Title: A rapid, solid phase radioimmunoassay for prostaglandin F2α and its main circulating metabolite
Abstract: Antibodies directed against prostaglandin F2α and its main circulating metabolite, 13,14-dihydro-15-keto-prostaglandin F2α, were insolubilized by reaction with ethylchloroformate. Suspensions of insolubilized antibodies retained immunogenic activity and were useful for the development of a simple and rapid solid phase radioimmunoassay for these two prostaglandins. Using this method, suppression of prostaglandin levels by the influence of indomethacin in vivo has been observed. Advantages of solid phase radioimmunoassay over current procedures are discussed.
Publication Year: 1976
Publication Date: 1976-05-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 31
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot