Publication Information

{'id': 'https://openalex.org/W1981111315', 'doi': 'https://doi.org/10.1111/j.1600-0625.2005.0355g.x', 'title': 'Biological effects of UV radiation on keratinocytes and Langerhans cells', 'display_name': 'Biological effects of UV radiation on keratinocytes and Langerhans cells', 'publication_year': 2005, 'publication_date': '2005-09-19', 'ids': {'openalex': 'https://openalex.org/W1981111315', 'doi': 'https://doi.org/10.1111/j.1600-0625.2005.0355g.x', 'mag': '1981111315', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16176292'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1600-0625.2005.0355g.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1600-0625.2005.0355g.x', 'source': {'id': 'https://openalex.org/S158010168', 'display_name': 'Experimental Dermatology', 'issn_l': '0906-6705', 'issn': ['0906-6705', '1600-0625'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 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1167, 1233, 1255, 1262, 1269], 'middle': [6], 'wavelength': [7], 'range,': [8], 'exerts': [9], 'various': [10], 'biological': [11, 195], 'effects.': [12], 'These': [13, 103, 431, 1275], 'include': [14, 432], 'induction': [16, 71, 298, 337, 445, 858, 892, 1065, 1095, 1160], 'of': [17, 21, 26, 39, 47, 72, 83, 98, 110, 144, 161, 188, 217, 247, 253, 264, 273, 299, 338, 344, 437, 446, 478, 536, 552, 607, 624, 712, 728, 752, 786, 794, 800, 805, 811, 818, 835, 866, 898, 920, 925, 1018, 1066, 1079, 1149, 1161, 1212, 1235, 1257, 1271, 1297], 'apoptosis': [18, 49, 213, 300, 401, 421, 458, 521, 592, 634, 727, 1040, 1088, 1126, 1146], 'and': [19, 50, 290, 393, 405, 425, 444, 570, 735, 937, 972, 1098, 1127, 1288, 1295], 'suppression': [20], 'immune': [23, 681, 1286], 'system.': [24, 81, 688, 709, 1073], 'Induction': [25, 82], 'DNA': [27, 40, 68, 79, 84, 122, 340, 388, 434, 1043, 1061, 1096, 1128, 1150, 1178, 1221, 1248, 1293], 'damage': [28, 41, 69, 85, 1062], 'by': [29, 89, 128, 147, 197, 257, 523, 1041, 1090, 1109, 1216, 1238, 1281, 1300], 'UVB': [30, 90, 167, 181, 235, 258, 367, 479, 1092], 'is': [31, 42, 91, 159, 259, 268, 333, 422, 459, 531, 683, 700, 716, 1075, 1186, 1218, 1240, 1266], 'crucially': [32], 'involved': [33, 326, 418, 631], 'both': [35, 48], 'effects': [36, 172, 293, 371, 602, 623, 1017, 1025], 'because': [37, 262, 797], 'reduction': [38, 46, 272, 1148], 'associated': [43, 269], 'with': [44, 193, 270, 636, 788], 'a': [45, 271, 617, 646, 719, 801, 829, 1080, 1278, 1290], 'immunosuppression.': [51, 133], 'The': [52, 621, 710, 816], 'immunomodulatory': [53, 988, 1056], 'cytokine': [54, 513, 1057, 1081, 1169], 'interleukin-12': [55], '(IL-12)': [56], 'has': [57], 'been': [58], 'recently': [59], 'discovered': [60], 'to': [61, 65, 296, 305, 349, 363, 398, 475, 792, 880, 902, 908, 996, 1002, 1013, 1084, 1170, 1173, 1176, 1189, 1245], 'exhibit': [62], 'capacity': [64, 993, 1244], 'reduce': [66, 1059, 1246], 'UV-induced': [67, 99, 420, 633, 767, 812, 836, 849, 883, 1005, 1236, 1247, 1298], 'via': [70, 173, 214, 336, 372, 533, 605, 685, 702, 731, 1022, 1064, 1094, 1147, 1158, 1242], 'nucleotide': [74, 1067, 1103, 1162], 'excision': [75, 1068, 1104, 1163], 'repair,': [76, 1069, 1097], 'endogenous': [78, 1071], 'repair': [80, 1072, 1105, 1294], 'Langerhans': [87, 112, 1259], 'cells': [88, 104, 113, 303, 545, 715, 724, 730, 770, 825, 852, 886, 930, 1086, 1260], 'an': [92, 354, 403, 470, 650, 1285], 'essential': [93, 404, 473], 'event': [94], 'development': [97, 1270], 'regulatory': [100, 768, 813, 823, 837, 850, 884, 928, 1272], 'T': [101, 139, 283, 488, 558, 769, 814, 824, 838, 851, 885, 929, 1116, 1273], 'cells.': [102, 815, 839, 1274], 'only': [105, 184, 657, 855, 890, 950, 995], 'develop': [106], 'on': [107, 440, 659, 665, 822, 951, 955, 1220], 'appearance': [109], 'DNA-damaged': [111], 'draining': [116], 'lymph': [117, 935, 1264], 'nodes.': [118], 'Because': [119, 919], 'IL-12': [120, 130, 966, 1008, 1165, 1190, 1217, 1239, 1283], 'reduces': 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'al.': [209, 677, 848, 965, 1035, 1119], 'Ultraviolet': [210, 678], 'light': [211, 679], 'induces': [212], 'direct': [215], 'activation': [216, 252, 267, 343, 392, 436, 606], 'CD95': [218, 733], '(FAS/APO-1)': [219], 'independently': [220, 295], 'from': [221, 498, 520, 548, 568, 574, 1087, 1123, 1144], 'ligand': [223, 526, 706, 781], 'CD95L.': [224], 'J': [225, 501, 578, 689, 758, 869, 977, 1130, 1223], 'Cell': [226, 1046], 'Biol': [227, 502, 579, 1047, 1131], '1998:': [228, 504, 691], '140:': [229], '71–182.': [230], 'article': [232, 318, 360, 413, 508, 585, 695, 764, 875, 984, 1052, 1137, 1230, 1251], 'demonstrates': [233, 319, 414, 509, 586, 696, 765, 876, 985, 1053, 1138, 1182, 1231], 'directly': [238], 'activate': [239], 'death': [241, 255, 265, 332, 345, 352, 390, 438, 525, 590, 637], 'receptor': [242, 256, 266, 391], 'CD95/FAS': [243], 'without': [244], 'need': [246], 'cognate': [249], 'ligand.': [250], 'Direct': [251], 'functionally': [260], 'relevant': [261], 'inhibition': 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'reactive': [394, 447], 'oxygen': [395, 448], 'species': [396], 'radiation-induced': [400, 576, 756, 1039, 1125, 1214], 'way.': [407], 'Oncogene': [408], '2002:': [409, 1048], '21:': [410], '5844–5851.': [411], 'signaling': [416], 'pathway': [417], 'more': [423], 'complex': [424], 'additional': [427], 'involved.': [430], 'surface,': [443], 'species.': [449], 'Only': [450], 'when': [451], 'all': [452, 465], 'three': [453, 466], 'blocked,': [456], 'completely': [460], 'prevented.': [461], 'indicates': [463, 1253], 'fashion': [474], 'effect': [477, 530, 551, 1153, 1185], 'Kothny-Wilkes': [481, 554], 'G,': [482], 'Kubin': [490, 560], 'M,': [491, 561, 1033, 1112], 'Interleukin-1': [494, 564], 'protects': [495, 565, 1122, 1142], 'transformed': [496, 518, 566], 'keratinocytes': [497, 519, 567], 'TRAIL-induced': [499], 'Chem': [503, 580, 1132], '273:': [505], '29247–29253.': [506], 'proinflammatory': [512], 'interleukin-1': [514], '(IL-1)': [515], 'protect': [517, 1085], 'induced': [522, 680, 969, 975, 1089], 'TRAIL.': [527, 553], 'protective': [529], 'upregulation': [535], 'transcription': [538], 'factor': [539], 'NF-κB.': [540, 608], 'Via': [541], 'mechanism,': [543], 'tumor': [544], 'might': [546], 'escape': [547], 'cytotoxic': [550], 'TRAIL-': [569], 'CD95-': [571], '274:': [582], '28916–28921.': [583], 'IL-1': [588, 625], 'ligand-induced': [591], 'contrast': [595, 879], 'enhances': [596], 'death.': [599], 'Both': [600], 'diverse': [601], 'Thus,': [609, 1007], 'NF-κB': [610], 'cannot': [611], 'be': [612, 793, 909, 1107, 1156, 1171, 1174], 'any': [613], 'longer': [614], 'regarded': [615], 'as': [616, 828], 'universal': [618], 'anti-apoptotic': [619, 651], 'factor.': [620], 'opposite': [622], 'indicate': [626], 'mechanisms': [629], 'compared': [635], 'ligand-mediated': [638], 'Furthermore,': [640], 'data': [642, 1276], 'suggest': [643], 'whether': [645], 'acts': [648], 'way': [652], 'or': [653], 'does': [655], 'depend': [658], 'itself': [662], 'stimulus': [667], 'causing': [668], 'Grabbe': [672, 960], 'S,': [673, 961, 1031, 1208], 'Grosse-Heitmeyer': [674], 'K,': [675, 748, 846, 1203], 'tolerance': [682, 699], 'CD95/CD95-ligand': [687], 'Immunol': [690, 759, 870], '160:': [692], '4262–4270.': [693], 'apoptosis-related': [704], 'CD95/CD95': [705], '(FAS/FAS': [707], 'ligand)': [708], 'activity': [711, 810], 'suppressor': [714], 'lost': [717], 'CD95-deficient': [720], 'environment.': [721], 'T-suppressor': [723], 'may': [725, 826, 1009, 1154, 1192], 'induce': [726], 'antigen-presenting': [729], 'system': [734], 'thereby': [736], 'prevent': [737, 997, 1014], 'sensitization.': [738], 'Maeda': [741, 842, 1200], 'Tezuka': [745], 'T,': [746], 'Ariizumi': [747], 'Involvement': [751], 'dectin-2': [753, 787, 806, 821], 'UV': [755, 1213], 'tolerance.': [757, 976, 1006], '2003:': [760], '171:': [761], '3801–3807.': [762], 'bind': [771], 'lectin': [773], 'dectin-2,': [774], 'indicating': [775], 'they': [777, 906, 945], 'express': [778], 'yet-unknown': [780], 'for': [782, 832, 1195, 1268], 'lectin.': [784], 'Interaction': [785], 'ligand/receptor': [790], 'appears': [791], 'functional': [795], 'relevance': [796], 'injection': [799], 'soluble': [802], 'fusion': [803], 'protein': [804], 'inhibits': [807], 'suppressive': [809], 'expression': [817, 923], 'receptor-binding': [820], 'serve': [827], 'unique': [830, 922], 'marker': [831], 'identification': [834], 'Wild': [844], 'M': [845], 'do': [853], 'inhibit': [856], 'suppress': [862, 888, 946], 'effector': [864, 896, 948], 'phase': [865, 897, 949], 'contact': [867, 899], 'hypersensitivity.': [868, 900], '2004:': [871], '172:': [872], '1036–1043.': [873], 'previous': [881], 'assumptions,': [882], 'effect,': [905], 'have': [907], 'present': [910], 'periphery': [913], 'where': [914], 'inflammation': [916], 'takes': [917], 'place.': [918], 'pattern': [924], 'homing': [926], 'receptors,': [927], 'preferentially': [931], 'migrate': [932], 'into': [933, 939], 'nodes': [936, 1265], 'periphery.': [941], 'why': [944], 'intralesional': [952], 'intravenous': [956], 'injection.': [957], 'ultraviolet-B': [968, 974], 'local': [970], 'immunosuppression': [971, 999, 1215, 1237, 1299], 'breaks': [973], 'Invest': [978], 'Dermatol': [979], '1996:': [980], '106:': [981], '1187–1191.': [982], 'cytokine,': [989], 'IL-12,': [990], 'exhibits': [991], 'break': [1003], 'established': [1004], 'bear': [1010], 'potential': [1012], 'adverse': [1016], 'solar/UV': [1019], 'immunosuppressive': [1024], 'including': [1026], 'photocarcinogenesis.': [1027], 'Ständer': [1030], 'Berneburg': [1032], 'Interleukin-12': [1036], 'suppresses': [1037], 'inducing': [1042], 'repair.': [1044, 1164, 1179, 1222], 'Nat': [1045], '4:': [1049], '26–31.': [1050], 'presumably': [1063], 'demonstration': [1078], 'being': [1082], 'able': [1083, 1175], 'DNA-damaging': [1091], 'second,': [1099], 'influenced': [1108], 'cytokines.': [1110], 'Böhm': [1111], 'Wolff': [1113], 'I,': [1114], 'Scholzen': [1115], 'Alpha-melanocyte-stimulating': [1120], 'hormone': [1121, 1141], '2005:': [1133, 1226], '280:': [1134], '5795–5802.': [1135], 'alpha-melanocyte-stimulating': [1140], 'melanocytes': [1143], 'was': [1166], 'demonstrated': [1172], 'affect': [1177], 'study': [1181], 'restricted': [1188], 'apply': [1194], 'other': [1196], 'mediators.': [1197], 'Kernebeck': [1202], 'van': [1204], 'Steeg': [1205], 'H,': [1206], 'Beissert': [1207], 'Prevention': [1211], 'dependent': [1219], 'Exp': [1224], 'Med': [1225], '201:': [1227], '173–179.': [1228], 'prevention': [1234, 1296], 'presence': [1256], 'UV-damaged': [1258], 'regional': [1263], 'crucial': [1267], 'identify': [1277], 'new': [1279], 'restores': [1284], 'response': [1287], 'demonstrate': [1289], 'link': [1291], 'between': [1292], 'IL-12.': [1301]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1981111315', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-09T09:01:17.555694', 'created_date': '2016-06-24'}