Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1985679998', 'doi': 'https://doi.org/10.5858/arpa.2011-0463-oa', 'title': 'Lymphovascular Invasion in Micropapillary Urothelial Carcinoma: A Study of 22 Cases', 'display_name': 'Lymphovascular Invasion in Micropapillary Urothelial Carcinoma: A Study of 22 Cases', 'publication_year': 2012, 'publication_date': '2012-05-30', 'ids': {'openalex': 'https://openalex.org/W1985679998', 'doi': 'https://doi.org/10.5858/arpa.2011-0463-oa', 'mag': '1985679998', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22646270'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5858/arpa.2011-0463-oa', 'pdf_url': 'https://meridian.allenpress.com/aplm/article-pdf/136/6/635/1440864/arpa_2011-0463-oa.pdf', 'source': {'id': 'https://openalex.org/S139062638', 'display_name': 'Archives of Pathology & Laboratory Medicine', 'issn_l': '0003-9985', 'issn': ['0003-9985', '1543-2165'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://meridian.allenpress.com/aplm/article-pdf/136/6/635/1440864/arpa_2011-0463-oa.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004853028', 'display_name': 'Elizabeth McQuitty', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1295876152', 'display_name': 'Houston Methodist', 'ror': 'https://ror.org/027zt9171', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1295876152']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Elizabeth McQuitty', 'raw_affiliation_strings': ['Houston Methodist Research Institute'], 'affiliations': [{'raw_affiliation_string': 'Houston Methodist Research Institute', 'institution_ids': ['https://openalex.org/I1295876152']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020414083', 'display_name': 'Jae Y. Ro', 'orcid': 'https://orcid.org/0000-0002-4158-3658'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jae Y. Ro', 'raw_affiliation_strings': ['Academic Institute'], 'affiliations': [{'raw_affiliation_string': 'Academic Institute', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109288977', 'display_name': 'Luan D. Truong', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Luan D. Truong', 'raw_affiliation_strings': ['Academic Institute'], 'affiliations': [{'raw_affiliation_string': 'Academic Institute', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014453742', 'display_name': 'Steven S. Shen', 'orcid': 'https://orcid.org/0000-0001-7725-1260'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Steven S. Shen', 'raw_affiliation_strings': ['Academic Institute'], 'affiliations': [{'raw_affiliation_string': 'Academic Institute', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109975870', 'display_name': 'Qihui Zhai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I63135867', 'display_name': 'University of Cincinnati', 'ror': 'https://ror.org/01e3m7079', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I63135867']}, {'id': 'https://openalex.org/I1295876152', 'display_name': 'Houston Methodist', 'ror': 'https://ror.org/027zt9171', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1295876152']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Qihui Zhai', 'raw_affiliation_strings': ['Houston Methodist Research Institute', 'University of Cincinnati'], 'affiliations': [{'raw_affiliation_string': 'University of Cincinnati', 'institution_ids': ['https://openalex.org/I63135867']}, {'raw_affiliation_string': 'Houston Methodist Research Institute', 'institution_ids': ['https://openalex.org/I1295876152']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5020000559', 'display_name': 'Alberto G. Ayala', 'orcid': 'https://orcid.org/0000-0001-8613-9297'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Alberto G. Ayala', 'raw_affiliation_strings': ['Academic Institute'], 'affiliations': [{'raw_affiliation_string': 'Academic Institute', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.475, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.881127, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '136', 'issue': '6', 'first_page': '635', 'last_page': '639'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12695', 'display_name': 'Urinary and Genital Oncology Studies', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.99, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/lymphovascular-invasion', 'display_name': 'Lymphovascular invasion', 'score': 0.9768575}, {'id': 'https://openalex.org/keywords/tumor-budding', 'display_name': 'Tumor budding', 'score': 0.46297213}], 'concepts': [{'id': 'https://openalex.org/C2778740770', 'wikidata': 'https://www.wikidata.org/wiki/Q6708283', 'display_name': 'Lymphovascular invasion', 'level': 4, 'score': 0.9768575}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.713992}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.7000618}, {'id': 'https://openalex.org/C125473707', 'wikidata': 'https://www.wikidata.org/wiki/Q9914', 'display_name': 'H&E stain', 'level': 3, 'score': 0.5236815}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.49520937}, {'id': 'https://openalex.org/C2779188454', 'wikidata': 'https://www.wikidata.org/wiki/Q16948689', 'display_name': 'Tumor budding', 'level': 5, 'score': 0.46297213}, {'id': 'https://openalex.org/C181152851', 'wikidata': 'https://www.wikidata.org/wiki/Q712604', 'display_name': 'Lymphatic system', 'level': 2, 'score': 0.43283814}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42330205}, {'id': 'https://openalex.org/C3019882237', 'wikidata': 'https://www.wikidata.org/wiki/Q2501186', 'display_name': 'Urothelial carcinoma', 'level': 4, 'score': 0.4134783}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33203474}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.20414197}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.1692205}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.14754519}, {'id': 'https://openalex.org/C2992571226', 'wikidata': 'https://www.wikidata.org/wiki/Q170758', 'display_name': 'Lymph node metastasis', 'level': 4, 'score': 0.055459857}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.03595361}], 'mesh': [{'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D002291', 'descriptor_name': 'Carcinoma, Papillary', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D014571', 'descriptor_name': 'Urologic Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D019459', 'descriptor_name': 'Urothelium', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002291', 'descriptor_name': 'Carcinoma, Papillary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008207', 'descriptor_name': 'Lymphatic Metastasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014571', 'descriptor_name': 'Urologic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019459', 'descriptor_name': 'Urothelium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.5858/arpa.2011-0463-oa', 'pdf_url': 'https://meridian.allenpress.com/aplm/article-pdf/136/6/635/1440864/arpa_2011-0463-oa.pdf', 'source': {'id': 'https://openalex.org/S139062638', 'display_name': 'Archives of Pathology & Laboratory Medicine', 'issn_l': '0003-9985', 'issn': ['0003-9985', '1543-2165'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22646270', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5858/arpa.2011-0463-oa', 'pdf_url': 'https://meridian.allenpress.com/aplm/article-pdf/136/6/635/1440864/arpa_2011-0463-oa.pdf', 'source': {'id': 'https://openalex.org/S139062638', 'display_name': 'Archives of Pathology & Laboratory Medicine', 'issn_l': '0003-9985', 'issn': ['0003-9985', '1543-2165'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.41}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W1748831360', 'https://openalex.org/W1970425408', 'https://openalex.org/W1977780578', 'https://openalex.org/W1983690825', 'https://openalex.org/W1998100539', 'https://openalex.org/W2000473495', 'https://openalex.org/W2005272666', 'https://openalex.org/W2010053111', 'https://openalex.org/W2025049256', 'https://openalex.org/W2027916998', 'https://openalex.org/W2028028908', 'https://openalex.org/W2036071158', 'https://openalex.org/W2047411533', 'https://openalex.org/W2048691504', 'https://openalex.org/W2065737246', 'https://openalex.org/W2077122266', 'https://openalex.org/W2079656051', 'https://openalex.org/W2080200957', 'https://openalex.org/W2093575898', 'https://openalex.org/W2117178403', 'https://openalex.org/W2125506656', 'https://openalex.org/W2128164226', 'https://openalex.org/W2132528079', 'https://openalex.org/W2160320035'], 'related_works': ['https://openalex.org/W4315644619', 'https://openalex.org/W4200144588', 'https://openalex.org/W3084422596', 'https://openalex.org/W3007911350', 'https://openalex.org/W2996500276', 'https://openalex.org/W2921360770', 'https://openalex.org/W2799852344', 'https://openalex.org/W2339204668', 'https://openalex.org/W2265622296', 'https://openalex.org/W2082857199'], 'abstract_inverted_index': {'Micropapillary': [0], 'urothelial': [1, 10, 164], 'carcinoma': [2], '(MPUC)': [3], 'is': [4], 'a': [5, 150], 'known': [6], 'aggressive': [7], 'variant': [8], 'of': [9, 23, 29, 100, 103, 135, 146, 163], 'carcinoma.': [11, 165], 'However,': [12, 124], 'the': [13, 21, 58, 98, 144], 'reasons': [14], 'for': [15, 54, 94, 153], 'its': [16], 'aggressiveness': [17], 'remain': [18], 'unclear.To': [19], 'investigate': [20], 'frequency': [22], 'lymphovascular': [24, 41, 55, 72, 95, 109, 122, 136, 154], 'invasion': [25, 56, 73, 80, 96, 110, 137, 155], 'in': [26, 130], '22': [27, 67], 'cases': [28, 87], 'MPUC.Consecutive': [30], 'tissue': [31], 'sections': [32], 'were': [33, 50, 88], 'stained': [34], 'with': [35, 44, 77], 'D2-40': [36], 'and': [37, 65, 81, 156], 'CD34': [38], 'to': [39], 'highlight': [40], 'channels': [42], 'associated': [43], 'MPUC.': [45], 'Spaces': [46], 'containing': [47], 'tumor': [48], 'cells': [49], 'scored': [51], 'as': [52, 92, 149, 158], 'positive': [53], 'if': [57], 'staining': [59], 'pattern': [60], 'on': [61, 74, 97, 112], 'immunohistochemistry': [62], 'was': [63], 'distinct': [64], 'circumferential.Of': [66], 'cases,': [68], '21': [69], '(95%)': [70], 'had': [71, 107], 'immunohistochemical': [75, 113, 139], 'staining,': [76], '91%': [78], 'lymphatic': [79], '4%': [82], 'vascular': [83], 'invasion.': [84], 'Interestingly,': [85], '8': [86], 'originally': [89], 'signed': [90], 'out': [91], 'negative': [93], 'basis': [99], 'hematoxylin-eosin-stained': [101], 'sections;': [102], 'these,': [104], '7': [105], '(88%)': [106], 'focal': [108], 'evident': [111], 'staining.Our': [114], 'results': [115], 'confirm': [116], 'that': [117], 'micropapillary': [118, 147], 'lacunae': [119], 'are': [120], 'not': [121], 'channels.': [123], 'nearly': [125], 'all': [126], 'MPUC': [127, 157], 'tumors': [128], '(95%': [129], 'this': [131], 'series)': [132], 'have': [133], 'evidence': [134], 'by': [138], 'analysis.': [140], 'Our': [141], 'data': [142], 'support': [143], 'use': [145], 'features': [148], 'morphologic': [151], 'marker': [152], 'an': [159], 'adverse': [160], 'histologic': [161], 'type': [162]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1985679998', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 3}], 'updated_date': '2024-12-14T06:39:45.848446', 'created_date': '2016-06-24'}