Publication Information

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3876, 3898, 3936, 3943, 3951, 3978, 4023, 4075, 4092, 4103, 4120, 4126, 4143, 4150, 4166, 4177, 4195, 4227, 4242, 4256, 4260, 4277, 4390, 4410, 4412, 4450, 4665, 4754, 4823, 4830, 4840, 4857, 4868, 4887, 4915, 4921, 5017, 5076, 5086, 5096, 5166, 5183, 5200, 5285, 5290, 5317, 5363, 5392, 5400, 5436, 5464, 5474, 5509, 5611, 5665, 5682, 5687, 5699, 5703, 5720, 5726, 5736, 5742, 5778, 5784, 5802], 'tyrosine': [6, 31, 50, 68, 170, 258, 283, 302, 320, 422, 885, 1012, 1015, 1034, 1166, 1223, 1638, 1666, 1743, 2722, 2748, 2775, 2796, 2823, 2846, 2863, 3256, 3272, 3471, 3971, 4021, 4030, 4042, 4066, 4081, 4109, 4131, 4838, 4873, 5235, 5500], 'phosphorylation': [7, 32, 69, 87, 152, 171, 201, 259, 284, 321, 339, 404, 423, 453, 2723, 2749, 2776, 2824, 2864, 2957, 2978, 3047, 3107, 3127, 3146, 3418, 3472, 3494, 3527, 3592, 3712, 3730, 3857, 3900, 4022, 4031, 4043, 4132, 4219, 4740, 4839, 4973, 5091, 5116, 5136], 'in': [8, 30, 46, 70, 85, 121, 222, 260, 282, 298, 322, 337, 373, 474, 569, 585, 771, 997, 1022, 1038, 1195, 1221, 1229, 1255, 1403, 1491, 1501, 1636, 1690, 1747, 1838, 1854, 1940, 1972, 2088, 2097, 2156, 2160, 2231, 2241, 2271, 2366, 2371, 2378, 2473, 2483, 2497, 2510, 2521, 2560, 2585, 2590, 2615, 2724, 2773, 2782, 2849, 2865, 2902, 2921, 2925, 2936, 2955, 2963, 3042, 3048, 3056, 3066, 3085, 3126, 3130, 3182, 3191, 3210, 3224, 3342, 3402, 3419, 3446, 3470, 3503, 3556, 3560, 3585, 3762, 3807, 3823, 3862, 3867, 3878, 3925, 3947, 3956, 3975, 3988, 4026, 4034, 4065, 4073, 4116, 4133, 4164, 4192, 4217, 4222, 4236, 4274, 4548, 4557, 4633, 4673, 4691, 4714, 4741, 4819, 4883, 4974, 5093, 5132, 5147, 5156, 5171, 5224, 5288, 5293, 5315, 5321, 5360, 5366, 5389, 5429, 5484, 5505, 5521, 5607, 5617, 5673, 5680, 5705, 5716, 5757], 'regulation': [9, 72, 261, 324, 541, 1024, 1040, 1749, 1839, 2783, 2904, 3086, 3809, 3977, 4074, 4165, 4176, 4194, 5289, 5316, 5391], 'calcium-dependent': [11, 263, 784, 865, 906, 1000, 1161, 1751, 5227, 5393, 5499, 5803], 'chloride': [12, 58, 211, 243, 264, 310, 463, 495, 552, 598, 626, 645, 839, 1152, 1752, 1781, 2169, 2786, 3089, 3981, 4104, 4197, 5029, 5201, 5211, 5223, 5394, 5722, 5749], 'secretion': [13, 265, 533, 553, 782, 819, 907, 1753, 1782, 2170, 4077, 4198, 5365, 5756], 'across': [14, 266, 534, 1754, 2805, 3011, 3164, 3785, 4199, 4999], 'T84': [15, 47, 267, 299, 1755, 1855, 1968, 2058, 2191, 2725, 2731, 2752, 2809, 2922, 3013, 3116, 3168, 3343, 3358, 3557, 3698, 3789, 3957, 4027, 4223, 4228, 4674, 4700, 4975, 5001, 5167, 5367, 5618, 5632], 'colonic': [16, 268, 1214, 1756, 1776, 2069, 3990, 5706], 'epithelial': [17, 269, 536, 563, 625, 752, 759, 766, 781, 809, 1026, 1151, 1165, 1262, 1757, 1777, 2923, 3812, 3958, 3980, 3991, 4108, 4167, 4201, 5193, 5707], 'cells.': [18, 48, 270, 300, 1758, 1856, 2726, 2810, 3014, 3959, 4028, 4202, 4693, 5368, 5487], 'The': [19, 49, 271, 301, 1396, 1528, 2108, 2225, 2360, 3478, 4354, 4430], 'calcium-mediated': [20, 272, 664, 763, 838, 1765, 3979, 4017, 4196], 'agonist': [21, 273, 5613], 'carbachol': [22, 274, 504, 671], '(CCh,': [23, 275], '100': [24, 276, 2257, 2606], 'μm)': [25, 277, 2741, 3465, 3613, 3704, 3853], 'stimulated': [26, 82, 169, 278, 334, 421, 2216, 2737, 2777, 3466, 3500, 3526, 3608, 3880, 4020], 'a': [27, 34, 64, 225, 279, 286, 316, 477, 1238, 1256, 1484, 1632, 1665, 1697, 1763, 1829, 2410, 2428, 2446, 2463, 2572, 2677, 2746, 2841, 2897, 2980, 3061, 3096, 3123, 3255, 3270, 3424, 3440, 3467, 3561, 3580, 3684, 3751, 3795, 3818, 3836, 3967, 4049, 4158, 4252, 4275, 4653, 4683, 4750, 4757, 4844, 5008, 5011, 5230, 5497, 5600, 5674, 5733, 5788], 'time-dependent': [28, 280, 3468], 'increase': [29, 84, 281, 336, 3469, 3502, 4064], 'range': [35, 287], 'proteins': [37, 289, 594, 1148, 2414, 2420, 2860, 3415, 3655, 4025, 4128, 4870], '(with': [38, 290], 'molecular': [39, 291, 1496, 2756, 2871, 2881, 3430, 4138], 'masses': [40, 292, 2757, 2872, 2882], 'ranging': [41, 293, 2758], 'up': [42, 294, 2759, 3227], 'to': [43, 61, 104, 123, 214, 246, 295, 313, 356, 375, 466, 498, 556, 650, 663, 762, 773, 835, 860, 864, 905, 999, 1006, 1018, 1219, 1243, 1425, 1463, 1481, 1519, 1562, 1626, 1660, 1737, 1779, 1827, 1844, 2062, 2081, 2139, 2162, 2205, 2644, 2695, 2706, 2714, 2760, 2803, 2834, 2867, 2879, 2895, 2927, 2945, 2971, 3009, 3017, 3044, 3074, 3112, 3132, 3162, 3175, 3228, 3337, 3367, 3388, 3392, 3421, 3428, 3486, 3564, 3640, 3749, 3769, 3783, 3816, 3859, 4052, 4060, 4070, 4101, 4114, 4135, 4141, 4156, 4234, 4250, 4270, 4420, 4442, 4453, 4553, 4559, 4670, 4681, 4709, 4743, 4848, 4864, 4912, 4986, 4997, 5049, 5052, 5065, 5120, 5158, 5173, 5196, 5216, 5226, 5353, 5374, 5386, 5622, 5713, 5792], '180': [44, 296, 2762], 'kDa)': [45, 297], 'kinase': [51, 94, 113, 130, 303, 346, 365, 382, 515, 518, 526, 853, 1013, 1167, 1224, 1639, 2797, 2847, 2934, 4067, 4082, 4110], 'inhibitor,': [52, 114, 304, 366, 2798, 3917, 4083, 4989], 'genistein': [53, 305, 1862, 2815], '(5': [54, 306, 2816], 'μm),': [55, 198, 307, 450, 2817, 3141], 'significantly': [56, 308, 2828, 3714, 3854, 4085, 4979], 'potentiated': [57, 108, 210, 309, 360, 462, 2829, 3157, 4086], 'secretory': [59, 75, 102, 212, 244, 311, 327, 354, 464, 496, 599, 646, 661, 685, 760, 862, 1027, 2855, 2907, 4057, 4122, 4244, 4401, 5030, 5723], 'responses': [60, 103, 213, 245, 312, 355, 465, 497, 649, 662, 761, 863, 2802, 2833, 3008, 3016, 3111, 3161, 3174, 3205, 3782, 3858, 4058, 4402, 4996], 'CCh,': [62, 314, 4019], 'indicating': [63, 315], 'for': [66, 318, 632, 1150, 1211, 1680, 1832, 1936, 2077, 2207, 2221, 2274, 2288, 2299, 2328, 2349, 2402, 2458, 2494, 2599, 2640, 2662, 2676, 2844, 2900, 3333, 3443, 3489, 3582, 3614, 3797, 3821, 3970, 4161, 4190, 4752, 4850, 5010, 5222, 5233, 5280, 5313, 5603, 5815], 'CCh-stimulated': [67, 74, 200, 319, 326, 452, 1841, 2785, 2821, 2845, 2854, 2906, 2953, 3001, 3079, 3088, 3144, 3693, 3716, 3728, 3811, 3844, 4056, 4076, 4121, 4243, 4381, 4400, 4971, 4981, 5012, 5028, 5084, 5134, 5181, 5364, 5379, 5604, 5663, 5721], 'negative': [71, 323, 747, 1023, 1748, 2903, 3808, 3976, 4193, 4422, 5390], 'responses.': [76, 328, 647, 2856, 2908, 3002, 4095, 4123, 4245, 5031, 5724], 'Further': [77, 329, 5152, 5349], 'studies': [78, 165, 330, 417, 1031, 1228, 1674, 2320, 3456, 3987, 4155, 4183, 5035, 5153, 5204, 5277, 5350, 5371, 5626], 'revealed': [79, 166, 331, 418, 2734], 'that': [80, 167, 218, 233, 332, 419, 470, 485, 595, 635, 746, 754, 779, 883, 902, 1033, 1160, 1245, 1676, 1689, 2309, 2917, 2952, 3055, 3078, 3207, 3462, 3487, 3550, 3565, 3912, 3932, 4014, 4053, 4209, 4356, 4371, 4398, 4663, 4849, 4920, 4965, 5059, 5078, 5462, 5493, 5631, 5639, 5695, 5710, 5747], 'CCh': [81, 105, 124, 168, 219, 247, 333, 357, 376, 420, 471, 499, 1212, 1761, 1849, 2719, 2739, 2779, 2804, 2835, 2868, 2928, 2974, 3010, 3018, 3133, 3163, 3176, 3372, 3407, 3422, 3451, 3463, 3490, 3498, 3551, 3611, 3709, 3758, 3784, 3827, 3896, 3952, 4106, 4136, 4213, 4357, 4391, 4687, 4824, 4836, 4854, 4998, 5108, 5696, 5730], 'an': [83, 237, 335, 489, 807, 2313, 2528, 3501, 4186, 4880, 5218, 5670], 'both': [86, 203, 338, 455, 615, 621, 1003, 1143, 3105, 3346, 3535, 3921, 4087, 4237, 4360], 'and': [88, 177, 185, 205, 232, 340, 429, 437, 457, 484, 546, 565, 580, 617, 777, 816, 849, 972, 1124, 1414, 1453, 1459, 1515, 1641, 1688, 1843, 1861, 1871, 1894, 1931, 2040, 2095, 2133, 2213, 2235, 2267, 2291, 2306, 2355, 2369, 2374, 2405, 2413, 2553, 2563, 2588, 2609, 2636, 2875, 2886, 3108, 3340, 3350, 3366, 3510, 3517, 3531, 3537, 3593, 3601, 3626, 3638, 3713, 4090, 4147, 4180, 4220, 4240, 4265, 4362, 4440, 4704, 4862, 5020, 5044, 5163, 5186, 5312, 5382, 5438, 5476, 5481, 5496, 5516, 5657, 5709, 5781, 5796], 'activity': [89, 341, 1168, 1225, 1853, 2568, 2848, 2965, 3955, 4068, 4111, 4221, 4690, 5381, 5515, 5684, 5728], 'extracellular': [92, 344, 513, 843, 953, 5401, 5666], 'signal-regulated': [93, 345, 514], '(ERK)': [95, 347], 'isoforms': [96, 348, 1525, 1835, 2888, 3935, 4149, 5702], 'mitogen-activated': [98, 111, 350, 363, 516], 'protein': [99, 112, 129, 351, 364, 381, 517, 525, 852, 2300, 2303, 2343, 2721, 2774, 2822, 3426], 'kinase.': [100, 352], 'Chloride': [101, 353, 532], 'were': [106, 358, 1863, 1874, 1898, 1910, 1920, 1927, 1932, 1942, 1970, 1987, 1999, 2045, 2075, 2086, 2137, 2198, 2214, 2238, 2278, 2297, 2322, 2346, 2362, 2375, 2400, 2406, 2415, 2421, 2491, 2524, 2550, 2582, 2596, 2622, 2638, 2693, 2704, 2912, 2958, 3019, 3177, 3457, 3607, 3629, 3646, 3656, 3872, 3923, 5036], 'also': [107, 154, 209, 359, 406, 461, 898, 3038, 3201, 3499, 3525, 3779, 4184, 4386, 4416, 4457, 4978, 5075, 5142], 'by': [109, 127, 143, 156, 241, 361, 379, 395, 408, 493, 542, 554, 812, 893, 1417, 1469, 1530, 1631, 1646, 1670, 1989, 2143, 2229, 2335, 2417, 2462, 2517, 2624, 2649, 2653, 2778, 2961, 2984, 3147, 3243, 3254, 3636, 3658, 3733, 3914, 4368, 4407, 4417, 4432, 4685, 4761, 5106, 5123, 5729], 'PD98059': [115, 367], '(20': [116, 368, 3140], 'μm).': [117, 150, 369, 402], 'Phosphorylation': [118, 370, 2646], 'ERK': [120, 151, 221, 372, 403, 473, 1524, 1534, 1628, 1662, 1681, 1834, 1852, 2567, 2901, 2918, 2948, 2956, 2964, 2977, 3040, 3046, 3080, 3100, 3106, 3129, 3145, 3249, 3334, 3360, 3409, 3453, 3493, 3583, 3694, 3717, 3729, 3760, 3773, 3829, 3845, 3856, 3899, 3954, 4145, 4191, 4218, 4272, 4393, 4436, 4555, 4671, 4689, 4702, 4712, 4739, 4826, 4851, 4982, 4988, 5022, 5090, 5110, 5115, 5135, 5169, 5188, 5314, 5380, 5482, 5514, 5615, 5683, 5701, 5727, 5785], 'response': [122, 374, 686, 998, 2161, 2866, 2926, 3043, 3131, 3420, 3483, 4134, 4558, 4742, 5172, 5225], 'was': [125, 140, 153, 377, 392, 405, 1884, 2114, 2227, 2294, 2358, 2443, 2515, 2542, 2569, 2651, 3051, 3423, 3484, 3731, 4032, 5128, 5141], 'mimicked': [126, 378], 'C': [131, 383, 527, 854], '(PKC)': [132, 384, 855], 'activator,': [133, 385], 'phorbol': [134, 386, 522, 3352], 'myristate': [135, 387, 523], 'acetate': [136, 388, 524], '(100': [137, 161, 389, 413, 2740, 2836, 3004, 3036, 3348, 3355, 3464, 3523, 3612, 3622], 'nm),': [138, 390, 3356], 'but': [139, 391, 1540, 4225, 4385, 4415, 4456, 4918, 4977, 5140, 5638, 5738], 'not': [141, 393, 1684, 3894, 4210, 4378, 4405, 4445, 4679, 4919, 4968, 5118, 5129, 5177, 5634], 'altered': [142, 394], 'PKC': [145, 397, 3822, 3840, 3937, 4666, 5124], 'inhibitor': [146, 191, 398, 443, 3098, 3686, 3774, 3838, 4255], 'GF': [147, 399, 1869, 4695, 5126], '109203X': [148, 400], '(1': [149, 197, 401, 449, 3703, 3852], 'induced': [155, 407, 3913], 'epidermal': [157, 409, 507, 894], 'growth': [158, 410, 508, 895, 1409, 1882, 4179, 4884], 'factor': [159, 411, 509, 896, 1883], '(EGF)': [160, 412, 897], 'ng/ml).': [162, 414], 'Immunoprecipitation/Western': [163, 415], 'blot': [164, 416, 2728, 2910, 3662], 'EGF': [174, 426, 510, 1420, 1650, 1892, 3347, 3521, 3621], 'receptor': [175, 427, 506, 884, 1210, 1421, 1468, 1560, 1893, 2997, 4375, 4451, 4872, 5046, 5068, 5511], '(EGFr)': [176, 428, 1422], 'increased': [178, 430, 2862, 3417, 3532, 4130], 'co-immunoprecipitation': [179, 431, 3504, 3533, 3595], 'adapter': [182, 434, 1456, 3507, 3598, 4859], 'proteins,': [183, 435, 2754, 3508, 3599, 4860], 'Shc': [184, 436, 1458, 3509, 3536, 3600, 4861, 5477], 'Grb2,': [186, 438, 1460, 3602, 4863], 'with': [187, 439, 1981, 2201, 2217, 2324, 2342, 2445, 2466, 2486, 2555, 2605, 2659, 2689, 2738, 2755, 2814, 3025, 3060, 3119, 3186, 3363, 3376, 3512, 3539, 3603, 3609, 3619, 3631, 3700, 3771, 3802, 3850, 3865, 3881, 3985, 4040, 4175, 4230, 4660, 4843, 4871, 5149, 5192, 5478, 5644, 5649, 5817], 'EGFr.': [189, 441, 3605, 4866, 5689, 5744], 'An': [190, 442], 'EGFr': [193, 204, 445, 456, 1450, 2327, 3434, 3445, 3474, 3513, 3530, 3541, 3555, 3591, 3688, 3711, 3747, 3916, 4842, 4923, 4972, 5019, 5043, 5185, 5287, 5471, 5646, 5780], 'phosphorylation,': [194, 446, 3361, 5472], 'tyrphostin': [195, 447, 3690, 3701, 3726, 3777, 3918, 4966, 4992, 5081, 5150], 'AG1478': [196, 208, 448, 460, 3702, 3727, 3778, 3919, 4967, 4993, 5082], 'reversed': [199, 451, 2820], 'ERK.': [206, 458], 'Tyrphostin': [207, 459, 1867], 'CCh.': [215, 467, 3045, 3113, 4744, 5174, 5650], 'conclude': [217, 469], 'activates': [220, 472, 1493, 4359], 'T84cells': [223, 475, 1939, 2085, 2813, 3849], 'via': [224, 476, 783, 1664, 1769, 5685, 5732], 'mechanism': [226, 478, 600, 811, 1633, 4684, 5791], 'involving': [227, 479, 1634, 5015], 'transactivation': [228, 480, 1647, 3262, 3553, 3744, 3798, 4753, 5016, 5069, 5085, 5182, 5284, 5686, 5741, 5777], 'EGFr,': [231, 483, 3265, 3801, 4756, 4917, 5088, 5480], 'this': [234, 486, 4676, 4833, 5160, 5430, 5711], 'pathway': [235, 240, 487, 492, 1668, 1700, 3274, 4677, 4758, 5103, 5221, 5734], 'constitutes': [236, 488], 'inhibitory': [238, 490, 803, 904, 5234], 'signaling': [239, 491, 887, 1192, 1253, 1398, 1745, 3973, 4364, 4423, 5013, 5675], 'which': [242, 494, 813, 833, 1145, 1418, 1461, 1490, 1531, 1550, 1642, 1767, 2818, 2915, 2937, 3142, 3244, 3259, 3393, 3460, 4055, 4112, 4421, 4433, 4686, 4697, 4705, 4908, 5024, 5107, 5213, 5677, 5739], 'may': [248, 500, 805, 820, 1036, 1551, 1643, 1683, 1694, 3082, 3246, 3260, 5057, 5104, 5668, 5786], 'be': [249, 501, 821, 1007, 1217, 1552, 1644, 1685, 3083, 3338, 4071, 4251, 4443, 4668, 5050, 5121, 5217, 5387, 5623, 5714], 'negatively': [250, 502, 836, 5025], 'regulated.': [251, 503], 'G-protein-coupled': [505, 1203], 'receptor:': [511], 'ERK,': [512, 3806, 4427], 'short': [519], 'circuit': [520], 'current': [521, 1541, 2149], 'polyacrylamide': [528, 2411], 'gel': [529, 2381, 2412, 2633], 'electrophorsis': [530], '4-diphenylacetoxy-N-methylpiperidine.': [531], 'intestinal': [535, 657, 751, 1164, 1859, 4200, 5809], 'cells': [537, 564, 753, 767, 1263, 1778, 1969, 1998, 2044, 2059, 2237, 2924, 3031, 3050, 3058, 3068, 3169, 3184, 3193, 3344, 3699, 3790, 3863, 3879, 4229, 4635, 4716, 5040, 5295, 5323, 5524, 5619, 5633], 'is': [538, 1187, 1400, 1423, 2919, 2979, 3252, 3269, 3400, 3578, 3663, 4172, 4248, 4366, 4652, 4875, 5074, 5176, 5750], 'under': [539], 'close': [540], 'hormonal,': [543], 'neural,': [544], 'paracrine,': [545], 'endocrine': [547], 'factors.': [548], 'Such': [549], 'factors': [550], 'stimulate': [551, 642, 780, 1163, 1533, 1627, 1661, 1780, 3357, 4215, 4435], 'binding': [555, 1448], 'specific': [557, 2661, 2981, 3097, 3685, 4254], 'receptors': [558, 1204, 1623, 1656, 1774], 'on': [559, 1213, 1466, 1556, 1775, 2055, 2195, 2720, 2742, 3000, 3104, 3408, 3452, 3692, 3710, 3759, 3828, 3843, 3953, 4392, 4447, 4738, 4825, 5038, 5513, 5614], 'surface': [561], 'consequently': [566, 817], 'stimulating': [567, 624], 'elevations': [568], 'levels': [571, 587, 677, 5801], 'intracellular': [573, 589, 640, 679, 831, 900, 1222, 1637], 'second': [574], 'messengers,': [575], 'such': [576, 654, 666, 802, 889, 1196, 1206, 1411, 3576, 4425, 5396], 'as': [577, 655, 667, 890, 1207, 1412, 1762, 1943, 2012, 2557, 2672, 2699, 4426, 4878, 5229, 5397], 'cyclic': [578, 618, 651], 'nucleotides': [579, 619], 'calcium.': [581], 'In': [582, 1232, 1652, 1731, 1822, 2969, 3072, 3379, 3722, 3814, 3890, 3960, 3983, 5690], 'turn,': [583], 'increases': [584, 1635, 2772, 2954, 2962, 3594, 4216, 4235], 'messengers': [590, 641, 832], 'activate': [591, 899, 1250], 'transport': [593, 1147, 5194], 'comprise': [596], '(1Barrett': [601, 867], 'K.E.': [602, 732, 789, 868, 915, 932, 987, 1784, 1804, 4613, 5414, 5763], 'Am.': [603, 869, 916, 963, 1062, 1075, 1101, 1115, 1134, 1177, 1274, 1318, 1338, 1354, 2181, 4003, 4572, 4727, 5248, 5267], 'J.': [604, 693, 709, 733, 870, 917, 933, 964, 1063, 1076, 1102, 1116, 1135, 1178, 1275, 1290, 1311, 1317, 1319, 1339, 1351, 1355, 1380, 1437, 1715, 1791, 1812, 1956, 2025, 2182, 4004, 4287, 4313, 4531, 4573, 4588, 4614, 4643, 4728, 4896, 4934, 5249, 5268, 5303, 5339, 5415, 5539, 5570, 5589, 5652], 'Physiol.': [605, 871, 918, 965, 1064, 1077, 1103, 1117, 1136, 1179, 1276, 1320, 1340, 1356, 2183, 4005, 4574, 4729, 5250, 5269], '1997;': [606, 872, 1277, 1321, 1590, 1718, 3300, 4486, 4534, 4575, 4591, 4730, 4788, 4937, 5304, 5542], '272:': [607, 873, 1322, 1719, 4535, 4592, 4938, 5271, 5543], 'C1069-C1076Crossref': [608, 874], 'PubMed': [609, 718, 739, 875, 922, 944, 969, 992, 1068, 1121, 1140, 1183, 1301, 1391, 1441, 1579, 1593, 1616, 1726, 1798, 1817, 1962, 2031, 2187, 3289, 3303, 3326, 4009, 4298, 4324, 4349, 4475, 4489, 4512, 4542, 4599, 4625, 4647, 4777, 4791, 4814, 4900, 4945, 4958, 5254, 5307, 5344, 5421, 5454, 5550, 5575, 5594], 'Google': [610, 701, 719, 742, 876, 923, 947, 970, 995, 1069, 1081, 1107, 1122, 1141, 1184, 1280, 1304, 1324, 1344, 1360, 1394, 1444, 1582, 1596, 1619, 1729, 1801, 1820, 1965, 2034, 2188, 3292, 3306, 3329, 4010, 4301, 4327, 4352, 4478, 4492, 4515, 4545, 4578, 4602, 4628, 4650, 4733, 4780, 4794, 4817, 4903, 4948, 4961, 5255, 5273, 5310, 5347, 5424, 5457, 5553, 5578, 5597], 'Scholar).': [611, 743, 877, 948, 1395, 1445, 1620, 1730, 1821, 1966, 2035, 2189, 3330, 4353, 4546, 4904, 5274, 5348, 5425, 5598], 'However,': [612, 1198, 1672, 4547], 'even': [613, 675, 5079], 'though': [614, 676, 4657, 5080], 'calcium': [616, 680, 954, 5402, 5465, 5468, 5494, 5605, 5667], 'are': [620, 659, 673, 768, 903, 1146, 1536, 1658, 2060, 2164, 2670, 2780, 3945, 4403, 4428, 4438, 5047, 5063, 5154, 5214, 5351, 5358, 5372, 5432, 5503, 5805], 'capable': [622], 'secretion,': [627, 1842, 2787, 3090, 4105, 5395], 'it': [628, 1155, 3906, 4396, 5489], 'has': [629, 687, 828, 1156, 1236, 4266, 4706, 5490, 5620], 'been': [630, 858, 1004, 1157, 1237, 1429, 3241, 4267, 4707, 4910, 5491], 'known': [631, 1189, 2061, 5048, 5179], 'many': [633, 1246, 3586], 'years': [634], 'these': [636, 1677, 2153, 3398, 3547, 4162, 4692, 4869], 'two': [637, 1547, 1678, 3238, 4125], 'classes': [638], 'temporally': [643], 'distinctive': [644], 'While': [648], 'nucleotide-mediated': [652], 'agonists,': [653, 665], 'vasoactive': [656, 1858], 'peptide,': [658], 'sustained,': [660], 'muscarinic': [669, 1209, 1773, 2995, 4373, 5282], 'agonist,': [670], '(CCh),1': [672], 'transient,': [674], 'remain': [681], 'elevated': [682, 5806], 'after': [683, 3231, 4045], 'resolved': [688], '(2Dharmsathaphorn': [689], 'K.': [690, 706, 1347, 1371, 1808, 1955, 2024, 2180, 5241, 5658], 'Pandol': [691, 729, 5411], 'S.J.': [692, 730, 928, 4334, 5412], 'Clin.': [694, 734, 1957, 2026, 5416], 'Invest.': [695, 735, 1958, 2027, 5417], '1985;': [696, 1959, 2028], '77:': [697], '348-354Crossref': [698], 'Scopus': [699, 740, 945, 993, 1302, 1392, 1442, 1580, 1594, 1617, 1727, 1799, 1818, 1963, 2032, 3290, 3304, 3327, 4299, 4325, 4350, 4476, 4490, 4513, 4543, 4600, 4626, 4648, 4778, 4792, 4815, 4901, 4946, 4959, 5308, 5345, 5422, 5455, 5551, 5576, 5595], '(238)': [700], 'Scholar,': [702, 720, 924, 1070, 1082, 1108, 1281, 1305, 1325, 1345, 1361, 1583, 1597, 1802, 3293, 3307, 4302, 4328, 4479, 4493, 4516, 4579, 4603, 4781, 4795, 4949, 5256, 5554, 5579], '3Mandel': [703], 'K.G.': [704, 2172], 'Dharmsathaphorn': [705, 1954, 2023, 2179], 'McRoberts': [707, 790, 1952, 2021, 2173, 5764], 'J.A.': [708, 791, 1273, 1953, 2022, 2174, 4571, 4726, 5765], 'Biol.': [710, 934, 1291, 1381, 1716, 4288, 4314, 4532, 4589, 4615, 4935, 5540], 'Chem.': [711, 935, 1292, 1382, 1717, 4289, 4315, 4533, 4590, 4616, 4936, 5541], '1986;': [712, 2184], '261:': [713], '704-712Abstract': [714], 'Full': [715, 939, 941, 1296, 1298, 1386, 1388, 1721, 1723, 4293, 4295, 4319, 4321, 4537, 4539, 4594, 4596, 4620, 4622, 4940, 4942, 5545, 5547], 'Text': [716, 940, 942, 1297, 1299, 1387, 1389, 1722, 1724, 4294, 4296, 4320, 4322, 4538, 4540, 4595, 4597, 4621, 4623, 4941, 4943, 5546, 5548], 'PDF': [717, 943, 1300, 1390, 1725, 4297, 4323, 4541, 4598, 4624, 4944, 5549], '4Vajanaphanich': [721], 'M.': [722, 979, 981, 1100, 1789, 5404], 'Schultz': [723, 4640, 5405], 'C.': [724, 1269, 4567, 4722, 5406], 'Tsien': [725, 5407], 'R.Y.': [726, 5408], 'Traynor-Kaplan': [727, 912, 929, 984, 5409], 'A.E.': [728, 913, 930, 985, 5410], 'Barrett': [731, 788, 914, 931, 986, 5413, 5762], '1995;': [736, 966, 1065, 1078, 1104, 1180, 1438, 1814, 4006, 4316, 4346, 4897, 4955, 5341, 5418, 5572], '96:': [737, 5419], '386-393Crossref': [738, 5420], '(53)': [741, 5423], 'This': [744, 2514, 4063, 4203, 5056, 5112], 'implies': [745], 'signals': [748, 804, 5237, 5384], 'exist': [749, 5105], 'within': [750, 4037, 5807], 'limit,': [755], 'or': [756, 2503, 2684, 3220, 3618, 3652], '"switch': [757], 'off"': [758], 'agonists.': [764], 'Since': [765, 3411, 4124], 'continuously': [769], 'exposed,': [770], 'vivo,': [772], 'endogenously': [774], 'generated': [775], 'hormones': [776], 'neurotransmitters': [778], 'mechanisms': [785, 1416, 1529, 1847, 3239, 4431], '(5Kaunitz': [786, 5760], 'J.D.': [787, 5761], 'Yamada': [792, 5766], 'T.': [793, 983, 1337, 1367, 1377, 1567, 1602, 1706, 3277, 3312, 4463, 4498, 4522, 4765, 4800, 5530, 5767], 'Gastroenterology.': [794, 988, 5768], '2nd': [795, 5769], 'Ed.': [796, 5770], 'Lippencott,': [797, 5771], 'Philadelphia,': [798, 5772], 'PA1995:': [799, 5773], '326-361Google': [800, 5774], 'Scholar),': [801, 1142, 1185, 4011, 4629, 4651, 4734, 4818, 4962, 5311, 5775], 'represent': [806, 2707, 4682, 5669, 5787], 'intrinsic': [808], '"braking"': [810], 'excessive': [814, 5794], 'chloride,': [815], 'water,': [818], 'prevented.': [822], 'Previous': [823], 'work': [824], 'from': [825, 1227, 1865, 1876, 1886, 1900, 1912, 1922, 4206, 5627], 'our': [826, 4154, 4182, 4658, 4746, 5005, 5034, 5628], 'laboratory': [827, 5629], 'identified': [829], 'several': [830, 2751, 4024], 'appear': [834, 1017, 1625, 3336, 4441, 4680, 5119], 'influence': [837], 'secretion.': [840, 1153, 3813, 3982, 4168, 5202], 'Influx': [841], 'calcium,': [844], 'generation': [845], 'inositol': [847, 975], '(3,4,5,6)-tetrakisphosphate,': [848], 'activation': [850, 1427, 1482, 1505, 1535, 1629, 1682, 2985, 3041, 3081, 3335, 3584, 3718, 3761, 3804, 4171, 4273, 4437, 4556, 4632, 4672, 4713, 4886, 5170, 5189, 5483, 5512, 5616, 5698, 5783], 'all': [857], 'shown': [859, 882, 4268, 4708, 5694], 'inhibit': [861, 4271, 4710], 'agonists': [866, 1248, 2163, 2218], 'More': [878], 'recently': [879], 'we': [880, 1735, 1824, 2788, 2938, 2989, 3091, 3385, 3437, 3765, 3831, 3964, 4012, 4152, 4963, 5692], 'kinase-dependent': [886, 1744, 3257, 3972, 5236], 'pathways,': [888, 4414], 'those': [891, 3223, 3877, 4142], 'activated': [892, 1554], 'pathways': [901, 1193, 1549, 1679, 1746, 3332, 3399, 3974, 4365, 5195], '(6Uribe': [908], 'J.M.': [909, 926, 5333, 5564], 'Gelbmann': [910], 'C.M.': [911, 1285, 4282], '1996;': [919, 936, 1118, 1137, 1293, 1357, 1383, 1576, 3286, 4290, 4472, 4617, 4774, 5251, 5270, 5451, 5591], '271:': [920, 937, 1294, 1358, 1384, 4291, 4618, 5252], 'C914-C922Crossref': [921], '7Uribe': [925], 'Keely': [927], '26588-26595Abstract': [938], '(71)': [946], 'Furthermore,': [949, 2933, 3137, 3764, 4984], 'since': [950, 3345, 4078, 5125, 5748], 'influx': [951, 5399, 5463, 5495, 5606, 5664], '(8Bischof': [955, 1169, 3995], 'G.': [956, 1170, 2176, 3996, 4641, 4929, 5583], 'Beate': [957, 1171, 3997], 'I.': [958, 1172, 1335, 1365, 1373, 3998, 4933, 5258, 5581], 'Reenstra': [959, 1060, 1173, 3999], 'W.W.': [960, 1061, 1174, 4000, 5239], 'Machen': [961, 1058, 1113, 1132, 1175, 4001], 'T.E.': [962, 1059, 1114, 1133, 1176, 4002], '268:': [967, 1066, 1181, 4007], 'C154-C161Crossref': [968, 1182, 4008], 'Scholar)': [971, 996, 1123, 5458], 'stimulation': [973, 1010, 1521, 1850, 2929, 2975, 3065, 3491, 3897, 4102, 4411, 4561, 4664, 5648, 5681], '(3,4,5,6)-tetrakisphosphate': [976], 'production': [977], '(9Vajanaphanich': [978], 'Wasserman': [980], 'Buranawuti': [982], '1993;': [989, 4644], '104:': [990], 'A286Crossref': [991], '(323)': [994], 'secretagogues': [1001, 1162, 5804], 'demonstrated': [1005, 1158, 2951, 4911, 5461, 5492], 'dependent': [1008, 4444], 'upon': [1009, 4458, 5647], 'activity,': [1014, 1640, 3841], 'kinases': [1016, 1035, 4874], 'play': [1019], 'important': [1020, 5219, 5504], 'role(s)': [1021], 'processes.': [1028, 1197], 'Indeed,': [1029], 'recent': [1030, 1233, 1673, 5276, 5434], 'demonstrate': [1032, 5278], 'function': [1037, 4115, 5320], 'apical': [1042], 'cystic': [1043, 5206], 'fibrosis': [1044, 5207], 'transmembrane': [1045, 5208], 'conductance': [1046, 5209], 'regulator': [1047, 5210], 'Cl−': [1048], 'channels': [1049, 1127, 5292, 5469], '(10Illek': [1050], 'B.': [1051, 1096, 1110, 1129, 4583, 4605, 5337, 5568], 'Fischer': [1052, 1111, 1130], 'H.': [1053, 1112, 1131], 'Santos': [1054], 'G.F.': [1055], 'Widdicombe': [1056], 'J.H.': [1057], 'C886-C893Crossref': [1067], '11Lehrich': [1071], 'R.W.': [1072], 'Forrest': [1073], 'J.N.': [1074], '269:': [1079, 1105], 'F594-F600PubMed': [1080], '12Sears': [1083], 'C.L.': [1084], 'Firoozmand': [1085], 'F.': [1086, 5262], 'Mellander': [1087], 'A.': [1088, 1265, 1333, 1587, 1947, 2016, 3297, 4306, 4345, 4483, 4563, 4718, 4785, 4951, 4953, 5243, 5450], 'Chambers': [1089], 'F.G.': [1090], 'Eromar': [1091], 'I.G.': [1092], 'Bot': [1093], 'A.G.M.': [1094], 'Scholte': [1095], 'DeJonge': [1097], 'H.R.': [1098], 'Donowitz': [1099], 'C874-C882PubMed': [1106], '13Illek': [1109], '270:': [1119, 1138, 4317], 'C265-C275Crossref': [1120, 1139], 'basolateral': [1125, 2744, 3610, 3620, 5054], 'K+': [1126, 5291, 5318, 5518], '(13Illek': [1128], 'essential': [1149], 'Although': [1154, 4169, 5599], 'previously': [1159, 1945, 2014], 'there': [1186, 1235], 'little': [1188], 'involved': [1194, 1402, 2781, 3084, 3401, 3946, 4072, 5359, 5388, 5715], 'some': [1199, 1691], 'insight': [1200], 'into': [1201, 1696, 2281], 'how': [1202, 5180], '(GPCRs),': [1205], 'epithelia,': [1215], 'might': [1216, 5190], 'linked': [1218, 4669], 'alterations': [1220], 'comes': [1226], 'other': [1230, 1925, 3268, 3939, 4715, 4922, 5383], 'models.': [1231], 'years,': [1234], 'growing': [1239], 'body': [1240], 'evidence': [1242, 1542, 4831], 'suggest': [1244, 4098], 'GPCR': [1247, 5510], 'can': [1249, 4667], 'MAPK': [1252, 1397, 1426, 1512, 1837, 2041, 2591, 2650, 4170, 4262, 4889, 5704], 'cascade': [1254, 1399, 4890, 5676], 'variety': [1257, 4276], 'cell': [1259, 2192, 2732, 2753, 3117, 3359, 3587, 3627, 3992, 4178, 4459, 4550, 4701, 5002, 5168], 'types': [1260, 4551], 'including': [1261, 4630], '(14Dabrowski': [1264, 4562, 4717], 'Groblewski': [1266, 4564, 4719], 'G.E.': [1267, 4565, 4720], 'Schafer': [1268, 4566, 4721], 'Guan': [1270, 4568, 4723], 'K.-U.': [1271, 4569, 4724], 'Williams': [1272, 4570, 4725], '42:': [1278, 1614, 3324, 4510, 4576, 4731, 4812], 'C1472-C1479Crossref': [1279, 4577, 4732], '15Wilkie': [1282], 'N.': [1283, 4280, 4585], 'Morton': [1284, 4281], 'Ng': [1286, 4283], 'L.L.': [1287, 4284], 'Boarder': [1288, 4285], 'M.R.': [1289, 4286], '32447-32453Abstract': [1295, 4292], '(47)': [1303, 4300], '16Gerthoffer': [1306], 'W.T.': [1307], 'Yamboliev': [1308], 'I.A.': [1309], 'Pohl': [1310], 'Haynes': [1312], 'R.': [1313, 1369, 1433, 4892, 5327, 5558], 'Dang': [1314], 'S.': [1315, 1331, 4344, 4637, 5245, 5247, 5325, 5449, 5556, 5585, 5655], 'McHugh': [1316], 'L244-L252PubMed': [1323], '17Heasley': [1326], 'L.E.': [1327], 'Senkfor': [1328], 'S.I.': [1329], 'Winitz': [1330], 'Strasheim': [1332], 'Teitelbaum': [1334], 'Berl': [1336], '1994;': [1341], '267:': [1342, 4956], 'F366-F373PubMed': [1343], '18Nakamura': [1346], 'Zhou': [1348], 'C.-J.': [1349], 'Parente': [1350], 'Chew': [1352], 'C.S.': [1353], 'G640-G649PubMed': [1359], '19Zou': [1362], 'Y.': [1363, 1375, 1379, 1708, 4524, 5532], 'Komuro': [1364], 'Yamazaki': [1366], 'Aikawa': [1368], 'Sumiyo': [1370], 'Shiojima': [1372], 'Hiroi': [1374], 'Mizuno': [1376], 'Yazaki': [1378], '33592-33597Abstract': [1385], '(192)': [1393], 'classically': [1401, 4173], 'mediating': [1404, 3403, 3447, 3948, 4820, 5506, 5608], 'mitogenic': [1406], 'actions': [1407], 'factors,': [1410], 'EGF,': [1413, 3567], 'coupled': [1424, 1771], 'well': [1430, 1538, 4876], 'elucidated': [1431], '(20Seger': [1432, 4891], 'Krebs': [1434, 4893], 'E.G.': [1435, 4894, 5301], 'FASEB': [1436, 4895], '9:': [1439, 1591, 3301, 4487, 4789, 4898], '726-735Crossref': [1440, 4899], '(3205)': [1443, 4902], 'Upon': [1446], 'ligand': [1447], 'becomes': [1451, 5642], 'autophosphorylated': [1452], 'recruits': [1454], 'molecules,': [1457], 'bind': [1462], 'tyrosine-phosphorylated': [1464], 'residues': [1465], 'virtue': [1470], 'their': [1472], 'SH2': [1473], 'domains.': [1474], 'Formation': [1475, 3574], 'EGFr-Shc-Grb2': [1478], 'complex': [1479, 4439], 'leads': [1480, 4233], 'guanine': [1485], 'nucleotide': [1486], 'exchange': [1487], 'factor,': [1488], 'mSOS,': [1489], 'turn': [1492, 1502], 'low': [1495], 'weight': [1497], 'G-protein,': [1498], 'p21ras.': [1499], 'This,': [1500], 'brings': [1503], 'about': [1504, 3248, 5198], 'upstream': [1508, 4258], 'components': [1509], 'cascade,': [1513, 4263], 'Raf': [1514], 'MEK,': [1516, 4264], 'ultimately': [1517, 5678], 'leading': [1518], 'MAPK.': [1527], 'GPCRs': [1532, 3245, 4434], 'less': [1537], 'understood': [1539], 'suggests': [1543], 'involvement': [1545, 1741], 'predominant': [1548, 5752], 'differentially': [1553], 'depending': [1555], 'nature': [1558, 4449], 'coupling': [1561, 4452], 'heterotrimeric': [1563, 4454], 'G-proteins': [1564], '(21van': [1565, 3275, 4461, 4763], 'Biesen': [1566, 1601, 1705, 3276, 3311, 4462, 4497, 4521, 4764, 4799, 5529], 'Luttrell': [1568, 1607, 1709, 1711, 3278, 3317, 4464, 4503, 4525, 4527, 4766, 4805, 5533, 5535], 'L.M.': [1569, 1599, 1712, 3279, 3309, 4465, 4495, 4528, 4767, 4797, 5536], 'Hawes': [1570, 1603, 3280, 3313, 4466, 4499, 4768, 4801], 'B.E.': [1571, 1604, 3281, 3314, 4467, 4500, 4769, 4802], 'Lefkowitz': [1572, 1609, 1713, 3282, 3319, 4468, 4505, 4529, 4770, 4807, 5537], 'R.J.': [1573, 1610, 1714, 3283, 3320, 4469, 4506, 4530, 4771, 4808, 5538], 'Endocr.': [1574, 3284, 4470, 4772], 'Rev.': [1575, 3285, 4471, 4773], '17:': [1577, 3287, 4473, 4775], '698-714Crossref': [1578, 3288, 4474, 4776], '(390)': [1581, 3291, 4477, 4779], '22Sugden': [1584, 3294, 4480, 4782], 'P.H.': [1585, 3295, 4481, 4783], 'Clerk': [1586, 3296, 4482, 4784], 'Cell': [1588, 3298, 4484, 4786], 'Signal.': [1589, 3299, 4485, 4787], '337-351Crossref': [1592, 3302, 4488, 4790], '(282)': [1595, 3305, 4491, 4793], '23Luttrell': [1598, 3308, 4494, 4796], 'van': [1600, 1704, 3310, 4496, 4520, 4798, 5528], 'Della-Rocca': [1605, 3315, 4501, 4803], 'G.J.': [1606, 1703, 3316, 4502, 4519, 4804, 5527], 'D.K.': [1608, 1710, 3318, 4504, 4526, 4806, 5534], 'Adv.': [1611, 3321, 4507, 4809], 'Pharmacol.': [1612, 1792, 1794, 1813, 3322, 4508, 4810], '1998;': [1613, 3323, 4509, 4811], '466-470Crossref': [1615, 3325, 4511, 4813], '(6)': [1618, 3328, 4514, 4816], 'Gi': [1621], 'protein-coupled': [1622, 1655], '(GiPCR)': [1624], 'predominantly': [1630, 1663], 'mediated': [1645, 1669, 2983, 3253, 5122], 'receptor.': [1651], 'contrast,': [1653, 3891], 'Gq': [1654], '(GqPCR)': [1657], 'believed': [1659, 5215, 5385], 'kinase-independent': [1667, 3273], 'PKC.': [1671], 'indicate': [1675, 4662, 5630], 'mutually': [1686], 'exclusive': [1687], 'systems': [1692, 4278], 'they': [1693], 'converge': [1695], 'common': [1698], 'p21ras-mediated': [1699], '(24Della': [1701, 5525], 'Rocca': [1702, 4518, 5526], 'Daaka': [1707, 4523, 5531], '19125-19132Abstract': [1720, 4536, 5544], '(414)': [1728, 4544, 5552], 'present': [1733, 3339, 3962], 'study': [1734, 3963], 'sought': [1736], 'elucidate': [1738], 'further': [1739], 'employed': [1760], 'prototypic': [1764, 4016], 'secretagogue,': [1766, 4018], 'acts': [1768], 'Gq-protein': [1770], 'M3': [1772, 2996, 4374], '(25Dickinson': [1783], 'Frizzell': [1785], 'R.A.': [1786, 4931], 'Chandra': [1787], 'Sekar': [1788], 'Eur.': [1790, 1811], 'Mol.': [1793], '1992;': [1795], '225:': [1796], '291-298Crossref': [1797], '(51)': [1800], "26O'Malley": [1803], 'Farrell': [1805], 'C.B.': [1806], "O'Boyle": [1807], 'Baird': [1809], 'A.W.': [1810], '275:': [1815], '83-89Crossref': [1816], '(55)': [1819], 'particular,': [1823], 'set': [1825, 2712, 3386], 'out': [1826, 2544, 2713, 3387, 3459], 'investigate': [1828, 2896, 3389, 4157], 'possible': [1830, 1846, 2842, 2898, 3441, 3819, 3968, 4159, 5231, 5376, 5601], 'determine': [1845, 2768, 2972, 3817, 5354], 'underlying': [1848], 'Carbachol,': [1857], 'polypeptide,': [1860], 'obtained': [1864, 1875, 1885, 1899, 1911, 1921, 1933], 'Sigma.': [1866], 'AG1478,': [1868, 3691], '902103X,': [1870, 4696], 'PD': [1872, 3102, 3120, 3138, 3199, 3211, 3775, 4231, 4246, 4990], '98059': [1873, 3121, 3139, 3200, 4232, 4247], 'Calbiochem,': [1877], 'San': [1878], 'Diego,': [1879], 'CA.': [1880], 'Epidermal': [1881], 'Genzyme,': [1887], 'Cambridge,': [1888], 'MA.': [1889], 'Mouse': [1890], 'anti-human': [1891, 2326], 'mouse': [1895, 2325], 'anti-phosphotyrosine': [1896], 'antibodies': [1897, 1909, 2660], 'Upstate': [1901], 'Biotechnology': [1902, 2453], 'Inc.,': [1903, 2436, 2454], 'Lake': [1904, 2455], 'Placid,': [1905, 2456], 'NY.': [1906], 'Rabbit': [1907], 'anti-phospho-ERK': [1908, 2556, 2943], 'New': [1913], 'England': [1914, 2578], 'Biolabs.': [1915], 'Tris': [1916], 'glycine': [1917], 'electrophoresis': [1918], 'gels': [1919], 'Bio-Rad.': [1923], 'All': [1924, 2668], 'reagents': [1926], 'analytical': [1929], 'grade': [1930], 'commercially.': [1934], 'Methods': [1935], 'maintenance': [1937], 'culture': [1941], 'described': [1944, 2013, 2558, 2657], '(27Weymer': [1946, 2015], 'Huott': [1948, 2017], 'P.': [1949, 2018, 4308, 5329, 5560], 'Liu': [1950, 2019], 'W.': [1951, 2020, 5297], '76:': [1960, 2029], '1828-1836Crossref': [1961, 2030], '(102)': [1964, 2033], 'Briefly,': [1967, 2580], 'grown': [1971, 2054, 2194], "Dulbecco's": [1973], 'modified': [1974], "Eagle's/F-12": [1975], 'media': [1976], '(JRH,': [1977], 'Lenexa,': [1978], 'KS)': [1979], 'supplemented': [1980], '5%': [1982, 2101], 'newborn': [1983], 'calf': [1984], 'serum.': [1985], 'Cells': [1986, 2071, 2277, 2549, 3606], 'passaged': [1988], 'trypsinization.': [1990], 'For': [1991, 2036, 2318], 'Ussing': [1992, 2089], 'chamber/voltage': [1993], 'clamp': [1994], 'experiments,': [1995], 'approximately': [1996, 2761, 4046], '106': [1997, 2043], 'seeded': [2000, 2046, 2072], 'onto': [2001, 2009, 2047, 2073, 2409, 2427], 'collagen-coated': [2002], 'polycarbonate': [2003, 2051, 2056], 'filters': [2004, 2057, 2074, 2197], '(Nuclepore,': [2005], 'Pleasanton,': [2006], 'CA)': [2007], 'glued': [2008], 'Lexan': [2010], 'rings,': [2011], 'Western': [2037, 2540, 2564, 2654, 2727, 2909, 3644], 'blotting': [2038, 2565, 2655], 'experiments': [2039, 2911, 3384], 'assays,': [2042, 2935], '30-mm': [2048], 'Millicell': [2049, 2196], 'transwell': [2050], 'filters.': [2052], 'When': [2053], 'retain': [2063], 'polarized': [2065, 5039], 'phenotype': [2066], 'native': [2068], 'epithelia.': [2070], 'cultured': [2076], '7–10': [2078], 'days': [2079], 'prior': [2080, 2643], 'use.': [2082], 'Monolayers': [2083, 2136], 'mounted': [2087], 'chambers': [2090], '(window': [2091], 'area': [2092], '=': [2093, 3033, 3070, 3152, 3195, 3738, 3885], '2cm2)': [2094], 'bathed': [2096], 'oxygenated': [2098], '(95%': [2099], 'O2,': [2100], 'CO2)': [2102], "Ringers'": [2103, 2112, 2202], 'solution': [2104, 2113, 2448], 'at': [2105, 2210, 2285, 2331, 2339, 2352, 2424, 2602, 3666, 4054, 4906], '37': [2106, 2211], '°C.': [2107], 'composition': [2109], '(in': [2115], 'mm):': [2116], '140': [2117], 'Na+,': [2118], '5.2': [2119], 'K+,': [2120], '1.2': [2121], 'Ca2+,': [2122], '0.8': [2123], 'Mg2+,': [2124], '120': [2125], 'Cl−,': [2126], '25': [2127], 'HCO3−,': [2128], '2.4': [2129], 'H2PO4−,': [2130], '0.4': [2131, 3026], 'HPO42−,': [2132], '10': [2134, 2289, 2481], 'glucose.': [2135], 'voltage-clamped': [2138, 2806, 3012, 3165, 3786, 5000], 'zero': [2140], 'potential': [2141, 3940], 'difference': [2142], 'continuous': [2145], 'application': [2146], 'short-circuit': [2148], '(I': [2150], 'sc).': [2151], 'Under': [2152], 'conditions,': [2154], 'changes': [2155], 'I': [2157, 2831, 3109, 3159, 3208, 4382], 'sc(ΔI': [2158], 'sc)': [2159], 'wholly': [2165], 'reflective': [2166], 'electrogenic': [2168], '(28Mandel': [2171], 'Beuerlein': [2175], 'Foster': [2177], 'E.S.': [2178], '250:': [2185], 'C486-C494Crossref': [2186], 'Polarized': [2190], 'monolayers': [2193, 2807, 3118, 3166, 3213, 3226, 3787], 'washed': [2199, 2364, 2583], '(twice)': [2200], 'solution,': [2203], 'allowed': [2204], 'equilibrate': [2206], '30': [2208, 2459, 2495, 2600, 2603], 'min': [2209, 2290, 2351, 2404, 2460, 2496, 2601, 2642, 3230], '°C,': [2212], 'then': [2215, 2239, 2279, 2347, 2363, 2376, 2407, 2492, 2525, 2597], '(±': [2219], 'antagonists)': [2220], 'times': [2223, 3616], 'indicated.': [2224], 'reaction': [2226], 'stopped': [2228, 2623], 'washing': [2230, 2478], 'ice-cold': [2232, 2242], 'phosphate-buffered': [2233, 2272, 2372], 'saline': [2234, 2373, 2485], 'lysed': [2240], 'lysis': [2243, 2367, 2586], 'buffer': [2244, 2368, 2383, 2451, 2587, 2635], '(1%': [2245], 'Triton': [2246], 'X-100,': [2247], '1': [2248, 2251, 2254, 2261, 2264, 2268, 2329, 2610, 3624, 4038, 4146], 'μg/ml': [2249, 2252, 2255, 2258], 'leupeptin,': [2250], 'pepstatin,': [2253], 'antipain,': [2256], 'phenylmethylsulfonyl': [2259], 'fluoride,': [2260, 2266], 'mm': [2262, 2269, 2385, 2392], 'Na+-vanadate,': [2263], 'mmsodium': [2265], 'EDTA': [2270], 'saline)': [2273], '45': [2275], 'min.': [2276], 'scraped': [2280], 'microcentrifuge': [2282], 'tubes,': [2283], 'spun': [2284], '12,000': [2286], 'rpm': [2287, 2354], 'pellet': [2293], 'discarded.': [2295, 2359], 'Samples': [2296, 2399], 'assayed': [2298], 'content': [2301], '(Bio-Rad': [2302], 'assay': [2304, 2575, 2592, 2619], 'kit)': [2305], 'adjusted': [2307], 'so': [2308, 3206], 'each': [2310], 'sample': [2311], 'contained': [2312], 'equal': [2314], 'amount': [2315], 'protein.': [2317], 'immunoprecipitation': [2319, 2562], 'lysates': [2321, 2733, 3628], 'incubated': [2323, 2493, 2598], 'h': [2330], '4': [2332, 2340, 2425, 3135, 3171], '°C': [2333, 2341, 2426, 2604], 'followed': [2334, 2461, 2516], 'another': [2336, 3989], '1-h': [2337, 2464], 'incubation': [2338, 2465], 'A-Sepharose.': [2344], 'Lysates': [2345], 'centrifuged': [2348], '3': [2350, 2403, 2641, 2931, 2967], '15,000': [2353], 'supernatant': [2357], 'pellets': [2361], 'twice': [2365, 2370, 2584, 2589], 'resuspended': [2377], '2': [2379, 2631, 4148], '×': [2380, 2480, 2632], 'loading': [2382, 2634], '(50': [2384], 'Tris,': [2386], 'pH': [2387], '6.8,': [2388], '2%': [2389], 'SDS,': [2390], '200': [2391], 'dithiothreitol,': [2393], '20%': [2394], 'glycerol,': [2395], '0.2%': [2396], 'bromphenol': [2397], 'blue).': [2398], 'boiled': [2401, 2639], 'loaded': [2408], 'separated': [2416], 'electrophoresis.': [2418], 'Resolved': [2419], 'transferred': [2422], 'overnight': [2423], 'polyvinylidene': [2429, 3641], 'difluoride': [2430, 3642], 'membrane': [2431, 2442], '(NEN': [2432], 'Life': [2433], 'Science': [2434], 'Products': [2435], 'Boston,': [2437], 'MA).': [2438], 'After': [2439, 2477, 3634], 'transfer': [2440, 3639], 'preblocked': [2444], '1%': [2447, 2474, 2487, 2511], 'blocking': [2450, 2475, 2512], '(Upstate': [2452], 'NY)': [2457], 'appropriate': [2468], 'concentration': [2469], 'primary': [2471], 'antibody': [2472, 2501], 'buffer.': [2476, 2513, 2593, 2620], '(3': [2479], 'min)': [2482, 3625], 'Tris-buffered': [2484], 'Tween': [2488], '(TBST),': [2489], 'membranes': [2490], 'horseradish': [2498], 'peroxidase-conjugated': [2499], 'secondary': [2500], '(anti-mouse': [2502], 'anti-rabbit': [2504], 'IgG;': [2505], 'Transduction': [2506], 'Laboratories,': [2507], 'Lexington,': [2508], 'KY)': [2509], 'three': [2518, 3668], '10-min': [2519], 'washes': [2520], 'TBST.': [2522], 'Proteins': [2523], 'detected': [2526, 3657], 'using': [2527, 2545, 2571], 'enhanced': [2529, 3659], 'chemiluminescence': [2530], 'detection': [2531], 'kit': [2532, 2576], '(Boehringer': [2533], 'Mannheim,': [2534], 'Indianapolis,': [2535], 'IN).': [2536], 'Densitometric': [2537], 'analysis': [2538, 2685, 2729], 'blots': [2541, 3645], 'carried': [2543, 3458], 'NIH': [2546], 'Image': [2547, 3671], 'software.': [2548], 'stimulated,': [2551], 'lysed,': [2552], 'immunoprecipitated': [2554, 3630], 'above': [2559, 3911], 'protocol.': [2566], 'determined': [2570, 2652, 4404], 'commercially': [2573], 'available': [2574], '(New': [2577], 'Biolabs).': [2579], 'immunoprecipates': [2581, 2595], 'Washed': [2594], 'μm': [2607], 'ATP': [2608], 'μg': [2611], 'Elk1': [2613, 2648], 'substrate': [2614], '50': [2616, 2628], 'μl': [2617, 2629], 'Reactions': [2621], 'addition': [2626, 3232], 'samples': [2637], 'SDS-PAGE.': [2645], '(as': [2656], 'above)': [2658], 'phosphorylated': [2664, 2920], 'form': [2665], 'Elk1.': [2667], 'data': [2669, 3548, 3930, 4097, 4659, 4747, 5006], 'expressed': [2671], 'mean': [2673, 2697], '±': [2674, 3021, 3027, 3053, 3063, 3149, 3179, 3188, 3735, 3874], 'S.E.': [2675], 'series': [2678, 3382], 'n': [2680], 'experiments.': [2681], "Student's": [2682], 'ttests': [2683], 'variance': [2687], '(ANOVA)': [2688], 'Student-Newman-Keuls': [2691], 'post-test': [2692], 'used': [2694, 3902, 3924, 5138, 5146], 'compare': [2696, 3375], 'values': [2698], 'appropriate.': [2700], 'pvalues': [2701], '<': [2702, 3155, 3197, 3218, 3741, 3888], '0.05': [2703], 'considered': [2705], 'significant': [2708, 3752, 5089], 'differences.': [2709], 'first': [2711, 2913, 3438], 'examine': [2715], 'effects': [2717, 2792, 3094, 3405, 3449, 3682, 3707, 3756, 3825, 3834, 3950, 4389, 4822, 5508, 5610], 'that,': [2735, 3767, 4099], 'when': [2736, 3901, 3920, 5137, 5145, 5799], 'domain,': [2745], 'rapid-onset': [2747], 'kDa,': [2763, 2877], 'occurred': [2764], '(Fig.': [2765, 2825, 2930, 2966, 3134, 3170, 3373, 3435, 3475, 3514, 3542, 3719, 3791, 3927], '1).': [2766], 'To': [2767, 3236], 'if': [2769, 2973, 3395, 5355], 'observed': [2771, 3488], 'next': [2789, 3381, 3679], 'general': [2795], 'genistein,': [2799, 4084], 'onI': [2800], 'sc': [2801, 2832, 3007, 3110, 3160, 3204, 3781, 4094, 4383, 4995], 'Pretreatment': [2811, 3114, 3696, 3847], 'partially': [2819], '2,': [2826], 'inset),': [2827], 'subsequent': [2830, 3158, 3803, 5021, 5187, 5517, 5782], 'μm;': [2837], 'Fig.': [2838, 3377, 3496], '2),': [2839], 'suggesting': [2840], 'limiting': [2850, 4117, 5717], 'extent': [2852, 3391, 4119, 4409, 4419, 5719], 'Two': [2857], 'showing': [2861], 'had': [2869, 4137, 4735], 'calculated': [2870], '44': [2874], '42': [2876], 'corresponding': [2878, 3427, 4051, 4140], 'ERK1': [2885], 'ERK2': [2887], 'MAPK,': [2890, 4151], 'respectively.': [2891], 'therefore': [2893], 'decided': [2894], 'conducted': [2914, 5037], 'verified': [2916, 3461], 'A).': [2932, 3136, 3477, 3721], 'measured': [2939], 'ability': [2941], 'immunoprecipitates': [2944], 'phosphorylate': [2946], 'substrate,': [2949], 'Elk,': [2950], 'closely': [2959], 'accompanied': [2960], 'B).': [2968, 3172], 'order': [2970, 3073, 3815, 5157], 'effect': [2982, 2992, 3910, 4737, 5144], 'cholinergic': [2987], 'receptors,': [2988], 'antagonist,': [2998, 4376, 5098], '4-DAMP,': [2999, 4377], '4-DAMP': [3003, 3035], 'nm)': [3005, 3037], 'abolishedI': [3006], 'Control': [3015], '21.5': [3020], '7.5': [3022], 'μA/cm2': [3023, 3181, 3190], 'compared': [3024, 3059, 3185], '0.2': [3028], 'μA/cm2in': [3029], '4-DAMP-pretreated': [3030, 3067], '(n': [3032, 3069, 3151, 3194, 3737, 3884], '4).': [3034], 'abolished': [3039, 3705, 4387, 5083], 'CCh-stimuated': [3049], '27.5': [3052], '8.2-fold': [3054], 'unstimulated': [3057], '1.4': [3062], '1.0-fold': [3064], '3).': [3071, 3378, 3497], 'test': [3075], 'hypothesis': [3077], 'activation,': [3101, 3689, 3830, 4703, 5023], '98059,': [3103, 3776, 4991], 'caused': [3122], 'concentration-dependent': [3124], 'reduction': [3125], 'reduced': [3143, 3732, 4980], '53.7': [3148], '19.9%': [3150], '3;': [3153, 3886], 'p': [3154, 3740, 3887], '0.05),': [3156], 'Maximal': [3173], '31.2': [3178], '5.3': [3180], 'control': [3183, 3225], '50.7': [3187], '7.4': [3189], 'PD90859-treated': [3192], '7;p': [3196], '0.05).': [3198, 3889], 'prolonged': [3202], 'CCh-stimulatedI': [3203, 4093], 'scvalues': [3209], '98059-treated': [3212], 'remained': [3214, 5092], 'signficantly': [3215], 'higher': [3216], '(p': [3217], '0.01': [3219], 'better)': [3221], 'than': [3222, 3370, 5101], '15': [3229], 'agonist.': [3235], 'date': [3237], 'proposed': [3242], 'bring': [3247, 5197], 'activation.': [3250, 3454, 4827, 4852, 5111], 'One': [3251], 'pathway,': [3258, 5014], 'involve': [3261], 'while': [3266], 'PKC-mediated': [3271, 4654], 'Both': [3331], 'functional': [3341], 'ng/ml)': [3349, 3524], 'ester,': [3353], 'PMA': [3354, 3866, 3882, 4661], 'albeit': [3362], 'different': [3364, 3368], 'kinetics': [3365], 'extents': [3369], 'does': [3371, 4212, 4678, 5117], '5,': [3374], 'either,': [3394], 'any,': [3396], 'activity.': [3410], 'one': [3412, 5102], 'displaying': [3416, 4129], '180-kDa': [3425], 'mass': [3431], '1),': [3436], 'Immunoprecipitation': [3455], '6': [3476], 'time': [3479, 4050, 4845], 'course': [3480, 4846], 'similar': [3485, 3563, 3768, 4847, 4985, 5356], '(cf.': [3495], 'Grb2': [3511, 3538, 5475], '6,': [3515, 3543], 'B': [3516], 'C).': [3518], 'As': [3519], 'expected,': [3520], 'itself': [3522], 'A-C).': [3544], 'Taken': [3545], 'together,': [3546], 'imply': [3549, 3931, 5058], 'stimulates': [3552, 3568, 3590, 4107, 4688, 4837, 4855, 5109, 5470, 5697], 'cells,': [3558, 4224, 4675, 4976, 5708], 'and,': [3559], 'fashion': [3562], 'formation': [3570], 'Shc-Grb2-EGFr': [3572], 'complexes.': [3573], 'complexes': [3577], 'normally': [3579, 4759], 'prerequisite': [3581], 'types.Figure': [3588], '6CCh': [3589], 'indicated': [3617], 'ng/ml;': [3623], 'anti-EGFr': [3632], 'antibodies.': [3633], 'separation': [3635], 'SDS-PAGE': [3637], 'membranes,': [3643], 'probed': [3647], 'with:': [3648], 'A,antiphosphotyrosine;': [3649], 'B,': [3650], 'anti-Shc;': [3651], 'C,anti-Grb2.': [3653], 'Immunoprecipitated': [3654], 'chemiluminescence.': [3660], 'Each': [3661], 'representative': [3664], 'least': [3667], 'experiments.View': [3669], 'Large': [3670], 'Figure': [3672], 'ViewerDownload': [3673], 'Hi-res': [3674], 'image': [3675], 'Download': [3676], '(PPT)': [3677], 'phosphorylation.': [3695, 3846, 4394, 4983], 'inhibited': [3715, 3855, 4380, 4698], '7': [3720, 3792], 'presence': [3724, 3869, 5095], '51.8': [3734], '4.0%': [3736], '7;': [3739], '0.01).': [3742], 'Thus,': [3743, 4395, 4694, 5004], 'appears': [3748, 4069, 4113, 4397, 5712], 'mediate': [3750, 5066], 'proportion': [3753], 'T84cells.': [3763], 'found': [3766, 4013, 4964], 'findings': [3770, 5435], 'potentiatedI': [3780, 4994], 'B),': [3793], 'supporting': [3794], 'cell-permeable': [3837], 'GF109203X,': [3842, 3944], 'GF109203X': [3851, 3871, 3892], 'PMA.': [3860], 'Responses': [3861], 'treated': [3864], '58.8': [3873], '5.0%': [3875], 'alone': [3883], 'did': [3893, 3905], 'alter': [3895], 'alone,': [3903, 5139], 'nor': [3904, 3938], 'any': [3908], 'additional': [3909, 5370], 'inhibitors': [3922], 'combination': [3926, 5148], '8).': [3928], 'These': [3929, 4096], 'neither': [3933], 'GF109203X-sensitive': [3934], 'nonspecific': [3941], 'targets': [3942], 'investigated': [3966], 'agreement': [3984], 'previous': [3986], 'line,': [3993], 'HT-29': [3994], 'Increased': [4029], 'rapid': [4033], 'onset,': [4035], 'occurring': [4036, 4044], 'min,': [4039, 4048], 'maximal': [4041], '5': [4047], 'return': [4059], 'basal': [4061], 'levels.': [4062], 'broad-spectrum': [4080], 'magnitude': [4089, 4239], 'duration': [4091, 4241], 'concommitant': [4100], 'weights': [4139], 'extended': [4153], 'enzymes': [4163], 'associated': [4174, 5643], 'differentiation,': [4181], 'reveal': [4185], 'apparent': [4187, 5161], 'acute': [4188], 'conclusion': [4204], 'stems': [4205], 'observations': [4208], 'only': [4211, 4379, 4406, 4446, 4969, 5130, 5635], 'rapidly': [4214], 'pretreatment': [4226], 'reported': [4249], 'highly': [4253], 'component': [4259], 'reliably': [4269], '(15Wilkie': [4279], '29Alessi': [4303], 'D.R.': [4304], 'Cuenda': [4305], 'Cohen': [4307], 'Dudley': [4309], 'D.T.': [4310, 4330], 'Salteil': [4311, 4337], 'A.R.': [4312, 4338], '27489-27494Abstract': [4318], '(3256)': [4326], '30Dudley': [4329], 'Pang': [4331], 'L.': [4332, 5654], 'Decker': [4333], 'Bridges': [4335], 'A.J.': [4336], 'Proc.': [4339, 5444], 'Natl.': [4340, 5445], 'Acad.': [4341, 5446], 'Sci.': [4342, 5447], 'U.': [4343, 5448], '92:': [4347], '7686-7689Crossref': [4348], '(2592)': [4351], 'idea': [4355], 'simultaneously': [4358], 'prosecretory': [4361, 4413], 'antisecretory': [4363], 'supported': [4367], 'finding': [4370], 'responses,': [4384], 'net': [4399], 'intermediates,': [4424], 'activated.': [4429], 'G-proteins,': [4455], 'type': [4460], '24Della': [4517], 'most': [4549], 'studied': [4552], 'date,': [4554], 'GqPCR': [4560], '31Liao': [4580], 'D.-F.': [4581], 'Monia': [4582], 'Dean': [4584], 'Berk': [4586], 'B.C.': [4587], '6146-6150Abstract': [4593], '(208)': [4601], '32Schieffer': [4604], 'Paxton': [4606], 'W.G.': [4607], 'Chai': [4608], 'Q.': [4609], 'Marrero': [4610], 'M.B.': [4611], 'Bernstein': [4612], '10329-10333Abstract': [4619], '(136)': [4627], 'M3receptor': [4631], 'neuroblastoma': [4634], '(33Offermans': [4636], 'Bombien': [4638], 'E.': [4639, 5331, 5562, 5659], 'Biochem.': [4642], '294:': [4645], '545-550Crossref': [4646], '(44)': [4649], 'process.': [4655], 'Even': [4656], 'PMA-stimulated': [4699], 'GqPCR-stimulated': [4711], 'no': [4736], 'Rather,': [4745], 'strongly': [4748], 'support': [4749, 4832, 5007], 'favored': [4760], 'Gi-PCR': [4762], 'Several': [4828], 'lines': [4829], 'hypothesis.': [4834], 'First,': [4835], 'Second,': [4853], 'recruitment': [4856], 'Association': [4867], 'documented': [4877], 'being': [4879], 'early': [4881, 5671], 'step': [4882, 5672], 'factor-mediated': [4885], 'Finally,': [4905], 'concentrations': [4907], 'block': [4913], 'autophosphorylation': [4914], 'family': [4924], 'members': [4925], '(34Gamett': [4926], 'D.C.': [4927], 'Pearson': [4928], 'Cerione': [4930], 'Friedberg': [4932], '12052-12056Abstract': [4939], '(99)': [4947], '35Levitzki': [4950], 'Gazit': [4952], 'Science.': [4954], '1782-1788Crossref': [4957], '(1620)': [4960], 'inhibtited': [4970], 'monolayers.': [5003], 'influences': [5026], 'simultaneous': [5027], 'Of': [5032, 5426], 'note,': [5033], 'where': [5041], 'M3muscarinic': [5045], 'localized': [5051], 'membrane.': [5055], 'particular': [5060, 5427], 'spatial': [5061], 'interrelationships': [5062], 'required': [5064, 5155, 5352, 5373], 'events': [5070], 'discussed': [5071], 'here.': [5072], 'It': [5073, 5175], 'note': [5077, 5428], 'implying': [5099], 'more': [5100], 'residual,': [5113], 'EGFr-independent': [5114, 5164], '902103X': [5127], 'ineffective': [5131], 'reducing': [5133], 'without': [5143], 'AG1478.': [5151], 'identify': [5159], 'PKC-': [5162], 'mode': [5165], 'yet': [5178, 5621], 'interact': [5191], 'inhibition': [5199, 5362, 5520], 'Some': [5203], 'implicate': [5205], 'channels,': [5212], 'exit': [5220], 'secretagogues,': [5228], 'target': [5232], '(36Reenstra': [5238], 'Yurko-Mauro': [5240], 'Dam': [5242], 'Raman': [5244], 'Shorten': [5246], 'C650-C657Crossref': [5253], '37Yang': [5257], 'Cheng': [5259], 'T.-H.': [5260], 'Wang': [5261], 'Price': [5263], 'E.M.': [5264], 'Hwang': [5265], 'T.-C.': [5266], 'C142-C155Crossref': [5272], 'Moreover,': [5275], 'roles': [5279], 'M1': [5281], 'receptor-mediated': [5283], 'kidney': [5294, 5523], '(38Tsai': [5296], 'Morielli': [5298], 'A.D.': [5299], 'Peralta': [5300], 'EMBO': [5302], '16:': [5305], '4597-4605Crossref': [5306], '(188)': [5309], 'channel': [5319, 5519], 'neuronal': [5322, 5486], '(39Lev': [5324], 'Martineez': [5326, 5557], 'Canoll': [5328, 5559], 'Pele': [5330, 5561], 'Musacchio': [5332, 5563], 'Plowman': [5334, 5565], 'G.D.': [5335, 5566], 'Rudy': [5336, 5567], 'Schlessinger': [5338, 5569, 5588], 'Nature.': [5340, 5571, 5590], '376:': [5342, 5573], '737-745Crossref': [5343, 5574], '(1253)': [5346, 5577], 'processes': [5357], 'ERK-mediated': [5361], 'Likewise,': [5369], 'define': [5375], 'interactions': [5377], 'between': [5378], 'agonist-stimulated': [5398, 5776], '(4Vajanaphanich': [5403], 'regard': [5431], 'Rosen': [5437], 'Greenberg': [5439, 5442], '(40Rosen': [5440], 'L.B.': [5441], 'M.E.': [5443], '93:': [5452], '1113-1118Crossref': [5453], '(172)': [5456], 'who': [5459], 'through': [5466], 'voltage-sensitive': [5467], 'association': [5473], 'PC12': [5485], 'Similarly,': [5488], 'novel': [5498], 'kinase,': [5501], 'PYK-2,': [5502, 5637], 'HEK-293': [5522], '39Lev': [5555], '41Dikic': [5580], 'Tokiwa': [5582], 'Lev': [5584], 'Countneidge': [5586], 'S.A.': [5587], '383:': [5592], '547-550Crossref': [5593], '(879)': [5596], 'investigated,': [5624], 'preliminary': [5625], 'express': [5636], 'enzyme': [5641], '2S.': [5651], 'Keely,': [5653], 'Bertelsen,': [5656], 'Barrett,': [5660], 'unpublished': [5661], 'observations.Thus,': [5662], 'results': [5679], 'summary,': [5691], 'Stimulation': [5725], 'occurs': [5731], 'independent': [5735], 'PKC,': [5737], 'involves': [5740], 'speculate': [5746], 'ion': [5753], 'driving': [5754], 'fluid': [5755, 5797], 'intestine': [5759], 'physiological': [5789], 'braking': [5790], 'prevent': [5793], 'electrolyte': [5795], 'loss': [5798], 'mucosa.': [5810], 'thank': [5812], 'Glenda': [5813], 'Wheeler': [5814], 'assistance': [5816], 'manuscript': [5818], 'submission.': [5819]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1983297072', 'counts_by_year': [{'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-14T06:52:28.786040', 'created_date': '2016-06-24'}