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'critical': [54], 'steps': [55], 'regulation': [58], 'ligand-stimulated': [60], 'activities.': [62], 'One': [63], 'step': [64, 81], 'is': [65, 82], 'dimerization': [67, 107], '(through': [70], 'interaction': [72, 123], 'its': [74], 'N-termini': [75, 128], 'and': [76, 78, 126, 129, 140], 'C-termini),': [77], 'other': [80], 'activation': [84, 96, 156], 'N-terminal': [88], 'transactivation': [89, 134], 'domain': [90], '(NTD).': [91], 'increased': [93], 'NTD': [95], 'through': [100, 188], 'c-Src': [101, 139], 'kinase.': [102], 'also': [104], 'enhanced': [105], 'by': [108, 137], 'inhibiting': [109], 'glycogen': [110], 'synthase': [111], 'kinase-3β': [112], '(GSK-3β)': [113], 'activity,': [114], 'which': [115, 189], 'acts': [116], 'as': [117, 151], 'negative': [119], 'regulator': [120], 'C-termini.': [130], 'The': [131, 158], 'was': [135], 'abolished': [136], 'blocking': [138], 'activating': [141], 'GSK-3β': [142], 'kinases': [143, 149, 163, 187, 197], 'simultaneously,': [144], 'suggesting': 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