Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1977666051', 'doi': 'https://doi.org/10.1021/jm990554g', 'title': 'The PPARs: From Orphan Receptors to Drug Discovery', 'display_name': 'The PPARs: From Orphan Receptors to Drug Discovery', 'publication_year': 2000, 'publication_date': '2000-02-01', 'ids': {'openalex': 'https://openalex.org/W1977666051', 'doi': 'https://doi.org/10.1021/jm990554g', 'mag': '1977666051', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10691680'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/jm990554g', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S162030435', 'display_name': 'Journal of Medicinal Chemistry', 'issn_l': '0022-2623', 'issn': ['0022-2623', '1520-4804'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081551458', 'display_name': 'Timothy M. Willson', 'orcid': 'https://orcid.org/0000-0003-4181-8223'}, 'institutions': [{'id': 'https://openalex.org/I1309191912', 'display_name': 'Research Triangle Park Foundation', 'ror': 'https://ror.org/03eqttr49', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1309191912']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Timothy M. Willson', 'raw_affiliation_strings': ['Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709, USA.', 'institution_ids': ['https://openalex.org/I1309191912']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084973541', 'display_name': 'Peter J. Brown', 'orcid': 'https://orcid.org/0000-0002-8454-0367'}, 'institutions': [{'id': 'https://openalex.org/I1309191912', 'display_name': 'Research Triangle Park Foundation', 'ror': 'https://ror.org/03eqttr49', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1309191912']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Peter J. Brown', 'raw_affiliation_strings': ['Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709', 'institution_ids': ['https://openalex.org/I1309191912']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087328082', 'display_name': 'Daniel D. Sternbach', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1309191912', 'display_name': 'Research Triangle Park Foundation', 'ror': 'https://ror.org/03eqttr49', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1309191912']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Daniel D. Sternbach', 'raw_affiliation_strings': ['Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709', 'institution_ids': ['https://openalex.org/I1309191912']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007243474', 'display_name': 'Brad R. Henke', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1309191912', 'display_name': 'Research Triangle Park Foundation', 'ror': 'https://ror.org/03eqttr49', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1309191912']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Brad R. Henke', 'raw_affiliation_strings': ['Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicinal Chemistry, Glaxo Wellcome Research & Development, Research Triangle Park, North Carolina 27709', 'institution_ids': ['https://openalex.org/I1309191912']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 11.48, 'has_fulltext': False, 'cited_by_count': 1779, 'citation_normalized_percentile': {'value': 0.99954, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '43', 'issue': '4', 'first_page': '527', 'last_page': '550'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11072', 'display_name': 'Peroxisome Proliferator-Activated Receptors', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11072', 'display_name': 'Peroxisome Proliferator-Activated Receptors', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11618', 'display_name': 'Cholesterol Metabolism and Atherosclerosis', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13991', 'display_name': 'Nurr1/CoREST Pathway in Neuroprotection and Inflammation', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ppars', 'display_name': 'PPARs', 'score': 0.546547}, {'id': 'https://openalex.org/keywords/nuclear-receptors', 'display_name': 'Nuclear Receptors', 'score': 0.519313}, {'id': 'https://openalex.org/keywords/icon', 'display_name': 'Icon', 'score': 0.4993596}], 'concepts': [{'id': 'https://openalex.org/C2778805511', 'wikidata': 'https://www.wikidata.org/wiki/Q1713', 'display_name': 'Citation', 'level': 2, 'score': 0.5772345}, {'id': 'https://openalex.org/C518677369', 'wikidata': 'https://www.wikidata.org/wiki/Q202833', 'display_name': 'Social media', 'level': 2, 'score': 0.5367606}, {'id': 'https://openalex.org/C161191863', 'wikidata': 'https://www.wikidata.org/wiki/Q199655', 'display_name': 'Library science', 'level': 1, 'score': 0.5077597}, {'id': 'https://openalex.org/C2778447006', 'wikidata': 'https://www.wikidata.org/wiki/Q1156474', 'display_name': 'Icon', 'level': 2, 'score': 0.4993596}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.45158985}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.33969563}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.33054}, {'id': 'https://openalex.org/C199360897', 'wikidata': 'https://www.wikidata.org/wiki/Q9143', 'display_name': 'Programming language', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015195', 'descriptor_name': 'Drug Design', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003920', 'descriptor_name': 'Diabetes Mellitus', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D003920', 'descriptor_name': 'Diabetes Mellitus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003920', 'descriptor_name': 'Diabetes Mellitus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006949', 'descriptor_name': 'Hyperlipidemias', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006949', 'descriptor_name': 'Hyperlipidemias', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006949', 'descriptor_name': 'Hyperlipidemias', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/jm990554g', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S162030435', 'display_name': 'Journal of Medicinal Chemistry', 'issn_l': '0022-2623', 'issn': ['0022-2623', '1520-4804'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10691680', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.47, 'display_name': 'Partnerships for the goals', 'id': 'https://metadata.un.org/sdg/17'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 216, 'referenced_works': ['https://openalex.org/W1505047300', 'https://openalex.org/W1527827101', 'https://openalex.org/W1544251730', 'https://openalex.org/W1548401583', 'https://openalex.org/W1551488257', 'https://openalex.org/W1567127662', 'https://openalex.org/W1583731895', 'https://openalex.org/W1608005125', 'https://openalex.org/W1626382598', 'https://openalex.org/W1633340712', 'https://openalex.org/W1639924204', 'https://openalex.org/W1641016126', 'https://openalex.org/W1671834350', 'https://openalex.org/W1672804368', 'https://openalex.org/W1673496785', 'https://openalex.org/W1843523988', 'https://openalex.org/W1926862327', 'https://openalex.org/W1958865153', 'https://openalex.org/W1965240451', 'https://openalex.org/W1966861485', 'https://openalex.org/W1967315954', 'https://openalex.org/W1968703258', 'https://openalex.org/W1969478165', 'https://openalex.org/W1970312964', 'https://openalex.org/W1971817110', 'https://openalex.org/W1972220181', 'https://openalex.org/W1975160900', 'https://openalex.org/W1975884121', 'https://openalex.org/W1975927677', 'https://openalex.org/W1976621212', 'https://openalex.org/W1978125779', 'https://openalex.org/W1979466688', 'https://openalex.org/W1979761686', 'https://openalex.org/W1979892446', 'https://openalex.org/W1980198526', 'https://openalex.org/W1981152838', 'https://openalex.org/W1982047106', 'https://openalex.org/W1984081543', 'https://openalex.org/W1985661891', 'https://openalex.org/W1985683101', 'https://openalex.org/W1985709687', 'https://openalex.org/W1985735647', 'https://openalex.org/W1986219421', 'https://openalex.org/W1987096050', 'https://openalex.org/W1989050470', 'https://openalex.org/W1989535139', 'https://openalex.org/W1990007208', 'https://openalex.org/W1991592955', 'https://openalex.org/W1992180018', 'https://openalex.org/W1992448487', 'https://openalex.org/W1992968076', 'https://openalex.org/W1993342645', 'https://openalex.org/W1993423079', 'https://openalex.org/W1994212260', 'https://openalex.org/W1995272384', 'https://openalex.org/W1996256476', 'https://openalex.org/W1996499493', 'https://openalex.org/W1996687344', 'https://openalex.org/W1998699321', 'https://openalex.org/W1998787622', 'https://openalex.org/W1999143122', 'https://openalex.org/W1999461623', 'https://openalex.org/W2002438078', 'https://openalex.org/W2002519246', 'https://openalex.org/W2002851125', 'https://openalex.org/W2003856834', 'https://openalex.org/W2003960793', 'https://openalex.org/W2005508351', 'https://openalex.org/W2005674716', 'https://openalex.org/W2008632158', 'https://openalex.org/W2008881244', 'https://openalex.org/W2010443000', 'https://openalex.org/W2011982810', 'https://openalex.org/W2012920450', 'https://openalex.org/W2013498640', 'https://openalex.org/W2017645978', 'https://openalex.org/W2018583688', 'https://openalex.org/W2019349841', 'https://openalex.org/W2019899393', 'https://openalex.org/W2021758696', 'https://openalex.org/W2021822798', 'https://openalex.org/W2022766726', 'https://openalex.org/W2023404311', 'https://openalex.org/W2023463659', 'https://openalex.org/W2024682491', 'https://openalex.org/W2027269951', 'https://openalex.org/W2027324370', 'https://openalex.org/W2028661874', 'https://openalex.org/W2029186389', 'https://openalex.org/W2030183049', 'https://openalex.org/W2031694725', 'https://openalex.org/W2032786707', 'https://openalex.org/W2034953645', 'https://openalex.org/W2035000881', 'https://openalex.org/W2035182977', 'https://openalex.org/W2036154351', 'https://openalex.org/W2037094605', 'https://openalex.org/W2040671595', 'https://openalex.org/W2041130899', 'https://openalex.org/W2041229954', 'https://openalex.org/W2041956872', 'https://openalex.org/W2043334203', 'https://openalex.org/W2044359996', 'https://openalex.org/W2044548466', 'https://openalex.org/W2045725952', 'https://openalex.org/W2045984034', 'https://openalex.org/W2046268728', 'https://openalex.org/W2047399305', 'https://openalex.org/W2047796161', 'https://openalex.org/W2047982128', 'https://openalex.org/W2050092688', 'https://openalex.org/W2050352100', 'https://openalex.org/W2050360984', 'https://openalex.org/W2050671706', 'https://openalex.org/W2050717908', 'https://openalex.org/W2050904588', 'https://openalex.org/W2050915632', 'https://openalex.org/W2051824140', 'https://openalex.org/W2054234087', 'https://openalex.org/W2054851194', 'https://openalex.org/W2055728675', 'https://openalex.org/W2058945850', 'https://openalex.org/W2058967307', 'https://openalex.org/W2060409824', 'https://openalex.org/W2060846519', 'https://openalex.org/W2061262646', 'https://openalex.org/W2062086277', 'https://openalex.org/W2062155521', 'https://openalex.org/W2063521013', 'https://openalex.org/W2063573267', 'https://openalex.org/W2064974844', 'https://openalex.org/W2065107673', 'https://openalex.org/W2065876677', 'https://openalex.org/W2066092624', 'https://openalex.org/W2066721136', 'https://openalex.org/W2068067085', 'https://openalex.org/W2068669347', 'https://openalex.org/W2070383730', 'https://openalex.org/W2075631818', 'https://openalex.org/W2076452736', 'https://openalex.org/W2077000982', 'https://openalex.org/W2078535741', 'https://openalex.org/W2081846665', 'https://openalex.org/W2081961922', 'https://openalex.org/W2082049752', 'https://openalex.org/W2083811960', 'https://openalex.org/W2084462922', 'https://openalex.org/W2084722787', 'https://openalex.org/W2086043350', 'https://openalex.org/W2086376157', 'https://openalex.org/W2087587019', 'https://openalex.org/W2087647782', 'https://openalex.org/W2090381368', 'https://openalex.org/W2090553336', 'https://openalex.org/W2090635919', 'https://openalex.org/W2091321756', 'https://openalex.org/W2091673549', 'https://openalex.org/W2091824172', 'https://openalex.org/W2092823267', 'https://openalex.org/W2094910936', 'https://openalex.org/W2095386411', 'https://openalex.org/W2100820757', 'https://openalex.org/W2102005461', 'https://openalex.org/W2103100606', 'https://openalex.org/W2103633745', 'https://openalex.org/W2106038332', 'https://openalex.org/W2107752044', 'https://openalex.org/W2113456624', 'https://openalex.org/W2113868760', 'https://openalex.org/W2116470680', 'https://openalex.org/W2120116378', 'https://openalex.org/W2120432009', 'https://openalex.org/W2124839644', 'https://openalex.org/W2125090169', 'https://openalex.org/W2125344994', 'https://openalex.org/W2127550817', 'https://openalex.org/W2129923494', 'https://openalex.org/W2131037449', 'https://openalex.org/W2131538153', 'https://openalex.org/W2134066661', 'https://openalex.org/W2135173562', 'https://openalex.org/W2138289723', 'https://openalex.org/W2139002144', 'https://openalex.org/W2139717510', 'https://openalex.org/W2140161647', 'https://openalex.org/W2140254580', 'https://openalex.org/W2140787817', 'https://openalex.org/W2147627625', 'https://openalex.org/W2147760530', 'https://openalex.org/W2150500559', 'https://openalex.org/W2150845777', 'https://openalex.org/W2151807579', 'https://openalex.org/W2152039811', 'https://openalex.org/W2152675122', 'https://openalex.org/W2152719349', 'https://openalex.org/W2156124022', 'https://openalex.org/W2161816485', 'https://openalex.org/W2162351720', 'https://openalex.org/W2164015929', 'https://openalex.org/W2165011536', 'https://openalex.org/W2169224393', 'https://openalex.org/W2170117186', 'https://openalex.org/W2170831952', 'https://openalex.org/W2171716790', 'https://openalex.org/W2184834626', 'https://openalex.org/W2321375101', 'https://openalex.org/W2326709195', 'https://openalex.org/W2328529137', 'https://openalex.org/W2333284976', 'https://openalex.org/W2335526677', 'https://openalex.org/W2425383663', 'https://openalex.org/W260520895', 'https://openalex.org/W3063220799', 'https://openalex.org/W4243394305', 'https://openalex.org/W4248595930', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4360922125', 'https://openalex.org/W4207071872', 'https://openalex.org/W3175319091', 'https://openalex.org/W2981902742', 'https://openalex.org/W2748952813', 'https://openalex.org/W220677501', 'https://openalex.org/W2175435306', 'https://openalex.org/W2076882245', 'https://openalex.org/W2056060060', 'https://openalex.org/W1504514227'], 'abstract_inverted_index': {'ADVERTISEMENT': [0], 'RETURN': [1], 'TO': [2], 'ISSUEPerspectiveNEXTThe': [3], 'PPARs:': [4], 'From': [5], 'Orphan': [6], 'Receptors': [7], 'to': [8, 103, 108], 'Drug': [9], 'Discovery†Timothy': [10], 'M.': [11], 'Willson,': [12], 'Peter': [13], 'J.': [14, 42], 'Brown,': [15], 'Daniel': [16], 'D.': [17], 'Sternbach,': [18], 'and': [19, 91, 96, 125, 169, 186, 202, 204], 'Brad': [20], 'R.': [21], 'HenkeView': [22], 'Author': [23], 'Information': [24], 'Department': [25], 'of': [26, 81, 116, 142], 'Medicinal': [27], 'Chemistry,': [28], 'Glaxo': [29], 'Wellcome': [30], 'Research': [31, 34], '&': [32], 'Development,': [33], 'Triangle': [35], 'Park,': [36], 'North': [37], 'Carolina': [38], '27709': [39], 'Cite': [40], 'this:': [41], 'Med.': [43], 'Chem.': [44], '2000,': [45], '43,': [46], '4,': [47], '527–550Publication': [48], 'Date': [49], '(Web):February': [50], '24,': [51], '2000Publication': [52], 'History': [53], 'Received8': [54], 'November': [55, 87], '1999Published': [56], 'online24': [57], 'February': [58, 62], '2000Published': [59], 'inissue': [60], '1': [61], '2000https://pubs.acs.org/doi/10.1021/jm990554ghttps://doi.org/10.1021/jm990554greview-articleACS': [63], 'PublicationsCopyright': [64], '©': [65], '2000': [66], 'American': [67], 'Chemical': [68], 'SocietyRequest': [69], 'reuse': [70], 'permissionsArticle': [71], 'Views6740Altmetric-Citations1452LEARN': [72], 'ABOUT': [73], 'THESE': [74], 'METRICSArticle': [75], 'Views': [76], 'are': [77, 100, 113], 'the': [78, 109, 114, 143, 154, 167, 170, 175, 182, 188], 'COUNTER-compliant': [79], 'sum': [80], 'full': [82], 'text': [83], 'article': [84, 148], 'downloads': [85], 'since': [86], '2008': [88], '(both': [89], 'PDF': [90], 'HTML)': [92], 'across': [93], 'all': [94], 'institutions': [95], 'individuals.': [97], 'These': [98], 'metrics': [99], 'regularly': [101], 'updated': [102, 126], 'reflect': [104], 'usage': [105], 'leading': [106], 'up': [107], 'last': [110], 'few': [111], 'days.Citations': [112], 'number': [115], 'other': [117], 'articles': [118], 'citing': [119], 'this': [120], 'article,': [121], 'calculated': [122], 'by': [123], 'Crossref': [124, 132], 'daily.': [127], 'Find': [128, 178], 'more': [129, 179], 'information': [130, 180], 'about': [131, 166], 'citation': [133], 'counts.The': [134], 'Altmetric': [135, 183], 'Attention': [136, 184], 'Score': [137, 185], 'is': [138, 190], 'a': [139, 146, 159], 'quantitative': [140], 'measure': [141], 'attention': [144], 'that': [145], 'research': [147], 'has': [149], 'received': [150], 'online.': [151], 'Clicking': [152], 'on': [153, 181], 'donut': [155], 'icon': [156], 'will': [157], 'load': [158], 'page': [160], 'at': [161], 'altmetric.com': [162], 'with': [163, 198], 'additional': [164], 'details': [165], 'score': [168, 189], 'social': [171], 'media': [172], 'presence': [173], 'for': [174], 'given': [176], 'article.': [177], 'how': [187], 'calculated.': [191], 'Share': [192, 207], 'Add': [193], 'toView': [194], 'InAdd': [195], 'Full': [196], 'Text': [197], 'ReferenceAdd': [199], 'Description': [200], 'ExportRISCitationCitation': [201], 'abstractCitation': [203], 'referencesMore': [205], 'Options': [206], 'onFacebookTwitterWechatLinked': [208], 'InRedditEmail': [209], 'Other': [210], 'access': [211], 'optionsGet': [212], 'e-Alertsclose': [213], 'SUBJECTS:Agonists,Ligands,Lipids,Receptors,Rodent': [214], 'models': [215], 'Get': [216], 'e-Alerts': [217]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1977666051', 'counts_by_year': [{'year': 2024, 'cited_by_count': 21}, {'year': 2023, 'cited_by_count': 34}, {'year': 2022, 'cited_by_count': 35}, {'year': 2021, 'cited_by_count': 43}, {'year': 2020, 'cited_by_count': 40}, {'year': 2019, 'cited_by_count': 39}, {'year': 2018, 'cited_by_count': 45}, {'year': 2017, 'cited_by_count': 40}, {'year': 2016, 'cited_by_count': 48}, {'year': 2015, 'cited_by_count': 59}, {'year': 2014, 'cited_by_count': 55}, {'year': 2013, 'cited_by_count': 57}, {'year': 2012, 'cited_by_count': 90}], 'updated_date': '2024-09-12T20:45:32.620659', 'created_date': '2016-06-24'}