Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1982366828', 'doi': 'https://doi.org/10.1177/197140090902200108', 'title': 'Perfusion MRI in the Evaluation of Cerebral Blood Volume and Mean Transit Time in Untreated and Recurrent Glioblastomas', 'display_name': 'Perfusion MRI in the Evaluation of Cerebral Blood Volume and Mean Transit Time in Untreated and Recurrent Glioblastomas', 'publication_year': 2009, 'publication_date': '2009-02-01', 'ids': {'openalex': 'https://openalex.org/W1982366828', 'doi': 'https://doi.org/10.1177/197140090902200108', 'mag': '1982366828', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24206953'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1177/197140090902200108', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191059882', 'display_name': 'The Neuroradiology Journal', 'issn_l': '1971-4009', 'issn': ['1971-4009', '2385-1996'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027754002', 'display_name': 'Massimo Principi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799399062', 'display_name': 'Santa Maria Nuova Hospital', 'ror': 'https://ror.org/053vhdz56', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799399062', 'https://openalex.org/I4210102885']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'M. Principi', 'raw_affiliation_strings': ['Department of Imaging Diagnostics, Neuroradiology Division, S. Maria Hospital; Terni, Italy', 'Terni, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Imaging Diagnostics, Neuroradiology Division, S. Maria Hospital; Terni, Italy', 'institution_ids': ['https://openalex.org/I2799399062']}, {'raw_affiliation_string': 'Terni, Italy', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002660199', 'display_name': 'M. Italiani', 'orcid': None}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'M. Italiani', 'raw_affiliation_strings': [' Terni, Italy - [email protected].'], 'affiliations': [{'raw_affiliation_string': ' Terni, Italy - [email protected].', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086816551', 'display_name': 'P. Ottaviano', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799399062', 'display_name': 'Santa Maria Nuova Hospital', 'ror': 'https://ror.org/053vhdz56', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799399062', 'https://openalex.org/I4210102885']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'P. Ottaviano', 'raw_affiliation_strings': ['Department of Imaging Diagnostics, Neuroradiology Division, S. Maria Hospital; Terni, Italy', 'Terni, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Imaging Diagnostics, Neuroradiology Division, S. Maria Hospital; Terni, Italy', 'institution_ids': ['https://openalex.org/I2799399062']}, {'raw_affiliation_string': 'Terni, Italy', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5027754002'], 'corresponding_institution_ids': ['https://openalex.org/I2799399062'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.54385, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 64, 'max': 71}, 'biblio': {'volume': '22', 'issue': '1', 'first_page': '48', 'last_page': '57'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11885', 'display_name': 'MRI in cancer diagnosis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11885', 'display_name': 'MRI in cancer diagnosis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10378', 'display_name': 'Advanced MRI Techniques and Applications', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cerebral-blood-volume', 'display_name': 'Cerebral blood volume', 'score': 0.7723815}, {'id': 'https://openalex.org/keywords/mean-transit-time', 'display_name': 'Mean transit time', 'score': 0.7455976}], 'concepts': [{'id': 'https://openalex.org/C2982720008', 'wikidata': 'https://www.wikidata.org/wiki/Q70680914', 'display_name': 'Cerebral blood volume', 'level': 3, 'score': 0.7723815}, {'id': 'https://openalex.org/C3019368741', 'wikidata': 'https://www.wikidata.org/wiki/Q653305', 'display_name': 'Mean transit time', 'level': 4, 'score': 0.7455976}, {'id': 'https://openalex.org/C146957229', 'wikidata': 'https://www.wikidata.org/wiki/Q1266915', 'display_name': 'Perfusion', 'level': 2, 'score': 0.74208015}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7362336}, {'id': 'https://openalex.org/C2776194525', 'wikidata': 'https://www.wikidata.org/wiki/Q282142', 'display_name': 'Glioblastoma', 'level': 2, 'score': 0.6790451}, {'id': 'https://openalex.org/C2989005', 'wikidata': 'https://www.wikidata.org/wiki/Q214963', 'display_name': 'Nuclear medicine', 'level': 1, 'score': 0.62676466}, {'id': 'https://openalex.org/C37557685', 'wikidata': 'https://www.wikidata.org/wiki/Q1896673', 'display_name': 'Blood volume', 'level': 2, 'score': 0.5732774}, {'id': 'https://openalex.org/C135691158', 'wikidata': 'https://www.wikidata.org/wiki/Q7168308', 'display_name': 'Perfusion scanning', 'level': 3, 'score': 0.50287145}, {'id': 'https://openalex.org/C143409427', 'wikidata': 'https://www.wikidata.org/wiki/Q161238', 'display_name': 'Magnetic resonance imaging', 'level': 2, 'score': 0.48736674}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.46554315}, {'id': 'https://openalex.org/C126838900', 'wikidata': 'https://www.wikidata.org/wiki/Q77604', 'display_name': 'Radiology', 'level': 1, 'score': 0.40344292}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19619709}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1177/197140090902200108', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191059882', 'display_name': 'The Neuroradiology Journal', 'issn_l': '1971-4009', 'issn': ['1971-4009', '2385-1996'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24206953', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.78}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W1897817370', 'https://openalex.org/W1944705852', 'https://openalex.org/W1951279288', 'https://openalex.org/W1964615535', 'https://openalex.org/W1972214151', 'https://openalex.org/W1973760073', 'https://openalex.org/W1974125693', 'https://openalex.org/W1974774291', 'https://openalex.org/W1978996858', 'https://openalex.org/W1981947689', 'https://openalex.org/W1987065233', 'https://openalex.org/W1989417969', 'https://openalex.org/W1993662624', 'https://openalex.org/W2000273913', 'https://openalex.org/W2004018486', 'https://openalex.org/W2013611417', 'https://openalex.org/W2015064457', 'https://openalex.org/W2017855653', 'https://openalex.org/W2022912277', 'https://openalex.org/W2026901966', 'https://openalex.org/W2038042304', 'https://openalex.org/W2046681082', 'https://openalex.org/W2056077646', 'https://openalex.org/W2057816945', 'https://openalex.org/W2061605350', 'https://openalex.org/W2072625840', 'https://openalex.org/W2073616825', 'https://openalex.org/W2096282669', 'https://openalex.org/W2097912113', 'https://openalex.org/W2101372259', 'https://openalex.org/W2106455035', 'https://openalex.org/W2116227981', 'https://openalex.org/W2118830476', 'https://openalex.org/W2120154261', 'https://openalex.org/W2121239587', 'https://openalex.org/W2121984545', 'https://openalex.org/W2131329324', 'https://openalex.org/W2133287601', 'https://openalex.org/W2133672120', 'https://openalex.org/W2134609589', 'https://openalex.org/W2158743409', 'https://openalex.org/W2162607416', 'https://openalex.org/W2165341811', 'https://openalex.org/W2168161253', 'https://openalex.org/W2169293905', 'https://openalex.org/W2169922321', 'https://openalex.org/W2184036762', 'https://openalex.org/W2402863076', 'https://openalex.org/W2556719987', 'https://openalex.org/W3142828467', 'https://openalex.org/W4256303532'], 'related_works': ['https://openalex.org/W3151810744', 'https://openalex.org/W2397048013', 'https://openalex.org/W2375678044', 'https://openalex.org/W2367716615', 'https://openalex.org/W2362707697', 'https://openalex.org/W2349454952', 'https://openalex.org/W2164643454', 'https://openalex.org/W2148731657', 'https://openalex.org/W1966772553', 'https://openalex.org/W1766011486'], 'abstract_inverted_index': {'Perfusion': [0, 151], 'MRI': [1, 152], 'by': [2, 153], 'means': [3, 154], 'of': [4, 13, 155, 199, 215], 'dynamic': [5, 156], 'contrast-enhanced': [6, 157], 'T2-weighted': [7, 158], 'MR': [8, 50, 159, 167], 'imaging': [9, 160, 168], 'allows': [10], 'quantitative': [11], 'analysis': [12], 'cerebral': [14, 220], 'blood': [15], 'volume': [16], '(CBV)': [17], 'and': [18, 64, 73, 82, 87, 92, 105, 119, 136, 176, 190, 206], 'mean': [19], 'transit': [20], 'time': [21], '(MTT)': [22], 'in': [23, 42, 54, 65, 103, 126, 129, 143, 148, 169, 218], 'intra-axial': [24], 'brain': [25], 'tumors.': [26, 150], 'Our': [27], 'aim': [28], 'was': [29, 77, 114], 'to': [30, 34, 165], 'compare': [31], 'recurrent': [32, 69, 130, 145, 177], 'glioblastomas': [33], 'untreated': [35, 127, 149, 175, 200], 'glioblastomas,': [36, 146], 'determining': [37], 'if': [38, 187], 'there': [39], 'are': [40, 195], 'differences': [41], 'perfusion': [43], 'parameters': [44], 'between': [45, 94, 110, 174], 'the': [46, 95, 111, 133, 144, 188], 'two': [47, 96, 112], 'groups.': [48, 97], 'Serial': [49], 'examinations': [51], 'were': [52, 90, 124, 141], 'performed': [53], '26': [55], 'patients': [56, 67], 'with': [57, 68], 'glioblastoma': [58, 70], 'histologically': [59], 'demonstrated': [60], 'before': [61], 'surgical': [62], 'resection': [63], '19': [66], 'after': [71], 'surgery': [72], 'radiotherapy.': [74], 'Tumor': [75], 'recurrence': [76, 182, 217], 'established': [78], 'using': [79], 'both': [80, 102], 'histological': [81], 'clinical': [83], 'criteria.': [84], 'Normalized': [85], 'CBV': [86, 108, 122, 193], 'MTT': [88, 139, 208], 'ratios': [89, 109, 123, 140, 194, 209], 'considered': [91, 212], 'compared': [93], 'A': [98], 'statistically': [99], 'significant': [100], 'difference,': [101], 'average': [104, 118, 135, 189, 205], 'maximum': [106, 120, 137, 191, 207], 'normalized': [107, 121, 138, 192], 'groups': [113], 'found.': [115], 'In': [116, 179, 202], 'particular,': [117, 180], 'greater': [125, 142], 'than': [128, 147], 'glioblastomas.': [131, 178, 201], 'On': [132], 'contrary,': [134], 'is': [161], 'a': [162], 'valuable': [163], 'adjunct': [164], 'conventional': [166], 'assessing': [170], 'different': [171], 'hemodynamic': [172], 'features': [173], 'tumor': [181], 'must': [183], 'be': [184, 211], 'suspected': [185], 'even': [186], 'far': [196], 'below': [197], 'those': [198], 'addition,': [203], 'increased': [204], 'could': [210], 'typical': [213], 'markers': [214], 'neoplastic': [216], 'irradiated': [219], 'tissue.': [221]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1982366828', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-08T17:58:32.977268', 'created_date': '2016-06-24'}