Title: A membrane protein in LRM55 glial cells cross-reacts with antibody to the anion exchange carrier of human erythrocytes
Abstract: Cl-/HCO3-exchange transport in the glial plasma membrane is remarkably similar to anion exchange transport in erythrocytes. When LRM55 cells were pretreated with the extracellular labeling reagent [125I]iodosulfanilic acid, radioactivity appeared primarily in two bands on denaturing polyacrylamide gels at Mr 70,000 and 30,000. Antibody to the human erythrocyte anion exchanger (Band 3) cross-reacted on immunoblots with an LRM55 band at Mr 68,000. The LRM55 Cl-/HCO3-exchanger may be a component of Mr 68,000 to 70,000.
Publication Year: 1986
Publication Date: 1986-06-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 9
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