Title: Simulatneous determination of baicalein, wogonin, oroxylin-A and their glucuronides in scutellariae radix by ion-pair high-performance liquid chromatography
Abstract: A new, simple and precise analytical method using ion-pair high-performance liquid chromatography was developed for simultaneous of six flavonoids, namely baicalin, baicalein, wogonin, wogonin-glucuronide, oroxylin-A and oroxylin-A-glucuronide, in Scutellariae Radix. A reversed-phase chromatographic system consisting of a chemically bonded ODS silica gel column and water—acetonitrile (68:32), containing 5mM tetra-n-amylammonium bromide and adjusted to pH 4.0 by phosphoric acid, as mobile phase was used. The six flavonoids in this crude drug were completely separated within 25 min. Oroxylin-A and its glucuronide were separated for the first time. The analytical results for various samples are described.
Publication Year: 1985
Publication Date: 1985-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 26
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