Publication Information

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251, 323, 1764, 1949, 2103, 2368], 'and': [19, 146, 162, 226, 252, 379, 395, 459, 530, 569, 609, 637, 731, 919, 934, 974, 1129, 1137, 1174, 1658, 1673, 1682, 1709, 1735, 1749, 1807, 1833, 1841, 1856, 1900, 1939, 1948, 1964, 1971, 2002, 2025, 2099, 2143, 2211, 2220, 2321, 2352, 2418, 2446, 2482, 2488, 2530, 2546, 2572, 2578, 2641, 2647, 2718, 2744, 2964, 3050, 3056, 3105, 3126, 3148, 3237, 3283, 3336, 3348, 3364, 3374, 3411, 3431, 3467, 3525, 3663, 3711, 3874, 4087, 4104, 4152, 4258, 4346, 4364], '[Ca2+]i': [20, 253, 1213, 1525, 2361, 2370, 2509, 2515, 2573, 3178, 3214, 3233, 3271, 3916, 3952, 4037], 'measurement': [21, 254, 3053], 'techniques.': [22, 255], 'CRAC': [23, 56, 208, 214, 256, 289, 441, 447, 769, 827, 912, 1199, 1241, 1472, 1483, 1512, 1531, 1608], 'were': [25, 258, 1665, 1700, 1716, 1741, 1757, 1888, 1950, 1987, 2006, 2043, 2232, 2278, 2303, 2314, 2374, 2410, 2548, 2608, 3151, 3172, 3377, 3650, 3758, 3880, 4000, 4051], 'activated': [26, 259], 'by': [27, 72, 82, 103, 117, 139, 147, 155, 159, 260, 305, 315, 336, 350, 372, 380, 388, 392, 476, 497, 528, 571, 629, 1220, 1522, 1594, 1610, 2268, 2272, 2280, 2316, 2645, 2669, 2749, 2759, 2773, 3102, 3252, 3494, 3629, 4025, 4034], 'passively': [28, 261], 'depleting': [29, 262], 'intracellular': [30, 43, 108, 263, 276, 341, 473, 486, 840, 1221, 1403, 1590, 2587, 2764, 3297, 3398], 'stores': [32, 102, 265, 335, 475, 576, 1405, 3757, 3779, 4206], 'the': [34, 89, 112, 140, 180, 224, 267, 322, 345, 373, 413, 457, 470, 494, 506, 563, 776, 837, 879, 909, 953, 969, 1134, 1138, 1231, 1240, 1383, 1394, 1465, 1480, 1499, 1541, 1554, 1619, 1742, 1760, 1789, 1822, 1990, 1998, 2067, 2090, 2100, 2126, 2156, 2176, 2194, 2226, 2242, 2259, 2262, 2282, 2296, 2317, 2322, 2326, 2348, 2453, 2471, 2513, 2527, 2540, 2614, 2637, 2670, 2688, 2760, 2997, 3005, 3045, 3048, 3079, 3086, 3094, 3109, 3118, 3124, 3140, 3158, 3202, 3230, 3241, 3255, 3259, 3263, 3278, 3281, 3285, 3289, 3302, 3328, 3334, 3357, 3361, 3380, 3395, 3418, 3442, 3465, 3503, 3530, 3538, 3555, 3564, 3598, 3605, 3618, 3644, 3657, 3700, 3721, 3752, 3763, 3766, 3793, 3804, 3810, 3825, 3946, 3950, 3957, 4007, 4014, 4055, 4070, 4091, 4108, 4147, 4170, 4194, 4211, 4221, 4341, 4352], 'absence': [35, 268, 2227, 4056], 'extracellular': [37, 270, 3497], 'Ca2+.': [38, 271, 3498, 3717], 'Under': [39, 272, 3776, 3897], 'conditions': [40, 273, 2387, 3549, 3899], 'moderate': [42, 275], 'buffering,': [45, 278], 'elevating': [46, 279], '[Ca2+]o': [47, 280, 1312, 2805], 'to': [48, 126, 206, 218, 281, 359, 439, 451, 613, 774, 833, 875, 908, 968, 988, 1224, 1235, 1470, 1529, 1600, 1614, 1882, 1902, 1977, 2008, 2015, 2021, 2096, 2111, 2140, 2167, 2200, 2451, 2466, 2500, 2596, 2654, 2660, 2692, 2699, 2797, 2808, 2957, 2996, 3013, 3031, 3156, 3174, 3187, 3206, 3272, 3300, 3386, 3417, 3427, 3483, 3511, 3528, 3532, 3547, 3576, 3593, 3625, 3643, 3671, 3675, 3692, 3714, 3732, 3749, 3770, 3783, 3891, 3893, 3932, 3972, 3982, 3990, 3993, 4010, 4012, 4068, 4112, 4138, 4158, 4181, 4193, 4316, 4350], '22': [49, 282, 1802, 2597, 2809, 3175, 3428, 3506, 3697, 3715, 3894, 4159], 'mM': [50, 283, 1680, 1684, 1722, 1792, 1795, 1798, 1803, 1809, 1817, 1825, 1829, 1836, 1839, 1843, 1846, 1851, 1854, 1858, 1861, 2034, 2041, 2598, 2734, 2810, 3176, 3268, 3332, 3354, 3429, 3507, 3698, 3716, 3895, 3902, 4160, 4164], 'initiated': [51, 284], 'an': [52, 83, 285, 316, 1476, 1931, 1953, 1958, 2463, 2813, 2946, 3991, 4182], 'inward': [53, 286, 2604, 2689, 2706, 2814], 'current': [54, 215, 287, 448, 2132, 2206, 2223, 2312, 2616, 2620, 2652, 2682, 2704, 2815, 2969, 3001, 3049, 3149, 3231, 3290, 3303, 3722, 4217], 'through': [55, 198, 288, 431, 878, 1226, 1506, 2066, 2294, 2484], 'that': [58, 92, 120, 166, 195, 291, 325, 353, 399, 428, 573, 780, 904, 962, 999, 1211, 1400, 1589, 1995, 2703, 3111, 3123, 3248, 3315, 3615, 3649, 3665, 3727, 3820, 3968, 4098, 4202], 'declined': [59, 292, 3691, 3953], 'slowly': [60, 293, 1526, 2602, 2978], 'with': [61, 105, 294, 338, 1550, 1553, 1873, 1895, 1910, 1930, 1952, 2032, 2039, 2118, 2363, 2369, 2376, 2437, 2477, 2788, 2951, 2982, 3117, 3168, 3217, 3266, 3344, 3900, 3925, 3945, 3998, 4002, 4162, 4368], 'a': [62, 73, 148, 295, 306, 381, 930, 950, 992, 1003, 1216, 1300, 1687, 1903, 1942, 2152, 2187, 2290, 2413, 2419, 2431, 2438, 2447, 2478, 2592, 2601, 2789, 2932, 2965, 2983, 3218, 3224, 3235, 3345, 3484, 3522, 3544, 3577, 3632, 3678, 3693, 3735, 3787, 3813, 3912, 3933, 4035, 4120, 4252], 'half-time': [63, 296], '~30': [65, 298], 's.': [66, 299, 2174, 3228], 'This': [67, 300, 523, 984, 1410, 2107, 3042], 'slow': [68, 115, 134, 202, 301, 348, 367, 435, 1295, 2579, 2998, 3003, 3057, 3087, 3106, 3127, 3162, 3286, 3316, 3338, 3401, 3477, 3572, 3661, 3794, 3904, 3973, 4066, 4125, 4139, 4148, 4179, 4356], 'inactivation': [69, 116, 135, 302, 349, 368, 1260, 1296, 2580, 2664, 2939, 3088, 3128, 3220, 3317, 3321, 3478, 3573, 3619, 3662, 3686, 3728, 3795, 3905, 3975, 4067, 4126, 4180], 'evoked': [71, 304], 'rise': [74, 307, 3347, 3788], '[Ca2+]i,': [76, 309, 3790], 'as': [77, 310, 614, 1002, 1718, 1871, 2045, 2050, 2151, 2331, 2337, 2554, 2711, 2822, 3002, 3059, 3190, 3240, 3389, 4073, 4094], 'it': [78, 311, 922, 1587, 2821, 3490, 3666], 'effectively': [80, 313], 'suppressed': [81, 314], 'elevated': [84, 317, 1524, 2139], 'level': [85, 318, 838, 3578, 3695, 3935], 'EGTA': [87, 320, 1847, 1862, 2988, 3205, 3269, 3355], 'pipette': [91, 324, 1913, 2000, 2372, 2790, 3264, 3358], 'prevented': [93, 138, 326, 371, 1549, 4065], 'increases': [94, 327], '[Ca2+]i.': [96, 329], 'Blockade': [97, 330], 'uptake': [100, 333], 'into': [101, 334, 4044], 'thapsigargin': [104, 337, 2121], 'or': [106, 188, 339, 421, 1313, 1723, 1801, 1849, 2267, 2618, 2725, 3674, 3772], 'without': [107, 340, 979, 3761], 'inositol': [109, 342, 477], '1,4,5-trisphosphate': [110, 343, 478], 'reduced': [111, 344, 3284, 3574, 3910], 'extent': [113, 346, 3531, 3559, 4016, 4072, 4185], '~50%,': [118, 351], 'indicating': [119, 352, 3726, 4097, 4201], 'store': [121, 354, 906, 1468, 1538, 2068, 2575, 3969, 3995, 4018, 4099, 4133], 'refilling': [122, 355, 1401, 1469, 1546, 3970, 4100, 4136], 'normally': [123, 356], 'contributes': [124, 357, 3971, 4137], 'significantly': [125, 358], 'this': [127, 360, 1631, 2057, 2708, 2992, 3008, 3136, 3373, 3436, 3516, 3719, 3800, 3985], 'process.': [128, 361], 'The': [129, 362, 601, 1915, 2054, 2457, 3076, 3211, 3293, 3558, 3602, 3978, 4020], 'store-independent': [130, 191, 363, 424], '(thapsigargin-insensitive)': [131, 364], 'portion': [132, 365, 1629], 'largely': [137, 370, 3359], 'protein': [141, 183, 374, 416, 4361], 'phosphatase': [142, 171, 375, 404, 4348], 'inhibitor,': [143, 376], 'okadaic': [144, 377, 1706, 4344], 'acid,': [145, 378, 1707, 4251], 'structurally': [149, 382], 'related': [150, 383], 'compound,': [151, 384], '1-norokadaone,': [152, 385, 1708], 'but': [153, 386, 1382, 2011], 'not': [154, 387, 915, 1387, 1490, 1515, 2012, 2044, 2060, 2123, 2239, 2721, 3011, 3608, 3668, 3730, 3988, 4052, 4060, 4102, 4208], 'calyculin': [156, 389, 1710], 'A': [157, 161, 390, 394, 1390, 1628, 1711, 1729, 3410], 'nor': [158, 391], 'cyclosporin': [160, 393], 'FK506': [163, 396, 1736], 'at': [164, 199, 397, 432, 1595, 1692, 1752, 1927, 1941, 2155, 2305, 2324, 3379, 3515], 'concentrations': [165, 398], 'fully': [167, 400, 3821, 3983], 'inhibit': [168, 207, 401, 440], 'calcineurin': [169, 402], '(protein': [170, 403], '2B)': [172, 405], 'cells.': [175, 408, 1627], 'These': [176, 409, 2929, 3312, 3965], 'results': [177, 410, 2344, 3313, 3654, 3966, 4118], 'argue': [178, 411], 'against': [179, 412], 'involvement': [181, 414], 'phosphatases': [184, 417, 4256, 4362], '1,': [185, 418, 2181], '2A,': [186, 419], '2B,': [187, 420], '3': [189, 422, 1816, 2136, 2191, 2782, 3888, 4079], 'inactivation.': [192, 425, 2213, 3107, 3163, 4115, 4140, 4357], 'We': [193, 426, 4338], 'conclude': [194, 427], 'calcium': [196, 429, 615, 989, 3159], 'acts': [197, 430], 'least': [200, 433, 1596], 'two': [201, 434, 1520, 2501], 'negative': [203, 436, 1503], 'feedback': [204, 211, 437, 444, 1504, 1606], 'pathways': [205, 438, 1505, 1599], 'channels.': [209, 442, 1532], 'Slow': [210, 443, 2745, 3750, 4249], 'inhibition': [212, 445, 1219, 3402], 'is': [216, 449, 493, 781, 1195, 1399, 1475, 1535, 1547, 1612, 2667, 2705, 3010, 3100, 3304, 3318, 3324, 3342, 3366, 3415, 3433, 3481, 3607, 3623, 3667, 3687, 3729, 3987, 4101, 4207], 'likely': [217, 450, 1613], 'play': [219, 452, 1215], 'important': [220, 453, 1477], 'roles': [221, 454], 'controlling': [223, 456], 'duration': [225, 458, 2454, 3279], 'dynamic': [227, 460], 'behavior': [228, 461], 'receptor-generated': [230, 463], 'signals.': [232, 465], 'INTRODUCTIONIn': [466], 'many': [467], 'nonexcitable': [468, 1626], 'cells,': [469, 611], 'depletion': [471, 907, 2069, 2585, 2762], '(IP3)1': [479], '1The': [480], 'abbreviations': [481], 'used': [482, 1701], 'are:': [483], 'IP3inositol': [484], '1,4,5-trisphosphate[Ca2+]free': [485], 'concentrationICRACCa2+': [488], 'currentTGthapsigarginCsAcyclosporin': [491], 'A.': [492, 686, 695, 737, 746, 792, 801, 894, 1057, 1244, 1279, 1350, 1359, 1573, 1641, 1768, 2073, 2394, 2557, 2869, 2878, 2915, 3062], 'primary': [495], 'mechanism': [496, 1534], 'which': [498, 872, 1474, 1507, 1523, 2295, 2325, 2793, 3533, 3571], 'surface': [500], 'receptors': [501], 'activate': [502, 2112], 'influx': [504, 779, 965, 990, 2675, 3196, 4320], 'across': [505], 'plasma': [507, 1139, 3256], 'membrane(1Putney': [508], 'Jr.,': [509, 535, 1038, 1160], 'J.W.': [510, 536, 1039, 1161], 'Bird': [511, 1162], 'G.S.J.': [512, 1036, 1163], 'Endocrinol.': [513, 1164], 'Rev.': [514, 1165], '1993;': [515, 676, 696, 711, 747, 762, 802, 941, 1026, 1043, 1063, 1082, 1100, 1144, 1166, 1271, 1340, 1360, 1375, 1565, 2859, 2879, 2894, 4330], '14:': [516, 1167], '610-631Crossref': [517, 1168], 'PubMed': [518, 542, 596, 649, 662, 682, 699, 750, 805, 852, 867, 898, 944, 1032, 1049, 1069, 1088, 1106, 1126, 1147, 1169, 1190, 1253, 1288, 1326, 1346, 1363, 1431, 1459, 1582, 1652, 1780, 2082, 2403, 2566, 2832, 2845, 2865, 2882, 2924, 3071, 3851, 3871, 4288, 4308, 4333, 4388], 'Scopus': [519, 543, 597, 650, 663, 700, 714, 751, 765, 806, 853, 868, 899, 945, 1148, 1170, 1191, 1254, 1274, 1289, 1327, 1364, 1378, 1432, 1444, 1460, 1568, 1583, 1653, 1781, 2083, 2404, 2567, 2833, 2846, 2883, 2897, 2925, 3072, 3852, 4289, 4309, 4334, 4389], '(483)': [520, 1171], 'Google': [521, 545, 599, 652, 665, 683, 702, 716, 729, 753, 767, 808, 821, 855, 870, 901, 947, 1033, 1050, 1070, 1089, 1107, 1127, 1150, 1172, 1193, 1256, 1276, 1291, 1329, 1347, 1366, 1380, 1434, 1446, 1462, 1570, 1585, 1655, 1783, 2085, 2406, 2569, 2835, 2848, 2866, 2885, 2899, 2912, 2927, 3074, 3839, 3854, 3872, 4291, 4311, 4336, 4391], 'Scholar).': [522, 546, 600, 768, 822, 1292, 1463, 1784, 2086, 2407, 2928, 3075, 4337], 'phenomenon': [524], 'first': [526], 'proposed': [527, 1001, 1154], 'Putney': [529, 1037], 'termed': [531], 'capacitative': [532, 553, 1009, 1395, 1486, 1602, 2205, 2222, 2726, 4318], 'entry(2Putney': [534], 'Cell': [537, 644, 847, 1321, 2253, 2827], 'Calcium.': [538], '1990;': [539, 1441, 4285, 4302, 4382], '11:': [540, 4286], '611-624Crossref': [541], '(1257)': [544], 'Multiple': [547], 'types': [548, 624], 'ion': [550], 'underlying': [552, 1384], 'entry': [555, 1397, 3245], 'have': [556, 771, 830, 1152, 1209, 1386, 2388], 'been': [557, 772, 831, 917, 1153, 1306, 1388, 1413, 1492, 1516, 1634, 2389, 4314], 'identified': [558, 2820], 'different': [560, 3645], 'cells': [561, 608, 961, 1417, 1664, 1696, 2027, 2049, 2409, 2758, 2980, 3155, 3166, 3565, 3569, 3923, 4045, 4229], 'on': [562, 1239, 1299, 1537, 1607, 2430, 2934, 3400, 4216, 4248], 'basis': [564], 'their': [566, 630, 732, 1898], 'permeability': [568, 3764], 'activation': [570, 786, 910, 1013], 'agents': [572], 'empty': [574], '(for': [577, 1155], 'review,': [578], 'see': [579, 1157], 'Ref.': [580], '3Fasolato': [581, 1175], 'C.': [582, 937, 1018, 1176], 'Innocenti': [583, 1177], 'B.': [584, 1178, 1772, 3412], 'Pozzan': [585, 1179], 'T.': [586, 1180, 4279, 4283], 'Trends': [587, 1181, 4299, 4379], 'Pharmacol.': [588, 1182], 'Sci.': [589, 692, 743, 798, 891, 1183, 1356, 2875, 4301, 4381], '1994;': [590, 726, 818, 864, 895, 1120, 1184, 1428, 1646, 2909, 3836, 3848, 4402], '15:': [591, 1185, 4303, 4383], '77-83Abstract': [592, 1186], 'Full': [593, 679, 1029, 1046, 1066, 1085, 1103, 1123, 1187, 1343, 1649, 2862, 3868, 4305, 4385], 'Text': [594, 680, 1030, 1047, 1067, 1086, 1104, 1124, 1188, 1344, 1650, 2863, 3869, 4306, 4386], 'PDF': [595, 681, 1031, 1048, 1068, 1087, 1105, 1125, 1189, 1345, 1651, 2864, 3870, 4307, 4387], '(437)': [598, 1192], 'depletion-activated': [602, 626], 'present': [605, 4168], 'mast': [607], 'referred': [612], 'channels,': [619, 1473], 'are': [620, 1201, 2216, 2310, 2335, 2354, 2643, 2720, 3130, 3441, 4220], 'distinguished': [621], 'from': [622, 952, 982, 1890, 2161, 2186, 2203, 2258, 2462, 2512, 2533, 2550, 2613, 2658, 2697, 2806, 3405, 3435, 4227], 'other': [623, 638, 1542, 4347], 'high': [631, 3814], 'selectivity': [632], 'for': [633, 783, 1007, 1989, 2056, 2218, 2636, 2687, 2713, 2723, 2781, 3182, 3277, 3306, 3521, 3588, 3681, 3708, 3887, 4210], 'over': [635, 1261, 3223, 3929, 3956], 'monovalent': [636], 'divalent': [639], 'cations(4Lewis': [640], 'R.S.': [641, 688, 739, 794, 844, 860, 1246, 1281, 1318, 1352, 1424, 1575, 1643, 2075, 2396, 2559, 2824, 2871, 2917, 3064, 3844], 'Cahalan': [642, 845, 886, 1319, 2825], 'M.D.': [643, 846, 887, 1320, 2826], 'Regul.': [645, 848, 1322, 2828], '1989;': [646, 849, 1323, 2829], '1:': [647, 850, 1324, 2830], '99-112Crossref': [648, 851, 1325, 2831], '(354)': [651, 854, 1328, 2834], 'Scholar,': [653, 666, 684, 703, 717, 754, 809, 856, 1034, 1051, 1108, 1277, 1330, 1348, 1367, 1435, 1447, 1571, 2836, 2849, 2867, 2886, 2900, 2913, 3840, 3855, 4292, 4392], '5Hoth': [654, 2837], 'M.': [655, 705, 756, 1020, 1265, 1369, 1449, 1559, 2838, 2888, 3859, 4265, 4273], 'Penner': [656, 706, 757, 1021, 1266, 1370, 1560, 2839, 2889], 'R.': [657, 707, 758, 858, 1022, 1267, 1371, 1422, 1437, 1561, 2543, 2840, 2890, 3842, 4269], 'Nature.': [658, 940, 1143, 2841, 4329], '1992;': [659, 1456, 2842], '355:': [660, 2843], '353-356Crossref': [661, 2844], '(1478)': [664, 2847], '6McDonald': [667, 1331, 2850], 'T.V.': [668, 721, 813, 1332, 2851, 2904, 3831], 'Premack': [669, 1333, 2852], 'B.A.': [670, 719, 811, 1334, 2853, 2902, 3829, 4396], 'Gardner': [671, 722, 814, 1335, 2854, 2905, 3832], 'P.': [672, 723, 815, 1074, 1336, 2855, 2906, 3833, 4294, 4374], 'J.': [673, 708, 724, 759, 816, 861, 1023, 1040, 1060, 1079, 1097, 1117, 1247, 1268, 1282, 1337, 1372, 1425, 1438, 1451, 1453, 1455, 1562, 1576, 1645, 2076, 2397, 2560, 2856, 2891, 2907, 2918, 3065, 3834, 3845, 3857, 3862], 'Biol.': [674, 1024, 1041, 1061, 1080, 1098, 1118, 1338, 2857, 3863], 'Chem.': [675, 1025, 1042, 1062, 1081, 1099, 1119, 1339, 2858, 3864], '268:': [677, 1027, 1044, 1064, 1083, 1101, 1341, 2860], '3889-3896Abstract': [678, 1342, 2861], '7Zweifach': [685, 1349, 2868], 'Lewis': [687, 738, 793, 859, 1245, 1280, 1351, 1423, 1574, 1642, 2074, 2395, 2558, 2870, 2916, 3063, 3843], 'Proc.': [689, 740, 795, 888, 1353, 2872], 'Natl.': [690, 741, 796, 889, 1354, 2873], 'Acad.': [691, 742, 797, 890, 1355, 2874], 'U.': [693, 744, 799, 892, 1357, 2876], 'S.': [694, 745, 800, 893, 1116, 1358, 2877, 4261], '90:': [697, 748, 803, 1361, 2880], '6295-6299Crossref': [698, 749, 804, 1362, 2881], '(690)': [701, 752, 807, 1365, 2884], '8Hoth': [704, 755, 1368, 2887], 'Physiol.': [709, 760, 863, 1249, 1269, 1284, 1373, 1427, 1439, 1563, 1578, 2078, 2399, 2562, 2892, 2920, 3067, 3847], '(Lond.).': [710, 761, 1270, 1374, 1440, 1564, 2893], '465:': [712, 763, 1272, 1376, 1566, 2895], '359-386Crossref': [713, 764, 1273, 1377, 1567, 2896], '(656)': [715, 766, 1275, 1379, 1569, 2898], '9Premack': [718, 810, 2901], 'McDonald': [720, 812, 2903, 3830], 'Immunol.': [725, 817, 2908, 3835], '152:': [727, 819, 2910, 3837], '5226-5240PubMed': [728, 820, 2911, 3838], 'Scholar)': [730, 948, 1151, 3873, 4312], 'extremely': [733], 'small': [734, 993], 'unitary': [735], 'conductance(7Zweifach': [736], 'shown': [773, 832, 2178, 2628, 3371, 4234], 'underlie': [775], 'mitogen-stimulated': [777], 'essential': [782, 1616, 3680], 'following': [787, 1308, 2574, 3637, 3786], 'receptor': [790], 'engagement(7Zweifach': [791], 'Furthermore,': [823, 1498, 4062], 'periodic': [824], 'changes': [825, 4130], 'channel': [828, 1242, 3472], 'activity': [829, 985], 'generate': [834], 'oscillations': [835], 'free': [841, 1878], '([Ca2+]i)(4Lewis': [843], '10Dolmetsch': [857, 3841], 'Gen.': [862, 1248, 1283, 1426, 1577, 2077, 2398, 2561, 2919, 3066, 3846], '103:': [865, 1429, 3849], '365-388Crossref': [866, 1430, 3850], '(151)': [869, 1433, 3853], 'Scholar),': [871, 1071, 1090, 1128, 1257, 1381, 1586], 'may': [873, 1214, 1509, 3468, 3641], 'serve': [874], 'enhance': [876, 4317], 'signaling': [877], 'receptor(11Negulescu': [882], 'P.A.': [883], 'Shastri': [884], 'N.': [885, 1747], '91:': [896], '2873-2877Crossref': [897], '(227)': [900], 'Scholar).The': [902], 'signal': [903, 2459], 'couples': [905], 'has': [914, 1305, 1412, 1489, 1514, 1633, 4313], 'yet': [916, 1491], 'identified,': [918], 'principle': [921], 'could': [923], 'encompass': [924], 'diffusible': [925, 1004, 3736], 'and/or': [926], 'membrane-associated': [927], 'molecules.': [928], 'In': [929, 1293, 2175, 2991, 3020, 3132, 3537, 3567, 3718, 3921], 'recent': [931], 'study,': [932], 'Randriamampita': [933], 'Tsien': [935, 938], '(12Randriamampita': [936], 'R.Y.': [939], '364:': [942, 4331], '809-814Crossref': [943], '(785)': [946], 'isolated': [949], 'fraction': [951], 'cytoplasm': [954], 'stimulated': [956], 'human': [959, 1661], 'triggers': [963], 'when': [966, 1545, 1908], 'applied': [967], 'exterior': [970], 'astrocyte,': [972], 'neuroblastoma,': [973], 'macrophage': [975], 'lines,': [977], 'apparently': [978], 'releasing': [980], 'stores.': [983, 2766], 'attributed': [987], 'factor,': [991], '(<500': [994], 'Mr)': [995], 'nonproteinaceous': [996], 'phosphate-containing': [997], 'factor': [998, 3679], 'they': [1000], 'messenger': [1005], 'responsible': [1006, 4209], 'activating': [1008], 'entry.': [1011, 1604], 'Additional': [1012], 'mechanisms': [1014, 1385, 1521], 'involving': [1015], 'GTP-binding': [1016], 'proteins(13Fasolato': [1017], 'Hoth': [1019], '20737-20740Abstract': [1028], '14Bird': [1035], '21486-21488Abstract': [1045], '15Jaconi': [1052], 'M.E.E.': [1053], 'Lew': [1054], 'D.P.': [1055], 'Monod': [1056], 'Krause': [1058], 'K.-H.': [1059], '26075-26078Abstract': [1065], 'tyrosine': [1072], 'kinases(16Sargeant': [1073], 'Farndale': [1075], 'R.W.': [1076], 'Sage': [1077], 'S.O.': [1078], '18151-18156Abstract': [1084], 'cGMP(17Bahnson': [1091], 'T.D.': [1092], 'Pandol': [1093], 'S.J.': [1094], 'Dionne': [1095], 'V.E.': [1096], '10808-10812Abstract': [1102], '18Xu': [1109], 'X.': [1110], 'Star': [1111], 'R.A.': [1112], 'Tortorici': [1113], 'G.': [1114, 1750], 'Muallem': [1115], '269:': [1121], '12645-12653Abstract': [1122], 'direct': [1130], 'physical': [1131], 'coupling': [1132], 'between': [1133, 1997], "store's": [1135], 'membrane': [1136, 1140, 3769], '(19Berridge': [1141], 'M.J.': [1142], '361:': [1145], '315-325Crossref': [1146], '(6147)': [1149], 'reviews,': [1156], 'Refs.': [1158], '1Putney': [1159], 'Scholar': [1173], 'Scholar).Little': [1194], 'known': [1196], 'about': [1197, 4069], 'how': [1198], 'turned': [1202], 'off': [1203, 1511], 'once': [1204, 2171], 'activated,': [1205], 'although': [1206], 'several': [1207], 'reports': [1208], 'demonstrated': [1210], 'increased': [1212, 3296], 'role.': [1217], 'appears': [1223, 1588], 'occur': [1225], 'multiple': [1227], 'mechanisms.': [1228], 'After': [1229, 2135, 2800, 3689], 'entering': [1230], 'cell,': [1232, 3720], 'binds': [1234], 'sites': [1236], 'probably': [1237], 'residing': [1238], 'itself(20Zweifach': [1243], '1995;': [1250, 1285, 1579, 2079, 2400, 2563, 2921, 3068], '105:': [1251, 1286, 1580, 2080, 2401, 2564, 2922, 3069], '209-226Crossref': [1252, 1287, 1581, 2081, 2402, 2565, 2923, 3070], '(330)': [1255, 1290, 1584, 2084, 2405, 2568, 2926, 3073], 'eliciting': [1258], 'rapid': [1259, 2938], 'tens': [1262], 'milliseconds(8Hoth': [1264], '20Zweifach': [1278, 1572, 2914], 'addition,': [1294], 'ICRAC': [1298, 2063, 2113, 2145, 2183, 2666, 2748, 2976, 3025, 3115, 3198, 3222, 3323, 3341, 3365, 3404, 3480, 3501, 3534, 3575, 3690, 3808, 3907, 3927, 4114, 4151], 'time': [1301, 2323, 2332, 3120, 3432, 3805, 3947, 3959], 'scale': [1302], 'seconds': [1304, 4041], 'observed': [1307, 4053], 'abrupt': [1309], 'elevation': [1310, 2803], 'global': [1314], 'rises': [1315], '[Ca2+]i(4Lewis': [1317], 'determined.': [1389], 'central': [1391], 'tenet': [1392], 'hypothesis': [1398], 'should': [1406, 3199], 'terminate': [1407], 'influx.': [1409], 'prediction': [1411], 'confirmed': [1414, 4030], 'intact': [1416], 'fluorescent': [1419], 'indicators(10Dolmetsch': [1421], '21Jacob': [1436], '421:': [1442], '55-77Crossref': [1443], '(203)': [1445], '22Montero': [1448], 'Alvarez': [1450], 'Garca-Sancho': [1452], 'Biochem.': [1454, 4300, 4380], '288:': [1457], '519-525Crossref': [1458], '(42)': [1461], 'However,': [1464, 3610], 'ability': [1466, 3294, 4342], 'close': [1471], 'test': [1478, 3475, 3799], 'role': [1481], 'entry,': [1488], 'examined': [1493, 3488], 'directly': [1494], 'patch-clamp': [1496, 1916, 2367], 'experiments.': [1497, 1704], 'presence': [1500, 3329, 3504, 3811], 'additional': [1502, 2116], 'turn': [1510], 'explored.This': [1517], 'paper': [1518], 'describes': [1519], 'feeds': [1527, 1592], 'back': [1528, 1593], 'inactivate': [1530], 'One': [1533], 'dependent': [1536], 'refilling,': [1539], 'while': [1540, 2784], 'operates': [1543], 'even': [1544], 'completely': [1548], 'thapsigargin.': [1551], 'Thus,': [1552, 3108], 'inclusion': [1555], 'fast': [1557, 2212, 3055, 3104, 3125, 3146], 'inactivation(8Hoth': [1558], 'three': [1597], 'independent': [1598, 3052], 'control': [1601, 2452], 'Autoregulatory': [1605], 'be': [1615, 1883, 2467, 3192, 3492, 3781], 'determining': [1618], 'character': [1620], 'receptor-stimulated': [1622], 'signals': [1624, 2536], 'work': [1632], 'reported': [1635, 4315], 'previously': [1636], 'abstract': [1638], 'form': [1639], '(23Zweifach': [1640], 'Biophys.': [1644], '66:': [1647], 'A153Abstract': [1648], '(36)': [1654], 'Scholar).EXPERIMENTAL': [1656], 'PROCEDURESCells': [1657], 'ReagentsJurkat': [1659], 'E6-1': [1660], 'maintained': [1666], 'complete': [1668, 3552], 'medium': [1669], 'containing': [1670], 'RPMI': [1671], '1640': [1672], '10%': [1674], 'heat-inactivated': [1675], 'fetal': [1676], 'bovine': [1677], 'serum,': [1678], '2': [1679, 1800, 1884, 2173, 2611, 3036], 'glutamine,': [1681], '25': [1683], 'HEPES,': [1685], '6%': [1688], 'CO2': [1689], 'humidified': [1690], 'atmosphere': [1691], '37°C.': [1693], 'Log': [1694], 'phase': [1695], '(0.2-1.2': [1697], '×': [1698], '106/ml)': [1699], 'all': [1703, 2149, 3021], 'Thapsigargin,': [1705], '(LC': [1712], 'Pharmaceuticals,': [1713], 'Woburn,': [1714], 'MA)': [1715, 1938], 'prepared': [1717], 'stocks': [1719], '1': [1721, 1797, 2119, 4142, 4257, 4363], '100': [1724, 2377, 3275, 3930], 'μM': [1725, 2120, 2378, 4004, 4027, 4143, 4191], 'Me2SO.': [1727], 'Cyclosporin': [1728], '(2': [1730], 'mg/ml': [1731], '2%': [1733], 'ethanol)': [1734, 1740], '(50': [1737], 'μg/ml': [1738], 'generous': [1743], 'gift': [1744], 'Drs.': [1746], 'Clipstone': [1748], 'Crabtree': [1751], 'Stanford': [1753], 'University.Patch-Clamp': [1754], 'RecordingPatch-clamp': [1755], 'experiments': [1756, 2031, 2150, 2365, 2772, 3308, 3406, 3622, 3753, 4033, 4231], 'conducted': [1758, 2304], 'standard': [1761], 'configuration(24Hamill': [1765], 'O.P.': [1766], 'Marty': [1767], 'Neher': [1769], 'E.': [1770], 'Sakmann': [1771], 'Sigworth': [1773], 'F.J.': [1774, 4281], 'Pflügers': [1775], 'Arch.': [1776], '1981;': [1777], '391:': [1778], '85-100Crossref': [1779], '(15093)': [1782], 'Extracellular': [1785], "Ringer's": [1786, 1814, 2003, 2779, 3706, 3884], 'solution': [1787, 2780, 2791, 3265, 3707, 4009, 4196], 'contained': [1788, 1815, 1821], 'following:': [1790, 1823], '155': [1791], 'NaCl,': [1793], '4.5': [1794], 'KCl,': [1796], 'MgCl2,': [1799], 'CaCl2,': [1804, 1837, 1852], '10': [1805, 1828], 'mMD-glucose,': [1806], '5': [1808, 1876, 1945, 2798], 'Na-HEPES': [1810], '(pH': [1811, 1831], '7.4).': [1812], 'Ca2+-free': [1813, 2097, 2778, 3548, 3705, 3883, 4047, 4174], 'MgCl2.': [1818], 'Internal': [1819, 2728], 'solutions': [1820, 1870, 2001, 2277, 2298, 2373], '140': [1824], 'cesium': [1826, 1911, 2730], 'aspartate,': [1827], 'Cs-HEPES': [1830], '7.2),': [1832], 'either': [1834, 2257], '0.66': [1835], '11.68': [1838], 'EGTA,': [1840, 1855, 3333], '3.01': [1842], 'MgCl2': [1844, 1859], '(12': [1845], 'solution)': [1848], '0.066': [1850], '1.2': [1853, 2033, 2733, 3331, 3901, 4163], '2.01': [1857], '(1.2': [1860, 2989], 'solution).': [1863], 'Free': [1864], '[Ca2+]': [1865, 2794, 3362, 4153], 'both': [1867, 3103, 3112], 'these': [1869, 2771, 3621, 3653, 3777, 3898, 4117], 'measured': [1872, 2147, 2185, 2224, 2525, 2609, 3024, 3378, 3803], 'indo-1': [1874, 2379], 'nM;': [1877], '[Mg2+]': [1879], 'calculated': [1881], 'mM.': [1885], 'Recording': [1886, 2386], 'electrodes': [1887], 'pulled': [1889], '100-μl': [1891], 'pipettes': [1892], '(VWR),': [1893], 'coated': [1894], 'Sylgard': [1896], 'near': [1897], 'tips,': [1899], 'fire-polished': [1901], 'resistance': [1904, 2236, 2244], '2-6': [1906], 'megaohms': [1907], 'filled': [1909], 'aspartate': [1912, 2731], 'solution.': [1914, 2004], 'output': [1917], '(Axopatch': [1918], '200,': [1919], 'Axon': [1920], 'Instruments,': [1921], 'Foster': [1922], 'City,': [1923], 'CA)': [1924], 'filtered': [1926], '1.5': [1928], 'kHz': [1929], '8-pole': [1932], 'Bessel': [1933], 'filter': [1934, 2424], '(Frequency': [1935], 'Devices,': [1936], 'Haverhill,': [1937], 'digitized': [1940], 'rate': [1943, 3242], 'kHz.': [1946], 'Stimulation': [1947], 'performed': [1951], 'Apple': [1954], 'Macintosh': [1955], 'computer': [1956], 'driving': [1957], 'ITC-16': [1959], 'interface': [1960], '(Instrutech,': [1961], 'Elmont,': [1962], 'NY)': [1963], 'PulseControl': [1966], 'software': [1967], 'extensions': [1968], '(Jack': [1969], 'Herrington': [1970], 'Richard': [1972], 'Bookman,': [1973], 'University': [1974], 'Miami)': [1976], 'Igor': [1978], 'Pro': [1979], '(WaveMetrics,': [1980], 'Inc.,': [1981], 'Lake': [1982], 'Oswego,': [1983], 'OR).': [1984, 2385], 'Command': [1985], 'potentials': [1986], 'corrected': [1988, 2217, 2722], '−12': [1991, 2162, 2659], 'mV': [1992, 2163, 2169, 2701, 2959, 3033, 3388], 'junction': [1993], 'potential': [1994, 2955], 'exists': [1996], 'aspartate-based': [1999], 'Cells': [2005, 3879], 'allowed': [2007, 3510, 3550, 3591], 'settle': [2009], 'onto': [2010], 'firmly': [2013], 'adhere': [2014], 'glass': [2016], 'coverslip': [2017], 'chambers': [2018], 'shortly': [2019], 'prior': [2020, 3890], 'each': [2022, 2092, 2197, 2775, 3423], 'experiment.': [2023], 'Adherent': [2024], 'nonadherent': [2026, 2052], 'behaved': [2028], 'identically': [2029], 'EGTAi;': [2035], 'however,': [2036], 'currents': [2037, 2270, 3081, 3096, 3370, 4224], 'obtained': [2038], '12': [2040, 3267, 3353], 'EGTAi': [2042], 'sustained': [2046], 'adherent': [2048], 'ones.': [2053], 'reason': [2055], 'difference': [2058], 'investigated': [2061], 'further.': [2062], 'induced': [2065, 2668, 2753], 'protocol': [2070, 3043], 'described': [2071, 2390, 2555, 3060, 3143, 3390, 3754], 'previously(20Zweifach': [2072, 2393, 2556, 3061], 'Following': [2087], 'formation': [2088], 'gigaseal,': [2091], 'exposed': [2095, 3173, 4157], "Ringer's,": [2098], 'configuration': [2104], 'established.': [2106], 'procedure': [2108], 'sufficient': [2110], 'maximally,': [2114], 'because': [2115], 'pretreatment': [2117], 'did': [2122], 'further': [2124, 3133, 3655, 4199], 'increase': [2125, 2672, 3212, 3914, 4013], 'average': [2127, 2154, 2189, 4183, 4222], 'initial': [2128, 3599, 3940], 'size': [2129, 3046], '(Table': [2133], 'I).': [2134, 3920, 3964], 'min,': [2137], '[Ca2+]owas': [2138], '2-22': [2141], 'mM,': [2142], 'steady-state': [2144, 2619, 3095, 3694, 3934], '5-10-ms': [2153], 'end': [2157, 3381], '200-ms': [2159, 2655], 'pulses': [2160, 2627, 2657, 2943, 3030, 3385], '(the': [2164], 'holding': [2165], 'potential)': [2166], '−132': [2168, 2661, 3032, 3387], 'delivered': [2170, 3034], 'every': [2172, 2610, 3035], 'experiment': [2177, 3282, 3424], 'Fig.': [2180, 2974, 3040, 3310, 3392, 3542, 4084], 'peak': [2182, 2615, 3080, 3236, 3600], '1-ms': [2188], 'beginning': [2190], 'ms': [2192], 'after': [2193, 2584, 3425], 'start': [2195], 'hyperpolarizing': [2198, 2625, 2941, 3028, 3383], 'pulse': [2199], 'minimize': [2201], 'contributions': [2202], 'uncompensated': [2204], '(time': [2207], 'constant,': [2208], '<1': [2209], 'ms)': [2210], 'All': [2214, 3369], 'data': [2215, 2309], 'leak': [2219, 2724], 'residual': [2221], 'Cao2+.': [2229, 3896], 'Leak': [2230], 'conductances': [2231], '20-100': [2233], 'picosiemens.': [2234], 'Series': [2235], 'compensation': [2237], 'employed,': [2240], 'since': [2241, 3194], 'series': [2243], '(4-25': [2245], 'megaohms)': [2246], 'produced': [2247], 'voltage': [2248, 2626, 2656, 2693, 2709, 2942, 3029, 3384], 'errors': [2249], '<3': [2251], 'mV.': [2252, 2662], 'capacitance': [2254], 'determined': [2256, 2549, 3101], 'settings': [2260], 'capacitance-compensation': [2265], 'circuitry,': [2266], 'integrating': [2269], 'elicited': [2271, 2622, 2812], '10-mV': [2273], 'depolarizing': [2274], 'steps.': [2275], 'External': [2276], 'changed': [2279], 'positioning': [2281], '~1': [2284], 'mm': [2285], 'inside': [2286], 'one': [2287, 4155], 'barrel': [2288], 'perfusion': [2291], 'tube': [2292], 'array': [2293], 'desired': [2297], 'flowed': [2299], '(<0.1': [2300], 'ml/min).': [2301], 'Experiments': [2302, 3997], '22-25°C.': [2306], 'Where': [2307], 'normalized': [2308, 3416, 4223], 'presented,': [2311], 'amplitudes': [2313], 'divided': [2315], "current's": [2318, 3556], 'maximal': [2319], 'value,': [2320], 'maximum': [2327, 3419], 'occurred': [2328], 'defined': [2330], 'zero.': [2333], 'Data': [2334, 2606, 2715, 4219], 'presented': [2336, 3612], 'mean': [2338, 3443], '±': [2339, 2421, 2486, 2490, 3444, 3581, 3595, 4225], 'S.E.': [2340, 3445, 4226], 'Statistical': [2341], 'significance': [2342], 'assessed': [2346], 'Mann-Whitney': [2349], 'U': [2350], 'test,': [2351], 'differences': [2353], 'considered': [2355], 'significant': [2356, 2968], 'if': [2357], 'p': [2358], '<': [2359], '0.01.': [2360], 'Measurements': [2362], 'Indo-1-For': [2364], 'combining': [2366], 'measurements,': [2371], 'supplemented': [2375], 'pentapotassium': [2380], 'salt': [2381], '(Molecular': [2382], 'Probes,': [2383], 'Eugene,': [2384], 'detail': [2392], 'Briefly,': [2408], 'illuminated': [2411], '75W': [2414], 'xenon': [2415], 'arc': [2416], 'lamp': [2417], '360': [2420], '5-nm': [2422], 'interference': [2423, 2493], '(Omega': [2425], 'Optical,': [2426], 'Brattleboro,': [2427, 2498], 'VT)': [2428, 2499], 'mounted': [2429], 'Nikon': [2432, 2439], 'Diaphot': [2433], 'inverted': [2434], 'microscope': [2435], 'equipped': [2436], 'Fluor': [2440], '40×': [2441], 'objective': [2442], '(numerical': [2443], 'aperature,': [2444], '1.3)': [2445], 'transistor-transistor': [2448], 'logic-controlled': [2449], 'shutter': [2450], 'illumination.': [2456], 'emission': [2458], 'collected': [2461], 'area': [2464], 'adjusted': [2465], 'slightly': [2468], 'larger': [2469], 'than': [2470], 'cell.': [2472], 'Emitted': [2473], 'light': [2474], 'split': [2476], '440-nm': [2479], 'dichroic': [2480], 'mirror': [2481], 'passed': [2483], '405': [2485], '15': [2487], '480': [2489], '12.5': [2491], 'nm': [2492], 'filters': [2494], '(Chroma': [2495], 'Technology': [2496], 'Corp.,': [2497, 2506], 'photomultiplier': [2502], 'tubes': [2503], '(HC124-02,': [2504], 'Hamamatsu': [2505], 'Bridgewater,': [2507], 'NJ).': [2508], 'estimated': [2511], 'relation': [2514, 2686, 2950], '=': [2516, 4078], 'K∗(R': [2517], '−': [2518], 'Rmin)/(Rmax': [2519], '-': [2520], 'R).': [2521], 'Background': [2522], 'fluorescence': [2523, 2535], 'cell-attached': [2528], 'mode': [2529], 'subtracted': [2532], 'subsequent': [2534, 3337, 3375, 3583], 'before': [2537, 3185], 'calculation': [2538], '405/480': [2541], 'ratio,': [2542], 'K∗,': [2544], 'Rmin,': [2545], 'Rmax': [2547], 'vivo': [2552], 'calibrations': [2553], 'Scholar).Table': [2570], 'IICRAC': [2571], 'depletionFigure': [2576], '1:Fast': [2577], 'ICRAC.': [2582, 2714, 3797, 3977], 'A,': [2583, 3326, 4141], 'stores,': [2589], 'exposure': [2590, 3426, 3546, 3892], 'Cao2+': [2599, 2935, 3508, 3518, 3587, 3640, 4161], 'induces': [2600], 'decaying': [2603], 'current.': [2605, 2690], 'points': [2607], 's': [2612, 3037, 3184, 3590, 3710, 3931], '(○)': [2617], '(□)': [2621], 'during': [2623, 2940, 3026, 4169], 'brief': [2624, 3027], 'B': [2630, 2640, 2717], '(see': [2631], '"Experimental': [2632], 'Procedures").': [2633], 'Collection': [2634], 'times': [2635], 'traces': [2638], 'C': [2642, 2719], 'indicated': [2644], 'i-iii': [2646], 'a-c,': [2648], 'respectively.': [2649], 'B,': [2650, 3352, 4176], 'selected': [2651], 'responses': [2653], 'Rapid': [2663], 'sudden': [2671], 'upon': [2676], 'hyperpolarization.': [2677], 'Dashed': [2678], 'line': [2679], 'indicates': [2680], 'zero': [2681], 'level.': [2683], 'C,': [2684, 3394], 'current/voltage': [2685], 'Responses': [2691], 'ramps': [2694], '(200-ms': [2695], 'duration)': [2696], '−120': [2698], '+50': [2700, 2958], 'show': [2702], 'range': [2710], 'expected': [2712, 3193, 3782], 'currents.': [2727], 'solution,': [2729], '+': [2732, 3885], 'EGTA.View': [2735], 'Large': [2736, 3449, 3738, 4237], 'Image': [2737, 3450, 3739, 4238], 'Figure': [2738, 3451, 3740, 4239], 'ViewerDownload': [2739, 3452, 3741, 4240], 'Hi-res': [2740, 3453, 3742, 4241], 'image': [2741, 3454, 3743, 4242], 'Download': [2742, 3455, 3744, 4243], '(PPT)RESULTSFast': [2743], 'Inactivation': [2746], 'Intracellular': [2750], 'Ca2+ICRAC': [2751], 'passive': [2761], 'Depletion': [2767], 'achieved': [2769], 'incubating': [2774], 'min': [2783, 3889], 'dialyzing': [2785], 'its': [2786, 3774, 3939], 'interior': [2787], 'buffered': [2796], 'nM.': [2799], 'such': [2801, 4049], 'treatment,': [2802], '0': [2807, 3586], 'rapidly': [2811], '(Fig.': [2816, 2936, 2944, 2960, 3082, 3097, 3209, 3291, 3917, 3942, 3961], '1)': [2817], 'whose': [2818], 'properties': [2819, 2930], 'ICRAC(4Lewis': [2823], 'included': [2931], 'dependence': [2933, 3160, 3659], '1A),': [2937], '1B),': [2945], 'inwardly': [2947], 'rectifying': [2948], 'current-voltage': [2949], 'no': [2952, 4198], 'clear': [2953], 'reversal': [2954], 'up': [2956], '1C),': [2961], 'voltage-independent': [2962], 'gating,': [2963], 'lack': [2966], 'noise.': [2970], 'As': [2971, 3229, 4081], 'illustrated': [2972], '1A,': [2975, 3083, 3098], 'decayed': [2977, 3928], 'dialyzed': [2981, 3167], 'relatively': [2984, 3180], 'low': [2985, 3169], 'amount': [2986], 'mM).': [2990], 'paper,': [2993], 'we': [2994, 3023, 3487, 3802], 'refer': [2995], 'decay': [2999, 3077, 3092, 3116, 3287], 'inactivation;': [3004], 'use': [3006], 'terminology': [3009], 'intended': [3012], 'imply': [3014], 'any': [3015], 'specific': [3016], 'type': [3017], 'mechanism.': [3019], 'experiments,': [3022], '(as': [3038], '1B).': [3041], 'optimizes': [3044], 'allows': [3051], 'inactivation,': [3058], 'squares)': [3084], 'reflects': [3085], 'process': [3089, 3986, 4122], 'alone,': [3090, 4096], 'whereas': [3091], 'circles)': [3099], 'fact': [3110], 'measures': [3113], 'same': [3119, 3958, 4071, 4092], 'course': [3121, 3806, 3948], 'suggests': [3122, 3614], 'processes': [3129], 'independent.': [3131], 'support': [3134, 3656], 'conclusion,': [3137], 'none': [3138], 'pharmacological': [3141], 'treatments': [3142], 'below': [3144, 3247, 3274, 3613], 'affected': [3145], 'inactivation.[Ca2+]i': [3147], 'measurements': [3150], 'combined': [3152], 'indo-1-loaded': [3154], 'examine': [3157], 'When': [3164], 'depleted': [3165, 3759], '[EGTA]i(1.2': [3170], 'mM)': [3171], 'Cao2+,': [3177, 3430, 3699], 'remained': [3179], 'constant': [3181], '~10': [3183], 'climbing': [3186], 'micromolar': [3188], 'levels,': [3189], 'would': [3191, 3780], 'via': [3197], 'eventually': [3200], 'overcome': [3201], 'capacity': [3203], 'buffer': [3207], '2A).': [3210], 'associated': [3216, 3343], 'progressive': [3219], 'period': [3225, 3524, 3960], '~100': [3227], 'declined,': [3232], 'reached': [3234, 3421], 'decreased,': [3238], 'presumably': [3239], 'fell': [3246], 'efflux': [3251], 'Ca2+-ATPases': [3253, 3823], 'membrane.': [3257], 'Increasing': [3258], 'buffering': [3260, 3299, 3399], 'power': [3261], 'restricted': [3270], 'levels': [3273], 'nM': [3276], '2B).': [3292], 'prolong': [3301], 'summarized': [3305, 4082], '10-17': [3307, 3447], '2C.': [3311], 'demonstrate': [3314, 3664, 3967], 'Cai2+-dependent.Figure': [3319], '2:Slow': [3320], 'Ca2+-dependent.': [3325], 'induction': [3335], 'decline': [3339, 4149], 'delayed': [3346], 'fall': [3349], '[Ca2+].': [3351], 'suppresses': [3360], 'increase,': [3363], 'more': [3367], 'sustained.': [3368], 'figures': [3376], '1B.': [3393], 'effect': [3396, 4093, 4213], 'like': [3407, 4232], 'those': [3408, 4233], 'Current': [3413], 'amplitude': [3414, 3420], 'plotted': [3434], 'point': [3437], 'onward.': [3438], 'Plotted': [3439], 'values': [3440, 4370], 'cells.View': [3448], '(PPT)During': [3456], 'recording,': [3459], 'soluble': [3460], 'components': [3461], 'diffuse': [3462], 'out': [3463], 'cause': [3469], 'rundown': [3470, 3673], 'activity.': [3473], 'To': [3474, 3798], 'whether': [3476, 3489], 'due': [3482, 3624, 3670, 3731, 3989], 'washout': [3485, 3676, 3733], 'phenomenon,': [3486], 'can': [3491], 'reversed': [3493], 'removal': [3495, 3638], 'Inhibition': [3499], 'reach': [3512], 'steady': [3513], 'state;': [3514], 'point,': [3517], 'removed': [3520], 'variable': [3523, 3633], 'then': [3526, 3712], 'reapplied': [3527], 'measure': [3529], 'had': [3535, 4090], 'recovered.': [3536], 'depicted': [3540], '3,': [3543], '60-s': [3545], 'nearly': [3551], 'recovery': [3553, 3561, 3592, 3648], 'amplitude.': [3557, 3601], 'varied': [3562], 'among': [3563], 'tested.': [3566], 'six': [3568], '11': [3580], '3%,': [3582], 'incubation': [3584], '100-150': [3589], '54': [3594], '14%': [3596], 'source': [3603], 'variation': [3606], 'known.': [3609], 'evidence': [3611], 'most': [3616], 'reuptake': [3626], 'stores;': [3630], 'thus,': [3631], 'degree': [3634], 'reemptying': [3636], 'contribute': [3642], 'amounts': [3646], 'observed.': [3651], 'Regardless,': [3652], 'simply': [3669], 'nonspecific': [3672], 'maintenance': [3682], 'ICRAC.Figure': [3684], '3:Slow': [3685], 'reversible.': [3688], 'bathed': [3703], '60': [3709], 'reexposed': [3713], 'recovered': [3723], 'almost': [3724], 'completely,': [3725], 'factor.View': [3737], '(PPT)Refilling': [3745], 'Ca2+Stores': [3747], 'Contributes': [3748], 'InactivationIn': [3751], 'above,': [3755], 'passively,': [3760], 'increasing': [3762], 'endoplasmic': [3767, 3826], 'reticulum': [3768, 3827], 'inhibiting': [3773], 'Ca2+-ATPases.': [3775], 'conditions,': [3778], 'refill': [3784], 'efficiently': [3785], 'thereby': [3791], 'causing': [3792], 'hypothesis,': [3801], 'dose': [3815], 'TG': [3817, 3886, 3981, 3999, 4074, 4088, 4095, 4111, 4144, 4166, 4177, 4215], '(1': [3818], 'μM)': [3819], 'blocks': [3822, 4146], '(9Premack': [3828], '25Lytton': [3856], 'Westlin': [3858], 'Hanley': [3860], 'M.R.': [3861], '1991;': [3865], '266:': [3866], '17067-17071Abstract': [3867], 'hence': [3875], 'prevents': [3876], 'reuptake.': [3878], 'incubated': [3881], 'EGTAi,': [3903], 'greatly': [3909], 'despite': [3911], 'large': [3913, 4036], '4A,': [3918, 3962], 'Table': [3919, 3963], '21': [3922], 'treated': [3924], 'TG,': [3926], '~50%': [3937], 'value': [3941], '4B).': [3943], 'Consistent': [3944], 'current,': [3951], 'only': [3954], 'partially': [3955, 4145], 'Ca2+-dependent': [3974, 4124], 'failure': [3979, 4109], 'hinder': [3984], 'inability': [3992], 'prevent': [3994, 4113], 'refilling.': [3996], 'repeated': [4001], '20': [4003, 4026, 4190], 'IP3': [4005, 4028, 4058, 4063, 4086, 4192], 'internal': [4008, 4195], 'attempt': [4011], 'overall': [4015], 'depletion.': [4019], 'release': [4021], 'stored': [4023], 'separate': [4032], 'spike': [4038], 'occurring': [4039, 4103, 4127], 'within': [4040], 'breaking': [4043], "Ringer's;": [4048], 'transients': [4050], '(data': [4059], 'shown).': [4061], 'alone': [4064, 4075], '(~50%;': [4076], 'n': [4077], 'cells).': [4080], '4B,': [4085], 'together': [4089], 'therefore': [4105, 4339], 'cannot': [4106], 'explain': [4107], 'Rather,': [4116], 'reveal': [4119], 'second': [4121], 'independently': [4128], 'content.Figure': [4134], '4:Store': [4135], 'EGTA.': [4165], '3-min': [4171], 'preincubation': [4172], "Ringer's.": [4175], 'limits': [4178], 'final': [4184], '~50%.': [4187], 'Addition': [4188], 'produces': [4197], 'effect,': [4200], 'incomplete': [4203], 'emptying': [4204], 'partial': [4212], 'inhibition.': [4218], '14-21': [4228], 'A.View': [4236], '(PPT)Effects': [4244], 'Phosphatase': [4246], 'Inhibitors': [4247], 'InactivationOkadaic': [4250], 'potent': [4253], 'inhibitor': [4254], '2A': [4259, 4365], '(26Nishiwaki': [4260], 'Fujiki': [4262], 'H.': [4263, 4267, 4326], 'Suganuma': [4264], 'Furuya-Suguri': [4266], 'Matsushima': [4268], 'Iida': [4270], 'Y.': [4271, 4298, 4378], 'Ojika': [4272], 'Yamada': [4274], 'K.': [4275, 4398], 'Uemura': [4276], 'D.': [4277], 'Yasumoto': [4278], 'Schmitz': [4280], 'Sugimura': [4282], 'Carcinogenesis.': [4284], '1837-1841Crossref': [4287], '(125)': [4290], '27Cohen': [4293], 'Holmes': [4295, 4375], 'C.F.B.': [4296, 4376], 'Tsukitani': [4297, 4377], '98-102Abstract': [4304, 4384], '(1256)': [4310, 4390], 'Xenopus': [4322], 'oocytes(28Parekh': [4323], 'A.B.': [4324], 'Terlau': [4325], 'Stühmer': [4327], 'W.': [4328], '814-818Crossref': [4332], '(319)': [4335], 'tested': [4340], 'acid': [4345, 4359], 'inhibitors': [4349], 'suppress': [4351], 'TG-insensitive': [4353], 'component': [4354], 'Okadaic': [4358], 'inhibits': [4360], 'vitro': [4367], 'IC50': [4369], '1-50': [4372], 'nM(27Cohen': [4373], '29Honkanen': [4393], 'R.E.': [4394], 'Codispoti': [4395], 'Tse': [4397], 'Boynton': [4399], 'A.L.': [4400], 'Toxicon.': [4401], '32:': [4403], '339-35': [4404]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1983672484', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-13T01:03:42.497574', 'created_date': '2016-06-24'}