Title: Bacterial Superantigens—Mechanism of T Cell Activation by the Superantigens and Their Role in the Pathogenesis of Infectious Diseases
Abstract: Microbiology and ImmunologyVolume 38, Issue 4 p. 245-256 MinireviewFree Access Bacterial Superantigens—Mechanism of T Cell Activation by the Superantigens and Their Role in the Pathogenesis of Infectious Diseases Takehiko Uchiyama, Corresponding Author Takehiko Uchiyama Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanAddress correspondence to Dr. Takehiko Uchiyama, Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, 8-1 Kawadacho, Shinjuku-ku, Tokyo 162, Japan.Search for more papers by this authorXiao-jie Yan, Xiao-jie Yan Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanSearch for more papers by this authorKen'ichi Imanishi, Ken'ichi Imanishi Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanSearch for more papers by this authorJunji Yagi, Junji Yagi Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanSearch for more papers by this author Takehiko Uchiyama, Corresponding Author Takehiko Uchiyama Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanAddress correspondence to Dr. Takehiko Uchiyama, Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, 8-1 Kawadacho, Shinjuku-ku, Tokyo 162, Japan.Search for more papers by this authorXiao-jie Yan, Xiao-jie Yan Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanSearch for more papers by this authorKen'ichi Imanishi, Ken'ichi Imanishi Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanSearch for more papers by this authorJunji Yagi, Junji Yagi Department of Microbiology and Immunology, School of Medicine, Tokyo Women's Medical College, Shinjuku-ku, Tokyo, 162 JapanSearch for more papers by this author First published: April 1994 https://doi.org/10.1111/j.1348-0421.1994.tb01772.xCitations: 71AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abbreviations AC accessory cells mAb monoclonal antibody MHC major histocompatibility complex SE staphylococcal enterotoxins SEA~SEE staphylococcal enterotoxins A~E SPE streptococcal pyrogenic exotoxins SSA streptococcal superantigen TCR T cell receptors for conventional immunogens TSS toxic shock syndrome TSST-1 toxic shock syndrome toxin-1 YPM Yersinia pseudotuberculosis-derived mitogen. References 1Abe, J., Forrester, J., Nakahara, T., Lafferty, J.A., Kotzin, B.L., and Leung, D. Y. M. 1991. Selective stimulation of human T cells with streptococcal erythrogenic toxins A and B. J. Immunol. 146: 3747– 3750. CASPubMedWeb of Science®Google Scholar 2Abe, J., Kotzin, B.L., Jujo, K., Melish, M.E., Glode, M.P., Kohsaka, T., and Leung, D. Y. M. 1992. Selective expansion of T-cells expressing T cell receptor variable regions Vβ2 and Vβ8 in Kawasaki disease. Proc. Natl. Acad. Sci. U. S. A. 89: 4066– 4070. 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