Publication Information

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'abstract_inverted_index': {'Indazole-': [0], 'and': [1, 10, 48, 82, 109, 132], 'indole-carboxamides': [2], 'were': [3, 35], 'discovered': [4], 'as': [5], 'highly': [6, 80], 'potent,': [7], 'selective,': [8], 'competitive,': [9], 'reversible': [11], 'inhibitors': [12, 85], 'of': [13, 62, 79], 'monoamine': [14], 'oxidase': [15], 'B': [16], '(MAO-B).': [17], 'The': [18, 31], 'compounds': [19], 'are': [20, 111], 'easily': [21], 'accessible': [22], 'by': [23], 'standard': [24], 'synthetic': [25], 'procedures': [26], 'with': [27, 66, 114, 127], 'high': [28, 107, 137], 'overall': [29], 'yields.': [30], 'most': [32], 'potent': [33, 81], 'derivatives': [34], 'N-(3,4-dichlorophenyl)-1-methyl-1H-indazole-5-carboxamide': [36], '(38a,': [37], 'PSB-1491,': [38], 'IC50': [39, 52, 99], 'human': [40, 53, 87, 100], 'MAO-B': [41, 54, 84, 88, 101], '0.386': [42], 'nM,': [43, 56, 90, 103], '>25000-fold': [44], 'selective': [45, 58, 83, 92], 'versus': [46, 59, 93, 105], 'MAO-A)': [47], 'N-(3,4-dichlorophenyl)-1H-indole-5-carboxamide': [49], '(53,': [50], 'PSB-1410,': [51], '0.227': [55], '>5700-fold': [57], 'MAO-A).': [60, 94], 'Replacement': [61], 'the': [63, 124, 128], 'carboxamide': [64], 'linker': [65], 'a': [67, 75, 133], 'methanimine': [68], 'spacer': [69], 'leading': [70], 'to': [71], '(E)-N-(3,4-dichlorophenyl)-1-(1H-indazol-5-yl)methanimine': [72], '(58)': [73], 'represents': [74], 'further': [76], 'novel': [77], 'class': [78], '(IC50': [86], '0.612': [89], '>16000-fold': [91], 'In': [95], 'N-(3,4-difluorophenyl-1H-indazole-5-carboxamide': [96], '(30,': [97], 'PSB-1434,': [98], '1.59': [102], 'selectivity': [104, 110], 'MAO-A>6000-fold),': [106], 'potency': [108, 138], 'optimally': [112], 'combined': [113], 'superior': [115], 'physicochemical': [116], 'properties.': [117], 'Computational': [118], 'docking': [119], 'studies': [120], 'provided': [121], 'insights': [122], 'into': [123], "inhibitors'": [125], 'interaction': [126], 'enzyme': [129], 'binding': [130], 'site': [131], 'rationale': [134], 'for': [135], 'their': [136, 140], 'despite': [139], 'small': [141], 'molecular': [142], 'size.': [143]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1981854138', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 7}], 'updated_date': '2024-12-25T06:10:48.672939', 'created_date': '2016-06-24'}