Publication Information

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4200], 'highly': [79], 'conserved': [80], 'growth': [81], 'factors': [82, 544, 1479, 1742], 'that': [83, 199, 307, 352, 599, 648, 669, 822, 948, 991, 1210, 1414, 1743, 1869, 1932, 2010, 2041, 2226, 2455, 2571, 2646, 2662, 2726, 2744, 2936, 2949, 3066, 3195, 3274, 3304, 3356, 3461, 3524, 3619, 3640, 3738, 3814, 3837, 3849, 3883, 4014, 4101, 4182], 'responsible': [85, 3631], 'for': [86, 428, 588, 662, 676, 1038, 1752, 2344, 2383, 2441, 2491, 2495, 2876, 3416, 3470, 3590, 3632, 3645, 3652, 3724, 3806, 3965], 'important': [87, 310, 4012, 4129], 'homeostatic': [90], 'processes': [91, 251, 3035], 'throughout': [92], 'animal': [94], 'kingdom': [95], '(for': [96], 'more': [98, 1259, 2629, 3046, 3538, 3733, 3961, 4122, 4132, 4193], 'comprehensive': [99], 'review': [100, 3126], 'see': [101, 4154], 'Ref.': [102, 254, 2417, 3856, 3895], '1Logan': [103], 'C.Y.': [104], 'Nusse': [105, 634, 1101, 2470, 3074, 3501, 3563, 3945], 'R.': [106, 635, 686, 769, 1102, 1349, 1510, 1712, 1779, 1901, 1945, 2053, 2055, 2156, 2194, 2196, 2269, 2271, 2471, 2523, 2682, 3075, 3254, 3502, 3564, 3946], 'Annu.': [107], 'Rev.': [108, 3906], 'Cell': [109, 1197, 1726, 1785, 1907, 1951, 2029, 2583], 'Dev.': [110, 261, 930, 1616, 2711, 3607], 'Biol.': [111, 1198, 1662, 1727, 1786, 1908, 1952, 2030, 2059, 2103, 2584, 3077, 3239], '2004;': [112, 871, 1435, 2031, 2585, 3908], '20:': [113], '781-810Crossref': [114], 'PubMed': [115, 271, 463, 574, 640, 701, 728, 784, 874, 894, 940, 1109, 1142, 1202, 1312, 1360, 1385, 1438, 1500, 1544, 1602, 1620, 1666, 1718, 1731, 1790, 1822, 1837, 1855, 1912, 1956, 1988, 2003, 2034, 2068, 2107, 2172, 2212, 2287, 2375, 2424, 2476, 2534, 2547, 2588, 2693, 2715, 2803, 2827, 2848, 2922, 2972, 3025, 3081, 3248, 3265, 3349, 3407, 3507, 3569, 3611, 3684, 3706, 3865, 3911, 3951], 'Scopus': [116, 272, 464, 575, 641, 702, 729, 785, 875, 895, 941, 1110, 1143, 1203, 1313, 1361, 1386, 1439, 1501, 1545, 1603, 1621, 1667, 1732, 1791, 1823, 1856, 1913, 1957, 1989, 2035, 2069, 2108, 2173, 2213, 2288, 2376, 2425, 2535, 2589, 2694, 2716, 2804, 2828, 2849, 2973, 3026, 3082, 3249, 3266, 3350, 3408, 3508, 3570, 3612, 3685, 3707, 3866, 3912, 3952], '(4196)': [117], 'Google': [118, 274, 466, 577, 643, 704, 731, 787, 877, 897, 943, 1112, 1145, 1205, 1315, 1363, 1388, 1441, 1503, 1547, 1605, 1623, 1669, 1719, 1734, 1793, 1825, 1838, 1858, 1915, 1959, 1991, 2004, 2037, 2071, 2110, 2175, 2215, 2290, 2378, 2427, 2477, 2537, 2548, 2591, 2696, 2718, 2806, 2830, 2851, 2923, 2975, 3028, 3084, 3251, 3268, 3352, 3410, 3510, 3572, 3614, 3687, 3709, 3868, 3914, 3954], 'Scholar).': [119, 275, 467, 578, 644, 732, 788, 898, 944, 1146, 1206, 1316, 1389, 1442, 1548, 1624, 1670, 1735, 1859, 1916, 2072, 2216, 2291, 2379, 2428, 2478, 2549, 2592, 2719, 2852, 2924, 2976, 3029, 3085, 3269, 3353, 3411, 3511, 3573, 3615, 3710, 3869, 3915, 3955], 'Their': [120], 'implication': [121], 'wide': [124, 3886], 'array': [125], 'events': [128, 990, 1044], 'human': [130, 3827], 'diseases': [131, 3828, 3882], 'has': [132, 150, 170, 224, 735, 759, 977, 983, 1035, 2042, 2452, 3199, 3479, 3657, 3958], 'made': [133, 3959], 'their': [136], 'subject': [140], 'intense': [142, 3783], 'investigation': [143], 'over': [144, 1039, 3430, 3770], 'last': [146, 3308], 'two': [147, 847], 'decades.': [148], 'This': [149, 2739, 3354, 3574, 3956], 'never': [151], 'been': [152, 202, 736, 760, 980, 984, 1036, 2044, 2500, 2991, 3659, 3879], 'truer': [153], 'than': [154, 190, 2735, 3540, 3962], 'past': [157, 3778], 'few': [158], 'years,': [159], 'when': [160, 845], 'association': [162, 1074, 2866], 'Wnt': [164, 181, 230, 325, 469, 604, 611, 677, 739, 749, 793, 817, 964, 974, 1033, 1059, 1166, 1277, 1485, 1579, 1652, 2320, 2348, 2434, 2463, 2640, 2766, 2868, 2877, 2890, 3140, 3153, 3178, 3197, 3216, 3361, 3421, 3436, 3462, 3593, 3638, 3747, 3795, 3799, 3817, 3875, 3971, 4002, 4029, 4092, 4119, 4168], 'with': [166, 204, 531, 1471, 1562, 1871, 2121, 3881, 4170], 'stem': [167, 3927, 3991], 'cell': [168, 389, 2316, 2411, 3170, 3928, 4077], 'fate': [169], 'added': [171], 'fuel': [172], 'already': [175, 3480], 'active': [176, 916], 'field.': [177], 'Membership': [178], 'defined': [184], 'by': [185, 350, 419, 430, 507, 1049, 1180, 1265, 1325, 1332, 1936, 2014, 2082, 2115, 2223, 2246, 2322, 2554, 2577, 2775, 3529, 3625, 3726, 4044], 'amino': [186, 3447], 'acid': [187, 3448], 'sequence': [188, 3449, 3545], 'rather': [189, 2351, 2734], 'functional': [191], 'properties.': [192], 'It': [193, 3616], 'therefore': [195, 803], 'not': [196, 978, 1169, 2342, 2741, 2952, 3039, 3278], 'surprising': [198, 3271], 'have': [201, 1065, 2498, 2887, 2990, 3214, 3802, 3878, 4165], 'associated': [203, 3880], 'number': [206, 1739, 2979, 3144, 3787, 3825, 4010, 4173], 'different': [208, 2315, 2324], 'downstream': [211, 2610, 2956, 3101], 'pathways.': [213], 'Although': [214, 1029], 'majority': [216], 'work': [218, 3090], 'field': [221], 'date': [223], 'focused': [225], 'on': [226, 283, 297, 1071, 1178, 1329, 2393, 3068, 3768, 4166], 'β-catenin-dependent,': [227], 'canonical,': [229], 'signaling,': [231, 2349, 2497], 'examples': [232, 4175], 'continue': [233], 'accumulate': [235], 'which': [237, 792, 1055, 1690, 2312, 2487, 3584, 3621, 3773, 3842, 4045], 'and/or': [239, 2655, 3722], 'other': [240, 1248, 1741, 2122, 3051, 4083], 'key': [241, 961, 1007, 1215, 1330, 3987], 'components': [242, 2959, 3053, 3148, 3877], 'canonical': [245, 285, 324, 2462, 2957, 3061, 4167], 'cascade': [247, 2089], 'participate': [248], 'β-catenin-independent': [250, 301, 4177], '(reviewed': [252, 2415], '2Veeman': [255], 'M.T.': [256], 'Axelrod': [257], 'J.D.': [258, 3489, 3551, 3933], 'Moon': [259, 1723], 'R.T.': [260, 1585, 1724, 3897], 'Cell.': [262, 454, 565, 931, 1133, 1303, 1535, 1813, 1846, 1979, 2102, 2163, 2203, 2278, 3675, 3697], '2003;': [263, 932, 1106, 1134, 2104, 2421, 2712, 2800, 2969, 3504, 3566, 3948], '5:': [264, 3909], '367-377Abstract': [265], 'Full': [266, 268, 458, 460, 569, 571, 935, 937, 1137, 1139, 1307, 1309, 1539, 1541, 1817, 1819, 1850, 1852, 1983, 1985, 2063, 2065, 2167, 2169, 2207, 2209, 2282, 2284, 3243, 3245, 3260, 3262, 3679, 3681, 3701, 3703], 'Text': [267, 269, 459, 461, 570, 572, 936, 938, 1138, 1140, 1308, 1310, 1540, 1542, 1818, 1820, 1851, 1853, 1984, 1986, 2064, 2066, 2168, 2170, 2208, 2210, 2283, 2285, 3244, 3246, 3261, 3263, 3680, 3682, 3702, 3704], 'PDF': [270, 462, 573, 939, 1141, 1311, 1543, 1821, 1854, 1987, 2067, 2171, 2211, 2286, 3247, 3264, 3683, 3705], '(1150)': [273], 'this': [277, 1010, 1444, 1674, 2442, 2669, 3129, 3476, 3641, 4096, 4197], 'review,': [278], 'we': [279, 4156, 4164], 'will': [280, 294, 3044, 4127, 4150, 4204], 'focus': [281], 'largely': [282], 'pathway,': [286], 'paying': [287], 'particular': [288, 3169], 'attention': [289], 'recent': [291, 3193, 3283, 3459], 'insights.': [292], 'We': [293], 'then': [295, 3720], 'touch': [296], 'some': [298, 305, 3471], 'developments': [299], 'discuss': [304], 'issues': [306], 'may': [308, 1691, 2079, 2301, 2871, 3189, 3627, 3739], 'be': [309, 2080, 3093, 3223, 3465, 3515, 3588, 3628, 3740, 4037, 4128, 4151], 'all': [312, 4189], 'Wnts,': [313, 2981], 'regardless': [314], 'they': [318], 'generate.': [319], 'defining': [321, 3096], 'event': [322, 962], 'cytoplasmic': [329, 412, 957, 1226, 1270, 2017], 'accumulation': [330], 'β-catenin': [332, 346, 415, 422, 505, 512, 1003, 1227, 1403, 1469, 1626, 1872, 1884, 2018, 2116, 2298, 2496, 2605, 3119, 4047, 4068], 'its': [334, 971, 1635, 2333, 2345, 2352, 2457, 3424, 4070], 'subsequent': [335, 2007], 'nuclear': [336, 1559, 1930, 2299, 4065], 'translocation': [337], '(Fig.': [340, 509, 2878], '1).': [341], 'Under': [342], 'unstimulated': [343], 'conditions,': [344], 'destruction': [347, 1004, 1228, 4048], 'complex': [348, 474, 497, 745, 1064, 1229, 1235, 1461, 1574, 1642, 1676, 1685, 1748, 1773, 1895, 1939, 2229, 4049, 4199], 'formed': [349], 'proteins': [351, 658, 678, 1868, 3463, 3972, 4104, 4139, 4203], 'include': [353], 'Axin,': [354], 'adenomatous': [355, 364, 3845], 'polyposis': [356, 365], 'coli': [357], '(APC),': [358], '2The': [359], 'abbreviations': [360], 'used': [361], 'are:': [362], 'APC,': [363, 3839], 'coli;': [366], 'GSK,': [367], 'glycogen': [368, 406], 'synthase': [369, 407], 'kinase;': [370, 397], 'LRP,': [371, 741, 837], 'low': [372, 416, 489], 'density': [373, 490], 'lipoprotein': [374, 491], 'receptor-related': [375, 492], 'protein;': [376, 400], 'TCF,': [377], 'T': [378, 533], 'cell-specific': [379, 534], 'transcription': [380, 535, 543, 1478, 1483, 1577, 1650, 2013, 2237], 'factor;': [381], 'LEF,': [382], 'lymphoid': [383], 'enhancer-binding': [384, 537], 'factor': [385, 538, 1770, 3822], '1;': [386], 'PCP,': [387, 2627], 'planar': [388, 2410], 'polarity;': [390], 'CE,': [391, 2733], 'convergence': [392, 2507], 'extension;': [393], 'RTK,': [394, 3070], 'receptor': [395, 473, 587, 917, 1220, 2786, 2935], 'tyrosine': [396, 2787], 'CBP,': [398], 'CREB-binding': [399], 'CREB,': [401], 'cAMP-response': [402], 'element-binding': [403], 'protein.': [404], 'kinase': [408, 2088, 2788], '3β': [409], '(GSK-3)': [410], 'keeps': [411], 'levels': [413], 'through': [417, 529, 1446, 1693, 2119, 2779, 2995, 3219], 'phosphorylation': [418, 506, 1081, 1181, 1326], 'GSK-3.': [420], 'Phosphorylated': [421], 'becomes': [423], 'ubiquitylated': [424], 'targeted': [427, 3723], 'degradation': [429], 'proteasome': [432], '(3Zeng': [433], 'L.': [434, 713, 867, 1299, 1493, 2519, 2678], 'Fagotto': [435], 'F.': [436, 453, 692, 775, 865, 1710, 1777, 1899, 1943, 2705], 'Zhang': [437, 2185, 2260], 'T.': [438, 1526, 1796, 1962, 2096, 2140, 3497, 3559, 3597, 3941], 'Hsu': [439], 'W.': [440, 1085, 1286, 1368, 2190, 2265], 'Vasicek': [441], 'T.J.': [442], 'Perry': [443], '3rd,': [444, 1288, 3499, 3561, 3943], 'W.L.': [445], 'Lee': [446, 1120], 'J.J.': [447, 1187], 'Tilghman': [448], 'S.M.': [449], 'Gumbiner': [450], 'B.M.': [451], 'Costantini': [452], '1997;': [455, 1497, 1536], '90:': [456], '181-192Abstract': [457], '(785)': [465], 'Following': [468], 'binding': [470, 734, 1266, 1552, 1636, 1700, 2247, 2891, 4030], 'composed': [475, 2090], 'members': [477, 649, 1249, 1472, 1672, 2882], 'Frizzled': [480, 1050], '(Fz)': [481], 'seven': [484], 'transmembrane,': [485], 'serpentine': [486], 'receptors': [487, 998], 'protein': [493, 1245, 2087, 2767, 3052, 3582], '(LRP),': [494], 'Axin·APC·GSK-3': [496, 1021, 1453], 'inhibited,': [499], 'leading': [500, 1045], 'block': [503, 1576, 3060], 'GSK-3': [508, 1337], '1B).': [510], 'Hypophosphorylated': [511], 'accumulates': [513], 'cytoplasm': [516], 'translocated': [519], 'nucleus': [522, 2021], 'where': [523], 'it': [524, 823, 1630, 2632, 3131, 3521, 4126, 4149], 'regulates': [525], 'target': [526, 1486, 1580, 1653, 2330, 4073, 4102], 'gene': [527, 2339, 2451, 2641, 3198, 3650], 'expression': [528], 'partnerships': [530], 'factor/lymphoid': [536], '1': [539, 1771], '(TCF/LEF)': [540], '(4Molenaar': [545], 'M.': [546, 550, 552, 621, 682, 707, 765, 921, 1127, 1508, 1515, 1530, 1532, 1595, 1783, 1808, 1905, 1949, 1974, 2027, 2515, 2540, 2674, 2707, 2796, 2965, 3237, 3329, 3387, 3696], 'van': [547, 1513, 1516, 1708], 'de': [548, 1506], 'Wetering': [549, 1507], 'Oosterwegel': [551], 'Peterson-Maduro': [553], 'J.': [554, 560, 633, 1090, 1131, 1280, 1282, 1353, 1370, 1372, 1518, 1520, 1589, 1610, 1714, 1725, 1830, 1996, 2098, 2148, 2180, 2186, 2255, 2261, 2811, 2835, 3009, 3331, 3389, 3601, 3859], 'Godsave': [555], 'S.': [556, 715, 723, 927, 1092, 1295, 1345, 1612, 1806, 1810, 1972, 1976, 2368, 2792, 2961], 'Korinek': [557], 'V.': [558, 2150], 'Roose': [559, 1588], 'Destree': [561], 'O.': [562, 1491, 1798, 1964], 'Clevers': [563, 1533, 1592], 'H.': [564, 869, 1293, 1347, 1351, 1534, 1593, 1781, 1903, 1947, 2701], '1996;': [566, 637, 3608], '86:': [567], '391-399Abstract': [568], '(1608)': [576], 'role': [580, 1160, 1216, 1261, 2346], 'Fz': [582, 593, 609, 670, 754, 799, 835, 863, 912, 954, 1076, 1410, 2625, 2863, 4032], 'acting': [584], 'long': [591, 2617, 3438], 'established;': [592], 'carries': [594], 'extracellular': [596, 757, 2889], 'cysteine-rich': [597, 2893], 'domain': [598, 1400, 2908], 'sufficient': [601, 809, 840, 1420], 'bind': [603, 1744], 'proteins,': [605, 2124], 'addition': [607, 900, 2430, 3633], 'nonresponsive': [612], 'cells': [613, 3595, 3980], 'render': [615], 'competence': [617], '(5Bhanot': [618], 'P.': [619, 1376, 2132, 2152, 3670], 'Brink': [620], 'Samos': [622], 'C.H.': [623], 'Hsieh': [624], 'J.C.': [625, 2527, 2542, 2686], 'Wang': [626, 1281, 2147, 2814, 3012], 'Y.': [627, 684, 690, 767, 773, 1123, 2809, 2821, 2843, 3007, 3019], 'Macke': [628], 'J.P.': [629, 694, 777], 'Andrew': [630], 'D.': [631, 717, 1088, 1125, 1297, 1301, 1512, 1524, 1802, 1968, 2198, 2273, 2419, 3666, 3694], 'Nathans': [632], 'Nature.': [636, 697, 724, 780, 1356, 1381, 1496, 1598, 2371, 2530, 2689, 2799, 2844, 2968, 3345, 3403, 3503, 3565, 3947], '382:': [638], '225-230Crossref': [639], '(1219)': [642], 'However,': [645, 1917, 2613, 2720, 3870], 'discovery': [647, 3194, 3460], 'LRP': [652, 672, 756, 801, 906, 956, 1273, 1322, 1328, 1398, 4034], 'single': [655], 'pass': [656], 'transmembrane': [657], 'also': [660, 2239, 2439, 2499, 2552], 'immediately': [665], 'raised': [666, 3481], 'possibility': [668], 'function': [673, 1920, 2244, 2353, 2458, 2557, 2875], 'co-receptors': [675], '(6Tamai': [679, 762], 'K.': [680, 711, 763, 1341, 1425, 1495, 1705, 1812, 1845, 1978, 2057, 2100, 3325, 3383, 3487, 3549, 3603, 3674, 3690, 3931], 'Semenov': [681, 764], 'Kato': [683, 766], 'Spokony': [685, 768], 'Liu': [687, 770, 1283], 'C.': [688, 771, 1189, 1291, 1380, 1841, 2130, 2144, 2182, 2257, 3327, 3385, 3664, 3668], 'Katsuyama': [689, 772], 'Hess': [691, 774], 'Saint-Jeannet': [693, 776], 'He': [695, 778, 1354], 'X.': [696, 779, 1339, 1355, 2200, 2275], '2000;': [698, 725, 781, 1715, 1728, 2531, 2544, 2690], '407:': [699, 726, 782], '530-535Crossref': [700, 783], '(1081)': [703, 786], 'Scholar,': [705, 878, 1113, 1364, 1504, 1606, 1720, 1794, 1826, 1839, 1960, 1992, 2176, 2538, 2697, 2807, 2831, 3252, 3688], '7Wehrli': [706], 'Dougan': [708], 'S.T.': [709], 'Caldwell': [710], "O'Keefe": [712], 'Schwartz': [714], 'Vaizel-Ohayon': [716], 'Schejter': [718], 'E.': [719, 929, 1489, 1800, 1966, 3491, 3553, 3599, 3935], 'Tomlinson': [720], 'A.': [721, 923, 1117, 1119, 1378, 1522, 1528, 1597, 1703, 2025, 2146, 2160, 2184, 2259, 2467, 2469, 3235, 3323, 3338, 3381, 3396, 3904], 'DiNardo': [722, 926], '527-530Crossref': [727], '(717)': [730], 'Indeed,': [733], 'seen': [737, 3164], 'between': [738, 746, 798, 1075], 'ternary': [744], 'mouse': [748, 3034], 'soluble': [751, 3517], 'forms': [752], 'domains': [758, 958, 2894], 'reported': [761], 'A': [789, 1006, 1207], 'model': [790, 2051], 'physically': [794], 'mediates': [795, 2937], 'interaction': [797, 808, 3113], 'appealing.': [804], 'Is': [805], 'induce': [811, 842, 1402], 'absence': [815, 1408, 1557], 'binding?': [818], 'Early': [819], 'reports': [820], 'suggest': [821], 'is.': [824], 'Fusion': [825], 'heterologous': [828], 'ligand/receptor': [829], 'pair': [830, 1866], '(NT3': [831], 'TrkN)': [833], 'respectively,': [838], 'Wnt-independent': [843, 2862], 'molecules': [848, 4100], 'co-overexpressed,': [850], 'fusion': [854], 'natural': [857], 'LRP-binding': [858], 'protein,': [859], 'Dickkopf': [860], '(DKK),': [861], '(8Cong': [864], 'Schweizer': [866, 1492], 'Varmus': [868], 'Development.': [870, 1833, 1999, 2420, 2543], '131:': [872], '5103-5115Crossref': [873], '(272)': [876], '9Holmen': [879], 'S.L.': [880], 'Robertson': [881], 'S.A.': [882, 2917], 'Zylstra': [883], 'C.R.': [884, 2366], 'Williams': [885, 1194], 'B.O.': [886], 'Biochem.': [887], 'Biophys.': [888], 'Res.': [889], 'Commun.': [890], '2005;': [891, 1357, 1382, 1663, 2060, 2824, 3022, 3346, 3404], '328:': [892], '533-539Crossref': [893], '(40)': [896], 'Lastly,': [899, 3916], 'intracellular': [903, 1399], 'portion': [904], 'C': [909], 'terminus': [910, 1882], 'creates': [913], 'constitutively': [915], '(10Tolwinski': [918], 'N.S.': [919, 2138], 'Wehrli': [920], 'Rives': [922], 'Erdeniz': [924], 'N.': [925, 3231, 3605, 3692], 'Wieschaus': [928], '4:': [933, 1788, 1910, 1954, 3079], '407-418Abstract': [934], '(251)': [942], 'These': [945], 'data': [946], 'argue': [947], 'inducing': [949], 'proximity': [951], 'initiation,': [966], 'although': [967, 1157], 'direct': [968, 2724], 'evidence': [969, 2594, 2725, 3813], 'occurrence': [972], 'upon': [973, 4028, 4091], 'ligand': [975], 'reception': [976, 1278], 'yet': [979], 'reported.': [981], 'There': [982, 1736, 2636], 'interest': [986, 3784, 4116], 'elucidating': [988], 'bridge': [992], 'activation': [994, 1048, 1221, 1264, 1935], 'Fz/LRP': [997], 'inhibition': [1000, 1022, 1223], 'complex.': [1005], 'intermediate': [1008], 'process': [1011, 2505, 2948, 3065], 'Dishevelled': [1013], '(Dsh),': [1014], 'cytosolic': [1016], 'phosphoprotein': [1017], 'upstream': [1019, 2623], 'both': [1024, 1688, 2232], 'fly': [1025, 2449, 2645, 3032], 'mammalian': [1027, 2985, 3001], "Dishevelled's": [1030], 'requirement': [1031], 'known': [1037, 2407, 2639, 3513, 3586], 'decade,': [1041], 'molecular': [1043, 3712], 'Dsh': [1047, 1056, 1078, 1083, 1179, 2483, 2954], 'manner': [1053], 'transduces': [1057], 'inhibitory': [1063, 2906], 'remained': [1066], 'murky.': [1067], 'Several': [1068], 'papers': [1069], 'report': [1070, 2008], 'physical': [1073], 'Wnt-dependent': [1080], '(11Chen': [1084], 'ten': [1086], 'Berge': [1087], 'Brown': [1089, 1432, 3488, 3550, 3932], 'Ahn': [1091], 'Hu': [1093], 'L.A.': [1094, 1429, 2841], 'Miller': [1095], 'W.E.': [1096], 'Caron': [1097], 'M.G.': [1098, 2162, 2202, 2277], 'Barak': [1099], 'L.S.': [1100], 'Lefkowitz': [1103], 'R.J.': [1104], 'Science.': [1105], '301:': [1107], '1391-1394Crossref': [1108], '(291)': [1111], '12Wong': [1114], 'H.C.': [1115], 'Bourdelas': [1116], 'Krauss': [1118], 'H.J.': [1121], 'Shao': [1122], 'Wu': [1124, 1300, 1367, 2189, 2264], 'Mlodzik': [1126], 'Shi': [1128, 2810, 2834, 3008], 'D.L.': [1129, 1656, 2525, 2684], 'Zheng': [1130], 'Mol.': [1132, 1302, 1661, 2101], '12:': [1135, 1664, 3241], '1251-1260Abstract': [1136], '(391)': [1144], 'kinases': [1148, 1334], 'PAR-1': [1149], 'CKII': [1151], 'appear': [1152, 3918], 'directly': [1154, 1218, 1267, 1631, 1878], 'phosphorylate': [1155, 1463], 'Dsh,': [1156, 1412, 2437], 'precise': [1159], 'each': [1162, 3111, 3196, 4145], 'transducing': [1164, 2776], 'entirely': [1170], 'clear': [1171], 'nor': [1172], 'specific': [1175, 4111], 'bestowed': [1177], '(13Sun': [1182], 'T.Q.': [1183], 'Lu': [1184, 2812, 2838, 3010], 'B.': [1185, 1284, 1343, 1775, 1804, 1897, 1941, 1970, 2699, 3229, 3340, 3398], 'Feng': [1186], 'Reinhard': [1188], 'Jan': [1190], 'Y.N.': [1191], 'Fantl': [1192], 'W.J.': [1193], 'L.T.': [1195], 'Nat.': [1196, 1659, 1784, 1906, 1950, 2028, 2582, 2822, 3020, 3905], '2001;': [1199, 1304, 2919, 3257], '3:': [1200], '628-636Crossref': [1201], '(208)': [1204], 'second': [1208, 3649], 'component': [1209], 'appears': [1211, 1255], 'play': [1213, 1257], 'linking': [1219, 1246], 'member': [1232, 1686, 1766, 2783], 'itself,': [1236], 'Axin.': [1237], 'Once': [1238, 1465], 'thought': [1239, 1926, 3618], 'simply': [1242, 2736], 'scaffold': [1244], 'together': [1247], 'complex,': [1252, 1454], 'Axin': [1253, 1320, 1418, 1449], 'now': [1254, 2406], 'dynamic': [1260], 'tail': [1271], 'response': [1275], '(14Mao': [1279], 'Pan': [1285], 'Farr': [1287], 'G.H.': [1289], 'Flynn': [1290], 'Yuan': [1292], 'Takada': [1294], 'Kimelman': [1296], 'Li': [1298, 1344, 2199, 2274], '7:': [1305], '801-809Abstract': [1306], '(686)': [1314], 'recruitment': [1318, 1416], 'mediated': [1324, 2245], 'residues': [1331], 'CK1γ': [1335], '(15Zeng': [1338], 'Tamai': [1340], 'Doble': [1342], 'Huang': [1346], 'Habas': [1348], 'Okamura': [1350], 'Woodgett': [1352], '438:': [1358, 1383], '873-877Crossref': [1359], '(649)': [1362], '16Davidson': [1365], 'G.': [1366, 1608, 1843, 3233, 3672], 'Shen': [1369], 'Bilic': [1371], 'Fenger': [1373], 'U.': [1374, 3335, 3393], 'Stannek': [1375], 'Glinka': [1377], 'Niehrs': [1379], '867-872Crossref': [1384], '(462)': [1387], 'Surprisingly,': [1390], 'overexpression': [1391], 'membrane-tethered': [1394], 'form': [1395, 1571], 'accumulation,': [1404], 'even': [1405, 3123], 'suggesting': [1413, 2570, 2661], 'membrane': [1415], 'activate': [1422, 1481], '(17Brennan': [1424], 'Gonzalez-Sancho': [1426], 'J.M.': [1427], 'Castelo-Soccio': [1428], 'Howe': [1430], 'L.R.': [1431], 'A.M.': [1433, 2833, 2837], 'Oncogene.': [1434], '23:': [1436, 2105, 2920], '4873-4884Crossref': [1437], '(90)': [1440], 'Presumably': [1443], 'occurs': [1445], 'titration': [1447], 'away': [1450], 'thereby': [1455, 1647], 'compromising': [1456], 'ability': [1458], 'β-catenin.': [1464], 'nucleus,': [1468, 1629], 'partners': [1470, 1561], 'LEF/TCF': [1475], 'genes': [1487, 1581, 1654, 2565, 2657, 3217, 4089], '(18Brunner': [1488], 'Peter': [1490, 1797, 1963], 'Basler': [1494, 1811, 1844, 1977, 2056, 3673], '385:': [1498], '829-833Crossref': [1499], '(444)': [1502], '19van': [1505], 'Cavallo': [1509], 'Dooijes': [1511], 'Beest': [1514], 'Es': [1517], 'Loureiro': [1519], 'Ypma': [1521], 'Hursh': [1523], 'Jones': [1525], 'Bejsovec': [1527, 1596], 'Peifer': [1529, 1594], 'Mortin': [1531], '88:': [1537], '789-799Abstract': [1538], '(1058)': [1546], 'TCF': [1549, 1638, 1699, 2077], 'provides': [1550], 'sequence-specific': [1551], 'and,': [1554], 'β-catenin,': [1560], 'transcriptional': [1564, 1645, 1753, 1934], 'repressor': [1565], 'Groucho': [1566, 1633, 2251], 'histone': [1568, 1679], 'deacetylases': [1569], 'repressive': [1573], '(20Cavallo': [1582], 'R.A.': [1583], 'Cox': [1584], 'Moline': [1586], 'M.M.': [1587, 2192, 2267, 2915], 'Polevoy': [1590], 'G.A.': [1591], '1998;': [1599], '395:': [1600], '604-608Crossref': [1601], '(594)': [1604], '21Chen': [1607], 'Fernandez': [1609], 'Mische': [1611], 'Courey': [1613], 'A.J.': [1614, 3073], 'Genes': [1615, 3606], '1999;': [1617], '13:': [1618], '2218-2230Crossref': [1619], '(353)': [1622], 'When': [1625], 'enters': [1627], 'replaces': [1632], 'converts': [1640], 'activator,': [1646], 'effecting': [1648], '(22Daniels': [1655], 'Weis': [1657], 'W.I.': [1658], 'Struct.': [1660], '364-371Crossref': [1665], '(424)': [1668], 'Other': [1671], 'activating': [1675], 'acetylase': [1680], 'CBP/p300': [1681], 'SWI/SNF': [1684], 'Brg-1,': [1687], 'act': [1692, 2231, 2665, 2728, 2747, 2994], 'remodeling': [1695], 'chromatin': [1697], 'surrounding': [1698], 'sites': [1701], '(23Hecht': [1702], 'Vleminckx': [1704], 'Stemmler': [1706], 'M.P.': [1707], 'Roy': [1709], 'Kemler': [1711, 2155, 2193, 2268], 'EMBO': [1713], '19:': [1716], '1839-1850Crossref': [1717], '24Takemaru': [1721], 'K.I.': [1722], '149:': [1729], '249-254Crossref': [1730], '(402)': [1733], 'TCF·β-catenin': [1747, 1938], 'necessary': [1751], 'activation,': [1754], 'including': [1755, 2125, 2982], 'Legless': [1756], '(Lgs),': [1757], 'Pygopus': [1758], '(Pygo),': [1759], 'most': [1761, 2857, 3833], 'recently': [1762, 3658], 'discovered': [1763, 2343, 3523, 3660], 'hyrax/parafibromin,': [1764], 'polymerase-associated': [1769], '(PAF1)': [1772], '(25Thompson': [1774, 1896, 1940], 'Townsley': [1776, 1898, 1942], 'Rosin-Arbesfeld': [1778, 1900, 1944], 'Musisi': [1780, 1902, 1946], 'Bienz': [1782, 1904, 1948, 2026], '2002;': [1787, 1814, 1834, 1909, 1953, 1980, 2000, 2164, 2473, 3240], '367-373Crossref': [1789, 1911, 1955], '(244)': [1792, 1914, 1958], '26Kramps': [1795, 1961], 'Brunner': [1799, 1965], 'Nellen': [1801, 1967], 'Froesch': [1803, 1969], 'Chatterjee': [1805, 1971], 'Murone': [1807, 1973], 'Zullig': [1809, 1975], '109:': [1815, 1981], '47-60Abstract': [1816, 1982], '(496)': [1824, 1990], '27Parker': [1827, 1993], 'D.S.': [1828, 1994], 'Jemison': [1829, 1995], 'Cadigan': [1831, 1997], 'K.M.': [1832, 1998], '129:': [1835, 2001], '2565-2576Crossref': [1836, 2002], '28Mosimann': [1840], 'Hausmann': [1842, 3671], '2006;': [1847, 2204, 2279, 2845, 3078, 3676, 3698, 3862], '125:': [1848, 2205, 2280, 3677, 3699], '327-341Abstract': [1849], '(265)': [1857], 'Lgs': [1860, 1876], 'Pygo': [1862, 1892, 1922, 2011], 'intriguing': [1865], 'associate': [1870], 'nucleus.': [1875], 'binds': [1877], 'N': [1881], 'serves': [1886], 'adaptor': [1889], 'attach': [1891], 'essential': [1919], 'controversial;': [1924], 'initially': [1925], 'cofactor': [1931], 'enhances': [1933], 'Scholar),': [2005, 2038, 2111], 'suggested': [2009], 'affects': [2012], 'recruiting': [2015], 'otherwise': [2016], '(29Townsley': [2022], 'F.M.': [2023], 'Cliffe': [2024], '6:': [2032, 2586], '626-633Crossref': [2033], '(180)': [2036], 'claim': [2040], 'since': [2043], 'refuted': [2045], 'favor': [2047], 'original': [2050], '(30Hoffmans': [2052], 'Stadeli': [2054], 'Curr.': [2058, 3238], '15:': [2061], '1207-1211Abstract': [2062], '(100)': [2070], 'Additionally,': [2073, 4114], 'itself': [2078], 'modulated': [2081], 'mitogen-activated': [2086], 'TAK1': [2092], 'NLK/Nemo': [2094], '(31Ishitani': [2095], 'Ninomiya-Tsuji': [2097], 'Matsumoto': [2099], '1379-1389Crossref': [2106], '(183)': [2109], 'TCF/LEF-independent': [2113], 'occur': [2118], 'interactions': [2120], 'DNA-binding': [2123], 'Pitx2': [2126], 'Prop1': [2128], '(32Kioussi': [2129], 'Briata': [2131], 'Baek': [2133], 'S.H.': [2134], 'Rose': [2135, 2197, 2272], 'D.W.': [2136], 'Hamblet': [2137], 'Herman': [2139], 'Ohgi': [2141, 2187, 2262], 'K.A.': [2142, 2188, 2263], 'Lin': [2143], 'Gleiberman': [2145], 'Brault': [2149], 'Ruiz-Lozano': [2151], 'Nguyen': [2153], 'H.D.': [2154], 'Glass': [2157], 'C.K.': [2158], 'Wynshaw-Boris': [2159], 'Rosenfeld': [2161, 2201, 2276], '111:': [2165], '673-685Abstract': [2166], '(473)': [2174], '33Olson': [2177], 'L.E.': [2178, 2253], 'Tollkuhn': [2179, 2254], 'Scafoglio': [2181, 2256], 'Krones': [2183, 2258], 'Taketo': [2191, 2266], 'Grosschedl': [2195, 2270], '593-605Abstract': [2206, 2281], '(229)': [2214, 2289], 'latter': [2218], 'case': [2219, 2897, 2911], 'further': [2221], 'complicated': [2222], 'observation': [2225, 3272, 3575, 3957], 'Prop1·β-catenin': [2228], 'activator': [2235], 'repressor,': [2242], 'co-repressor': [2250], '(33Olson': [2252], 'all,': [2293], 'emerging': [2295], 'complexity': [2296, 3138], 'speak': [2302], 'one': [2304, 3482], 'fundamental': [2307], 'questions': [2308, 4013], 'field,': [2311], 'how': [2314, 3715, 4024, 4059], 'types': [2317], 'respond': [2318], 'transcribing': [2323], '(although': [2325], 'often': [2326], 'overlapping)': [2327], 'sets': [2328], 'genes.': [2331], 'As': [2332], 'name': [2334], 'denotes,': [2335], 'first': [2337], 'fz': [2338], 'described': [2340], 'was': [2341, 3363, 3413, 3522, 3585], 'but': [2350, 2493, 2649, 3730], 'organizing': [2355], 'bristles': [2357, 2392], 'hairs': [2359, 2390], 'adult': [2362], 'Drosophila': [2363, 2926, 2988], 'cuticle': [2364], '(34Vinson': [2365], 'Conover': [2367], 'Adler': [2369], 'P.N.': [2370], '1989;': [2372], '338:': [2373], '263-264Crossref': [2374], '(302)': [2377], 'flies': [2381, 2596], 'mutant': [2382], 'fz,': [2384], 'normally': [2386], 'uniform': [2387], 'direction': [2388], 'wings': [2395], 'thorax': [2397], 'perturbed,': [2399], 'result': [2401, 3280], 'disrupting': [2403], 'what': [2404, 2621], 'polarity': [2412], '(PCP)': [2413], '35Strutt': [2418], '130:': [2422], '4501-4513Crossref': [2423], '(212)': [2426], 'Fz,': [2432], 'another': [2433, 3069, 3442], 'component,': [2436], 'process,': [2443], 'genetic': [2445], 'analysis': [2446, 3541], 'dsh': [2450], 'revealed': [2453], 'mutations': [2454, 2480, 2642, 2650, 3871], 'separate': [2456], 'PCP': [2460, 2492, 2564, 2574, 2608, 2648, 2855], '(36Penton': [2466], 'Wodarz': [2468], 'Genetics.': [2472], '161:': [2474], '747-762Crossref': [2475], 'Interestingly,': [2479], 'DEP': [2484], '(Dishevelled-Egl20-Pleckstrin)': [2485], 'domain,': [2486, 2892], 'absolutely': [2489], 'dispensable': [2494], 'found': [2501], 'affect': [2503], 'extension': [2508], '(CE)': [2509], 'vertebrates': [2511, 2598], '(37Heisenberg': [2512, 2671], 'C.P.': [2513, 2672, 2709], 'Tada': [2514, 2673, 2706], 'Rauch': [2516, 2675], 'G.J.': [2517, 2676], 'Saude': [2518, 2677], 'Concha': [2520, 2679], 'M.L.': [2521, 2680], 'Geisler': [2522, 2681], 'Stemple': [2524, 2683], 'Smith': [2526, 2541, 2685], 'Wilson': [2528, 2687], 'S.W.': [2529, 2688], '405:': [2532, 2691], '76-81Crossref': [2533, 2692], '(831)': [2536, 2695], '38Tada': [2539], '127:': [2545], '2227-2238Crossref': [2546], 'CE': [2550, 2572, 2659], 'disrupted': [2553], 'loss': [2555], 'vertebrate': [2559, 2756], 'homologs': [2560], 'dedicated': [2563], 'strabismus,': [2566], 'flamingo,': [2567], 'prickle,': [2569], 'controlled': [2576], 'homologous': [2578, 3037], '(39Wallingford': [2580], 'J.B.': [2581, 2798, 2967], '687-689Crossref': [2587], '(11)': [2590], 'All': [2593], 'points': [2599], 'toward': [2600], 'complete': [2602, 4194], 'separation': [2603], 'Dsh.': [2612], 'there': [2614, 2721, 3087, 3451, 4007, 4180], 'outstanding': [2618], 'question': [2619, 4057], 'lies': [2622], 'specifically,': [2630], 'whether': [2631, 4155], 'Wnt.': [2635, 3175], 'no': [2638, 2723], 'disrupt': [2647], 'zebrafish': [2653], 'wnt5': [2654], 'wnt11': [2656], 'phenotypes,': [2660], 'do': [2664], 'ligands': [2667, 4120], 'system': [2670, 2945, 3004], '40Kilian': [2698], 'Mansukoski': [2700], 'Barbosa': [2702], 'F.C.': [2703], 'Ulrich': [2704], 'Heisenberg': [2708], 'Mech.': [2710], '120:': [2713], '467-476Crossref': [2714], '(260)': [2717], 'directional': [2730, 2749, 2770], 'cues': [2731], 'permissive': [2737], 'signals.': [2738, 3056], 'say': [2743], 'cannot': [2746], 'cues;': [2750], 'during': [2751, 2941, 3000], 'development': [2753, 3005, 3366], 'invertebrate': [2758], 'central': [2759, 2943, 3002], 'nervous': [2760, 2944, 3003], 'system,': [2761], 'sources': [2762], 'gradients': [2764], 'guidance': [2771, 2934, 3117], 'extending': [2773], 'axons': [2774], 'Ryk,': [2780, 2929], 'atypical': [2782, 2881], '(RTK)': [2789], '(41Yoshikawa': [2791, 2960], 'McKinnon': [2793, 2962], 'R.D.': [2794, 2963], 'Kokel': [2795, 2964], 'Thomas': [2797, 2966], '422:': [2801, 2970], '583-588Crossref': [2802, 2971], '(341)': [2805, 2974], '42Liu': [2808], 'C.C.': [2813, 2839, 3011], 'Z.B.': [2815, 3013], 'Lyuksyutova': [2816, 3014], 'A.I.': [2817, 3015], 'Song': [2818, 3016], 'X.J.': [2819, 3017], 'Zou': [2820, 2842, 3018], 'Neurosci.': [2823, 3021], '8:': [2825, 3023], '1151-1159Crossref': [2826, 3024], '(224)': [2829, 3027], '43Schmitt': [2832], 'Wolf': [2836], 'King': [2840], '439:': [2846], '31-37Crossref': [2847], '(233)': [2850], 'Just': [2853], 'likely': [2858, 3373], 'example': [2860, 3835], 'function,': [2864], 'RTKs': [2870, 3104], 'illustrate': [2872], 'Fz-independent': [2874], '2).': [2879], 'Certain': [2880], 'RTK': [2885], 'Ror1': [2899], 'Ror2': [2901, 3071], 'WIF': [2904], '(Wnt': [2905], 'factor)': [2907], 'Ryk': [2913, 2996], '(44Halford': [2914], 'Stacker': [2916], 'Bioessays.': [2918], '34-45Crossref': [2921], 'homolog': [2927], 'Derailed,': [2930], 'axon': [2933, 2998, 3116], 'repulsion': [2938], 'Wnt5': [2940], 'embryonic': [2942], 'patterning,': [2946], 'apparently': [2950], 'does': [2951, 4041, 4076], 'involve': [2953], 'Similarly,': [2977, 3647], 'Wnt5a': [2983, 3058], '(a': [2984], 'ortholog': [2986], 'Wnt5),': [2989], 'shown': [2992], 'repellents': [2999], '(42Liu': [3006], 'Whether': [3030], 'known,': [3040], 'answer': [3043, 3188], 'require': [3045], 'detailed': [3047], 'knowledge': [3048], 'mediating': [3054], 'Moreover,': [3057], 'depends': [3067], '(45Mikels': [3072], 'PLoS': [3076], 'e115Crossref': [3080], '(1002)': [3083], 'Clearly,': [3086], 'still': [3091], 'done': [3094], 'Wnt-binding': [3103], 'sorting': [3106], 'out': [3107], 'specificities': [3109], 'ligand/receptor(s)': [3112], 'modulating': [3115], 'stability.': [3120], 'By': [3121], 'reading': [3122], 'cursory': [3125], 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