Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1983972036', 'doi': 'https://doi.org/10.1002/(sici)1520-6394(1997)6:4<170::aid-da7>3.0.co;2-g', 'title': 'Open-label pilot study of tramadol hydrochloride in treatment-refractory obsessive-compulsive disorder', 'display_name': 'Open-label pilot study of tramadol hydrochloride in treatment-refractory obsessive-compulsive disorder', 'publication_year': 1997, 'publication_date': '1997-01-01', 'ids': {'openalex': 'https://openalex.org/W1983972036', 'doi': 'https://doi.org/10.1002/(sici)1520-6394(1997)6:4<170::aid-da7>3.0.co;2-g', 'mag': '1983972036', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9559288'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/(sici)1520-6394(1997)6:4<170::aid-da7>3.0.co;2-g', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S192592622', 'display_name': 'Depression and Anxiety', 'issn_l': '1091-4269', 'issn': ['1091-4269', '1520-6394'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056646383', 'display_name': 'Nathan A. Shapira', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nathan A. Shapira', 'raw_affiliation_strings': ['University of Cincinnati College of Medicine, Department of Psychiatry, P.O. Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267‐0559.'], 'affiliations': [{'raw_affiliation_string': 'University of Cincinnati College of Medicine, Department of Psychiatry, P.O. Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267‐0559.', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113621957', 'display_name': 'Paul E. Keck', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paul E. Keck', 'raw_affiliation_strings': ['Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio'], 'affiliations': [{'raw_affiliation_string': 'Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052335477', 'display_name': 'Toby D. Goldsmith', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Toby D. Goldsmith', 'raw_affiliation_strings': ['Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio'], 'affiliations': [{'raw_affiliation_string': 'Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109861966', 'display_name': 'Brian J. McConville', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Brian J. McConville', 'raw_affiliation_strings': ['Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio'], 'affiliations': [{'raw_affiliation_string': 'Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053958229', 'display_name': 'Michael Eis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael Eis', 'raw_affiliation_strings': ['Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio'], 'affiliations': [{'raw_affiliation_string': 'Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5079329164', 'display_name': 'Susan L. McElroy', 'orcid': 'https://orcid.org/0000-0002-8879-0865'}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Susan L. McElroy', 'raw_affiliation_strings': ['Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio'], 'affiliations': [{'raw_affiliation_string': 'Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio', 'institution_ids': ['https://openalex.org/I92156820']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2300, 'currency': 'USD', 'value_usd': 2300, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.571, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 81, 'citation_normalized_percentile': {'value': 0.946299, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '6', 'issue': '4', 'first_page': '170', 'last_page': '173'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11123', 'display_name': 'Obsessive-Compulsive Spectrum Disorders', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/3203', 'display_name': 'Clinical Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11123', 'display_name': 'Obsessive-Compulsive Spectrum Disorders', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/3203', 'display_name': 'Clinical Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, {'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11071', 'display_name': 'Treatment of Major Depression', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.53293717}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42540172}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.4096345}], 'mesh': [{'descriptor_ui': 'D000701', 'descriptor_name': 'Analgesics, Opioid', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009771', 'descriptor_name': 'Obsessive-Compulsive Disorder', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D014147', 'descriptor_name': 'Tramadol', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000701', 'descriptor_name': 'Analgesics, Opioid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009771', 'descriptor_name': 'Obsessive-Compulsive Disorder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010865', 'descriptor_name': 'Pilot Projects', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017367', 'descriptor_name': 'Serotonin Uptake Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D017367', 'descriptor_name': 'Serotonin Uptake Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014147', 'descriptor_name': 'Tramadol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/(sici)1520-6394(1997)6:4<170::aid-da7>3.0.co;2-g', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S192592622', 'display_name': 'Depression and Anxiety', 'issn_l': '1091-4269', 'issn': ['1091-4269', '1520-6394'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9559288', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.67, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166', 'https://openalex.org/W1489783725'], 'abstract_inverted_index': {'Depression': [0], 'and': [1, 416, 420, 432, 439, 458], 'AnxietyVolume': [2], '6,': [3], 'Issue': [4], '4': [5], 'p.': [6], '170-173': [7, 471], 'Brief': [8], 'Report': [9], 'Open-label': [10], 'pilot': [11], 'study': [12], 'of': [13, 36, 39, 42, 46, 49, 52, 82, 85, 88, 109, 112, 115, 136, 139, 142, 163, 166, 169, 190, 193, 196, 222, 225, 228, 232, 235, 238, 268, 271, 274, 295, 298, 301, 322, 325, 328, 349, 352, 355, 376, 379, 382, 418, 428, 441, 452], 'tramadol': [14], 'hydrochloride': [15], 'in': [16], 'treatment-refractory': [17], 'obsessive-compulsive': [18], 'disorder': [19], 'Nathan': [20, 27, 206, 213], 'A.': [21, 28, 207, 214], 'Shapira': [22, 29, 208, 215], 'MD,': [23, 30, 209, 216], 'Ph.D.,': [24, 154, 210, 340], 'Corresponding': [25, 211], 'Author': [26, 212], 'Ph.D.': [31, 158, 217, 344], 'Biological': [32, 78, 105, 132, 159, 186, 218, 264, 291, 318, 345, 372], 'Psychiatry': [33, 79, 106, 133, 160, 187, 219, 265, 292, 319, 346, 373], 'Program,': [34, 80, 107, 134, 161, 188, 220, 266, 293, 320, 347, 374], 'Department': [35, 51, 81, 108, 135, 162, 189, 221, 237, 267, 294, 321, 348, 375], 'Psychiatry,': [37, 53, 83, 110, 137, 164, 191, 223, 239, 269, 296, 323, 350, 377], 'University': [38, 84, 111, 138, 165, 192, 224, 270, 297, 324, 351, 378], 'Cincinnati': [40, 47, 86, 113, 140, 167, 194, 226, 233, 272, 299, 326, 353, 380], 'College': [41, 48, 87, 114, 141, 168, 195, 227, 234, 273, 300, 327, 354, 381], 'Medicine,': [43, 50, 89, 116, 143, 170, 197, 229, 236, 275, 302, 329, 356, 383], 'Cincinnati,': [44, 60, 90, 117, 144, 171, 198, 230, 246, 276, 303, 330, 357, 384], 'OhioUniversity': [45, 231], 'P.O.': [54, 240], 'Box': [55, 241], '670559,': [56, 242], '231': [57, 243], 'Bethesda': [58, 244], 'Avenue,': [59, 245], 'OH': [61, 247], '45267-0559.Search': [62, 248], 'for': [63, 92, 119, 146, 173, 200, 249, 278, 305, 332, 359, 386], 'more': [64, 93, 120, 147, 174, 201, 250, 279, 306, 333, 360, 387], 'papers': [65, 94, 121, 148, 175, 202, 251, 280, 307, 334, 361, 388], 'by': [66, 95, 122, 149, 176, 203, 252, 281, 308, 335, 362, 389], 'this': [67, 96, 123, 150, 177, 204, 253, 282, 309, 336, 363, 390, 453], 'authorPaul': [68, 254], 'E.': [69, 74, 255, 260], 'Keck': [70, 75, 256, 261], 'Jr.': [71, 76, 257, 262], 'M.D.,': [72, 100, 127, 153, 157, 181, 258, 286, 313, 339, 343, 367], 'Paul': [73, 259], 'M.D.': [77, 104, 131, 185, 263, 290, 317, 371], 'OhioSearch': [91, 118, 145, 172, 199, 277, 304, 331, 358, 385], 'authorToby': [97, 283], 'D.': [98, 102, 284, 288], 'Goldsmith': [99, 103, 285, 289], 'Toby': [101, 287], 'authorBrian': [124, 310], 'J.': [125, 129, 311, 315], 'McConville': [126, 130, 312, 316], 'Brian': [128, 314], 'authorMichael': [151, 337], 'Eis': [152, 156, 338, 342], 'Michael': [155, 341], 'authorSusan': [178, 364], 'L.': [179, 183, 365, 369], 'McElroy': [180, 184, 366, 370], 'Susan': [182, 368], 'author': [205, 391], 'First': [392], 'published:': [393], '07': [394], 'December': [395], '1998': [396], 'https://doi.org/10.1002/(SICI)1520-6394(1997)6:4<170::AID-DA7>3.0.CO;2-GCitations:': [397], '50AboutPDF': [398], 'ToolsRequest': [399], 'permissionExport': [400], 'citationAdd': [401], 'to': [402, 424, 447], 'favoritesTrack': [403], 'citation': [404], 'ShareShare': [405], 'Give': [406], 'accessShare': [407, 410], 'full': [408], 'text': [409], 'full-text': [411, 426, 450], 'accessPlease': [412], 'review': [413], 'our': [414], 'Terms': [415, 438], 'Conditions': [417, 440], 'Use': [419], 'check': [421], 'box': [422], 'below': [423, 446], 'share': [425, 448], 'version': [427, 451], 'article.I': [429], 'have': [430], 'read': [431], 'accept': [433], 'the': [434, 444], 'Wiley': [435], 'Online': [436], 'Library': [437], 'UseShareable': [442], 'LinkUse': [443], 'link': [445], 'a': [449, 464], 'article': [454], 'with': [455], 'your': [456], 'friends': [457], 'colleagues.': [459], 'Learn': [460], 'more.Copy': [461], 'URL': [462], 'Share': [463], 'linkShare': [465], 'onFacebookTwitterLinkedInRedditWechat': [466], 'Citing': [467], 'Literature': [468], 'Volume6,': [469], 'Issue41997Pages': [470], 'RelatedInformation': [472]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1983972036', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-21T16:46:38.143319', 'created_date': '2016-06-24'}