Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1981086346', 'doi': 'https://doi.org/10.1016/j.febslet.2006.05.009', 'title': 'An essential role of Cdc42‐like GTPases in mitosis of HeLa cells', 'display_name': 'An essential role of Cdc42‐like GTPases in mitosis of HeLa cells', 'publication_year': 2006, 'publication_date': '2006-05-11', 'ids': {'openalex': 'https://openalex.org/W1981086346', 'doi': 'https://doi.org/10.1016/j.febslet.2006.05.009', 'mag': '1981086346', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16716304'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.febslet.2006.05.009', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2006.05.009', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2006.05.009', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076963406', 'display_name': 'Shingo Yasuda', 'orcid': 'https://orcid.org/0000-0003-1019-2459'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shingo Yasuda', 'raw_affiliation_strings': ['Department of Pharmacology, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}, {'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087279007', 'display_name': 'Hiroyuki Taniguchi', 'orcid': 'https://orcid.org/0000-0001-9718-0711'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroyuki Taniguchi', 'raw_affiliation_strings': ['Department of Pharmacology, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}, {'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061248029', 'display_name': 'Fabian Oceguera-Yañez', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Fabian Oceguera-Yanez', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048279225', 'display_name': 'Yukio Ando', 'orcid': 'https://orcid.org/0000-0001-7115-9105'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshikazu Ando', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111712483', 'display_name': 'Sadanori Watanabe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sadanori Watanabe', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071383065', 'display_name': 'James Monypenny', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'James Monypenny', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5024624058', 'display_name': 'Shuh Narumiya', 'orcid': 'https://orcid.org/0000-0001-8062-6529'}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Shuh Narumiya', 'raw_affiliation_strings': ['Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Horizontal Medical Research Organization, Kyoto University, Faculty of Medicine, Kyoto 606-8501, Japan', 'institution_ids': ['https://openalex.org/I22299242']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5024624058'], 'corresponding_institution_ids': ['https://openalex.org/I22299242'], 'apc_list': {'value': 3610, 'currency': 'USD', 'value_usd': 3610, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.083, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 35, 'citation_normalized_percentile': {'value': 0.82812, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '580', 'issue': '14', 'first_page': '3375', 'last_page': '3380'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10123', 'display_name': 'DNA Repair Mechanisms', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10434', 'display_name': 'Chromosomal and Genetic Variations', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cdc42', 'display_name': 'CDC42', 'score': 0.91480565}], 'concepts': [{'id': 'https://openalex.org/C207332259', 'wikidata': 'https://www.wikidata.org/wiki/Q769143', 'display_name': 'GTPase', 'level': 2, 'score': 0.9170857}, {'id': 'https://openalex.org/C2780040266', 'wikidata': 'https://www.wikidata.org/wiki/Q15311701', 'display_name': 'CDC42', 'level': 3, 'score': 0.91480565}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.711594}, {'id': 'https://openalex.org/C93304396', 'wikidata': 'https://www.wikidata.org/wiki/Q14763008', 'display_name': 'Mitosis', 'level': 2, 'score': 0.60675764}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44885278}], 'mesh': [{'descriptor_ui': 'D008938', 'descriptor_name': 'Mitosis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D020764', 'descriptor_name': 'cdc42 GTP-Binding Protein', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005455', 'descriptor_name': 'Fluorescent Antibody Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008938', 'descriptor_name': 'Mitosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020764', 'descriptor_name': 'cdc42 GTP-Binding Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.febslet.2006.05.009', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2006.05.009', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16716304', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.febslet.2006.05.009', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2006.05.009', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 16, 'referenced_works': ['https://openalex.org/W1587960910', 'https://openalex.org/W2002964349', 'https://openalex.org/W2004619403', 'https://openalex.org/W2007354846', 'https://openalex.org/W2011233324', 'https://openalex.org/W2019731805', 'https://openalex.org/W202053380', 'https://openalex.org/W2079337167', 'https://openalex.org/W2085700440', 'https://openalex.org/W2094051555', 'https://openalex.org/W2095562167', 'https://openalex.org/W2103206182', 'https://openalex.org/W2120383922', 'https://openalex.org/W2120909571', 'https://openalex.org/W2152462023', 'https://openalex.org/W2159340323'], 'related_works': ['https://openalex.org/W3195062933', 'https://openalex.org/W2080304943', 'https://openalex.org/W2069372950', 'https://openalex.org/W2067854585', 'https://openalex.org/W2066265974', 'https://openalex.org/W2040571096', 'https://openalex.org/W1981086346', 'https://openalex.org/W1601656562', 'https://openalex.org/W1503951074', 'https://openalex.org/W146073455'], 'abstract_inverted_index': {'Here': [0], 'we': [1], 'used': [2], 'RNA': [3], 'interference': [4], 'and': [5, 27, 59], 'examined': [6], 'possible': [7], 'redundancy': [8], 'amongst': [9], 'Rho': [10], 'GTPases': [11, 41, 49, 66, 89], 'in': [12, 21, 96], 'their': [13], 'mitotic': [14, 94], 'role.': [15], 'Chromosome': [16], 'misalignment': [17], 'is': [18, 76], 'induced': [19], 'significantly': [20, 67], 'HeLa': [22], 'cells': [23], 'by': [24, 29], 'Cdc42': [25, 58, 75], 'depletion': [26, 30, 56], 'not': [28], 'of': [31, 36, 57, 61], 'either': [32], 'one': [33], 'or': [34, 45, 50], 'all': [35, 60], 'the': [37, 62, 77, 85, 93], 'other': [38, 63, 86], 'four': [39, 47, 64, 87], 'Cdc42‐like': [40, 65, 88], '(TC10,': [42], 'TCL,': [43], 'Wrch1': [44], 'Wrch2),': [46], 'Rac‐like': [48], 'three': [51], 'Rho‐like': [52], 'GTPases.': [53], 'Notably,': [54], 'combined': [55], 'enhances': [68], 'chromosomal': [69], 'misalignment.': [70], 'These': [71], 'observations': [72], 'suggest': [73], 'that': [74, 84], 'primary': [78], 'GTPase': [79], 'functioning': [80], 'during': [81], 'mitosis': [82], 'but': [83], 'can': [90], 'also': [91], 'assume': [92], 'role': [95], 'its': [97], 'absence.': [98]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1981086346', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-09T04:49:23.692044', 'created_date': '2016-06-24'}