [1159], 'mutation.': [1160], '18:': [1162], '383,': [1163], '1994.': [1164], '22': [1165], 'El-Hazmi': [1166], 'MAF,': [1167], 'Warsy': [1168], 'AS,': [1169], 'Al-Swailem': [1170], 'Arab': [1180], 'populations.': [1181], '353,': [1184], '23': [1186], 'Zahed': [1187], 'Talhouk': [1189], 'Saleh': [1191], 'Abou-Jaoudeh': [1193], 'Fisher': [1195], 'J:': [1198], 'spectrum': [1200], 'Lebanon.': [1205], 'Eur': [1206], '(in': [1210], 'press).': [1211], '24': [1212], 'Indrak': [1215, 1319, 1392], 'K,': [1216, 1320, 1393], 'Bozkurt': [1217], 'Berkalp': [1219], 'Ariktan': [1221], 'JM,': [1224], 'Angastiniotis': [1227], 'Droushiuotou': [1229], 'Kilinc,': [1233], 'cyprus.': [1244], 'Br': [1245, 1598], 'Haematol': [1247, 1600], '81:': [1248], '607,': [1249], '25': [1251], 'Orkin': [1252], 'SH,': [1253], 'Goff': [1254], 'SC:': [1255], 'Nonsense': [1256], 'frameshift': [1258, 1458], 'detected': [1262, 1499], 'cloned': [1264], 'genes.': [1266], 'Biol': [1268], 'Chem': [1269], '256:': [1270], '9782,': [1271], '26': [1273], 'Pagano': [1274], 'Viola': [1276], 'Desicato': [1278], 'Fioretti': [1280], 'Matero': [1282], 'Rametta': [1284], 'Cimino': [1286], 'Italy:': [1291], 'Relationship': [1292], 'between': [1293], 'phenotype': [1294], 'genotype': [1296], 'heterozygotes.': [1298], '27': [1318], 'Brabec': [1321], 'Indrakova': [1323], 'Chrobak': [1325], 'Sakalov': [1327], 'Jarosova': [1329], 'Crermok': [1331], 'Fei': [1333], 'YJ,': [1334], 'YC,': [1338], 'Czechoslovakia.': [1348], '88:': [1351], '399,': [1352], '28': [1354], 'Hussein': [1355], 'IR,': [1356], 'Temtamy': [1357], 'SA,': [1358], 'El-Beshlawy': [1359], 'Fearon': [1361], 'Shalaby': [1363], 'Z,': [1364], 'Vassilopoulos': [1365], 'Egyptians.': [1375], 'Mutat': [1377], '48,': [1379], '29': [1381], 'Ringelhann': [1382], 'Szelenyi': [1384], 'JG,': [1385], 'Horanyi': [1386], 'Svobodova': [1388], 'Divoky': [1390], 'Hollan': [1394], 'Marosi': [1396], 'Laub': [1398], 'Hungary.': [1407], '92:': [1410], '385,': [1411], '30': [1413], 'Jankovic': [1418], 'Juricic': [1420], 'Zisovski': [1422], 'Stojanovski': [1424], 'Nikolov': [1426], 'Yugoslavia.': [1440], '15,': [1443], '31': [1445], 'Basak': [1446, 1483, 1514], 'AN,': [1447, 1484, 1515], 'Ozcelik': [1450], 'Kirdar': [1452, 1487, 1518], 'Gurgey': [1454], 'A:': [1455], 'novel': [1457, 1492, 1523], 'mutation:': [1459], 'Deletion': [1460], 'C': [1462], 'codons': [1464], '74/75': [1465], 'causes': [1470, 1534], 'β°-thalassemia': [1471], 'patient.': [1475, 1539], '309,': [1478], '32': [1480], 'Özcelik': [1481], 'Akar': [1489, 1520], 'N:': [1490, 1521], 'deletion': [1493, 1526], 'patient': [1498], 'DGGE': [1501], 'sequencing:': [1504], 'FSC': [1505], '22–24': [1506], '(-7': [1507], 'bp).': [1508], '387,': [1511], '33': [1513], 'Bp': [1525], '38UTR': [1529], '551,': [1542], '34': [1544], 'Sickle': [1547, 1588], 'trait': [1549], 'South': [1551], 'Lancet': [1553], '1:': [1554], '589,': [1555], '1955.': [1556], '35': [1557], 'S': [1561], 'E': [1563], 'people.': [1566], 'Nature': [1567], '193:': [1568], '786,': [1569], '1961.': [1570], '36': [1571], 'Aluoch': [1572], 'JR,': [1573], 'Bakioglu': [1580], 'I,': [1581], 'anaemia': [1590], 'Eti-Turks:': [1592], 'Haematological,': [1593], 'clinical': [1594], 'observations.': [1597], '64:': [1601], '45,': [1602], '1986.': [1603], 'Citing': [1604], 'Literature': [1605], 'Volume57,': [1606], 'Issue3March': [1607], '1998Pages': [1608], 'ReferencesRelatedInformation': [1610]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1985830102', 'counts_by_year': [{'year': 2024, 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