Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1979886380', 'doi': 'https://doi.org/10.1016/j.juro.2010.02.1564', 'title': '1717 BILHARZIAL RELATED BLADDER CANCER: PATHOLOGICAL CHARACTERISTICS AND VALUE OF CYCLOOXYGENASE-2 EXPRESSION', 'display_name': '1717 BILHARZIAL RELATED BLADDER CANCER: PATHOLOGICAL CHARACTERISTICS AND VALUE OF CYCLOOXYGENASE-2 EXPRESSION', 'publication_year': 2010, 'publication_date': '2010-03-23', 'ids': {'openalex': 'https://openalex.org/W1979886380', 'doi': 'https://doi.org/10.1016/j.juro.2010.02.1564', 'mag': '1979886380'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2010.02.1564', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109137714', 'display_name': 'Ramy F. Youssef', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ramy Youssef', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069595062', 'display_name': 'Payal Kapur', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Payal Kapur', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069582117', 'display_name': 'Wareef Kabbani', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wareef Kabbani', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079401169', 'display_name': 'Shahrokh F. Shariat', 'orcid': 'https://orcid.org/0000-0002-6627-6179'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Shahrokh Shariat', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103390448', 'display_name': 'Ahmed Mosbah', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159247623', 'display_name': 'Mansoura University', 'ror': 'https://ror.org/01k8vtd75', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I159247623']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Ahmed Mosbah', 'raw_affiliation_strings': ['Mansoura, Egypt'], 'affiliations': [{'raw_affiliation_string': 'Mansoura, Egypt', 'institution_ids': ['https://openalex.org/I159247623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070428699', 'display_name': 'Hassan Abol‐Enein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159247623', 'display_name': 'Mansoura University', 'ror': 'https://ror.org/01k8vtd75', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I159247623']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Hassan Abol-Enein', 'raw_affiliation_strings': ['Mansoura, Egypt'], 'affiliations': [{'raw_affiliation_string': 'Mansoura, Egypt', 'institution_ids': ['https://openalex.org/I159247623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113647698', 'display_name': 'Mohamed Ghoniem', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159247623', 'display_name': 'Mansoura University', 'ror': 'https://ror.org/01k8vtd75', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I159247623']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Mohamed Ghoniem', 'raw_affiliation_strings': ['Mansoura, Egypt'], 'affiliations': [{'raw_affiliation_string': 'Mansoura, Egypt', 'institution_ids': ['https://openalex.org/I159247623']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5041923034', 'display_name': 'Yair Lotan', 'orcid': 'https://orcid.org/0000-0001-5692-2723'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yair Lotan', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.283, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.525951, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 64, 'max': 71}, 'biblio': {'volume': '183', 'issue': '4S', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.9908, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9836, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pathological-staging', 'display_name': 'Pathological staging', 'score': 0.41372234}], 'concepts': [{'id': 'https://openalex.org/C2775910329', 'wikidata': 'https://www.wikidata.org/wiki/Q245995', 'display_name': 'Cystectomy', 'level': 4, 'score': 0.8058953}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.76974225}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.70909685}, {'id': 'https://openalex.org/C207886595', 'wikidata': 'https://www.wikidata.org/wiki/Q1456138', 'display_name': 'Pathological', 'level': 2, 'score': 0.67355037}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.5672288}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.46437895}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.44109362}, {'id': 'https://openalex.org/C2779689624', 'wikidata': 'https://www.wikidata.org/wiki/Q410251', 'display_name': 'Cyclooxygenase', 'level': 3, 'score': 0.42496538}, {'id': 'https://openalex.org/C2992528526', 'wikidata': 'https://www.wikidata.org/wiki/Q1752284', 'display_name': 'Pathological staging', 'level': 3, 'score': 0.41372234}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.38000506}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.35820246}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0871461}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2010.02.1564', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'No poverty', 'id': 'https://metadata.un.org/sdg/1', 'score': 0.57}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3128330365', 'https://openalex.org/W3127820018', 'https://openalex.org/W3027336582', 'https://openalex.org/W2904128870', 'https://openalex.org/W2899655305', 'https://openalex.org/W2595618663', 'https://openalex.org/W2383341741', 'https://openalex.org/W2189722039', 'https://openalex.org/W2167198546', 'https://openalex.org/W2109785281'], 'abstract_inverted_index': {'You': [0], 'have': [1], 'accessJournal': [2], 'of': [3, 146, 229, 280, 330, 418], 'UrologyBladder': [4], 'Cancer:': [5], 'Invasive/Metastatic': [6], 'Disease': [7], 'II1': [8], 'Apr': [9], '20101717': [10], 'BILHARZIAL': [11], 'RELATED': [12], 'BLADDER': [13], 'CANCER:': [14], 'PATHOLOGICAL': [15], 'CHARACTERISTICS': [16], 'AND': [17, 139], 'VALUE': [18], 'OF': [19], 'CYCLOOXYGENASE-2': [20], 'EXPRESSION': [21], 'Ramy': [22, 39, 465], 'Youssef,': [23], 'Payal': [24, 50, 474], 'Kapur,': [25], 'Wareef': [26, 61, 483], 'Kabbani,': [27], 'Shahrokh': [28, 72, 492], 'Shariat,': [29], 'Ahmed': [30, 83, 501], 'Mosbah,': [31], 'Hassan': [32, 94, 510], 'Abol-Enein,': [33], 'Mohamed': [34, 105, 519], 'Ghoniem,': [35], 'and': [36, 116, 151, 157, 159, 178, 213, 255, 272, 278, 295, 339, 355, 378, 385, 396, 420, 440, 461], 'Yair': [37, 117, 528], 'Lotan': [38, 119, 529], 'YoussefRamy': [40], 'Youssef': [41, 466], 'Dallas,': [42, 53, 64, 75, 120, 467, 476, 485, 494, 530], 'TX': [43, 54, 65, 76, 121, 468, 477, 486, 495, 531], 'More': [44, 55, 66, 77, 88, 99, 110, 122, 469, 478, 487, 496, 505, 514, 523, 532], 'articles': [45, 56, 67, 78, 89, 100, 111, 123, 470, 479, 488, 497, 506, 515, 524, 533], 'by': [46, 57, 68, 79, 90, 101, 112, 124, 435, 456, 471, 480, 489, 498, 507, 516, 525, 534], 'this': [47, 58, 69, 80, 91, 102, 113, 125, 472, 481, 490, 499, 508, 517, 526, 535], 'author': [48, 59, 70, 81, 92, 103, 114, 126, 473, 482, 491, 500, 509, 518, 527, 536], ',': [49, 60, 71, 82, 93, 104, 115], 'KapurPayal': [51], 'Kapur': [52, 475], 'KabbaniWareef': [62], 'Kabbani': [63, 484], 'ShariatShahrokh': [73], 'Shariat': [74, 493], 'MosbahAhmed': [84], 'Mosbah': [85, 502], 'Mansoura,': [86, 97, 108, 503, 512, 521], 'Egypt': [87, 98, 109, 504, 513, 522], 'Abol-EneinHassan': [95], 'Abol-Enein': [96, 511], 'GhoniemMohamed': [106], 'Ghoniem': [107, 520], 'LotanYair': [118], 'View': [127], 'All': [128, 538], 'Author': [129], 'Informationhttps://doi.org/10.1016/j.juro.2010.02.1564AboutPDF': [130], 'ToolsAdd': [131], 'to': [132], 'favoritesDownload': [133], 'CitationsTrack': [134], 'CitationsPermissionsReprints': [135], 'ShareFacebookTwitterLinked': [136], 'InEmail': [137], 'INTRODUCTION': [138], 'OBJECTIVES': [140], 'We': [141, 170], 'assessed': [142], 'the': [143, 173, 413], 'expression': [144, 228, 366], 'pattern': [145], 'cyclooxygenase-2': [147], '(cox-2)': [148], 'in': [149, 236, 274, 288, 307, 367, 372, 431], 'bilharzial': [150], 'non-bilharzial': [152], 'related': [153], 'bladder': [154, 189], 'cancer': [155], '(BBC': [156], 'NBBC)': [158], 'its': [160], 'association': [161], 'with': [162, 195, 211, 220, 233, 259, 363, 400, 405], 'poor': [163], 'clinical': [164, 234, 296], 'outcome': [165, 235, 297, 407], 'after': [166, 408], 'radical': [167], 'cystectomy': [168], '(RC).': [169], 'also': [171], 'determined': [172], 'clinico-pathological': [174], 'differences': [175, 223], 'between': [176, 197, 298, 314], 'BBC': [177, 212, 382], 'NBBC.': [179, 221, 388], 'METHODS': [180], 'Immunohistochemical(IHC)': [181], 'staining': [182], 'for': [183, 415], 'cox-2': [184, 230, 323, 365, 401, 419], 'was': [185, 231, 241, 284, 304, 361], 'performed': [186], 'on': [187], 'archival': [188], 'specimens': [190], 'from': [191, 387], '315': [192, 250], 'patients': [193, 209, 218, 251, 281, 331], 'treated': [194], 'RC': [196], '1997-2003.': [198], 'Patients': [199], 'were': [200, 224, 336], 'divided': [201], 'into': [202], '2': [203, 215, 374], 'groups:': [204], 'Group': [205], '1': [206, 369], 'comprised': [207, 216], '205': [208], '(65%)': [210], 'group': [214, 327, 345, 368, 373], '110': [217], '(35%)': [219], 'Clinico-pathological': [222], 'compared.': [225], 'Altered': [226], 'IHC': [227], 'correlated': [232], 'both': [237, 299, 315], 'groups.': [238, 301], 'Mean': [239], 'follow-up': [240], '3': [242], 'y': [243, 263], '(range': [244, 264], '0-8).': [245], 'RESULTS': [246], 'The': [247], 'study': [248, 300], 'included': [249], '[239': [252], '(76%)': [253], 'males': [254], '76': [256], '(24%)': [257], 'females]': [258], 'mean': [260], 'age': [261], '53.5': [262], '31-79).': [265], 'Pathological': [266], 'diagnosis': [267], 'showed': [268, 332, 348, 352], 'PT1,': [269], 'PT2,': [270], 'PT3': [271], 'PT4': [273], '12%,': [275], '40%,': [276], '40%': [277], '8%': [279], 'respectively.': [282], 'There': [283], 'no': [285], 'significant': [286, 305], 'difference': [287, 306], 'pathological': [289, 308], 'T': [290], 'stage,': [291], 'LN,': [292], 'lymphovascular': [293], 'invasion,': [294], 'However,': [302], 'there': [303], 'cell': [309], 'type,': [310], 'grade,': [311], 'tumor': [312], 'architecture': [313], 'groups': [316], '[p': [317], '=': [318, 376], '0.00]': [319], 'as': [320, 322, 424, 426], 'well': [321, 425], 'alterations': [324, 402], '(p=0.045).': [325], 'In': [326, 344], '1:': [328], '2/3': [329, 340, 347, 356], 'non-urothelial': [333, 397], 'carcinoma,': [334, 350], '85%': [335, 351], 'low': [337], 'grade': [338, 354], 'had': [341, 357], 'non-papillary': [342], 'architecture.': [343, 359], '2:': [346], 'urothelial': [349], 'high': [353], 'papillary': [358, 395], 'Recurrence': [360], 'associated': [362, 404], 'altered': [364], 'but': [370], 'not': [371], '(p': [375], '0.012': [377], '0.38': [379], 'respectively).': [380], 'CONCLUSIONS': [381], 'differs': [383], 'pathologically': [384], 'biologically': [386], 'BBCs': [389, 399], 'are': [390, 403], 'more': [391], 'frequently': [392], 'low-grade,': [393], 'non-': [394], 'cancers.': [398], 'worse': [406], 'RC.': [409], 'Our': [410], 'findings': [411], 'support': [412], 'need': [414], 'further': [416], 'evaluation': [417], 'inflammatory': [421], 'signaling': [422], 'pathways': [423], 'cox-2-targeted': [427], 'prevention': [428], 'or': [429], 'therapies': [430], 'BBC.': [432], '©': [433], '2010': [434, 455], 'American': [436, 457], 'Urological': [437, 458], 'Association': [438, 459], 'Education': [439, 460], 'Research,': [441, 462], 'Inc.FiguresReferencesRelatedDetails': [442], 'Volume': [443], '183Issue': [444], '4SApril': [445], '2010Page:': [446], 'e663': [447], 'Peer': [448], 'Review': [449], 'Report': [450], 'Advertisement': [451, 539, 540], 'Copyright': [452], '&': [453], 'Permissions©': [454], 'Inc.MetricsAuthor': [463], 'Information': [464], 'Expand': [537], 'PDF': [541], 'downloadLoading': [542], '...': [543]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1979886380', 'counts_by_year': [], 'updated_date': '2024-12-24T15:58:07.117912', 'created_date': '2016-06-24'}