Title: Hydroxy‐ and Carboxy‐Substituted Allylsilanes: A Simple and Stereoselective Method of Preparation
Abstract:Abstract When treated with two equivalents of a butyllithium/potassium tert ‐butoxide mixture, terminal olefins carrying unprotected hydroxy or carboxy groups generate allylmetal intermediates which c...Abstract When treated with two equivalents of a butyllithium/potassium tert ‐butoxide mixture, terminal olefins carrying unprotected hydroxy or carboxy groups generate allylmetal intermediates which can be trapped with chlorotrimethylsilane to afford functionalized (Z)‐2‐alkenyltrimethylsilanes. One equivalent of the superbasic reagent suffices if the unsaturated alcohols are first protected as acetals before being subjected to the metalation/silylation/hydrolysis sequence.Read More
Publication Year: 1997
Publication Date: 1997-03-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 15
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