Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1978577250', 'doi': 'https://doi.org/10.1074/jbc.m001857200', 'title': 'Platelet-Endothelial Cell Adhesion Molecule-1 (CD31), a Scaffolding Molecule for Selected Catenin Family Members Whose Binding Is Mediated by Different Tyrosine and Serine/Threonine Phosphorylation', 'display_name': 'Platelet-Endothelial Cell Adhesion Molecule-1 (CD31), a Scaffolding Molecule for Selected Catenin Family Members Whose Binding Is Mediated by Different Tyrosine and Serine/Threonine Phosphorylation', 'publication_year': 2000, 'publication_date': '2000-07-01', 'ids': {'openalex': 'https://openalex.org/W1978577250', 'doi': 'https://doi.org/10.1074/jbc.m001857200', 'mag': '1978577250', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10801826'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m001857200', 'pdf_url': 'http://www.jbc.org/article/S0021925819797749/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925819797749/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5051815910', 'display_name': 'Neta Ilan', 'orcid': 'https://orcid.org/0000-0003-3549-4904'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Neta Ilan', 'raw_affiliation_strings': ['Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023373527', 'display_name': 'Larry Cheung', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Larry Cheung', 'raw_affiliation_strings': ['From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520.'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520.', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038558402', 'display_name': 'Emese Pinter', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Emese Pinter', 'raw_affiliation_strings': ['From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520.'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520.', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5016134289', 'display_name': 'Joseph A. Madri', 'orcid': 'https://orcid.org/0000-0003-0008-2440'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joseph A. Madri', 'raw_affiliation_strings': ['From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520.'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520.', 'institution_ids': ['https://openalex.org/I32971472']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 3.898, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 121, 'citation_normalized_percentile': {'value': 0.94747, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '275', 'issue': '28', 'first_page': '21435', 'last_page': '21443'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt/β-catenin signaling in development and cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cell-signaling', 'display_name': 'Cell Signaling', 'score': 0.41118845}], 'concepts': [{'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.7340398}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.71568704}, {'id': 'https://openalex.org/C2777553839', 'wikidata': 'https://www.wikidata.org/wiki/Q14330986', 'display_name': 'Tyrosine phosphorylation', 'level': 3, 'score': 0.6593017}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.6038481}, {'id': 'https://openalex.org/C30145163', 'wikidata': 'https://www.wikidata.org/wiki/Q384104', 'display_name': 'Catenin', 'level': 4, 'score': 0.59050137}, {'id': 'https://openalex.org/C16224149', 'wikidata': 'https://www.wikidata.org/wiki/Q187637', 'display_name': 'Cell adhesion molecule', 'level': 2, 'score': 0.55283535}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5391147}, {'id': 'https://openalex.org/C85789140', 'wikidata': 'https://www.wikidata.org/wiki/Q187640', 'display_name': 'Cell adhesion', 'level': 3, 'score': 0.5048235}, {'id': 'https://openalex.org/C2776165026', 'wikidata': 'https://www.wikidata.org/wiki/Q188017', 'display_name': 'Tyrosine', 'level': 2, 'score': 0.47273436}, {'id': 'https://openalex.org/C42362537', 'wikidata': 'https://www.wikidata.org/wiki/Q87099740', 'display_name': 'Tyrosine kinase', 'level': 3, 'score': 0.4625821}, {'id': 'https://openalex.org/C123012128', 'wikidata': 'https://www.wikidata.org/wiki/Q5376430', 'display_name': 'Endothelial stem cell', 'level': 3, 'score': 0.44688058}, {'id': 'https://openalex.org/C195794163', 'wikidata': 'https://www.wikidata.org/wiki/Q420877', 'display_name': 'Protein kinase C', 'level': 3, 'score': 0.43429026}, {'id': 'https://openalex.org/C150555746', 'wikidata': 'https://www.wikidata.org/wiki/Q210973', 'display_name': 'Cell signaling', 'level': 3, 'score': 0.41118845}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23858002}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.21744725}, {'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.1319867}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.06877869}], 'mesh': [{'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D019408', 'descriptor_name': 'Platelet Endothelial Cell Adhesion Molecule-1', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015815', 'descriptor_name': 'Cell Adhesion Molecules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015815', 'descriptor_name': 'Cell Adhesion Molecules', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051180', 'descriptor_name': 'Desmoplakins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004622', 'descriptor_name': 'Embryo, Mammalian', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004622', 'descriptor_name': 'Embryo, Mammalian', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010768', 'descriptor_name': 'Phosphoserine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010768', 'descriptor_name': 'Phosphoserine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010769', 'descriptor_name': 'Phosphothreonine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010769', 'descriptor_name': 'Phosphothreonine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019000', 'descriptor_name': 'Phosphotyrosine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019000', 'descriptor_name': 'Phosphotyrosine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019408', 'descriptor_name': 'Platelet Endothelial Cell Adhesion Molecule-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019408', 'descriptor_name': 'Platelet Endothelial Cell Adhesion Molecule-1', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D011493', 'descriptor_name': 'Protein Kinase C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011493', 'descriptor_name': 'Protein Kinase C', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014471', 'descriptor_name': 'Umbilical Veins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015017', 'descriptor_name': 'Yolk Sac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015017', 'descriptor_name': 'Yolk Sac', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051185', 'descriptor_name': 'gamma Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m001857200', 'pdf_url': 'http://www.jbc.org/article/S0021925819797749/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10801826', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m001857200', 'pdf_url': 'http://www.jbc.org/article/S0021925819797749/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W1536518696', 'https://openalex.org/W1554815317', 'https://openalex.org/W1578194145', 'https://openalex.org/W1755902553', 'https://openalex.org/W1819034630', 'https://openalex.org/W1914409163', 'https://openalex.org/W1931818816', 'https://openalex.org/W1938469840', 'https://openalex.org/W1971324629', 'https://openalex.org/W1972659626', 'https://openalex.org/W1975818706', 'https://openalex.org/W1977199477', 'https://openalex.org/W1982687474', 'https://openalex.org/W1986070215', 'https://openalex.org/W1993342205', 'https://openalex.org/W2001141799', 'https://openalex.org/W2002404925', 'https://openalex.org/W2003958144', 'https://openalex.org/W2004472590', 'https://openalex.org/W2005088732', 'https://openalex.org/W2008034243', 'https://openalex.org/W2014730766', 'https://openalex.org/W2014995450', 'https://openalex.org/W2018587071', 'https://openalex.org/W2025142983', 'https://openalex.org/W2032362666', 'https://openalex.org/W2035356593', 'https://openalex.org/W2049866297', 'https://openalex.org/W2055087999', 'https://openalex.org/W2058067037', 'https://openalex.org/W2059759744', 'https://openalex.org/W2060176983', 'https://openalex.org/W2062911730', 'https://openalex.org/W2079583982', 'https://openalex.org/W2079959342', 'https://openalex.org/W2084555620', 'https://openalex.org/W2090895449', 'https://openalex.org/W2102015925', 'https://openalex.org/W2109069210', 'https://openalex.org/W2115944612', 'https://openalex.org/W2118252933', 'https://openalex.org/W2125878895', 'https://openalex.org/W2140717323', 'https://openalex.org/W2146787008', 'https://openalex.org/W2154701839', 'https://openalex.org/W2166833739', 'https://openalex.org/W2400600154', 'https://openalex.org/W2410831513', 'https://openalex.org/W26093464', 'https://openalex.org/W348127839', 'https://openalex.org/W95153881'], 'related_works': ['https://openalex.org/W4252597221', 'https://openalex.org/W2403922722', 'https://openalex.org/W2333958926', 'https://openalex.org/W2171277650', 'https://openalex.org/W2152583801', 'https://openalex.org/W2033441570', 'https://openalex.org/W2030033027', 'https://openalex.org/W2006626122', 'https://openalex.org/W1987307749', 'https://openalex.org/W1591309477'], 'abstract_inverted_index': {'Platelet-endothelial': [0, 165, 359], 'cell': [1, 27, 166, 192, 331, 360, 375, 461, 465, 718, 1437, 1718, 2123, 2683, 2877, 3439, 3516, 3523], 'adhesion': [2, 167, 332, 361, 376, 505], 'molecule': [3, 168, 333, 362], '(PECAM)-1': [4, 169], 'is': [5, 21, 30, 38, 92, 170, 186, 195, 203, 257, 365, 380, 414, 676, 737, 1032, 1055, 2905, 2917, 3075, 3224, 3267, 3416, 3597, 3742, 3752, 3792, 3928, 4019], 'a': [6, 149, 157, 171, 314, 322, 366, 500, 600, 729, 1090, 1104, 1159, 1203, 1455, 1458, 1558, 1707, 2086, 2098, 2343, 2518, 2586, 2595, 2699, 2753, 2757, 2906, 2932, 2979, 3442, 3515, 3553, 3577, 3609, 3655, 3675, 3710, 3735, 3826, 3923, 3952, 3976, 4154, 4230, 4289, 4349], '130-kDa': [7, 172, 367], 'glycoprotein': [8, 173, 368], 'commonly': [9, 174], 'used': [10, 175, 1453, 1652, 2066, 2076, 2104, 2360, 2383], 'as': [11, 148, 176, 313, 519, 521, 715, 1103, 1229, 1344, 1374, 1419, 1454, 1497, 1614, 1783, 1907, 2044, 2125, 2230, 2265, 2550, 2662, 2752, 4296, 4348], 'an': [12, 25, 135, 177, 190, 300, 847, 1188, 2813, 3772, 3793, 3813, 3911, 3929, 3986], 'endothelium-specific': [13, 178], 'marker.': [14, 179], 'Evidence': [15, 180], 'to': [16, 69, 75, 121, 181, 234, 240, 286, 370, 382, 416, 425, 498, 508, 591, 669, 682, 724, 747, 898, 1028, 1147, 1166, 1443, 1461, 1481, 1723, 1764, 1809, 1902, 1912, 1990, 2021, 2038, 2097, 2122, 2131, 2263, 2348, 2391, 2398, 2573, 2598, 2611, 2691, 2705, 2957, 2970, 3242, 3325, 3460, 3541, 3552, 3605, 3692, 3782, 3808, 3898, 4058, 4107, 4330, 4337], 'date': [17, 182], 'suggests': [18, 183], 'that': [19, 65, 145, 184, 230, 310, 579, 1052, 1098, 1128, 1181, 2749, 2804, 2818, 2898, 2910, 2924, 3023, 3071, 3106, 3212, 3259, 3420, 3490, 3592, 3727, 3790, 4012, 4065], 'PECAM-1': [20, 53, 109, 118, 133, 146, 185, 218, 274, 283, 298, 311, 378, 413, 455, 494, 580, 604, 663, 714, 720, 744, 862, 1031, 1079, 1099, 1171, 1186, 1201, 1370, 1918, 2182, 2260, 2589, 2723, 2750, 2799, 2833, 2907, 2911, 3043, 3056, 3094, 3110, 3129, 3202, 3219, 3245, 3270, 3289, 3321, 3368, 3394, 3462, 3682, 3776, 3791, 3807, 3830, 3902, 4052, 4104, 4159, 4204, 4252, 4334, 4338], 'more': [22, 187, 726, 3566], 'than': [23, 188, 727, 1142, 3185, 3446, 3567], 'just': [24, 189, 728], 'endothelial': [26, 191, 344, 395, 433, 522, 585, 1212, 3438, 4163], 'marker': [28, 193], 'but': [29, 89, 194, 254, 1132, 2902, 3086, 3264, 3495], 'intimately': [31, 196], 'involved': [32, 197, 739, 2807], 'in': [33, 40, 98, 124, 198, 205, 263, 289, 423, 436, 503, 551, 603, 607, 679, 707, 732, 740, 857, 1082, 1092, 1161, 1173, 1226, 1279, 1324, 1396, 1412, 1445, 1457, 1490, 1567, 1602, 1606, 1814, 2095, 2184, 2302, 2466, 2512, 2517, 2524, 2528, 2695, 2698, 2808, 2828, 2836, 2847, 2874, 2890, 2967, 3032, 3196, 3235, 3250, 3273, 3288, 3392, 3455, 3480, 3511, 3527, 3536, 3545, 3595, 3654, 3658, 3669, 3678, 3706, 3747, 3764, 3794, 3803, 3816, 3820, 3829, 3913, 3931, 3955, 3994, 4016, 4038, 4073, 4113, 4161, 4214, 4219, 4233, 4245, 4251, 4293, 4318, 4321, 4344, 4362], 'signal': [34, 199, 741], 'transduction': [35, 200, 742], 'pathways.': [36, 201, 743], 'This': [37, 202, 595, 2895, 3688], 'mediated': [39, 204], 'part': [41, 206, 680], 'by': [42, 55, 207, 220, 599, 1034, 1057, 1473, 1758, 1838, 1859, 2452, 2455, 3674, 3755, 3892, 4206, 4298, 4346], 'phosphorylation': [43, 79, 111, 208, 244, 276, 749, 1060, 1095, 1144, 2345, 2966, 3027, 3074, 3131, 3204, 3223, 3366, 3395, 3778, 3832, 4054, 4160, 4254], 'of': [44, 52, 57, 153, 209, 217, 222, 318, 374, 384, 419, 428, 463, 472, 510, 515, 621, 713, 717, 861, 888, 902, 1025, 1084, 1185, 1200, 1207, 1272, 1410, 1470, 1492, 1573, 1576, 1611, 1709, 1770, 1804, 1811, 2100, 2108, 2118, 2139, 2194, 2251, 2256, 2296, 2336, 2356, 2378, 2401, 2434, 2437, 2496, 2520, 2543, 2634, 2759, 2811, 2963, 2982, 3089, 3096, 3128, 3181, 3284, 3364, 3382, 3458, 3506, 3514, 3521, 3533, 3550, 3602, 3771, 3806, 3843, 3940, 3946, 4023, 4032, 4328], 'specific': [45, 210, 889, 2980], 'tyrosine': [46, 78, 211, 243, 751, 890, 1059, 1094, 2760, 2824, 2965, 3026, 3073, 3130, 3203, 3222, 3831, 4111, 4253], 'residues': [47, 212, 752, 891, 3331, 3745, 4112], 'within': [48, 213, 892], 'the': [49, 143, 214, 308, 371, 385, 411, 460, 469, 504, 584, 588, 592, 614, 618, 711, 858, 893, 1149, 1198, 1314, 1465, 1607, 1645, 1759, 1765, 1850, 1869, 1879, 2140, 2166, 2185, 2203, 2257, 2349, 2357, 2376, 2379, 2432, 2469, 2494, 2544, 2689, 2696, 2735, 2781, 2809, 2875, 2884, 2914, 2960, 3069, 3076, 3125, 3236, 3251, 3268, 3285, 3362, 3371, 3417, 3429, 3456, 3481, 3504, 3512, 3522, 3590, 3667, 3717, 3739, 3748, 3756, 3769, 3799, 3844, 3869, 3947, 3978, 3989, 4013, 4045, 4185, 4220, 4248, 4326, 4355, 4363], 'ITAM': [50, 215, 894, 3295, 3749], 'domain': [51, 216, 853, 895, 2261, 2725, 3296], 'and': [54, 59, 97, 128, 151, 155, 219, 224, 262, 293, 316, 320, 394, 550, 587, 617, 699, 735, 904, 937, 998, 1089, 1195, 1205, 1223, 1276, 1291, 1335, 1341, 1393, 1408, 1489, 1563, 1581, 1600, 1605, 1651, 1679, 1706, 1716, 1778, 1828, 1876, 1884, 1896, 1905, 1915, 1993, 2008, 2023, 2040, 2069, 2084, 2103, 2112, 2137, 2197, 2210, 2222, 2227, 2316, 2375, 2418, 2424, 2461, 2488, 2500, 2526, 2539, 2582, 2594, 2609, 2617, 2631, 2659, 2693, 2756, 2783, 2788, 2800, 2869, 2909, 2929, 2938, 3173, 3246, 3272, 3432, 3437, 3611, 3700, 3730, 3751, 3779, 3802, 3822, 3840, 3875, 3920, 3937, 3983, 4003, 4026, 4055, 4070, 4158, 4320, 4335], 'recruitment': [56, 221, 901, 1083, 1184], 'adapter': [58, 223, 903], 'signaling': [60, 225, 905], 'molecules.': [61, 226, 377, 906], 'Recently': [62, 227], 'we': [63, 82, 228, 247, 1050, 1125, 2791, 2816, 3518, 3811, 4359], 'demonstrated': [64, 229, 746, 4354], 'PECAM-1/β-catenin': [66, 231, 1053, 2819], 'association': [67, 232, 1054, 2831, 2844, 2882, 3041, 3054, 3535, 3660, 3680, 3915, 4216, 4235], 'functions': [68, 147, 233, 312, 2751], 'regulate': [70, 235], 'β-catenin': [71, 77, 236, 242, 1035, 1058, 1085, 1093, 1105, 2762, 2787, 2823, 2830, 2901, 3053, 3072, 3239, 3266, 3476, 3497, 3679, 3729], 'localization': [72, 237, 1163], 'and,': [73, 238, 422, 1178, 3786], 'moreover,': [74, 239, 1179, 3787], 'modulate': [76, 241], 'levels.': [80, 245], 'Here': [81, 246, 1124], 'show': [83, 248], 'that:': [84, 249], '1)': [85, 250], 'not': [86, 251, 1129, 2899, 3265, 3377, 3410, 3496, 3582, 3753], 'only': [87, 252, 1130, 2900, 3478], 'β-catenin,': [88, 253, 2226, 2928], 'also': [90, 255, 1133, 2903], 'γ-catenin': [91, 115, 120, 130, 256, 280, 285, 295, 1134, 1162, 1182, 2228, 2789, 2794, 2904, 2964, 3025, 3097, 3107, 3209, 3214, 3231, 3263, 3459, 3494, 3670, 3708, 3731, 3785, 3893, 4207, 4329], 'associated': [93, 258, 3900, 4332], 'with': [94, 114, 259, 279, 524, 1030, 1136, 1286, 1330, 1402, 1660, 1671, 1833, 1849, 1868, 1873, 1878, 2202, 2214, 2224, 2293, 2332, 2342, 2363, 2449, 2468, 2478, 2482, 2490, 2509, 2577, 2605, 2645, 2655, 2719, 2798, 2822, 2832, 2840, 2913, 2972, 2977, 3042, 3055, 3082, 3093, 3109, 3115, 3135, 3145, 3187, 3244, 3275, 3387, 3406, 3428, 3469, 3499, 3681, 3784, 3825, 3901, 3985, 4121, 4247, 4333], 'PECAM-1in': [95, 260], 'vitro': [96, 261, 437, 530, 3765, 3804, 4048], 'vivo;': [99, 264], '2)': [100, 265], 'PKC': [101, 266, 2022, 2025, 2344, 2731, 3389, 3421, 3491, 3507, 3543, 3555, 3579, 3593, 3613, 3796, 3957, 3965, 4156, 4294, 4300, 4307, 4347], 'enzyme': [102, 267, 2338, 3147, 3390], 'directly': [103, 268, 3423], 'phosphorylates': [104, 269], 'purified': [105, 270, 2333, 3137, 3388], 'PECAM-1;': [106, 271], '3)': [107, 272], 'PKC-derived': [108, 273, 3430], 'serine/threonine': [110, 275, 3365, 3777, 4053, 4339], 'inversely': [112, 277], 'correlates': [113, 278], 'association;': [116, 281], '4)': [117, 282], 'recruits': [119, 284], 'cell-cell': [122, 287, 417, 1087, 1167], 'junctions': [123, 288, 1088, 1168], 'transfected': [125, 290, 1343, 2201, 2848], 'SW480': [126, 291, 1174, 1363, 2196, 2637], 'cells;': [127, 292], '5)': [129, 294], 'may': [131, 296, 3111, 3538, 3732, 3788], 'recruit': [132, 297], 'into': [134, 299, 1086, 1187, 1681], 'insoluble': [136, 301, 1717], 'cytoskeletal': [137, 302, 1190], 'fraction.': [138, 303, 1191], 'These': [139, 304, 907, 1192, 4041], 'data': [140, 305], 'further': [141, 306, 597, 1196, 2958, 3123, 3502, 3588, 3690, 4043], 'support': [142, 307, 3691, 3768, 4044], 'concept': [144, 309, 1199, 3070, 3591, 3770], 'binder': [150, 315, 1204], 'modulator': [152, 317, 1106, 1206, 2758], 'catenins': [154, 319, 2916, 2926, 3757], 'provides': [156, 321], 'molecular': [158, 323, 3374], 'mechanism': [159, 324, 1152], 'for': [160, 325, 1154, 1483, 1583, 1653, 1663, 1853, 2067, 2077, 2218, 2320, 2361, 2367, 2384, 2428, 2445, 2627, 2648, 2652, 2707, 2729, 2755, 2936, 3079, 3132, 3226, 3367, 3713, 3734, 3889, 3988, 4203], 'previously': [161, 326, 1499, 1922, 4256], 'reported': [162, 327, 1051, 2748, 2923, 4064, 4257], 'PECAM-1/cytoskeleton': [163, 328], 'interactions.': [164, 329], 'platelet-endothelial': [330], 'immunoreceptor': [334, 848], 'tyrosine-based': [335, 849, 3294], 'activation': [336, 850], 'motif': [337, 851], 'SH-2-containing': [338, 909], 'protein-tyrosine': [339, 910], 'phosphatase': [340, 911], 'human': [341, 1307, 1364, 1913, 2181], 'umbilical': [342, 1210], 'vein': [343, 1211], 'cell(s)': [345], 'post': [346], 'coitus': [347], 'protein': [348, 352, 1754, 1772, 1779, 1806, 1839, 1860, 2328, 2389, 3118, 3140, 3386, 3436], 'kinase': [349, 353, 2298, 2303, 2984], 'C': [350, 3199, 3697], 'mitogen-activated': [351], 'glutathione': [354], 'S-transferase': [355], 'immunoprecipitation': [356], '4-amino-5-(4': [357], 'methylphenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine': [358], '(PECAM-1,': [363], 'CD31)1': [364], 'belonging': [369], 'Ig': [372], 'superfamily': [373], 'expression': [379, 1172, 2186, 2193, 3966, 4308], 'restricted': [381], 'cells': [383, 396, 474, 586, 1177, 1213, 1265, 1310, 1321, 1367, 1463, 1471, 2199, 2211, 2685, 2838, 2850, 3604, 4164], 'vascular': [386, 615], 'system': [387], 'platelets,': [388], 'monocytes,': [389], 'neutrophils,': [390, 518], 'selected': [391, 2213], 'T': [392], 'cells,': [393, 523, 2638], '(1.Newman': [397], 'P.J.': [398, 804, 946, 3333], 'J.': [399, 446, 483, 539, 635, 654, 701, 705, 766, 805, 829, 871, 921, 947, 1007, 1042, 1069, 1115, 1239, 1254, 1294, 1296, 1354, 1384, 1427, 1511, 1529, 1627, 1734, 1741, 1791, 1955, 1973, 2240, 2275, 2560, 2672, 2771, 2860, 3003, 3157, 3305, 3347, 3350, 3640, 3641, 3859, 4088, 4135, 4176, 4269], 'Clin.': [400], 'Invest.': [401, 1300, 2175], '1997;': [402, 769, 808, 832, 874, 950, 1044, 1513, 1957, 2278, 2948, 3160, 3308, 3861], '99:': [403], '3-8Crossref': [404], 'PubMed': [405, 452, 489, 545, 573, 792, 816, 840, 882, 932, 958, 993, 1018, 1075, 1121, 1245, 1260, 1360, 1390, 1433, 1539, 1637, 1747, 1797, 1939, 1983, 2158, 2246, 2286, 2566, 2678, 2777, 2866, 2951, 3014, 3168, 3316, 3356, 3650, 4098, 4145, 4279], 'Scopus': [406, 490, 546, 574, 793, 817, 841, 883, 933, 959, 994, 1019, 1540, 1638, 1748, 1940, 1984, 2159, 2287, 2952, 3015, 3169, 3317, 3357, 4099, 4146, 4280], '(432)': [407], 'Google': [408, 453, 492, 548, 576, 659, 772, 795, 819, 843, 885, 935, 961, 996, 1021, 1047, 1076, 1122, 1246, 1261, 1304, 1361, 1391, 1434, 1516, 1542, 1640, 1750, 1798, 1942, 1960, 1986, 2161, 2179, 2247, 2289, 2567, 2679, 2778, 2867, 2954, 3017, 3171, 3319, 3359, 3651, 3864, 4101, 4148, 4181, 4282], 'Scholar).': [409, 454, 493, 660, 886, 1022, 1048, 1077, 1123, 1262, 1305, 1362, 1435, 1543, 1641, 1751, 1799, 1987, 2248, 2568, 2680, 2779, 2955, 3018, 3360, 3865, 4102, 4149, 4182, 4283], 'In': [410, 661, 3051, 3467, 3599, 3715, 4228, 4284], 'latter,': [412], 'localized': [415], 'borders': [418], 'confluent': [420], 'monolayers': [421], 'addition,': [424, 662, 4285], 'lumen-facing': [426], 'areas': [427], 'blood': [429, 3934], 'vessels': [430], 'or': [431, 467, 517, 774, 1609, 2129, 2163, 2366, 2636, 3189, 3218, 3373, 3878, 4193], 'tube-like': [432], 'structures': [434], 'formed': [435], '(2.Ilan': [438, 1061, 1107, 1231, 1346, 1376, 2232, 2552, 2664, 2763], 'N.': [439, 760, 1062, 1108, 1232, 1249, 1347, 1377, 1422, 1786, 2233, 2553, 2665, 2764, 2853], 'Mahooti': [440, 1063, 1109, 1233, 1250, 1348, 1378, 1423, 1520, 1618, 1787, 1964, 2234, 2554, 2666, 2765, 2854, 4079, 4126, 4260], 'P.': [441, 693, 1041, 1064, 1110, 1234, 1349, 1379, 2235, 2555, 2667, 2766, 2855, 3618, 3622, 3630], 'Rimm': [442, 1065, 1111, 1235, 1350, 1380, 2236, 2556, 2668, 2767, 2856], 'D.L.': [443, 1066, 1112, 1236, 1351, 1381, 2237, 2557, 2669, 2768, 2857], 'Madri': [444, 479, 780, 869, 1067, 1113, 1237, 1252, 1352, 1382, 1425, 1508, 1526, 1624, 1789, 1927, 1952, 1970, 2146, 2172, 2238, 2273, 2558, 2670, 2769, 2858, 3155, 3303, 3856, 4085, 4132, 4266], 'J.A.': [445, 480, 781, 870, 1068, 1114, 1238, 1253, 1353, 1383, 1426, 1509, 1527, 1625, 1790, 1928, 1953, 1971, 2147, 2173, 2239, 2274, 2559, 2671, 2770, 2859, 3156, 3304, 3857, 4086, 4133, 4267], 'Cell': [447, 767, 1070, 1116, 1240, 1255, 1355, 1385, 1428, 1656, 1742, 1792, 2241, 2561, 2673, 2772, 2861, 3351], 'Sci.': [448, 785, 1071, 1117, 1241, 1256, 1356, 1386, 1429, 1793, 1932, 2151, 2242, 2562, 2674, 2773, 2862], '1999;': [449, 656, 990, 1072, 1118, 1242, 1357, 1387, 1531, 1629, 1975, 2243, 2563, 2675, 2774, 2863, 4090, 4137, 4271], '112:': [450, 1073, 1119, 1243, 1358, 1388, 2244, 2564, 2676, 2775, 2864], '3005-3014Crossref': [451, 1074, 1120, 1244, 1359, 1389, 2245, 2565, 2677, 2776, 2865], 'becomes': [456], 'diffusely': [457], 'distributed': [458], 'on': [459, 582, 750, 1775, 1856, 2426, 2443, 2640, 2688, 3208, 3329, 3449, 3508, 3570, 3759, 4110, 4189], 'surface': [462], 'sparse': [464], 'cultures': [466, 1657, 2124, 2506], 'at': [468, 677, 1596, 1666, 2105, 2134, 2323, 2716, 3370, 3872, 3903, 4342], 'leading': [470, 507], 'fronts': [471], 'migrating': [473, 2682], '(3.Schimmenti': [475], 'L.A.': [476], 'Yan': [477, 557, 778, 1925, 2144], 'H.-C.': [478], 'Albelda': [481, 567], 'S.M.': [482, 568], 'Cell.': [484], 'Physiol.': [485, 4177], '1992;': [486, 3353], '153:': [487], '417-428Crossref': [488], '(112)': [491], 'has': [495, 721, 2921, 3376], 'been': [496, 667, 722, 1920, 2922, 3379, 3835], 'shown': [497, 723, 3195], 'be': [499, 725, 1148, 2806, 3326, 3539, 3899, 4108, 4331], 'key': [501], 'player': [502, 731], 'cascade': [506], 'extravasation': [509], 'leukocytes': [511, 589, 609], 'during': [512, 3925, 4029], 'inflammation.': [513], 'Pretreatment': [514], 'monocytes': [516], 'well': [520], 'anti-PECAM-1': [525, 2003], 'antibodies': [526, 1911, 1989, 2012, 2020, 2037, 2055, 2229, 2365, 2593, 2621], 'effectively': [527], 'inhibited': [528], 'transmigrationin': [529], '(4.Muller': [531], 'W.A.': [532, 647], 'Weigel': [533], 'S.A.': [534, 631], 'Deng': [535], 'X.': [536], 'Phillips': [537], 'D.M.': [538], 'Exp.': [540], 'Med.': [541], '1993;': [542, 570], '178:': [543], '449-460Crossref': [544], '(987)': [547], 'Scholar)': [549, 773, 844, 936, 1392, 2162], 'vivo': [552, 3144, 3795, 3801, 4322], '(5.Vaporciyan': [553], 'A.A.': [554], 'DeLisser': [555], 'H.M.': [556], 'H.': [558, 629, 633, 3620], 'Mendiguren': [559], 'I.I.': [560], 'Thom': [561], 'S.R.': [562], 'Jones': [563], 'M.L.': [564], 'Ward': [565, 799, 941], 'P.A.': [566, 3002], 'Science.': [569], '262:': [571], '1580-1582Crossref': [572], '(430)': [575], 'Scholar),': [577, 709, 962, 997, 2290, 3320, 3652], 'indicating': [578], 'molecules': [581], 'both': [583], 'contribute': [590], 'transmigration': [593], 'process.': [594], 'was': [596, 745, 854, 1145, 1417, 1452, 1495, 1756, 1781, 1847, 1893, 2329, 2359, 2396, 2459, 2548, 2727, 2834, 2845, 3057, 3141, 3232, 3240, 3247, 3322, 3404, 3477, 3672, 3896, 3981, 4105, 4217, 4236, 4310], 'supported': [598], 'genetic': [601], 'approach': [602], 'knockout': [605, 664], 'mice,': [606], 'which': [608, 675, 3707, 3926], 'are': [610, 2931, 4036], 'transiently': [611, 1342], 'arrested': [612], 'between': [613, 2786, 3775, 3837, 3917, 4000, 4051], 'endothelium': [616], 'basement': [619], 'membrane': [620, 3980], 'inflammatory': [622], 'sites': [623, 2733], '(6.Duncan': [624], 'G.S.': [625], 'Andrew': [626], 'D.P.': [627], 'Takimoto': [628], 'Kaufman': [630], 'Yoshida': [632], 'Spellberg': [634], 'de': [636], 'la': [637], 'Pompa': [638], 'J.L.': [639], 'Elia': [640], 'A.': [641, 643, 702, 788, 1740, 1935, 2154, 3530], 'Wakeham': [642], 'Karan-Tamir': [644], 'B.': [645, 1738, 4040], 'Muller': [646], 'Senaldi': [648], 'G.': [649], 'Zukowski': [650], 'M.M.': [651], 'Mak': [652], 'T.W.': [653], 'Immunol.': [655, 1043], '162:': [657], '3022-3030PubMed': [658], 'mice': [665, 1551], 'have': [666, 1919, 3834, 4062, 4152], 'noted': [668, 3897, 4218], 'suffer': [670], 'from': [671, 1164, 1217, 1268, 1313, 1464, 1548, 1997, 2015, 2029, 2048, 3292, 3868, 3882], 'prolonged': [672], 'bleeding': [673], 'times,': [674], 'least': [678, 2717, 4343], 'due': [681, 3540], 'disrupted': [683], 'endothelial-platelet': [684], 'interactions': [685, 734, 2820, 3108, 3114, 3498, 3510, 3562, 3585], '(53.Mahooti,': [686], 'S.,': [687, 691], 'Graesser,': [688], 'D.,': [689], 'Patel,': [690], 'Newman,': [692], 'J.,': [694], 'Duncan,': [695], 'G.,': [696], 'Mak,': [697], 'T.,': [698], 'Madri,': [700], '(2000)': [703], 'Am.': [704, 1510, 1528, 1626, 1954, 1972, 3858, 4087, 4134, 4175, 4268], 'Pathol.,': [706], 'pressGoogle': [708], 'supporting': [710, 3068, 3589], 'role': [712, 2962, 3127, 3363, 3505], 'mediator': [716], 'adhesion/activation.': [719], 'passive': [730], 'adhesive': [733], 'indeed': [736], 'actively': [738], 'undergo': [748], 'following': [753], 'mechanical': [754], '(7.Osawa': [755], 'M.': [756, 758, 826, 866, 985, 1503, 1730, 1947, 2270, 3152, 3300, 3626, 3851], 'Masuda': [757], 'Harada': [759], 'Lopes': [761], 'R.B.': [762], 'Fujiwara': [763], 'K.': [764, 822, 1039], 'Eur.': [765], 'Biol.': [768, 806, 830, 872, 922, 948, 1008, 1743, 2276, 3004, 3158, 3306, 3352, 3642], '72:': [770], '229-237PubMed': [771], 'biochemical': [775, 1654], '(8.Lu': [776, 1923, 2142], 'T.T.': [777, 864, 1924, 2143, 2268, 3150, 3298], 'L.G.': [779, 1926, 2145], 'Proc.': [782, 1929, 2148], 'Natl.': [783, 1930, 2149], 'Acad.': [784, 1931, 2150], 'U.': [786, 1933, 2152], 'S.': [787, 868, 971, 1251, 1424, 1521, 1619, 1788, 1934, 1965, 2153, 2272, 3154, 3302, 4080, 4127, 4261], '1996;': [789, 1936, 2155, 3006, 4178], '93:': [790, 1937, 2156], '11808-11813Crossref': [791, 1938, 2157], '(97)': [794, 1941, 2160], 'Scholar,': [796, 820, 1247, 1517, 1943, 1961], '9.Jackson': [797], 'D.E.': [798, 920, 940], 'C.M.': [800, 942], 'Wang': [801, 943, 1522, 1620, 1966, 2170, 4081, 4128, 4262], 'R.': [802, 944, 1298, 3337], 'Newman': [803, 945], 'Chem.': [807, 831, 873, 923, 949, 1009, 2277, 3005, 3159, 3307, 3643], '272:': [809, 833, 875, 951, 2279, 3161, 3309], '6986-6993Abstract': [810, 952], 'Full': [811, 813, 835, 837, 877, 879, 927, 929, 953, 955, 1013, 1015, 1534, 1536, 1632, 1634, 1978, 1980, 2281, 2283, 3009, 3011, 3163, 3165, 3311, 3313, 3647, 4093, 4095, 4140, 4142, 4274, 4276], 'Text': [812, 814, 836, 838, 878, 880, 928, 930, 954, 956, 1014, 1016, 1535, 1537, 1633, 1635, 1979, 1981, 2282, 2284, 3010, 3012, 3164, 3166, 3312, 3314, 3648, 4094, 4096, 4141, 4143, 4275, 4277], 'PDF': [815, 839, 881, 931, 957, 1017, 1538, 1636, 1982, 2285, 3013, 3167, 3315, 3649, 4097, 4144, 4278], '(199)': [818, 960], '10.Sagawa': [821], 'Kimura': [823], 'T.': [824, 1037, 1505, 1949, 2171, 3624, 3853], 'Swieter': [825], 'Siraganian': [827], 'R.P.': [828], '31086-31091Abstract': [834], '(94)': [842], 'stimulation.': [845], 'Specifically,': [846], '(ITAM)': [852], 'recently': [855, 2747, 4063], 'identified': [856], 'cytoplasmic': [859, 2259, 2724], 'tail': [860], '(11.Lu': [863, 2267, 3297], 'Barreuther': [865, 1502, 1946, 2269, 3151, 3299, 3850], 'Davis': [867, 2271, 3153, 3301], '14442-14446Abstract': [876, 2280, 3162, 3310], '(91)': [884, 2288, 3170, 3318], 'Phosphorylation': [887], 'were': [896, 1215, 1224, 1266, 1277, 1311, 1322, 1372, 1394, 1441, 1478, 1546, 1565, 1588, 1594, 1648, 1658, 1720, 1773, 1807, 1864, 1900, 1995, 2013, 2027, 2046, 2093, 2120, 2189, 2200, 2212, 2291, 2382, 2441, 2464, 2475, 2507, 2532, 2571, 2601, 2643, 2686, 2703, 2714, 2975, 3029, 3091, 3184, 3887, 3968, 3998, 4201, 4360], 'found': [897, 1027, 1146, 2817, 4106], 'mediate': [899, 3112], 'selective': [900, 3612], 'include': [908], '(SHP)-1': [912], '(12.Hua': [913], 'C.T.': [914], 'Gamble': [915], 'J.R.': [916], 'Vadas': [917], 'M.A.': [918], 'Jackson': [919], '1998;': [924, 1010, 1257, 1430, 1744, 1794, 2176], '273:': [925, 1011], '28332-28340Abstract': [926], '(116)': [934], '-2': [938], '(9.Jackson': [939], 'SHIP,': [963], 'phospholipase': [964], 'C-γ': [965], '(13.Pumphrey': [966], 'N.J.': [967], 'Taylor': [968], 'V.': [969, 3628, 4166, 4174], 'Freeman': [970], 'Douglas': [972], 'M.R.': [973, 1006], 'Bradfield': [974], 'P.F.': [975], 'Young': [976], 'S.P.': [977], 'Lord': [978], 'J.M.': [979, 2943], 'Wakelam': [980], 'M.J.O.': [981], 'Bird': [982], 'I.N.': [983], 'Salmon': [984], 'Buckley': [986], 'C.D.': [987], 'FEBS': [988], 'Lett.': [989], '450:': [991], '77-83Crossref': [992], '(92)': [995], 'phosphoinositide': [999], '3-kinase': [1000], '(14.Pellegatta': [1001], 'F.': [1002, 3634], 'Chierchia': [1003], 'S.L.': [1004], 'Zocchi': [1005], '27768-27771Abstract': [1012], '(76)': [1020], 'Another': [1023], 'set': [1024], 'proteins': [1026], 'associate': [1029, 2797, 2971, 3783], 'represented': [1033], '(15.Matsumura': [1036], 'Wolff': [1038], 'Petzelbauer': [1040], '158:': [1045], '3408-3416PubMed': [1046], 'Recently,': [1049], 'regulated': [1056], 'Moreover,': [1078, 4103], 'overexpression': [1080], 'resulted': [1081, 3391, 3653], 'decrease': [1091, 3444, 3677, 3828, 3954, 4015, 4213], 'levels,': [1096], 'suggesting': [1097, 3105, 3211, 3258, 3489, 3726, 4011], 'plays': [1100], 'active': [1101], 'roles': [1102], 'present': [1126, 3234], 'evidence': [1127, 3419], 'β-': [1131], 'associates': [1135], 'PECAM-1.': [1137, 3083, 3425, 3500, 3714, 3760], 'Interestingly,': [1138, 2873, 3084, 3229, 3666, 3943], 'however,': [1139], 'serine/threonine,': [1140], 'rather': [1141], 'tyrosine,': [1143], 'major': [1150, 2933, 3077, 3269, 4350], 'regulatory': [1151, 4351], 'responsible': [1153], 'PECAM-1/γ-catenin': [1155, 2881, 3534, 3561, 3584, 3659, 3914, 4024, 4190, 4215, 4356], 'association.': [1156], 'We': [1157, 2745, 4061], 'demonstrate': [1158], 'shift': [1160], 'nuclear': [1165], 'upon': [1169], 'stable': [1170, 2192], 'colon': [1175, 1365], 'carcinoma': [1176, 1366], 'suggest': [1180, 2897], 'mediates': [1183], 'insoluble,': [1189], 'results': [1193], 'confirm': [1194, 4325], 'expand': [1197], 'being': [1202, 2888], 'catenins.': [1208], 'Human': [1209], '(HUVEC)': [1214], 'obtained': [1216, 1267, 1312], 'Jordan': [1218], 'Pober': [1219], '(Yale': [1220], 'Medical': [1221], 'School)': [1222], 'cultured': [1225, 1601, 4074, 4162], 'gelatin-coated': [1227], 'flasks': [1228], 'described': [1230, 1345, 1375, 1420, 1498, 1615, 1784, 1921, 2231, 2266, 2551, 2663], '16.Ilan': [1248], '111:': [1258, 1431, 1795], '3621-3631Crossref': [1259, 1432, 1796], 'Hemangioendothelioma': [1263], '(EOMA)': [1264], 'Robert': [1269], 'Auerbach': [1270, 1297], '(University': [1271], 'Wisconsin,': [1273], 'Madison,': [1274], 'WI)': [1275], 'grown': [1278, 1323, 1395, 1442, 2639, 2687], 'complete': [1280], "Dulbecco's": [1281, 1325, 1397], 'modified': [1282, 1326, 1398], "Eagle's": [1283, 1327, 1399], 'medium': [1284, 1328, 1400], 'supplemented': [1285, 1329, 1401, 1872, 2481], '10%': [1287, 1331, 1403, 2314, 2578], 'fetal': [1288, 1332, 1404], 'bovine': [1289, 1333, 1405, 2421], 'serum': [1290, 1334, 1604, 1836, 2422, 2581], 'antibiotics': [1292], '(17.Obeso': [1293], 'Weber': [1295], 'Lab.': [1299, 2174], '1990;': [1301], '63:': [1302], '259-269PubMed': [1303], 'MCF7': [1306, 2849], 'breast': [1308], 'adenocarcinoma': [1309], 'American': [1315], 'Type': [1316], 'Culture': [1317], 'Collection': [1318], '(HTB-22).': [1319], 'The': [1320, 1844, 2457, 2472, 2722], '10': [1336, 2249, 2309, 2312, 2429], 'μg/ml': [1337], 'insulin': [1338], '(bovine;': [1339], 'Sigma)': [1340, 2065], 'stably': [1368], 'expressing': [1369], 'cDNA': [1371, 2183], 'generated': [1373], 'serum.': [1406], 'Embedding': [1407], 'culturing': [1409], 'HUVEC': [1411, 1440, 2438, 2504, 2635, 2891, 2974, 3035, 3182, 3537, 3551, 3596], 'three-dimensional': [1413, 2505], 'type-I': [1414], 'collagen': [1415], 'gels': [1416], 'performed': [1418, 1496, 1782, 3186], '(16.Ilan': [1421, 1785], 'For': [1436, 1590, 1800, 2191, 2681], 'migration': [1438], 'assays,': [1439], 'confluency': [1444, 2692], '100-mm': [1446], 'dishes.': [1447], 'A': [1448, 4211], '15-well': [1449], 'minigel': [1450], 'comb': [1451], 'rake': [1456], 'circular': [1459], 'pattern': [1460], 'scrape': [1462], 'dish': [1466], 'leaving': [1467], 'concentric': [1468], 'rings': [1469], 'separated': [1472, 1566], 'intermittent': [1474], 'cell-free': [1475], 'regions.': [1476], 'Cells': [1477, 2702], 'then': [1479, 1894, 2602], 'allowed': [1480, 2704], 'migrate': [1482, 2706], '2': [1484, 1854, 1994, 2010, 2708, 3397, 3453, 3485, 3564, 3574, 3662, 3684, 3723], 'days': [1485, 2709, 3838, 3873, 3918, 4001], 'before': [1486, 2431, 2493, 2710], 'analyzed.': [1487, 1589], 'Harvesting': [1488], 'vitroculturing': [1491], 'murine': [1493, 3846, 4033, 4075], 'conceptuses': [1494, 1545, 1580, 1587, 4034, 4076], '(22.Pinter': [1500, 3848], 'E.': [1501, 1519, 1617, 1736, 1945, 1963, 3632, 3849, 4078, 4125, 4259], 'Lu': [1504, 1948, 3852], 'Imhof': [1506, 1524, 1622, 1950, 1968, 3854, 4083, 4130, 4264], 'B.A.': [1507, 1525, 1623, 1951, 1969, 3000, 3855, 4084, 4131, 4265], 'Pathol.': [1512, 1530, 1628, 1956, 1974, 3860, 4089, 4136, 4270], '150:': [1514, 1958, 3862], '1523-1530PubMed': [1515, 1959, 3863], '23.Pinter': [1518, 1962], 'Y.': [1523, 1621, 1967, 4082, 4129, 4168, 4263], '154:': [1532, 1630, 1976, 4091, 4138, 4272], '1367-1379Abstract': [1533, 1631, 1977, 4092, 4139, 4273], '(54)': [1541, 1639, 1985, 4100, 4147, 4281], 'Briefly,': [1544, 2569], 'collected': [1547, 1595], 'timed': [1549], 'pregnant': [1550], '(CD1,': [1552], 'Charles': [1553], 'River,': [1554], 'Wilmington,': [1555], 'MA)': [1556], 'using': [1557, 2370, 2585, 2734], 'dissecting': [1559], 'microscope.': [1560], 'Yolk': [1561], 'sacs': [1562, 1647, 4119], 'embryos': [1564, 1575, 1593, 3886, 4123], 'day': [1568, 1577, 1584, 1597, 3883, 4115, 4195], '9.5': [1569, 1585, 3841, 3884, 3921, 4116, 4196], 'p.c.': [1570, 1579, 1586, 1599, 3842, 3877, 3885, 4005, 4117, 4197], 'specimens.': [1571], 'Groups': [1572], '50–60': [1574], '7.5': [1578, 1598, 3839, 3874, 3919, 4002], '15': [1582, 1664], 'glucose': [1591, 4187, 4239, 4286], 'treatment,': [1592], 'rat': [1603], 'absence': [1608], 'presence': [1610], '25': [1612], 'mmd-glucose': [1613], '(23.Pinter': [1616, 4077, 4124, 4258], 'After': [1642], '48': [1643], 'h,': [1644, 2629], 'yolk': [1646, 3879, 3932, 4068, 4118, 4198], 'separated,': [1649], 'lysed,': [1650], 'studies.': [1655], 'pretreated': [1659], '1': [1661, 1676, 1700, 1703, 1992, 2334, 2399, 2628, 2653, 2871, 2893, 3037, 3047, 3064, 3101, 3175, 3198, 3216, 3474, 3529, 3696, 3703], 'mmorthovanadate': [1662], 'min': [1665, 2322, 2430, 2654], '37': [1667], '°C,': [1668], 'washed': [1669, 1865, 2476, 2604], 'twice': [1670, 2477, 2718], 'ice-cold': [1672], 'phosphate-buffered': [1673, 2513], 'saline': [1674, 2514], 'containing': [1675, 1816], 'mm': [1677, 1685, 1690, 1701, 1818, 1826, 1889, 2102, 2310, 2405, 2410, 2413], 'orthovanadate': [1678], 'scraped': [1680, 2694], 'lysis': [1682], 'buffer': [1683, 1815, 1871, 1881, 1892, 2304, 2403, 2480, 2492], '(50': [1684, 1888, 2404], 'Tris,': [1686, 1819, 2406], 'pH': [1687, 1820, 2307, 2407], '7.4,': [1688, 2308], '150': [1689, 2409], 'NaCl,': [1691, 1824, 2411], '1%': [1692, 1695], 'Triton': [1693, 2657], 'X-100,': [1694, 2658], 'Nonidet': [1696, 1830, 2416], 'P-40,': [1697, 1831, 2417], '0.5%': [1698, 1829, 2415, 2656], 'deoxycholate,': [1699], 'orthovanadate,': [1702], 'mmphenylmethylsulfonyl': [1704], 'fluoride,': [1705], 'mixture': [1708], 'proteinase': [1710], 'inhibitors;': [1711], 'Roche': [1712], 'Molecular': [1713, 2208], 'Biochemicals).': [1714], 'Soluble': [1715], 'fractions': [1719, 3483], 'made': [1721, 3867], 'according': [1722, 1763, 2347], 'Simcha': [1724], 'et': [1725], 'al.': [1726], '(49.Simcha': [1727], 'I.': [1728], 'Shtutman': [1729], 'Salomon': [1731], 'D.': [1732, 3616, 3638, 4172], 'Zhurinsky': [1733], 'Sadot': [1735], 'Geiger': [1737], "Ben-Ze'ev": [1739], '141:': [1745], '1433-1448Crossref': [1746], '(236)': [1749], 'Total': [1752], 'cellular': [1753, 1771, 1805, 3372], 'concentration': [1755, 1887, 2099], 'determined': [1757], 'BCA': [1760], 'assay': [1761], '(Pierce)': [1762], "manufacturer's": [1766, 2350], 'instructions.': [1767, 2354], '20': [1768, 2321, 2462, 2649], 'μg': [1769, 1803, 2436], 'fractionated': [1774], 'SDS-polyacrylamide': [1776, 2501], 'gels,': [1777], 'immunoblotting': [1780, 2068, 2362, 4208, 4301], 'immunoprecipitation,': [1801], '100': [1802, 2435], 'brought': [1808], 'volume': [1810], '1.0': [1812], 'ml': [1813, 2400], '50': [1817], '7.5,': [1821, 2408], '0.4': [1822, 2483], 'm': [1823, 2484], '5': [1825, 2101, 2113, 2412], 'EDTA,': [1827, 2414], 'preabsorbed': [1832], 'normal': [1834, 2579], 'rabbit': [1835], 'followed': [1837, 1858, 2454, 3891, 4205], 'A/G-Sepharose': [1840, 1861], '(Santa': [1841], 'Cruz)': [1842, 2592], 'precipitation.': [1843], 'cleared': [1845, 2523], 'supernatant': [1846, 2458, 3252, 3482], 'incubated': [1848, 2292, 2425, 2442], 'appropriate': [1851], 'antibody': [1852, 2597, 3987], 'h': [1855], 'ice': [1857, 2427, 2444], 'immunoprecipitation.': [1862], 'Beads': [1863], 'three': [1866], 'times': [1867], 'same': [1870, 1880, 2876, 3948, 3979], '5%': [1874], 'sucrose': [1875, 1883], 'once': [1877, 2489], 'without': [1882], 'reduced': [1885, 3031], 'salt': [1886], 'NaCl).': [1890], 'Sample': [1891], 'added,': [1895], 'after': [1897, 3060, 4238], 'boiling,': [1898, 2499], 'samples': [1899, 3950, 4200, 4222], 'subjected': [1901, 2572, 2610], 'gel': [1903, 2502], 'electrophoresis': [1904], 'immunodetection': [1906], 'described.': [1908], 'Rabbit': [1909], 'polyclonal': [1910], '(BooBoo),': [1914], 'mouse': [1916], '(Sleet)': [1917], '22.Pinter': [1944], 'Polyclonal': [1988, 2019], 'desmoplakin': [1991, 3090], 'purchased': [1996, 2014, 2028, 2047], 'Serotec': [1998], '(Oxford,': [1999], 'UK).': [2000], 'Anti-phosphotyrosine': [2001], '(PY99),': [2002], '(C-20),': [2004], 'anti-phosphorylated': [2005], 'MAPK': [2006, 3996], '(E-4),': [2007], 'anti-Erk': [2009], '(C14)': [2011], 'Santa': [2016, 2591], 'Cruz': [2017], 'Biotechnology.': [2018], 'phospho': [2024, 3956], '(pan)': [2026], 'Upstate': [2030], 'Biotechnology,': [2031, 2300, 2352], 'Inc.': [2032], '(Lake': [2033], 'Placid,': [2034], 'NY).': [2035], 'Monoclonal': [2036], 'β−catenin': [2039], 'SHP-2': [2041], '(also': [2042], 'known': [2043], 'PTP1D)': [2045], 'Transduction': [2049], 'Laboratories': [2050, 2074], '(Lexington,': [2051], 'KY).': [2052], 'Other': [2053, 4150], 'monoclonal': [2054, 2596], 'included': [2056], 'anti-vimentin': [2057], '(clone': [2058, 2063, 2071], 'Vim': [2059], '3B4,': [2060], 'Dako),': [2061], 'anti-γ-catenin': [2062, 2070], '15F11,': [2064], 'PG-11E4,': [2072], 'Zymed': [2073], 'Inc.)': [2075, 2301, 2341, 2353], 'immunostaining.': [2078], 'PP1,': [2079, 2978], 'bisindolylmaleimide': [2080, 3606], 'GF': [2081], '109203x,': [2082], 'staurosporine,': [2083], '1,2-dioctanoyl-sn-glycerol,': [2085], 'diacylglycerol': [2087, 3557], 'analog': [2088], '(Calbiochem,': [2089], 'La': [2090], 'Jolla,': [2091], 'CA),': [2092], 'dissolved': [2094], 'Me2SO': [2096, 2119], 'final': [2106], 'concentrations': [2107], '1,': [2109, 2110], '0.1,': [2111], 'μm,': [2114], 'respectively.': [2115], 'Matching': [2116], 'volumes': [2117], 'added': [2121, 2397], 'controls.': [2126], 'Wild': [2127], 'type': [2128], 'Tyr': [2130], 'Phe': [2132], 'mutations': [2133], 'Tyr663,': [2135], 'Tyr686,': [2136], 'Tyr701': [2138], 'full-length': [2141], 'truncated': [2164], '(lacking': [2165], 'ectodomain': [2167], '(41.Kim': [2168], 'C.S.': [2169], '78:': [2177], '583-590PubMed': [2178], 'Scholar))': [2180], 'vector': [2187], 'pcDNA3': [2188], 'used.': [2190], 'PECAM-1,': [2195, 2973, 3890], '293': [2198], 'FuGENE': [2204], '6': [2205], 'reagent': [2206], '(Roche': [2207], 'Biochemicals),': [2209], 'G418': [2215], '(400': [2216], 'μg/ml)': [2217], '4': [2219, 4290], 'weeks,': [2220], 'expanded,': [2221], 'stained': [2223, 2661], 'anti-PECAM-1,': [2225], 'μl': [2250, 2463], 'PECAM-1/GST': [2252, 2326, 2387], 'fusion': [2253, 2327, 2388, 3139, 3192, 3385, 3435], 'protein,': [2254], 'comprised': [2255], 'full': [2258], 'fused': [2262], 'GST': [2264, 3407], '1.5': [2294], 'units': [2295], 'Src': [2297, 2939, 2983, 3146], '(Upstate': [2299, 2351], '(20': [2305], 'mmHepes,': [2306], 'MgCl2,': [2311], 'mmMnCl2,': [2313], 'glycerol,': [2315], '30': [2317, 2324, 2447], 'μm': [2318], 'ATP)': [2319], '°C.': [2325], 'similarly': [2330, 2796], 'phosphorylated': [2331, 2761, 3142, 3188, 3327, 3431, 3990, 3995], 'unit': [2335], 'nPKCε': [2337], '(Life': [2339], 'Technologies,': [2340], 'kit': [2346], 'One-tenth': [2355], 'reaction': [2358, 2380], 'anti-phosphotyrosine': [2364], 'autoradiography': [2368], '(when': [2369], '[32P]ATP;': [2371], 'Amersham': [2372], 'Pharmacia': [2373], 'Biotech),': [2374], 'rest': [2377], 'products': [2381], 'pull-down': [2385, 3694], 'experiments.': [2386], 'coupled': [2390], 'glutathione-agarose': [2392], 'beads': [2393, 2474], '(10': [2394], 'μl)': [2395], 'binding': [2402, 2479, 2491, 3671, 3737, 3758], '0.1': [2419], 'mg/ml': [2420], 'albumin)': [2423], 'addition': [2433, 2495], 'lysate.': [2439], 'Samples': [2440], 'additional': [2446], 'min,': [2448, 2650], 'occasional': [2450], 'mixing': [2451], 'inversion,': [2453], 'centrifugation.': [2456], 'saved,': [2460], 'run': [2465], 'parallel': [2467], 'bead': [2470], 'pellets.': [2471], 'pellet': [2473, 3237], 'NaCl': [2485], '(final': [2486], 'concentration)': [2487], 'sample': [2497], 'buffer,': [2498], 'electrophoresis.': [2503], 'fixed': [2508, 2644], '4%': [2510, 2646], 'paraformaldehyde': [2511, 2647], 'overnight,': [2515], 'dehydrated': [2516], 'series': [2519], '50–100%': [2521], 'ethanol,': [2522], 'xylene,': [2525], 'embedded': [2527], 'paraffin.': [2529], '5-μm': [2530, 2546], 'sections': [2531, 2547, 2570], 'cut,': [2533], 'mounted': [2534], 'onto': [2535], 'slides,': [2536], 'deparaffinized,': [2537], 'rehydrated,': [2538], 'stained.': [2540], 'Immunohistochemical': [2541], 'analysis': [2542, 3572, 3945, 4022], 'standard': [2545], 'done': [2549], 'antigen': [2574], 'retrieval,': [2575], 'blocked': [2576], 'donkey': [2580, 2613, 2618], 'double-stained': [2583], 'overnight': [2584], 'goat': [2587], 'anti-human': [2588], '(C-20,': [2590], 'vimentin.': [2599], 'Sections': [2600], 'extensively': [2603], 'TBS-Triton': [2606], 'X-100': [2607], '(0.01%)': [2608], 'secondary,': [2612], 'anti-goat': [2614], 'fluorescein': [2615], 'isothiocyanate,': [2616], 'anti-mouse': [2619], 'CY3-conjugated': [2620], '(Jackson': [2622], 'ImmunoResearch,': [2623], 'West': [2624], 'Grove,': [2625], 'PA)': [2626], 'washed,': [2630], 'coverslipped.': [2632], 'Cultures': [2633], 'glass': [2641], 'coverslips,': [2642], 'permeabilized': [2651], 'immunofluorescence': [2660], 'staining,': [2684], 'coverslip': [2690], 'middle': [2697, 3686], 'cross-like': [2700], 'pattern.': [2701], 'staining.': [2711], 'All': [2712], 'experiments': [2713, 3180, 3279, 3427, 3705], 'repeated': [2715], 'similar': [2720, 3969, 4311], 'results.': [2721], 'sequence': [2726], 'examined': [2728], 'consensus': [2730], 'substrate': [2732, 2934], 'ScanProsite-Protein': [2736], 'against': [2737], 'PROSITE': [2738], 'program': [2739], '(ISREC': [2740], 'bioinformatics': [2741], 'server,': [2742], 'Lausanne,': [2743], 'SW).': [2744], 'had': [2746, 3205, 3709], 'reservoir': [2754], 'Given': [2780, 3798], 'structural': [2782, 3117], 'functional': [2784], 'similarities': [2785], '(plakoglobin),': [2790], 'asked': [2792], 'whether': [2793], 'would': [2795, 2896], 'investigated': [2801], 'potential': [2802, 2961, 3126, 4186], 'mechanisms': [2803], 'might': [2805], 'regulation': [2810], 'such': [2812], 'interaction.': [2814, 3228], 'Previously,': [2815], 'correlate': [2821], 'phosphorylation.': [2825], 'As': [2826, 3194, 3975], 'illustrated': [2827], 'Fig.1,': [2829], 'higher': [2835, 3711], 'EOMA': [2837, 3603], 'compared': [2839, 4120], 'HUVEC,': [2841], 'whereas': [2842, 3400, 3964], 'no': [2843, 3206, 3401], 'detected': [2846, 3249, 3479, 3999, 4237], '(Ref.': [2851, 3148], '2.Ilan': [2852], 'Scholar': [2868, 3172], 'Fig.': [2870, 3174, 3197, 3452, 3528], 'A).': [2872, 2894, 3281], 'culture': [2878, 3524], 'model': [2879, 3525, 3766], 'system,': [2880, 3517], 'showed': [2883], 'exact': [2885], 'opposite': [2886], 'phenotype,': [2887], 'highest': [2889], '(Fig.': [2892, 3036, 3046, 3063, 3100, 3215, 3396, 3473, 3484, 3563, 3573, 3661, 3683, 3702, 3722, 3959, 3970, 4006, 4223, 4241], 'partner': [2908], 'interaction': [2912, 3081, 3134, 3719, 3815, 4357], 'two': [2915], 'differentially': [2918], 'regulated.': [2919], 'It': [2920], 'Arm': [2925], '(p120,': [2927], 'γ-catenin)': [2930], 'targets': [2935], 'receptor': [2937], 'family': [2940, 2985], 'kinases': [2941], '(18.Daniel': [2942], 'Reynolds': [2944], 'A.B.': [2945], 'Bio': [2946], 'Essays.': [2947], '19:': [2949], '883-891Crossref': [2950], '(285)': [2953], 'Therefore,': [2956], 'study': [2959], 'its': [2968, 3040, 3080, 3133, 3293, 3780, 4056], 'ability': [2969, 3457, 3781, 3805, 4057, 4327], 'treated': [2976, 3034], 'inhibitor': [2981, 3614], 'members': [2986], '(19.Hanke': [2987], 'J.H.': [2988], 'Gardner': [2989], 'J.P.': [2990], 'Dow': [2991], 'R.L.': [2992], 'Changelian': [2993], 'P.S.': [2994], 'Brissette': [2995], 'W.H.': [2996], 'Weringer': [2997], 'E.J': [2998], 'Pollok': [2999], 'Connelly': [3001], '271:': [3007, 4179], '695-701Abstract': [3008], '(1784)': [3016], 'Immunoprecipitation': [3019], '(IP)': [3020], 'studies': [3021, 4323], 'revealed': [3022, 3951], 'although': [3024, 3230, 3728], 'levels': [3028, 3088, 3532, 3833, 3967, 3997, 4255], 'significantly': [3030, 3559], 'PP1-': [3033], 'B,top': [3038], 'panel),': [3039, 3067, 3104, 3201, 3257, 3399, 3488, 3725, 3963, 4010, 4244, 4305], 'remain': [3044], 'unchanged': [3045, 3721], 'B,': [3048, 3065, 3102], 'third': [3049, 3177, 3962], 'panel).': [3050, 3178, 3466, 3665, 3687, 3909, 3974, 4227], 'contrast,': [3052, 3600, 3716, 4229], 'completely': [3058], 'abolished': [3059], 'PP1': [3061], 'treatment': [3062, 4287], 'fourth': [3066, 3973], 'factor': [3078], 'low': [3085, 3542], 'detectable': [3087], 'co-IP': [3092, 4025], 'independently': [3095], 'phosphotyrosine': [3098], 'state,': [3099], 'fifth': [3103, 4009], 'complex': [3113], 'other': [3116], 'families': [3119], '(see': [3120], 'below).': [3121], 'To': [3122, 3412, 3501, 4183], 'analyze': [3124], 'γ-catenin,': [3136, 3810], 'GST-PECAM-1': [3138, 3191, 3384, 3434], 'ex': [3143, 3800, 4046, 4316], '11.Lu': [3149], 'C,': [3176, 3255, 4225, 4303], 'Pull-down': [3179, 3426], 'lysates': [3183, 3440, 3881], 'nonphosphorylated': [3190, 3433], 'protein.': [3193], '(top': [3200], 'effect': [3207, 4188], 'recruitment,': [3210], 'neither': [3213], 'B)': [3217, 3454], '(Fig.1': [3220, 3254, 3280], 'C)': [3221], 'necessary': [3225], 'their': [3227], 'mainly': [3233, 3248, 3328], 'fraction,': [3238], 'unable': [3241], 'interact': [3243], 'fraction': [3253], 'second': [3256, 3487], 'under': [3260], 'these': [3261, 3546, 4030], 'conditions': [3262], 'partner,': [3271], 'agreement': [3274, 3468, 4246], 'our': [3276, 3383, 3413, 3470, 3693, 3763, 4315], 'previous': [3277, 3471], 'IP': [3278, 3701, 3888, 4202], 'Although': [3282], 'much': [3283], 'recent': [3286], 'interest': [3287], 'function': [3290, 3369], 'arose': [3291], 'initially': [3323], 'characterized': [3324, 3836], 'serine': [3330], '(20.Newman': [3332], 'Hillery': [3334], 'C.A.': [3335], 'Albrecht': [3336], 'Parise': [3338], 'L.V.': [3339], 'Berndt': [3340], 'M.C.': [3341], 'Mazurov': [3342], 'A.V.': [3343], 'Dunlop': [3344], 'L.C.': [3345], 'Zhang': [3346], 'Rittehouse': [3348], 'S.E.': [3349], '119:': [3354], '239-246Crossref': [3355], '(124)': [3358], 'However,': [3361, 3910], 'level': [3375], 'yet': [3378], 'reported.': [3380], 'Incubation': [3381], 'significant': [3393, 3443, 4231], 'A,bottom': [3398], '32P': [3402], 'incorporation': [3403], 'observed': [3405, 4014], 'alone': [3408], '(data': [3409], 'shown).': [3411, 4313], 'knowledge,': [3414], 'this': [3415], 'first': [3418], 'can': [3422], 'phosphorylate': [3424], 'indicated': [3441], '(more': [3445], '6-fold': [3447], 'based': [3448, 3569], 'densitometric': [3450, 3571], 'analysis,': [3451], 'bind': [3461, 3809, 4059], '(Fig.2': [3463, 3586], 'A,': [3464, 3486, 3907, 3961, 3972, 4008], 'top': [3465, 3664, 3908, 4226], 'finding': [3472], 'C),': [3475, 3565, 3587], 'exclusively': [3492], 'modulates': [3493], 'evaluate': [3503, 4184], 'PECAM-1/β-/γ-catenin': [3509], 'context': [3513], 'took': [3519], 'advantage': [3520], 'presented': [3526], 'High': [3531], 'activity': [3544, 3594], 'cells.': [3547], 'Indeed,': [3548], 'exposure': [3549, 3601, 4240], 'physiologic': [3554], 'inducer,': [3556], 'analog,': [3558], 'decreased': [3560], '3-fold': [3568], 'D).': [3575], 'Staurosporine,': [3576], 'potent': [3578, 3610], 'inhibitor,': [3580], 'did': [3581], 'affect': [3583], 'low.': [3598], 'GF-109203x': [3607], '(bis),': [3608], '(21.Toullec': [3615], 'Pianetti': [3617], 'Cosre': [3619], 'Bellevergue': [3621], 'Grand-Perret': [3623], 'Ajakane': [3625], 'Baudet': [3627], 'Boissin': [3629], 'Boursier': [3631], 'Loriolle': [3633], 'Duhamel': [3635], 'L.': [3636], 'Charon': [3637], 'Kirilovsky': [3639], '1991;': [3644], '266:': [3645], '15771-15781Abstract': [3646], 'substantial': [3656], 'increase': [3657, 3668, 3912, 3930, 4232, 4250, 4292], 'E,': [3663, 3685], 'accompanied': [3673], 'comparable': [3676], 'lends': [3689], '(Figs.': [3695], 'and2': [3698], 'A)': [3699, 3704], 'affinity': [3712], 'PECAM-1/SHP-2': [3718, 4234], 'remained': [3720], 'E,third': [3724], 'compete': [3733], 'common': [3736], 'site/domain,': [3738], 'SHP-2-binding': [3740], 'site': [3741], 'different': [3743], '(tyrosine': [3744], '663/686': [3746], 'domain)': [3750], 'influenced': [3754], 'Taken': [3761], 'together,': [3762], 'systems': [3767], 'inverse': [3773, 4049], 'correlation': [3774, 4050], 'indicate': [3789], 'substrate.': [3797], 'sought': [3812], 'analogous': [3814], 'vivo.': [3817], 'Significant': [3818], 'increases': [3819], 'extraembryonic': [3821], 'embryonic': [3823, 3941, 4071], 'vasculogenesis,': [3824], 'concomitant': [3827], 'developing': [3845], 'conceptus': [3847, 3871], 'Lysates,': [3866], 'whole': [3870], '8.5': [3876, 4004], 'sac': [3880, 3933, 4069, 4199], 'immunoblotting.': [3894], 'γ-Catenin': [3895], 'all': [3904, 4324], 'stages': [3905, 4031], '(Fig.3': [3906, 4209, 4302], 'occurred': [3916], 'p.c.,': [3922], 'stage': [3924], 'there': [3927], 'island': [3935], 'formation': [3936, 3939], 'simultaneous': [3938], 'vasculature.': [3942], 'immunoblot': [3944], 'lysate': [3949], 'marked': [3953], 'reactivity': [3958, 4018, 4028], '3': [3960, 3971, 4007, 4224, 4242], 'control,': [3977, 4192], 'striped': [3982], 'reprobed': [3984], 'MAPK.': [3991], 'No': [3992], 'changes': [3993], 'P-PKC': [4017, 4027], 'specific.': [4020], 'Densitometric': [4021], 'development': [4035], 'summarized': [4037], 'Fig.3': [4039], 'observations': [4042], 'vivo/in': [4047], 'γ-catenin.': [4060], 'hyperglycemia': [4066], 'causes': [4067], 'vasculopathy': [4072], 'hyper-phosphorylated': [4109], 'hyperglycemic': [4114], 'control': [4122], 'reports': [4151], 'documented': [4153], 'glucose-induced': [4155, 4249], 'activity,': [4157], '(24.Rattan': [4165], 'Shen': [4167], 'Sultana': [4169], 'C.': [4170], 'Kumar': [4171], 'Kalra': [4173], 'E711-E717PubMed': [4180], 'interactions,': [4191], 'glucose-treated': [4194, 4221], 'C).': [4210], 'two-fold': [4212], 'C,middle': [4243], 'induced': [4288], 'fold': [4291], 'phosphorylation,': [4295, 4340], 'judged': [4297], 'anti-phospho': [4299], 'bottom': [4304], 'while': [4306], 'profile': [4309], '(not': [4312], 'Thus,': [4314], 'vivo,': [4317], 'vitro,': [4319], 'point': [4336], 'mediated,': [4341], 'part,': [4345], 'mechanism.': [4352], 'Having': [4353], 'biochemically,': [4358], 'interested': [4361], 'possible': [4364], 'funct': [4365]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1978577250', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-10T03:03:41.730878', 'created_date': '2016-06-24'}