Title: Antibacterial activity and mode of action of plant flavonoids against Proteus vulgaris and Staphylococcus aureus
Abstract: (−)-Epigallocatechin, an antibiotic found in Elaeagnus glabra, and 28 other related plant flavonoids were tested for their antibacterial activity against Proteus vulgaris and Staphylococcus aureus. A free 3′,4′,5′-trihydroxy B-ring and a free 3-OH were necessary for antibacterial activity. DNA synthesis was predominantly inhibited by the active flavonoids in P. vulgaris, whereas RNA synthesis was inhibited in S. aureus.
Publication Year: 1987
Publication Date: 1987-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 276
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