Publication Information

{'id': 'https://openalex.org/W1978505405', 'doi': 'https://doi.org/10.1083/jcb.103.3.917', 'title': 'Microtubule reassembly from nucleating fragments during the regrowth of amputated neurites.', 'display_name': 'Microtubule reassembly from nucleating fragments during the regrowth of amputated neurites.', 'publication_year': 1986, 'publication_date': '1986-09-01', 'ids': {'openalex': 'https://openalex.org/W1978505405', 'doi': 'https://doi.org/10.1083/jcb.103.3.917', 'mag': '1978505405', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3745275', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2114289'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.103.3.917', 'pdf_url': 'http://jcb.rupress.org/content/jcb/103/3/917.full.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://jcb.rupress.org/content/jcb/103/3/917.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5072020119', 'display_name': 'Peter W. Baas', 'orcid': 'https://orcid.org/0000-0002-1272-4538'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'P W Baas', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109051972', 'display_name': 'S R Heidemann', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'S R Heidemann', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.44, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 91, 'citation_normalized_percentile': {'value': 0.955611, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '103', 'issue': '3', 'first_page': '917', 'last_page': '927'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13526', 'display_name': '14-3-3 protein interactions', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11752', 'display_name': 'Cancer Treatment and Pharmacology', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nocodazole', 'display_name': 'Nocodazole', 'score': 0.9342787}, {'id': 'https://openalex.org/keywords/neurite', 'display_name': 'Neurite', 'score': 0.8828534}, {'id': 'https://openalex.org/keywords/electron-micrographs', 'display_name': 'Electron micrographs', 'score': 0.42587942}], 'concepts': [{'id': 'https://openalex.org/C2779363559', 'wikidata': 'https://www.wikidata.org/wiki/Q2506092', 'display_name': 'Nocodazole', 'level': 4, 'score': 0.9342787}, {'id': 'https://openalex.org/C113246987', 'wikidata': 'https://www.wikidata.org/wiki/Q1534415', 'display_name': 'Neurite', 'level': 3, 'score': 0.8828534}, {'id': 'https://openalex.org/C20418707', 'wikidata': 'https://www.wikidata.org/wiki/Q189933', 'display_name': 'Microtubule', 'level': 2, 'score': 0.738116}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6701687}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5873522}, {'id': 'https://openalex.org/C2779530196', 'wikidata': 'https://www.wikidata.org/wiki/Q178999', 'display_name': 'Axon', 'level': 2, 'score': 0.47834727}, {'id': 'https://openalex.org/C3018767501', 'wikidata': 'https://www.wikidata.org/wiki/Q130416', 'display_name': 'Electron micrographs', 'level': 3, 'score': 0.42587942}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.36728668}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3664115}, {'id': 'https://openalex.org/C93877712', 'wikidata': 'https://www.wikidata.org/wiki/Q132560', 'display_name': 'Electron microscope', 'level': 2, 'score': 0.25716996}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.22372437}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.21403277}, {'id': 'https://openalex.org/C142669718', 'wikidata': 'https://www.wikidata.org/wiki/Q154626', 'display_name': 'Cytoskeleton', 'level': 3, 'score': 0.19500044}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009416', 'descriptor_name': 'Nerve Regeneration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001562', 'descriptor_name': 'Benzimidazoles', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D001562', 'descriptor_name': 'Benzimidazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002642', 'descriptor_name': 'Chick Embryo', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015739', 'descriptor_name': 'Nocodazole', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.103.3.917', 'pdf_url': 'http://jcb.rupress.org/content/jcb/103/3/917.full.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2114289', 'pdf_url': 'https://europepmc.org/articles/pmc2114289?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114289', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3745275', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.103.3.917', 'pdf_url': 'http://jcb.rupress.org/content/jcb/103/3/917.full.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W1560838466', 'https://openalex.org/W1769356601', 'https://openalex.org/W1965404941', 'https://openalex.org/W1971407845', 'https://openalex.org/W1977595726', 'https://openalex.org/W1977798242', 'https://openalex.org/W1996940538', 'https://openalex.org/W1999020300', 'https://openalex.org/W2005500113', 'https://openalex.org/W2007785335', 'https://openalex.org/W2007828663', 'https://openalex.org/W2011521398', 'https://openalex.org/W2016529329', 'https://openalex.org/W2023025082', 'https://openalex.org/W2023151430', 'https://openalex.org/W2039303292', 'https://openalex.org/W2041508271', 'https://openalex.org/W2044675881', 'https://openalex.org/W2048408287', 'https://openalex.org/W2053528452', 'https://openalex.org/W2065620363', 'https://openalex.org/W2067299834', 'https://openalex.org/W2079310684', 'https://openalex.org/W2083549663', 'https://openalex.org/W2083596288', 'https://openalex.org/W2085401477', 'https://openalex.org/W2086994573', 'https://openalex.org/W2093015260', 'https://openalex.org/W2100181443', 'https://openalex.org/W2110067044', 'https://openalex.org/W2122106829', 'https://openalex.org/W2136333299', 'https://openalex.org/W2138948965', 'https://openalex.org/W2140972604', 'https://openalex.org/W2147943204', 'https://openalex.org/W2152055092', 'https://openalex.org/W2158858402', 'https://openalex.org/W2167836653', 'https://openalex.org/W2170671667', 'https://openalex.org/W2396452', 'https://openalex.org/W2410661275', 'https://openalex.org/W2414102877', 'https://openalex.org/W2462019458'], 'related_works': ['https://openalex.org/W34790991', 'https://openalex.org/W2312992091', 'https://openalex.org/W2138300261', 'https://openalex.org/W2104055042', 'https://openalex.org/W2071528423', 'https://openalex.org/W2069851853', 'https://openalex.org/W2067495959', 'https://openalex.org/W2015893917', 'https://openalex.org/W1993379114', 'https://openalex.org/W1543755059'], 'abstract_inverted_index': {'We': [0, 96, 224, 286, 363], 'have': [1], 'proposed': [2], 'that': [3, 8, 51, 83, 204, 229, 246, 288, 311, 328, 365], 'stable': [4], 'microtubule': [5], '(MT)': [6], 'fragments': [7, 216, 232], 'resist': [9], 'depolymerization': [10, 208], 'may': [11], 'serve': [12], 'as': [13, 227], 'nucleating': [14], 'elements': [15], 'for': [16, 112, 119, 260], 'the': [17, 24, 58, 63, 68, 137, 147, 190, 193, 230, 240, 243, 306, 312, 366], 'local': [18], 'control': [19], 'of': [20, 60, 65, 71, 81, 151, 157, 162, 174, 186, 198, 242, 256, 266, 305, 314, 325, 370, 375], 'MT': [21, 104, 207, 215, 231, 244, 378, 383], 'dynamics': [22], 'in': [23, 55, 62, 209, 220, 233, 276, 282, 293, 327], 'axon': [25], '(Heidemann,': [26], 'S.': [27, 32, 37], 'R.,': [28], 'M.': [29], 'A.': [30], 'Hamborg,': [31], 'J.': [33, 43], 'Thomas,': [34], 'B.': [35], 'Song,': [36], 'Lindley,': [38], 'and': [39, 88, 101, 164, 268, 356], 'D.': [40, 89], 'Chu,': [41], '1984,': [42], 'Cell': [44, 93], 'Biol.,': [45], '99:1289-1295).': [46], 'Here': [47], 'we': [48], 'report': [49], 'evidence': [50, 228], 'supports': [52], 'this': [53, 226], 'proposal': [54], 'studies': [56], 'on': [57], 'role': [59], 'MTs': [61, 156, 182, 188, 267, 289, 319, 355], 'regrowth': [64, 100, 102, 126, 173, 369], 'neurites': [66, 77, 175, 212, 250, 358, 371], 'from': [67, 176, 189, 239, 340, 372], 'distal': [69], 'segments': [70], 'amputated': [72], 'chick': [73], 'sensory': [74], 'neurites.': [75, 342], 'Amputated': [76], 'collapse': [78], 'to': [79, 139, 218, 317, 322, 353, 381], '"beads"': [80], 'axoplasm': [82, 376], 'rapidly': [84], 'regrow': [85, 357], '(Shaw,': [86], 'G.,': [87], 'Bray,': [90], '1977,': [91], 'Exp.': [92], 'Res.,': [94], '104:55-62).': [95], 'examined': [97], 'both': [98], 'unarrested': [99], 'after': [103, 271, 303], 'disassembly': [105], 'by': [106, 359], 'either': [107], 'cold': [108], '(-5': [109], 'degrees': [110, 142], 'C': [111, 143], '2': [113], 'h)': [114], 'or': [115, 144], 'nocodazole': [116, 257, 299, 326, 348], '(0.1': [117], 'microgram/ml': [118, 259, 298, 347], '15-20': [120, 261, 273], 'min).': [121], 'In': [122], 'all': [123], 'these': [124, 315], 'cases': [125, 278], 'occurred': [127], 'at': [128], '3.5-4.5': [129], 'micron/min': [130], 'with': [131, 252, 296, 345, 361], 'no': [132], 'delay': [133, 275], 'times': [134, 138], 'other': [135, 284], 'than': [136], 'reach': [140], '37': [141], 'rinse': [145], 'out': [146], 'nocodazole.': [148], 'Electron': [149, 196], 'micrographs': [150, 197], 'untreated': [152, 210], 'beads': [153, 166, 177, 200, 235, 294, 316, 374], 'show': [154, 167, 213], 'many': [155], 'varying': [158], 'lengths,': [159], 'while': [160], 'those': [161, 219], 'cold-': [163], 'nocodazole-treated': [165], 'markedly': [168], 'shorter': [169], 'MTs.': [170], 'The': [171], 'robust': [172, 368], 'containing': [178], 'only': [179, 270], 'very': [180], 'short': [181], 'argues': [183], 'against': [184], 'unfurling': [185], 'intact': [187, 211, 341], 'bead': [191], 'into': [192], 'growing': [194], 'neurite.': [195], 'cold-treated': [199, 222, 234], 'lysed': [201], 'under': [202], 'conditions': [203], 'cause': [205], 'substantial': [206], 'persistent': [214], 'similar': [217], 'unlysed': [221], 'beads.': [223], 'interpret': [225], 'are': [236], 'somehow': [237], 'distinct': [238], 'majority': [241], 'mass': [245], 'had': [247], 'depolymerized.': [248], 'Collapsed': [249], 'treated': [251, 295, 344], 'a': [253, 272, 329], 'higher': [254, 331], 'dose': [255, 332], '(1.0': [258], 'min)': [262], 'were': [263], 'completely': [264], 'devoid': [265], 'regrew': [269, 281], 'min': [274, 302], 'two': [277], 'but': [279], 'never': [280], '11': [283], 'cases.': [285], 'found': [287], 'did': [290], 'not': [291], 'return': [292], '1.0': [297, 346], 'even': [300], '30': [301], 'removal': [304, 324], 'drug.': [307], 'It': [308], 'was': [309, 320], 'unlikely': [310], 'inability': [313], 'reassemble': [318, 354], 'due': [321], 'incomplete': [323], 'much': [330], '(20': [333], 'micrograms/ml': [334], 'nocodazole)': [335], 'could': [336], 'be': [337, 351], 'quickly': [338], 'rinsed': [339], 'Beads': [343], 'could,': [349], 'however,': [350], 'stimulated': [352], 'treatment': [360], 'taxol.': [362], 'conclude': [364], 'immediate,': [367], 'collapsed': [373], 'requires': [377], 'nucleation': [379], 'sites': [380], 'support': [382], 'reassembly.(ABSTRACT': [384], 'TRUNCATED': [385], 'AT': [386], '400': [387], 'WORDS)': [388]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1978505405', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-14T07:16:13.866105', 'created_date': '2016-06-24'}