Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1983186009', 'doi': 'https://doi.org/10.1007/bf00270982', 'title': 'Interleukin-6 (IL-6) and acute phase proteins in the disease course of patients with systemic lupus erythematosus', 'display_name': 'Interleukin-6 (IL-6) and acute phase proteins in the disease course of patients with systemic lupus erythematosus', 'publication_year': 1989, 'publication_date': '1989-03-01', 'ids': {'openalex': 'https://openalex.org/W1983186009', 'doi': 'https://doi.org/10.1007/bf00270982', 'mag': '1983186009', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2471249'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/bf00270982', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S50823678', 'display_name': 'Rheumatology International', 'issn_l': '0172-8172', 'issn': ['0172-8172', '1437-160X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5048733567', 'display_name': 'A. J. G. Swaak', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I907135538', 'display_name': 'Rotterdam University of Applied Sciences', 'ror': 'https://ror.org/0481e1q24', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I907135538']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'A. J. G. Swaak', 'raw_affiliation_strings': ['Department of Rheumatology, The Dr Daniel den Hoed Clinic, Groene Hilledijk 301, NL-3075 EA, Rotterdam, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Rheumatology, The Dr Daniel den Hoed Clinic, Groene Hilledijk 301, NL-3075 EA, Rotterdam, The Netherlands', 'institution_ids': ['https://openalex.org/I907135538']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088373381', 'display_name': 'Anthony van Rooyen', 'orcid': 'https://orcid.org/0000-0002-1221-7712'}, 'institutions': [{'id': 'https://openalex.org/I887064364', 'display_name': 'University of Amsterdam', 'ror': 'https://ror.org/04dkp9463', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I887064364']}, {'id': 'https://openalex.org/I4210093180', 'display_name': 'Dutch Blood Transfusion Society', 'ror': 'https://ror.org/00kan3777', 'country_code': 'NL', 'type': 'other', 'lineage': ['https://openalex.org/I4210093180']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'A. van Rooyen', 'raw_affiliation_strings': ['Department of Autoimmune Diseases, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, NL-1066 CX, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Autoimmune Diseases, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, NL-1066 CX, The Netherlands', 'institution_ids': ['https://openalex.org/I887064364', 'https://openalex.org/I4210093180']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058198903', 'display_name': 'Lucien A. Aarden', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I887064364', 'display_name': 'University of Amsterdam', 'ror': 'https://ror.org/04dkp9463', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I887064364']}, {'id': 'https://openalex.org/I4210093180', 'display_name': 'Dutch Blood Transfusion Society', 'ror': 'https://ror.org/00kan3777', 'country_code': 'NL', 'type': 'other', 'lineage': ['https://openalex.org/I4210093180']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'L. A. Aarden', 'raw_affiliation_strings': ['Department of Autoimmune Diseases, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, NL-1066 CX, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Autoimmune Diseases, Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, NL-1066 CX, The Netherlands', 'institution_ids': ['https://openalex.org/I887064364', 'https://openalex.org/I4210093180']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.457, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 49, 'citation_normalized_percentile': {'value': 0.908417, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '8', 'issue': '6', 'first_page': '263', 'last_page': '268'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11171', 'display_name': 'Genetics and Pathogenesis of Type 1 Diabetes', 'score': 0.989, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11171', 'display_name': 'Genetics and Pathogenesis of Type 1 Diabetes', 'score': 0.989, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus and Antiphospholipid Syndrome', 'score': 0.9852, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12286', 'display_name': 'Mechanosensitive Ion Channels in Physiology and Disease', 'score': 0.9743, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hla-genes', 'display_name': 'HLA Genes', 'score': 0.453897}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.90026605}, {'id': 'https://openalex.org/C198451711', 'wikidata': 'https://www.wikidata.org/wiki/Q327657', 'display_name': 'Rheumatology', 'level': 2, 'score': 0.8371416}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.5031375}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.49415043}, {'id': 'https://openalex.org/C2778674544', 'wikidata': 'https://www.wikidata.org/wiki/Q1414805', 'display_name': 'Systemic disease', 'level': 3, 'score': 0.48358577}, {'id': 'https://openalex.org/C57194454', 'wikidata': 'https://www.wikidata.org/wiki/Q424211', 'display_name': 'Acute-phase protein', 'level': 3, 'score': 0.48249578}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.46153295}, {'id': 'https://openalex.org/C2776912625', 'wikidata': 'https://www.wikidata.org/wiki/Q1485', 'display_name': 'Systemic lupus erythematosus', 'level': 3, 'score': 0.42861217}, {'id': 'https://openalex.org/C74172505', 'wikidata': 'https://www.wikidata.org/wiki/Q194908', 'display_name': 'Interleukin', 'level': 3, 'score': 0.42122373}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.216539}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.18883476}], 'mesh': [{'descriptor_ui': 'D007378', 'descriptor_name': 'Interleukins', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000209', 'descriptor_name': 'Acute-Phase Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000210', 'descriptor_name': 'Acute-Phase Reaction', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D000210', 'descriptor_name': 'Acute-Phase Reaction', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D000210', 'descriptor_name': 'Acute-Phase Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007378', 'descriptor_name': 'Interleukins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009961', 'descriptor_name': 'Orosomucoid', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D009961', 'descriptor_name': 'Orosomucoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000514', 'descriptor_name': 'alpha 1-Antichymotrypsin', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D000514', 'descriptor_name': 'alpha 1-Antichymotrypsin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000515', 'descriptor_name': 'alpha 1-Antitrypsin', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D000515', 'descriptor_name': 'alpha 1-Antitrypsin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/bf00270982', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S50823678', 'display_name': 'Rheumatology International', 'issn_l': '0172-8172', 'issn': ['0172-8172', '1437-160X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2471249', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.68}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1539584528', 'https://openalex.org/W1583209620', 'https://openalex.org/W1599290645', 'https://openalex.org/W1990223762', 'https://openalex.org/W1993799487', 'https://openalex.org/W1994092711', 'https://openalex.org/W2002076761', 'https://openalex.org/W2003363988', 'https://openalex.org/W2004650098', 'https://openalex.org/W2030070609', 'https://openalex.org/W2033496751', 'https://openalex.org/W2036452124', 'https://openalex.org/W2041551599', 'https://openalex.org/W2065588266', 'https://openalex.org/W2084386397', 'https://openalex.org/W2094989950', 'https://openalex.org/W2118764730', 'https://openalex.org/W2122248986', 'https://openalex.org/W2122462682', 'https://openalex.org/W2134180983', 'https://openalex.org/W2143037496', 'https://openalex.org/W2146203649', 'https://openalex.org/W2405400533', 'https://openalex.org/W4206163632', 'https://openalex.org/W42260490', 'https://openalex.org/W4236584263', 'https://openalex.org/W4241233276', 'https://openalex.org/W4297848098'], 'related_works': ['https://openalex.org/W2791912028', 'https://openalex.org/W2432792134', 'https://openalex.org/W2256634873', 'https://openalex.org/W2167937185', 'https://openalex.org/W2155470952', 'https://openalex.org/W2146501335', 'https://openalex.org/W2120603411', 'https://openalex.org/W2085524414', 'https://openalex.org/W2032533880', 'https://openalex.org/W133367683'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1983186009', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-08-26T14:55:47.996346', 'created_date': '2016-06-24'}