Publication Information

{'id': 'https://openalex.org/W1977469218', 'doi': 'https://doi.org/10.1158/1538-7445.am2013-2545', 'title': 'Abstract 2545: Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in Chinese.', 'display_name': 'Abstract 2545: Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in Chinese.', 'publication_year': 2013, 'publication_date': '2013-04-01', 'ids': {'openalex': 'https://openalex.org/W1977469218', 'doi': 'https://doi.org/10.1158/1538-7445.am2013-2545', 'mag': '1977469218'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2013-2545', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001453048', 'display_name': 'Hongbing Shen', 'orcid': 'https://orcid.org/0000-0002-2581-5906'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongbing Shen', 'raw_affiliation_strings': ['1Nanjing Medical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': '1Nanjing Medical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101700477', 'display_name': 'Jing Dong', 'orcid': 'https://orcid.org/0000-0001-9856-5963'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jing Dong', 'raw_affiliation_strings': ['1Nanjing Medical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': '1Nanjing Medical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032100785', 'display_name': 'Guangfu Jin', 'orcid': 'https://orcid.org/0000-0003-0249-5337'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guangfu Jin', 'raw_affiliation_strings': ['1Nanjing Medical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': '1Nanjing Medical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077469902', 'display_name': 'Minjie Chu', 'orcid': 'https://orcid.org/0000-0002-7533-9119'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Minjie Chu', 'raw_affiliation_strings': ['1Nanjing Medical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': '1Nanjing Medical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100674237', 'display_name': 'Dongxin Lin', 'orcid': 'https://orcid.org/0000-0002-8723-8868'}, 'institutions': [{'id': 'https://openalex.org/I2801228662', 'display_name': 'Peking Union Medical College Hospital', 'ror': 'https://ror.org/04jztag35', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801228662']}, {'id': 'https://openalex.org/I200296433', 'display_name': 'Chinese Academy of Medical Sciences & Peking Union Medical College', 'ror': 'https://ror.org/02drdmm93', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I200296433']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Dongxin Lin', 'raw_affiliation_strings': ['2Chinese Academy of Medical Sciences and Peking Union Medical College, China.'], 'affiliations': [{'raw_affiliation_string': '2Chinese Academy of Medical Sciences and Peking Union Medical College, China.', 'institution_ids': ['https://openalex.org/I2801228662', 'https://openalex.org/I200296433']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5031063948', 'display_name': 'Zhinbin Hu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhinbin Hu', 'raw_affiliation_strings': ['1Nanjing Medical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': '1Nanjing Medical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I83519826']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 65}, 'biblio': {'volume': '73', 'issue': '8_Supplement', 'first_page': '2545', 'last_page': '2545'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11970', 'display_name': 'Molecular Biology Techniques and Applications', 'score': 0.9738, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/genome-wide-association-study', 'display_name': 'Genome-wide Association Study', 'score': 0.71944445}, {'id': 'https://openalex.org/keywords/lung-cancer-susceptibility', 'display_name': 'Lung cancer susceptibility', 'score': 0.42751274}, {'id': 'https://openalex.org/keywords/linkage-disequilibrium', 'display_name': 'Linkage Disequilibrium', 'score': 0.42674264}, {'id': 'https://openalex.org/keywords/genetic-predisposition', 'display_name': 'Genetic predisposition', 'score': 0.41276315}], 'concepts': [{'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.76428425}, {'id': 'https://openalex.org/C106208931', 'wikidata': 'https://www.wikidata.org/wiki/Q1098876', 'display_name': 'Genome-wide association study', 'level': 5, 'score': 0.71944445}, {'id': 'https://openalex.org/C156957248', 'wikidata': 'https://www.wikidata.org/wiki/Q1862216', 'display_name': 'Odds ratio', 'level': 2, 'score': 0.67597103}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.5159798}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5057523}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.50051427}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.47060332}, {'id': 'https://openalex.org/C2781182431', 'wikidata': 'https://www.wikidata.org/wiki/Q356033', 'display_name': 'Adenocarcinoma', 'level': 3, 'score': 0.46168202}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.43866545}, {'id': 'https://openalex.org/C2779372377', 'wikidata': 'https://www.wikidata.org/wiki/Q17147792', 'display_name': 'Lung cancer susceptibility', 'level': 5, 'score': 0.42751274}, {'id': 'https://openalex.org/C35605836', 'wikidata': 'https://www.wikidata.org/wiki/Q2064311', 'display_name': 'Linkage disequilibrium', 'level': 5, 'score': 0.42674264}, {'id': 'https://openalex.org/C44249647', 'wikidata': 'https://www.wikidata.org/wiki/Q208498', 'display_name': 'Confidence interval', 'level': 2, 'score': 0.4144771}, {'id': 'https://openalex.org/C67636389', 'wikidata': 'https://www.wikidata.org/wiki/Q784237', 'display_name': 'Genetic predisposition', 'level': 3, 'score': 0.41276315}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4016697}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39974758}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.35196817}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.28522047}, {'id': 'https://openalex.org/C197754878', 'wikidata': 'https://www.wikidata.org/wiki/Q80711', 'display_name': 'Haplotype', 'level': 4, 'score': 0.2696431}, {'id': 'https://openalex.org/C153209595', 'wikidata': 'https://www.wikidata.org/wiki/Q501128', 'display_name': 'Single-nucleotide polymorphism', 'level': 4, 'score': 0.22566497}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.22539964}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17336255}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.055379838}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2013-2545', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.79, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4211159162', 'https://openalex.org/W3083163488', 'https://openalex.org/W2478297712', 'https://openalex.org/W2441411273', 'https://openalex.org/W2080869830', 'https://openalex.org/W2060620036', 'https://openalex.org/W1985296731', 'https://openalex.org/W1980468882', 'https://openalex.org/W1971927498', 'https://openalex.org/W1514859281'], 'abstract_inverted_index': {'Abstract': [0], 'Adenocarcinoma': [1], '(AC)': [2], 'and': [3, 70, 84, 170, 184], 'squamous': [4, 238], 'cell': [5, 239], 'carcinoma': [6, 240], '(SqCC)': [7], 'are': [8], 'two': [9], 'major': [10], 'histological': [11, 38], 'subtypes': [12, 39], 'of': [13, 27, 40, 104, 152, 172, 178, 246, 251], 'lung': [14, 28, 41, 49, 64, 81, 105, 153, 173, 182, 206, 237], 'cancer.': [15], 'Genome-wide': [16, 226], 'association': [17, 167, 227], 'studies': [18], '(GWAS)': [19], 'have': [20, 51], 'made': [21], 'considerable': [22], 'advances': [23], 'in': [24, 46, 66, 78, 94, 175, 209, 241], 'the': [25, 59, 247, 252], 'understanding': [26], 'cancer': [29], 'susceptibility.': [30], 'Obvious': [31], 'heterogeneity': [32], 'has': [33], 'been': [34, 53], 'observed': [35], 'between': [36, 168], 'different': [37], 'cancer,': [42], 'but': [43], 'genetic': [44, 197], 'determinants': [45], 'specific': [47], 'to': [48, 205], 'SqCC': [50, 65, 68, 82, 106, 207], 'not': [52, 164], 'systematically': [54], 'investigated.': [55], 'Here,': [56], 'we': [57, 162], 'performed': [58], 'GWAS': [60], 'analysis': [61], 'specifically': [62, 203], 'for': [63, 236, 255], '833': [67], 'cases': [69, 83, 180], '3,094': [71], 'controls': [72, 86, 186], 'followed': [73], 'by': [74], 'a': [75, 133, 176, 230], 'two-stage': [76], 'replication': [77], 'additional': [79], '2,223': [80], '6,409': [85], 'from': [87], 'Chinese': [88, 210], 'populations.': [89], 'We': [90], 'found': [91], 'that': [92, 196], 'rs12296850': [93, 169], 'SLC17A8-NR1H4': [95], 'gene': [96], 'region': [97], 'at12q23.1': [98], 'was': [99], 'significantly': [100], 'associated': [101], 'with': [102, 158, 181], 'risk': [103, 151, 171], 'at': [107, 234], 'genome-wide': [108], 'significance': [109], 'level': [110], '[additive': [111], 'model:': [112], 'odds': [113], 'ratio': [114], '(OR)': [115], '=': [116, 122, 136, 140, 145, 148, 190], '0.78,': [117], '95%': [118, 138], 'confidence': [119], 'interval': [120], '(CI)': [121], '0.72-0.84,': [123], 'P=': [124], '1.19×10-10].': [125], 'Subjects': [126], 'carrying': [127], 'AG': [128], 'or': [129, 142], 'GG': [130], 'genotype': [131], 'had': [132], '26%': [134], '(OR': [135, 144], '0.74,': [137], 'CI': [139], '0.67-0.81)': [141], '32%': [143], '0.68,': [146], '95%CI': [147, 189], '0.56-0.83)': [149], 'decreased': [150], 'SqCC,': [154], 'respectively,': [155], 'as': [156], 'compared': [157], 'AA': [159], 'genotype.': [160], 'However,': [161], 'did': [163], 'observe': [165], 'significant': [166], 'AC': [174, 183], 'total': [177], '4,368': [179], '9,486': [185], '(OR=': [187], '0.96,': [188], '0.90-1.02,': [191], 'P=0.173).': [192], 'These': [193], 'results': [194], 'indicate': [195], 'variations': [198], 'on': [199], 'chromosome': [200], '12q23.1': [201, 235], 'may': [202], 'contribute': [204], 'susceptibility': [208, 232], 'population.': [211], 'Citation': [212], 'Format:': [213], 'Hongbing': [214], 'Shen,': [215], 'Jing': [216], 'Dong,': [217], 'Guangfu': [218], 'Jin,': [219], 'Minjie': [220], 'Chu,': [221], 'Dongxin': [222], 'Lin,': [223], 'Zhinbin': [224], 'Hu.': [225], 'study': [228], 'identifies': [229], 'novel': [231], 'locus': [233], 'Chinese.': [242], '[abstract].': [243], 'In:': [244], 'Proceedings': [245], '104th': [248], 'Annual': [249], 'Meeting': [250], 'American': [253], 'Association': [254], 'Cancer': [256, 266], 'Research;': [257], '2013': [258], 'Apr': [259], '6-10;': [260], 'Washington,': [261], 'DC.': [262], 'Philadelphia': [263], '(PA):': [264], 'AACR;': [265], 'Res': [267], '2013;73(8': [268], 'Suppl):Abstract': [269], 'nr': [270], '2545.': [271], 'doi:10.1158/1538-7445.AM2013-2545': [272]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1977469218', 'counts_by_year': [], 'updated_date': '2024-12-08T13:08:50.447143', 'created_date': '2016-06-24'}