Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma

Name: Work Video:
Duration: 3 min 30 s
Ikuma Kasuga; Shigeru Makino; Hiroshi Kiyokawa; Harubumi Katoh; Yoshiro Ebihara; Kazuma Ohyashiki
{'id': 'https://openalex.org/W1981805100', 'doi': 'https://doi.org/10.1002/1097-0142(20011101)92:9<2399::aid-cncr1588>3.0.co;2-w', 'title': 'Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma', 'display_name': 'Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma', 'publication_year': 2001, 'publication_date': '2001-01-01', 'ids': {'openalex': 'https://openalex.org/W1981805100', 'doi': 'https://doi.org/10.1002/1097-0142(20011101)92:9<2399::aid-cncr1588>3.0.co;2-w', 'mag': '1981805100', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11745296'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/1097-0142(20011101)92:9<2399::aid-cncr1588>3.0.co;2-w', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2820011101%2992%3A9%3C2399%3A%3AAID-CNCR1588%3E3.0.CO%3B2-W', 'source': {'id': 'https://openalex.org/S126033908', 'display_name': 'Cancer', 'issn_l': '0008-543X', 'issn': ['0008-543X', '1045-7410', '1097-0142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2820011101%2992%3A9%3C2399%3A%3AAID-CNCR1588%3E3.0.CO%3B2-W', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5014368960', 'display_name': 'Ikuma Kasuga', 'orcid': 'https://orcid.org/0000-0002-3503-4660'}, 'institutions': [{'id': 'https://openalex.org/I158929114', 'display_name': 'Tokyo Medical University', 'ror': 'https://ror.org/00k5j5c86', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I158929114']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ikuma Kasuga', 'raw_affiliation_strings': ['First Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.'], 'affiliations': [{'raw_affiliation_string': 'First Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.', 'institution_ids': ['https://openalex.org/I158929114']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111993371', 'display_name': 'Shigeru Makino', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I158929114', 'display_name': 'Tokyo Medical University', 'ror': 'https://ror.org/00k5j5c86', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I158929114']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shigeru Makino', 'raw_affiliation_strings': ['First Dept of Internal Medicine, Tokyo Medical University, Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'First Dept of Internal Medicine, Tokyo Medical University, Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I158929114']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112069179', 'display_name': 'Hiroshi Kiyokawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I158929114', 'display_name': 'Tokyo Medical University', 'ror': 'https://ror.org/00k5j5c86', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I158929114']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Kiyokawa', 'raw_affiliation_strings': ['First Dept of Internal Medicine, Tokyo Medical University, Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'First Dept of Internal Medicine, Tokyo Medical University, Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I158929114']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024133837', 'display_name': 'Harubumi Katoh', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I158929114', 'display_name': 'Tokyo Medical University', 'ror': 'https://ror.org/00k5j5c86', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I158929114']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Harubumi Katoh', 'raw_affiliation_strings': ['#N#        First Department of Surgery, Tokyo Medical University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': '#N#        First Department of Surgery, Tokyo Medical University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I158929114']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111670069', 'display_name': 'Yoshiro Ebihara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I158929114', 'display_name': 'Tokyo Medical University', 'ror': 'https://ror.org/00k5j5c86', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I158929114']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshiro Ebihara', 'raw_affiliation_strings': ['Second Department of Pathology, Tokyo Medical University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Pathology, Tokyo Medical University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I158929114']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5053689963', 'display_name': 'Kazuma Ohyashiki', 'orcid': 'https://orcid.org/0000-0003-0845-5758'}, 'institutions': [{'id': 'https://openalex.org/I158929114', 'display_name': 'Tokyo Medical University', 'ror': 'https://ror.org/00k5j5c86', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I158929114']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuma Ohyashiki', 'raw_affiliation_strings': ['First Dept of Internal Medicine, Tokyo Medical University, Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'First Dept of Internal Medicine, Tokyo Medical University, Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I158929114']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4740, 'currency': 'USD', 'value_usd': 4740, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.756, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 221, 'citation_normalized_percentile': {'value': 0.921628, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '92', 'issue': '9', 'first_page': '2399', 'last_page': '2405'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10649', 'display_name': 'Multiple Myeloma Research and Treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10649', 'display_name': 'Multiple Myeloma Research and Treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/leukocytosis', 'display_name': 'Leukocytosis', 'score': 0.88526905}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.94511926}, {'id': 'https://openalex.org/C2778923028', 'wikidata': 'https://www.wikidata.org/wiki/Q974869', 'display_name': 'Leukocytosis', 'level': 2, 'score': 0.88526905}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.5769231}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.54523677}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.49624974}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.43581524}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.41547057}, {'id': 'https://openalex.org/C61434518', 'wikidata': 'https://www.wikidata.org/wiki/Q932510', 'display_name': 'General surgery', 'level': 1, 'score': 0.36649787}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.35038364}], 'mesh': [{'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D018288', 'descriptor_name': 'Carcinoma, Small Cell', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D007964', 'descriptor_name': 'Leukocytosis', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002289', 'descriptor_name': 'Carcinoma, Non-Small-Cell Lung', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D018288', 'descriptor_name': 'Carcinoma, Small Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018288', 'descriptor_name': 'Carcinoma, Small Cell', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016179', 'descriptor_name': 'Granulocyte Colony-Stimulating Factor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D016179', 'descriptor_name': 'Granulocyte Colony-Stimulating Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016179', 'descriptor_name': 'Granulocyte Colony-Stimulating Factor', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007124', 'descriptor_name': 'Immunoenzyme Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D007964', 'descriptor_name': 'Leukocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007964', 'descriptor_name': 'Leukocytosis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008175', 'descriptor_name': 'Lung Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/1097-0142(20011101)92:9<2399::aid-cncr1588>3.0.co;2-w', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2820011101%2992%3A9%3C2399%3A%3AAID-CNCR1588%3E3.0.CO%3B2-W', 'source': {'id': 'https://openalex.org/S126033908', 'display_name': 'Cancer', 'issn_l': '0008-543X', 'issn': ['0008-543X', '1045-7410', '1097-0142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11745296', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1002/1097-0142(20011101)92:9<2399::aid-cncr1588>3.0.co;2-w', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2820011101%2992%3A9%3C2399%3A%3AAID-CNCR1588%3E3.0.CO%3B2-W', 'source': {'id': 'https://openalex.org/S126033908', 'display_name': 'Cancer', 'issn_l': '0008-543X', 'issn': ['0008-543X', '1045-7410', '1097-0142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.58, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W116031897', 'https://openalex.org/W1538069960', 'https://openalex.org/W1578149674', 'https://openalex.org/W1967643308', 'https://openalex.org/W1970604883', 'https://openalex.org/W1975549289', 'https://openalex.org/W1976211354', 'https://openalex.org/W1995908571', 'https://openalex.org/W1996541415', 'https://openalex.org/W2000446337', 'https://openalex.org/W2005589673', 'https://openalex.org/W2008577338', 'https://openalex.org/W2035195844', 'https://openalex.org/W2064621194', 'https://openalex.org/W2067630479', 'https://openalex.org/W2076115419', 'https://openalex.org/W2092935813', 'https://openalex.org/W2126284570', 'https://openalex.org/W2126719713', 'https://openalex.org/W2280533608', 'https://openalex.org/W277141492', 'https://openalex.org/W28926443', 'https://openalex.org/W4245648471', 'https://openalex.org/W79221296'], 'related_works': ['https://openalex.org/W4249732185', 'https://openalex.org/W2599151900', 'https://openalex.org/W2393339768', 'https://openalex.org/W2391577190', 'https://openalex.org/W2081126084', 'https://openalex.org/W1999973083', 'https://openalex.org/W1996827561', 'https://openalex.org/W1972939890', 'https://openalex.org/W1558121951', 'https://openalex.org/W1515202398'], 'abstract_inverted_index': {'BACKGROUND': [0], 'Tumor-related': [1, 223], 'leukocytosis': [2, 224], 'is': [3, 8, 101, 240], 'a': [4, 59, 214], 'paraneoplastic': [5], 'syndrome': [6], 'that': [7, 197], 'encountered': [9], 'occasionally': [10], 'in': [11, 39, 103, 230, 257], 'the': [12, 45, 67, 88, 98, 219, 231], 'clinical': [13, 48, 232], 'course': [14, 233], 'of': [15, 23, 41, 50, 66, 234], 'patients': [16, 63, 73, 91, 109, 141, 148, 156, 205, 212, 258], 'with': [17, 64, 76, 83, 206, 218, 259], 'lung': [18, 68, 86, 95, 209, 235, 246, 260], 'carcinoma.': [19, 106, 210, 247, 261], 'Recently,': [20], 'autonomous': [21], 'production': [22, 227], 'hematopoietic': [24], 'cytokines': [25], '(granulocyte-colony': [26], 'stimulating': [27, 31], 'factor': [28, 32], '[G-CSF],': [29], 'granulocyte-macrophage–colony': [30], '[GM-CSF],': [33], 'and': [34, 47, 71, 97, 116, 122, 135, 154, 176, 193, 225, 237], 'interleukin-6': [35], '[IL-6])': [36], 'were': [37, 69, 74, 110, 128, 179, 198, 203], 'identified': [38], 'some': [40], 'these': [42], 'patients.': [43, 221], 'However,': [44], 'incidence': [46, 100], 'characterization': [49], 'this': [51, 238], 'phenomenon': [52, 239], 'have': [53], 'not': [54], 'been': [55], 'clarified.': [56], 'METHODS': [57], 'During': [58], '7-year': [60], 'period,': [61], '227': [62], 'carcinoma': [65], 'investigated,': [70], '33': [72, 108], 'diagnosed': [75], 'tumor-related': [77], 'leukocytosis.': [78], 'Except': [79], 'for': [80, 112, 130, 190, 200], 'one': [81, 186], 'patient': [82], 'small': [84], 'cell': [85, 94, 105, 208, 245], 'carcinoma,': [87, 96, 236], 'other': [89, 220], '32': [90], 'had': [92, 213], 'nonsmall': [93, 207, 244], 'highest': [99], 'recognized': [102], 'large': [104], 'These': [107, 211], 'examined': [111], 'serum': [113, 144, 151, 159], 'G-CSF,': [114], 'GM-CSF,': [115, 134], 'IL-6': [117, 160], 'levels': [118], 'using': [119], 'enzyme': [120], 'immunoassays': [121], 'enzyme-linked': [123], 'immunosorbent': [124], 'assays.': [125], 'Tumor': [126], 'specimens': [127, 163, 170, 178, 196], 'stained': [129, 164, 171, 180], 'antihuman': [131], 'cytokine': [132, 226], '(G-CSF,': [133], 'IL-6)': [136], 'monoclonal': [137, 201], 'antibodies.': [138], 'RESULTS': [139], 'Sixteen': [140], 'showed': [142, 149, 157], 'high': [143, 150, 158], 'G-CSF': [145, 192], 'levels,': [146, 153], '4': [147], 'GM-CSF': [152], '18': [155], 'levels.': [161], 'Twelve': [162], 'positively': [165, 172, 181], 'against': [166, 173, 182], 'anti-G-CSF': [167], 'antibody.': [168], 'Two': [169], 'anti-GM-CSF': [174], 'antibody,': [175, 184], 'three': [177], 'anti-IL-6': [183], 'including': [185], 'double': [187], 'positive': [188, 199], 'specimen': [189], 'both': [191], 'IL-6.': [194], 'All': [195], 'antibodies': [202], 'from': [204], 'poor': [215], 'outcome': [216], 'compared': [217], 'CONCLUSIONS': [222], 'frequently': [228], 'occur': [229], 'related': [241], 'mainly': [242], 'to': [243, 251], 'Its': [248], 'occurrence': [249], 'appears': [250], 'be': [252], 'an': [253], 'ominous': [254], 'prognostic': [255], 'sign': [256], 'Cancer': [262, 267], '2001;92:2399–405.': [263], '©': [264], '2001': [265], 'American': [266], 'Society.': [268]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1981805100', 'counts_by_year': [{'year': 2024, 'cited_by_count': 14}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 16}, {'year': 2021, 'cited_by_count': 16}, {'year': 2020, 'cited_by_count': 20}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 12}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 11}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 11}], 'updated_date': '2025-01-09T17:18:52.625217', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
