Title: α-Glucosidase Inhibitors for Patients With Type 2 Diabetes
Abstract: Hanefeld et al. (1) assert that the conclusion (“no evidence for an effect on mortality or morbidity”) from our systematic review on the effects of α-glucosidase inhibitors for patients with type 2 diabetes was biased. Furthermore, they claim to have found evidence for such an effect based on their own meta-analysis. We disagree with both statements.
First, we would like to underline that the solid basis of our results is a systematic review and that meta-analyses were only applied when this was methodologically sound. The extensive search for all possible trials investigating α-glucosidase inhibitor monotherapy …